The network for 'positive regulation of cell division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cell division

Any process that activates or increases the frequency, rate or extent of cell division.

NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.987
EGFRepidermal growth factor receptor0.969
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.945
CDC27cell division cycle 27 homolog (S. cerevisiae)0.910
CCNA2cyclin A20.873
PTPN1protein tyrosine phosphatase, non-receptor type 10.839
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.838
FGFR1fibroblast growth factor receptor 10.825
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.814
NCF1neutrophil cytosolic factor 10.770
PLK1polo-like kinase 10.764
ARHGAP10Rho GTPase activating protein 100.750
IL1R1interleukin 1 receptor, type I0.734
CCNB1cyclin B10.686
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.661
ANAPC4anaphase promoting complex subunit 40.592
CCR5chemokine (C-C motif) receptor 50.591
CCNB2cyclin B20.550
CDK2cyclin-dependent kinase 20.508
IRS1insulin receptor substrate 10.490
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.472
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.458
FGFR2fibroblast growth factor receptor 20.452
CDC23cell division cycle 23 homolog (S. cerevisiae)0.447
ORC2origin recognition complex, subunit 20.442
CD86CD86 molecule0.432
PRKCAprotein kinase C, alpha0.404
JUPjunction plakoglobin0.399
CDK1cyclin-dependent kinase 10.380
PTPRJprotein tyrosine phosphatase, receptor type, J0.363
CD80CD80 molecule0.362
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.349
AURKBaurora kinase B0.328
STON2stonin 20.327
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.326
CCL5chemokine (C-C motif) ligand 50.323
GRB10growth factor receptor-bound protein 100.318
CDC20cell division cycle 20 homolog (S. cerevisiae)0.313
ADORA2Aadenosine A2a receptor0.308
TPBGtrophoblast glycoprotein0.306
PRC1protein regulator of cytokinesis 10.305
PPP2R5Eprotein phosphatase 2, regulatory subunit B', epsilon isoform0.292
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.289
CENPFcentromere protein F, 350/400kDa (mitosin)0.286
RACGAP1Rac GTPase activating protein 10.280
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.277
JAK2Janus kinase 20.277
MARK3MAP/microtubule affinity-regulating kinase 30.260
PLCG1phospholipase C, gamma 10.258
NRP1neuropilin 10.254
RHOAras homolog gene family, member A0.253
HDAC6histone deacetylase 60.249
CDKN3cyclin-dependent kinase inhibitor 30.240
RB1retinoblastoma 10.236
IL2RBinterleukin 2 receptor, beta0.232
KRT14keratin 140.212
FUBP1far upstream element (FUSE) binding protein 10.210
ECT2epithelial cell transforming sequence 2 oncogene0.208
PSEN1presenilin 10.195
GAS2L3growth arrest-specific 2 like 30.181
ANAPC1anaphase promoting complex subunit 10.176
IL1R2interleukin 1 receptor, type II0.173
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.169
ORC3origin recognition complex, subunit 30.168
MIS18BP1MIS18 binding protein 10.159
TIMP3TIMP metallopeptidase inhibitor 30.156
FOXM1forkhead box M10.153
NEDD4neural precursor cell expressed, developmentally down-regulated 40.148
IFNGinterferon, gamma0.144
ARHGAP1Rho GTPase activating protein 10.142
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.138
ADRBK1adrenergic, beta, receptor kinase 10.138
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.132
CDCA8cell division cycle associated 80.123
INCENPinner centromere protein antigens 135/155kDa0.123
RLN3relaxin 30.121
MBNL1muscleblind-like (Drosophila)0.119
RBL1retinoblastoma-like 1 (p107)0.115
CSNK1Ecasein kinase 1, epsilon0.114
CCR2chemokine (C-C motif) receptor 20.114
RBL2retinoblastoma-like 2 (p130)0.111
KIF23kinesin family member 230.110
FGF10fibroblast growth factor 100.110
SMC3structural maintenance of chromosomes 30.109
TNFAIP1tumor necrosis factor, alpha-induced protein 1 (endothelial)0.109
DAZ1deleted in azoospermia 10.108
CAV1caveolin 1, caveolae protein, 22kDa0.106
LAIR1leukocyte-associated immunoglobulin-like receptor 10.103
METmet proto-oncogene (hepatocyte growth factor receptor)0.100
PGFplacental growth factor0.098
ERBB2IPerbb2 interacting protein0.097
SIRT2sirtuin 20.097
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.097
FGF7fibroblast growth factor 70.097
SRSF11serine/arginine-rich splicing factor 110.096
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.092
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
msxdmuscle segment homeobox D0.203
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.186
pax6apaired box gene 6a0.163
rhoabras homolog gene family, member Ab0.146
vasavasa homolog0.137
kif23kinesin family member 230.133
ccna2cyclin A20.125
ccnb1cyclin B10.124
arandrogen receptor0.107
ror2receptor tyrosine kinase-like orphan receptor 20.107
igf1rbinsulin-like growth factor 1b receptor0.107
her6hairy-related 60.103
shhasonic hedgehog a0.091
fgf3fibroblast growth factor 30.089
gng12aguanine nucleotide binding protein (G protein), gamma 12a0.087
fgfr3fibroblast growth factor receptor 30.084
ca15bcarbonic anhydrase XV b0.082
ascl1aachaete-scute complex-like 1a (Drosophila)0.082
rcn1reticulocalbin 1, EF-hand calcium binding domain0.077
cdc25cell division cycle 25 homolog0.070
opn1sw2opsin 1 (cone pigments), short-wave-sensitive 20.066
ncam2neural cell adhesion molecule 20.065
snai1asnail homolog 1a (Drosophila)0.064
tacc3transforming, acidic coiled-coil containing protein 30.064
g2e3G2/M-phase specific E3 ubiquitin ligase0.062
mbnl2muscleblind-like 2 (Drosophila)0.061
piwil1piwi-like 1 (Drosophila)0.061
hoxa10bhomeo box A10b0.061
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.060
dlx4adistal-less homeobox gene 4a0.056
unguracil-DNA glycosylase0.053
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.053
ip6k2inositol hexaphosphate kinase 20.052
tp53tumor protein p530.052
hoxa13bhomeo box A13b0.051
ncaphnon-SMC condensin I complex, subunit H0.051
cadm3cell adhesion molecule 30.050
tubg1tubulin, gamma 10.049
igfbp1ainsulin-like growth factor binding protein 1a0.049
runx2arunt-related transcription factor 2a0.049
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.048
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.048
ptpraprotein tyrosine phosphatase, receptor type, A0.047
LOC797832similar to signal peptide, CUB domain, EGF-like 10.047
piwil2piwi-like 2 (Drosophila)0.046
fshbfollicle stimulating hormone, beta polypeptide0.046
lrrtm1leucine rich repeat transmembrane neuronal 10.046
ripk2receptor-interacting serine-threonine kinase 20.045
tas2r200.1taste receptor, type 2, member 200.10.045
csnk1dbcasein kinase 1, delta b0.045
spry4sprouty (Drosophila) homolog 40.044
opn1sw1opsin 1 (cone pigments), short-wave-sensitive 10.044
kal1aKallmann syndrome 1a sequence0.044
prkd1protein kinase D10.044
gata1aGATA binding protein 1a0.043
wnt1wingless-type MMTV integration site family, member 10.042
slc15a1bsolute carrier family 15 (oligopeptide transporter), member 1b0.042
irf2bp2ainterferon regulatory factor 2 binding protein 2a0.041
ifnphi1interferon phi 10.041
il1binterleukin 1, beta and interleukin 1, beta0.041
igfbp3insulin-like growth factor binding protein 30.041
il6rinterleukin 6 receptor0.041
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.040
hcrthypocretin (orexin) neuropeptide precursor0.040
nkx2.2aNK2 transcription factor related 2a0.040
efna5bephrin A5b0.040
bmp8abone morphogenetic protein 8a0.039
dmrt3adoublesex and mab-3 related transcription factor 3a0.039
pomcaproopiomelanocortin a0.039
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.039
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.039
tas1r3taste receptor, type 1, member 30.039
nfe2l1nuclear factor, erythroid derived 2,-like 10.038
hoxa9bhomeo box A9b0.038
hoxa11bhomeo box A11b0.038
dbhdopamine beta hydroxylase0.038
rspo3R-spondin 3 homolog (Xenopus laevis)0.038
myo6bmyosin VIb0.037
bmp2abone morphogenetic protein 2a0.037
uxs1UDP-glucuronic acid decarboxylase 10.037
LOC557722similar to transient receptor potential cation channel, subfamily M, member 50.037
nr2f2nuclear receptor subfamily 2, group F, member 20.037
kctd15apotassium channel tetramerisation domain containing 15a0.037
ctsfcathepsin F0.037
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.037
alcambactivated leukocyte cell adhesion molecule b0.037
six3bsine oculis homeobox homolog 3b0.037
rapsnreceptor-associated protein of the synapse, 43kD0.036
igf1insulin-like growth factor 10.036
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
E(spl)Enhancer of split0.129
aspabnormal spindle0.126
HLHmgammaE(spl) region transcript mgamma0.066
HLHm5E(spl) region transcript m50.066
Pi3K92ECG4141 gene product from transcript CG4141-RB0.066
HLHmbetaE(spl) region transcript mbeta0.061
malphaE(spl) region transcript malpha0.056
HLHmdeltaE(spl) region transcript mdelta0.038
MadMothers against dpp0.031
Su(var)2-10Suppressor of variegation 2-100.022
Act5CActin 5C0.019
bratbrain tumor0.017
CycECyclin E0.017
HLHm7E(spl) region transcript m70.017
Nuf2CG8902 gene product from transcript CG8902-RA0.017
CycBCyclin B0.016
cdc23CG2508 gene product from transcript CG2508-RA0.016
emcextra macrochaetae0.015
stilstand still0.014
Vsx2CG33980 gene product from transcript CG33980-RA0.014
JIL-1CG6297 gene product from transcript CG6297-RA0.014
Su(H)Suppressor of Hairless0.014
cdc2CG5363 gene product from transcript CG5363-RA0.013
stumpsCG31317 gene product from transcript CG31317-RC0.013
mbcmyoblast city0.011
myoglianinCG1838 gene product from transcript CG1838-RD0.011
Rho1CG8416 gene product from transcript CG8416-RB0.011
HLHm3E(spl) region transcript m30.010
G-oalpha47AG protein oalpha 47A0.010
Cdc37CG12019 gene product from transcript CG12019-RA0.010
marsCG17064 gene product from transcript CG17064-RB0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Hoxa13homeobox A130.870
Ascl1achaete-scute complex homolog 1 (Drosophila)0.869
Trp53transformation related protein 530.663
Shhsonic hedgehog0.619
Adrb1adrenergic receptor, beta 10.572
Ccnb2cyclin B20.524
Drd2dopamine receptor D20.523
Nos3nitric oxide synthase 3, endothelial cell0.515
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.462
Pnpla2patatin-like phospholipase domain containing 20.413
Dkk1dickkopf homolog 1 (Xenopus laevis)0.405
Fgfr3fibroblast growth factor receptor 30.386
Ctnnb1catenin (cadherin associated protein), beta 10.386
Trim59tripartite motif-containing 590.382
Fgf8fibroblast growth factor 80.366
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.366
Plcg1phospholipase C, gamma 10.358
Ptpn11protein tyrosine phosphatase, non-receptor type 110.301
Vegfavascular endothelial growth factor A0.295
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.290
Ccnb1cyclin B10.288
Cdc25ccell division cycle 25 homolog C (S. pombe)0.287
Fgfr1fibroblast growth factor receptor 10.282
Otx2orthodenticle homolog 2 (Drosophila)0.277
Csf1colony stimulating factor 1 (macrophage)0.276
Grb10growth factor receptor bound protein 100.271
Msx1homeobox, msh-like 10.248
Hoxa10homeobox A100.245
Cdkn1bcyclin-dependent kinase inhibitor 1B0.243
Pax2paired box gene 20.238
Tgfb2transforming growth factor, beta 20.223
Cdk1cyclin-dependent kinase 10.213
Rac1RAS-related C3 botulinum substrate 10.200
Fshrfollicle stimulating hormone receptor0.200
Prrx2paired related homeobox 20.199
CblCasitas B-lineage lymphoma0.198
Hoxd13homeobox D130.195
Gja8gap junction protein, alpha 80.190
Ccna2cyclin A20.187
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.187
Lrp6low density lipoprotein receptor-related protein 60.182
Notch2Notch gene homolog 2 (Drosophila)0.176
Axin1axin 10.172
BrafBraf transforming gene0.170
Ube2cubiquitin-conjugating enzyme E2C0.170
Ptenphosphatase and tensin homolog0.167
Rargretinoic acid receptor, gamma0.161
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.158
Prc1protein regulator of cytokinesis 10.155
Fzr1fizzy/cell division cycle 20 related 1 (Drosophila)0.153
Csf3colony stimulating factor 3 (granulocyte)0.152
Pthlhparathyroid hormone-like peptide0.147
Ldb3LIM domain binding 30.146
Prrx1paired related homeobox 10.145
Rb1retinoblastoma 10.145
Gsk3bglycogen synthase kinase 3 beta0.139
Kif22kinesin family member 220.139
Fgfr2fibroblast growth factor receptor 20.137
Ppargperoxisome proliferator activated receptor gamma0.135
Pax9paired box gene 90.134
Igf1rinsulin-like growth factor I receptor0.134
Notch1Notch gene homolog 1 (Drosophila)0.127
Zeb1zinc finger E-box binding homeobox 10.126
En2engrailed 20.123
Wnt10bwingless related MMTV integration site 10b0.122
Foxc2forkhead box C20.121
Neurod1neurogenic differentiation 10.116
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.116
Birc5baculoviral IAP repeat-containing 50.116
Htr45 hydroxytryptamine (serotonin) receptor 40.112
Kif20akinesin family member 20A0.111
MecomMDS1 and EVI1 complex locus0.109
Emx1empty spiracles homolog 1 (Drosophila)0.108
Foxc1forkhead box C10.107
Prkccprotein kinase C, gamma0.103
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.100
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.098
Smosmoothened homolog (Drosophila)0.096
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.095
Onecut1one cut domain, family member 10.093
Cdkn3cyclin-dependent kinase inhibitor 30.091
Bmp7bone morphogenetic protein 70.090
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.090
Pax3paired box gene 30.089
Foxg1forkhead box G10.088
Racgap1Rac GTPase-activating protein 10.088
Lmx1bLIM homeobox transcription factor 1 beta0.088
Nf1neurofibromatosis 10.087
Alx4aristaless-like homeobox 40.086
Acvr1activin A receptor, type 10.085
Ikzf1IKAROS family zinc finger 10.085
Wnt1wingless-related MMTV integration site 10.084
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.084
Eya4eyes absent 4 homolog (Drosophila)0.083
En1engrailed 10.082
Flt4FMS-like tyrosine kinase 40.082
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YPL014Whypothetical protein0.014
YLR297Whypothetical protein0.012