The network for 'chloride transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chloride transport

The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NameDescriptionProbabilityFunc Analog Organism
GOPCgolgi-associated PDZ and coiled-coil motif containing0.995
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.973
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.940
PDZK1PDZ domain containing 10.898
KLHL3kelch-like 3 (Drosophila)0.841
SLC7A5solute carrier family 7 (cationic amino acid transporter, y+ system), member 50.515
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.470
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.355
APOL1apolipoprotein L, 10.330
USP50ubiquitin specific peptidase 500.194
RARRES3retinoic acid receptor responder (tazarotene induced) 30.180
OXSR1oxidative-stress responsive 10.150
PRKCGprotein kinase C, gamma0.119
STK39serine threonine kinase 390.115
APOL3apolipoprotein L, 30.111
EPB42erythrocyte membrane protein band 4.20.109
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.105
PLP2proteolipid protein 2 (colonic epithelium-enriched)0.100
APOL2apolipoprotein L, 20.098
UGT2B7UDP glucuronosyltransferase 2 family, polypeptide B70.098
GFAPglial fibrillary acidic protein0.096
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.090
CA4carbonic anhydrase IV0.088
OPRK1opioid receptor, kappa 10.080
ANXA2annexin A20.078
CLCN3chloride channel 30.077
SLC38A7solute carrier family 38, member 70.074
BST2bone marrow stromal cell antigen 20.064
MPDU1mannose-P-dolichol utilization defect 10.063
TAGLN2transgelin 20.062
TRAM1translocation associated membrane protein 10.060
GBP4guanylate binding protein 40.059
APOL6apolipoprotein L, 60.059
SCARB2scavenger receptor class B, member 20.053
IL1RAPL1interleukin 1 receptor accessory protein-like 10.050
SLITRK3SLIT and NTRK-like family, member 30.049
DRD5dopamine receptor D50.049
TBC1D10ATBC1 domain family, member 10A0.049
GPC5glypican 50.044
SV2Csynaptic vesicle glycoprotein 2C0.043
IL15RAinterleukin 15 receptor, alpha0.043
PLOD3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.041
SLC6A13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.041
ELOVL1elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 10.040
LMF2lipase maturation factor 20.040
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.040
KCNJ1potassium inwardly-rectifying channel, subfamily J, member 10.039
RALYLRALY RNA binding protein-like0.038
GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 20.038
TMEM106Btransmembrane protein 106B0.038
GRINAglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.037
ENGASEendo-beta-N-acetylglucosaminidase0.037
C9orf5chromosome 9 open reading frame 50.037
BCRbreakpoint cluster region0.036
SLC24A2solute carrier family 24 (sodium/potassium/calcium exchanger), member 20.036
GIMAP6GTPase, IMAP family member 60.036
CDH10cadherin 10, type 2 (T2-cadherin)0.036
RYR2ryanodine receptor 2 (cardiac)0.035
SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 10.034
FABP7fatty acid binding protein 7, brain0.033
GRIA1glutamate receptor, ionotropic, AMPA 10.033
SEPN1selenoprotein N, 10.033
GABRQgamma-aminobutyric acid (GABA) receptor, theta0.033
SLC9A2solute carrier family 9 (sodium/hydrogen exchanger), member 20.032
GNG4guanine nucleotide binding protein (G protein), gamma 40.032
SCAMP1secretory carrier membrane protein 10.032
LY6Dlymphocyte antigen 6 complex, locus D0.031
NHLH2nescient helix loop helix 20.031
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.030
GLRA1glycine receptor, alpha 10.030
CD63CD63 molecule0.029
GPR12G protein-coupled receptor 120.029
HTR5A5-hydroxytryptamine (serotonin) receptor 5A0.029
SNTG1syntrophin, gamma 10.028
DSC3desmocollin 30.028
TP53TG5TP53 target 50.028
GRIA2glutamate receptor, ionotropic, AMPA 20.028
KHDRBS2KH domain containing, RNA binding, signal transduction associated 20.027
KLK6kallikrein-related peptidase 60.027
SEPT10septin 100.027
PROL1proline rich, lacrimal 10.026
MYCNv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.026
IFI35interferon-induced protein 350.025
NEK6NIMA (never in mitosis gene a)-related kinase 60.025
SPTBspectrin, beta, erythrocytic0.025
MUC13mucin 13, cell surface associated0.025
PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.025
BTN3A1butyrophilin, subfamily 3, member A10.024
LASS2LAG1 homolog, ceramide synthase 20.024
HTR2A5-hydroxytryptamine (serotonin) receptor 2A0.024
PYCR1pyrroline-5-carboxylate reductase 10.024
GABRA6gamma-aminobutyric acid (GABA) A receptor, alpha 60.023
LRRN2leucine rich repeat neuronal 20.023
TMEM179transmembrane protein 1790.022
BTN3A3butyrophilin, subfamily 3, member A30.022
AP3B2adaptor-related protein complex 3, beta 2 subunit0.022
CEACAM7carcinoembryonic antigen-related cell adhesion molecule 70.022
CTNScystinosis, nephropathic0.022
SCN2Asodium channel, voltage-gated, type II, alpha subunit0.022
PURGpurine-rich element binding protein G0.022
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
sax-7Protein SAX-70.029
mlt-7Protein MLT-70.023
glr-5Protein GLR-50.022
twk-17Protein TWK-170.019
mec-4Protein MEC-40.016
F46H5.7Protein F46H5.70.015
F02D8.4Protein F02D8.40.014
cka-2Protein CKA-20.013
pkg-1Protein PKG-10.013
F21D12.3Protein F21D12.30.013
cpna-1Protein CPNA-10.013
trp-1Protein TRP-10.012
C54D10.5Protein C54D10.50.012
sul-2Protein SUL-20.011
myo-6Protein MYO-60.011
unc-46Protein UNC-460.011
xbx-3Protein XBX-30.010
ntl-4Protein NTL-40.010
clec-7Protein CLEC-70.010
F23H11.6Protein F23H11.60.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
trpv6transient receptor potential cation channel, subfamily V, member 60.942
rhagRhesus blood group-associated glycoprotein0.852
ca2carbonic anhydrase II0.848
slc12a10.2solute carrier family 12 (sodium/potassium/chloride transporters), member 10.20.779
slc4a4bsolute carrier family 4, sodium bicarbonate cotransporter, member 4b0.580
pdzk1PDZ domain containing 10.489
cdh17cadherin 17, LI cadherin (liver-intestine)0.481
aqp1a.1aquaporin 1a, tandem duplicate 10.384
slc26a3solute carrier family 26, member 30.298
slc20a1asolute carrier family 20, member 1a0.272
lcp1lymphocyte cytosolic plastin 10.261
nt5c2l15'-nucleotidase, cytosolic II, like 10.231
slc26a4solute carrier family 26, member 40.222
glulaglutamate-ammonia ligase (glutamine synthase) a0.193
gad2glutamate decarboxylase 20.128
slc4a1bsolute carrier family 4, anion exchanger, member 1b0.126
ca15acarbonic anhydrase XV a0.123
rhcgl1Rhesus blood group, C glycoprotein, like 10.120
slc12a3solute carrier family 12 (sodium/chloride transporters), member 30.118
tfatransferrin-a0.085
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.082
eporerythropoietin receptor0.080
hbaa1hemoglobin alpha adult-10.073
fbxo45F-box protein 450.069
elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.068
pou4f2POU domain, class 4, transcription factor 20.065
rhbgRhesus blood group, B glycoprotein0.054
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.048
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.048
slc9a3.2solute carrier family 9 (sodium/hydrogen exchanger), member 3.20.046
cx27.5connexin 27.50.044
slc9a3r1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.041
rgs4regulator of G-protein signalling 40.040
si:ch211-284e13.2si:ch211-284e13.20.039
slc4a4asolute carrier family 4, member 4a0.036
ndrg1N-myc downstream regulated gene 10.036
LOC100005108novel protein similar to solute carrier family 26, member 5 (slc26a5)0.036
slc2a12solute carrier family 2 (facilitated glucose transporter), member 120.035
emilin1aelastin microfibril interfacer 1a0.034
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.033
gabbr1agamma-aminobutyric acid (GABA) B receptor, 1a0.033
hnf1bbHNF1 homeobox Bb0.030
efna1bephrin A1b0.027
gnrh2gonadotropin-releasing hormone 20.025
col19a1collagen, type XIX, alpha 10.025
nr3c2nuclear receptor subfamily 3, group C, member 20.025
ugt1b1UDP glucuronosyltransferase 1 family, polypeptide B10.024
zgc:153012zgc:1530120.024
rnft1ring finger protein, transmembrane 10.024
anxa11bannexin A11b0.024
kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.024
slc8a4asolute carrier family 8 (sodium/calcium exchanger), member 4a0.023
alas2aminolevulinate, delta-, synthetase 20.023
atp2b4ATPase, Ca++ transporting, plasma membrane 40.022
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.022
egfepidermal growth factor0.022
synj1synaptojanin 10.021
adipor2adiponectin receptor 20.021
zgc:64141zgc:641410.020
epas1bendothelial PAS domain protein 1b0.019
npyneuropeptide Y0.019
nucb2bnucleobindin 2b0.019
wnt7bbwingless-type MMTV integration site family, member 7Bb0.018
coro1acoronin, actin binding protein, 1A0.018
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.017
foxi3aforkhead box I3a0.016
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.016
LOC100001008prepro-urotensin II-related peptide0.016
has3hyaluronan synthase 30.016
slc4a2asolute carrier family 4, anion exchanger, member 2a0.015
pou3f3aPOU class 3 homeobox 3a0.015
atp2b3aATPase, Ca++ transporting, plasma membrane 3a0.014
tkttransketolase0.014
slc39a1solute carrier family 39 (zinc transporter), member 10.014
foxi3bforkhead box I3b0.013
irx3biroquois homeobox protein 3b0.013
blvrbbiliverdin reductase B (flavin reductase (NADPH))0.013
pyyapeptide YYa0.013
nppclnatriuretic peptide precursor C-like protein0.013
atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.012
slc40a1solute carrier family 40 (iron-regulated transporter), member 10.012
c1qtnf4C1q and tumor necrosis factor related protein 40.012
slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.012
LOC100534776toll-like receptor 7-like0.012
acat1acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)0.012
sult2st1sulfotransferase family 2, cytosolic sulfotransferase 10.012
sdf4stromal cell derived factor 40.012
slc8a1bsolute carrier family 8 (sodium/calcium exchanger), member 1b0.011
crb2acrumbs homolog 2a0.011
grin1aglutamate receptor, ionotropic, N-methyl D-aspartate 1a0.011
slc18a3asolute carrier family 18 (vesicular acetylcholine), member 3a0.011
klfdKruppel-like factor d0.011
gatsl2GATS protein-like 20.011
ca8carbonic anhydrase VIII0.011
LOC100003911chemokine CXCL-C13d0.011
pvalb7parvalbumin 70.011
esrrgaestrogen-related receptor gamma a0.011
tpi1btriosephosphate isomerase 1b0.010
cyb5r3cytochrome b5 reductase 30.010
plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
sdaslamdance0.187
tipEtemperature-induced paralytic E0.085
GrafCG8948 gene product from transcript CG8948-RB0.068
ShabShaker cognate b0.038
CG7536CG7536 gene product from transcript CG7536-RB0.029
MESK2Misexpression suppressor of KSR 20.028
a5antennal protein 50.026
CG15267CG15267 gene product from transcript CG15267-RA0.023
CG2893CG2893 gene product from transcript CG2893-RE0.022
AnkAnkyrin0.019
ineinebriated0.017
CG7806CG7806 gene product from transcript CG7806-RA0.016
MAPk-Ak2MAP kinase activated protein-kinase-20.015
kdnknockdown0.015
CG13384CG13384 gene product from transcript CG13384-RJ0.014
Hydr2alpha/beta hydrolase20.014
CG7112CG7112 gene product from transcript CG7112-RB0.014
GluRIIEGlutamate receptor IIE0.013
AldAldolase0.012
Mpk2CG5475 gene product from transcript CG5475-RB0.012
Aplip1APP-like protein interacting protein 10.011
axoaxotactin0.010
VGATVesicular GABA Transporter0.010
Ncc69sodium chloride cotransporter 690.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gabrb2gamma-aminobutyric acid (GABA) A receptor, subunit beta 20.999
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.994
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.978
Slc12a1solute carrier family 12, member 10.972
Slc4a7solute carrier family 4, sodium bicarbonate cotransporter, member 70.966
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.930
Grid1glutamate receptor, ionotropic, delta 10.907
Slc4a4solute carrier family 4 (anion exchanger), member 40.894
Gabra5gamma-aminobutyric acid (GABA) A receptor, subunit alpha 50.794
Cftrcystic fibrosis transmembrane conductance regulator homolog0.704
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.692
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.678
Slc12a5solute carrier family 12, member 50.659
Slc26a4solute carrier family 26, member 40.622
Slc12a2solute carrier family 12, member 20.600
Thrbthyroid hormone receptor beta0.523
Slc12a6solute carrier family 12, member 60.458
Slc26a7solute carrier family 26, member 70.458
BsndBartter syndrome, infantile, with sensorineural deafness (Barttin)0.387
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.354
Slc26a3solute carrier family 26, member 30.307
Umoduromodulin0.285
Gad2glutamic acid decarboxylase 20.272
Gabra1gamma-aminobutyric acid (GABA) A receptor, subunit alpha 10.233
Slc4a1solute carrier family 4 (anion exchanger), member 10.225
NdpNorrie disease (pseudoglioma) (human)0.217
Scnn1bsodium channel, nonvoltage-gated 1 beta0.195
Slc13a1solute carrier family 13 (sodium/sulfate symporters), member 10.186
Sectm1bsecreted and transmembrane 1B0.157
En2engrailed 20.155
Cdh9cadherin 90.133
Kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.132
Slc6a20bsolute carrier family 6 (neurotransmitter transporter), member 20B0.125
Gdf3growth differentiation factor 30.124
Neurod1neurogenic differentiation 10.124
Ren1renin 1 structural0.122
Gabrg2gamma-aminobutyric acid (GABA) A receptor, subunit gamma 20.116
Ank1ankyrin 1, erythroid0.113
Mas1MAS1 oncogene0.111
RhagRhesus blood group-associated A glycoprotein0.109
Ryr3ryanodine receptor 30.108
Gabra6gamma-aminobutyric acid (GABA) A receptor, subunit alpha 60.106
Nxph1neurexophilin 10.103
Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 20.100
Oprk1opioid receptor, kappa 10.095
LOC100503041PDZ domain-containing protein 7-like0.093
Gabrg1gamma-aminobutyric acid (GABA) A receptor, subunit gamma 10.093
Ccr3chemokine (C-C motif) receptor 30.090
Camk4calcium/calmodulin-dependent protein kinase IV0.089
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.087
Svs3aseminal vesicle secretory protein 3A0.083
Hsd11b2hydroxysteroid 11-beta dehydrogenase 20.083
Cdkn2dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)0.082
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.080
Galr1galanin receptor 10.077
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.075
Npy6rneuropeptide Y receptor Y60.075
Glg1golgi apparatus protein 10.068
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.067
Mogat2monoacylglycerol O-acyltransferase 20.066
Gabrb1gamma-aminobutyric acid (GABA) A receptor, subunit beta 10.063
Kcnk3potassium channel, subfamily K, member 30.062
Smyd1SET and MYND domain containing 10.061
Glagalactosidase, alpha0.060
Aqp4aquaporin 40.059
Mgat4cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)0.059
St14suppression of tumorigenicity 14 (colon carcinoma)0.058
Slc6a18solute carrier family 6 (neurotransmitter transporter), member 180.056
Brs3bombesin-like receptor 30.056
Clrn1clarin 10.056
Gypaglycophorin A0.055
Krt86keratin 860.055
Otosotospiralin0.054
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.051
Ppp1r1bprotein phosphatase 1, regulatory (inhibitor) subunit 1B0.051
Duoxa2dual oxidase maturation factor 20.050
Kcnd2potassium voltage-gated channel, Shal-related family, member 20.050
Pip5k1bphosphatidylinositol-4-phosphate 5-kinase, type 1 beta0.049
Calb1calbindin 10.048
Pkhd1l1polycystic kidney and hepatic disease 1-like 10.047
Pou3f4POU domain, class 3, transcription factor 40.047
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.044
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.044
Tac1tachykinin 10.044
Csf3colony stimulating factor 3 (granulocyte)0.042
Scn1asodium channel, voltage-gated, type I, alpha0.042
Slitrk6SLIT and NTRK-like family, member 60.042
Ceacam11carcinoembryonic antigen-related cell adhesion molecule 110.041
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.041
Slc22a13solute carrier family 22 (organic cation transporter), member 130.041
Ceacam16carcinoembryonic antigen-related cell adhesion molecule 160.040
Cldn15claudin 150.040
Myo6myosin VI0.039
Ntng1netrin G10.038
Scn8asodium channel, voltage-gated, type VIII, alpha0.038
Wnk4WNK lysine deficient protein kinase 40.038
Ptprrprotein tyrosine phosphatase, receptor type, R0.037
Col19a1collagen, type XIX, alpha 10.037
Tyrp1tyrosinase-related protein 10.037
Epxeosinophil peroxidase0.037
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism