The network for 'regulation of cell cycle checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cell cycle checkpoint

Any process that modulates the frequency, rate or extent of cell cycle checkpoint.

NameDescriptionProbabilityFunc Analog Organism
TCP1t-complex 10.427
CCT8chaperonin containing TCP1, subunit 8 (theta)0.160
THOC4THO complex 40.083
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.079
RPA3replication protein A3, 14kDa0.078
THOC2THO complex 20.058
THOC1THO complex 10.046
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.041
THOC5THO complex 50.037
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.036
STARD9StAR-related lipid transfer (START) domain containing 90.033
CCT4chaperonin containing TCP1, subunit 4 (delta)0.033
CUL2cullin 20.030
RPA1replication protein A1, 70kDa0.030
TP53tumor protein p530.029
BRCA2breast cancer 2, early onset0.028
ANAPC4anaphase promoting complex subunit 40.023
PPP4Cprotein phosphatase 4, catalytic subunit0.018
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.017
STRN4striatin, calmodulin binding protein 40.017
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.015
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.015
FXR2fragile X mental retardation, autosomal homolog 20.015
CHTOPchromatin target of PRMT10.015
RFWD2ring finger and WD repeat domain 20.015
CCNT1cyclin T10.014
MESDC2mesoderm development candidate 20.014
HNF4Ahepatocyte nuclear factor 4, alpha0.013
HERC2hect domain and RLD 20.013
PRRC2Cproline-rich coiled-coil 2C0.013
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.013
SARNPSAP domain containing ribonucleoprotein0.012
THOC7THO complex 7 homolog (Drosophila)0.012
CDC20cell division cycle 20 homolog (S. cerevisiae)0.012
JMJD6jumonji domain containing 60.012
BTBD2BTB (POZ) domain containing 20.011
TUBA1Ctubulin, alpha 1c0.011
C19orf39chromosome 19 open reading frame 390.011
FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 10.010
AURKBaurora kinase B0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
dppdecapentaplegic0.079
DlDelta0.065
mRpL49mitochondrial ribosomal protein L490.035
Rho1CG8416 gene product from transcript CG8416-RB0.031
Fas2Fasciclin 20.028
Rac1CG2248 gene product from transcript CG2248-RA0.027
EgfrEpidermal growth factor receptor0.027
saxsaxophone0.023
dxdeltex0.022
armarmadillo0.022
cicubitus interruptus0.022
putpunt0.019
glglass0.019
TorTarget of rapamycin0.018
wgwingless0.018
phlpole hole0.018
AxnAxin0.017
CG18624CG18624 gene product from transcript CG18624-RC0.017
MoeMoesin0.017
CG30349CG30349 gene product from transcript CG30349-RA0.016
eyaeyes absent0.014
VangVan Gogh0.014
mit(1)15mitotic 150.013
dpdumpy0.013
CG7181CG7181 gene product from transcript CG7181-RA0.013
CG13993CG13993 gene product from transcript CG13993-RA0.013
CG3446CG3446 gene product from transcript CG3446-RA0.012
gbbglass bottom boat0.012
LamLamin0.012
dockdreadlocks0.012
FK506-bp2FK506-binding protein 20.012
Rab11Rab-protein 110.012
brmbrahma0.011
hpohippo0.011
GugGrunge0.011
l(2)06225lethal (2) 062250.011
dlg1discs large 10.011
ATPsyn-bATP synthase, subunit b0.010
hhhedgehog0.010
CG9172CG9172 gene product from transcript CG9172-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Per2period homolog 2 (Drosophila)1.000
Arntlaryl hydrocarbon receptor nuclear translocator-like1.000
Clockcircadian locomotor output cycles kaput1.000
Per1period homolog 1 (Drosophila)0.999
Cry1cryptochrome 1 (photolyase-like)0.998
Cry2cryptochrome 2 (photolyase-like)0.995
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.584
Csnk1ecasein kinase 1, epsilon0.369
Kif22kinesin family member 220.330
Brd2bromodomain containing 20.306
Npas2neuronal PAS domain protein 20.288
Per3period homolog 3 (Drosophila)0.253
Usp2ubiquitin specific peptidase 20.232
Sgol2shugoshin-like 2 (S. pombe)0.158
Cdk9cyclin-dependent kinase 9 (CDC2-related kinase)0.135
Trmt2aTRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)0.124
Lin28alin-28 homolog A (C. elegans)0.106
Cks2CDC28 protein kinase regulatory subunit 20.093
Rfc3replication factor C (activator 1) 30.081
Mitfmicrophthalmia-associated transcription factor0.072
Kif20akinesin family member 20A0.071
CrebbpCREB binding protein0.066
C330027C09RikRIKEN cDNA C330027C09 gene0.056
Scribscribbled homolog (Drosophila)0.053
Srrm1serine/arginine repetitive matrix 10.053
Zbtb37zinc finger and BTB domain containing 370.053
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.049
Trraptransformation/transcription domain-associated protein0.047
Reps1RalBP1 associated Eps domain containing protein0.047
Ccnb1cyclin B10.045
Rnf7ring finger protein 70.044
Psmc3ipproteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein0.043
Pcnaproliferating cell nuclear antigen0.043
Hdac1histone deacetylase 10.041
Prpf8pre-mRNA processing factor 80.039
Ewsr1Ewing sarcoma breakpoint region 10.038
Safbscaffold attachment factor B0.037
Chd4chromodomain helicase DNA binding protein 40.036
Varsvalyl-tRNA synthetase0.036
Eif2c2eukaryotic translation initiation factor 2C, 20.035
Trim28tripartite motif-containing 280.033
Xab2XPA binding protein 20.032
H2afxH2A histone family, member X0.029
Ints9integrator complex subunit 90.029
Fbxl3F-box and leucine-rich repeat protein 30.028
Lrrc40leucine rich repeat containing 400.027
Dnajc9DnaJ (Hsp40) homolog, subfamily C, member 90.027
Pcid2PCI domain containing 20.025
4632434I11RikRIKEN cDNA 4632434I11 gene0.024
Cul4acullin 4A0.023
Whsc2Wolf-Hirschhorn syndrome candidate 2 (human)0.023
Cdk1cyclin-dependent kinase 10.023
Srsf4serine/arginine-rich splicing factor 40.023
Birc5baculoviral IAP repeat-containing 50.021
Neurod1neurogenic differentiation 10.021
Zfp598zinc finger protein 5980.021
Gmnngeminin0.020
Alkbh1alkB, alkylation repair homolog 1 (E. coli)0.019
Larp7La ribonucleoprotein domain family, member 70.019
Nup188nucleoporin 1880.019
Thoc4THO complex 40.019
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.019
Scaf4SR-related CTD-associated factor 40.018
Ofd1oral-facial-digital syndrome 1 gene homolog (human)0.018
Cpsf1cleavage and polyadenylation specific factor 10.018
Atf6bactivating transcription factor 6 beta0.017
Tefthyrotroph embryonic factor0.017
Rbm10RNA binding motif protein 100.017
Bptfbromodomain PHD finger transcription factor0.017
Snrpasmall nuclear ribonucleoprotein polypeptide A0.016
Upf2UPF2 regulator of nonsense transcripts homolog (yeast)0.016
Ube2tubiquitin-conjugating enzyme E2T (putative)0.016
Zc3h18zinc finger CCCH-type containing 180.016
Lin9lin-9 homolog (C. elegans)0.016
Ccdc59coiled-coil domain containing 590.016
Puf60poly-U binding splicing factor 600.016
Cdkn2aipnlCDKN2A interacting protein N-terminal like0.015
Mat2amethionine adenosyltransferase II, alpha0.015
Nfatc3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 30.014
Acin1apoptotic chromatin condensation inducer 10.014
H2afyH2A histone family, member Y0.014
Lin28blin-28 homolog B (C. elegans)0.014
Skp2S-phase kinase-associated protein 2 (p45)0.013
Fen1flap structure specific endonuclease 10.012
Zfp317zinc finger protein 3170.012
Ino80eINO80 complex subunit E0.012
Ranbp3RAN binding protein 30.012
Nup50nucleoporin 500.011
Asxl1additional sex combs like 1 (Drosophila)0.011
Xpo6exportin 60.011
Rnaseh2aribonuclease H2, large subunit0.011
Rbx1ring-box 10.011
Ccne2cyclin E20.011
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.011
Eftud2elongation factor Tu GTP binding domain containing 20.011
Nup37nucleoporin 370.011
Slc2a1solute carrier family 2 (facilitated glucose transporter), member 10.011
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.010
Edc4enhancer of mRNA decapping 40.010
Prkcaprotein kinase C, alpha0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PPH22Pph22p0.554
PPH21Pph21p0.439
TIP41Tip41p0.106
PSY4Psy4p0.032
RFA1Rfa1p0.028
MAD3Mad3p0.022
ZDS1Zds1p0.018
NBL1Nbl1p0.018
RFA3Rfa3p0.017
SRD1Srd1p0.016
YLR264C-Ahypothetical protein0.016
PSY2Psy2p0.015
ORC6Orc6p0.014
LEU2Leu2p0.014
YLR162Whypothetical protein0.014
MER1Mer1p0.014
YOL038C-Ahypothetical protein0.013
CUP1-1Cup1-1p0.013
TPD3Tpd3p0.013
GBP2Gbp2p0.013
CDC20Cdc20p0.012
ARP10Arp10p0.012
SWC7Swc7p0.012
ARG8Arg8p0.011
CRP1Crp1p0.011
YPR157Whypothetical protein0.011
ZPS1Zps1p0.011
YAR068Whypothetical protein0.011
BUB3Bub3p0.011
ATP6Atp6p0.010
MTW1Mtw1p0.010
URA3Ura3p0.010
SPL2Spl2p0.010
YLR042Chypothetical protein0.010