The network for 'vitamin e metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

vitamin e metabolic process

The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.

NameDescriptionProbabilityFunc Analog Organism
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 21.000
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.979
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.975
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.812
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.714
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.644
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.571
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.475
C8Acomplement component 8, alpha polypeptide0.366
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.366
SULT1B1sulfotransferase family, cytosolic, 1B, member 10.304
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.302
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.297
KNG1kininogen 10.277
ADH6alcohol dehydrogenase 6 (class V)0.241
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.240
APOEapolipoprotein E0.225
SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.225
MASP2mannan-binding lectin serine peptidase 20.203
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.190
MAT1Amethionine adenosyltransferase I, alpha0.188
PLGplasminogen0.171
G6PCglucose-6-phosphatase, catalytic subunit0.166
GLYATglycine-N-acyltransferase0.155
C4BPAcomplement component 4 binding protein, alpha0.149
HNF4Ahepatocyte nuclear factor 4, alpha0.145
SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.136
BHMTbetaine--homocysteine S-methyltransferase0.124
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.122
FABP1fatty acid binding protein 1, liver0.122
FUT6fucosyltransferase 6 (alpha (1,3) fucosyltransferase)0.117
C8Bcomplement component 8, beta polypeptide0.102
RDH16retinol dehydrogenase 16 (all-trans)0.097
HALhistidine ammonia-lyase0.094
PAHphenylalanine hydroxylase0.091
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.089
DIO1deiodinase, iodothyronine, type I0.086
F9coagulation factor IX0.078
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.077
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.073
AZGP1alpha-2-glycoprotein 1, zinc-binding0.069
FETUBfetuin B0.068
GSTA3glutathione S-transferase alpha 30.067
HPhaptoglobin0.064
ARG1arginase, liver0.064
SULT1E1sulfotransferase family 1E, estrogen-preferring, member 10.061
OTCornithine carbamoyltransferase0.059
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 80.058
AADACarylacetamide deacetylase (esterase)0.058
HRGhistidine-rich glycoprotein0.057
DAOD-amino-acid oxidase0.053
SERPINA6serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 60.052
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.051
DEFB1defensin, beta 10.051
LIPClipase, hepatic0.049
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.049
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.045
GPX2glutathione peroxidase 2 (gastrointestinal)0.043
HAO1hydroxyacid oxidase (glycolate oxidase) 10.042
C6complement component 60.041
CYP4F8cytochrome P450, family 4, subfamily F, polypeptide 80.041
PRLRprolactin receptor0.041
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.040
CDHR5cadherin-related family member 50.039
SCNN1Bsodium channel, nonvoltage-gated 1, beta0.038
F13Bcoagulation factor XIII, B polypeptide0.038
HPD4-hydroxyphenylpyruvate dioxygenase0.037
CYP4A22cytochrome P450, family 4, subfamily A, polypeptide 220.037
APOC3apolipoprotein C-III0.037
NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase)0.036
BAATbile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)0.035
PIPOXpipecolic acid oxidase0.035
CYP2J2cytochrome P450, family 2, subfamily J, polypeptide 20.034
CEACAM8carcinoembryonic antigen-related cell adhesion molecule 80.034
ADH1Aalcohol dehydrogenase 1A (class I), alpha polypeptide0.033
AKR1D1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)0.033
SULT2B1sulfotransferase family, cytosolic, 2B, member 10.033
SCGB2A1secretoglobin, family 2A, member 10.032
CPB2carboxypeptidase B2 (plasma)0.031
IL22RA1interleukin 22 receptor, alpha 10.031
EPHX2epoxide hydrolase 2, cytoplasmic0.031
AFMafamin0.031
AGXT2L1alanine-glyoxylate aminotransferase 2-like 10.030
FMO4flavin containing monooxygenase 40.030
SLC22A1solute carrier family 22 (organic cation transporter), member 10.030
GBA3glucosidase, beta, acid 3 (cytosolic)0.029
SPP2secreted phosphoprotein 2, 24kDa0.029
SLCO1B3solute carrier organic anion transporter family, member 1B30.029
C9complement component 90.029
ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide0.028
CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)0.028
MTTPmicrosomal triglyceride transfer protein0.027
ANGPTL3angiopoietin-like 30.027
ALDH1L1aldehyde dehydrogenase 1 family, member L10.027
TMPRSS4transmembrane protease, serine 40.027
PIPprolactin-induced protein0.026
CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 10.024
HGDhomogentisate 1,2-dioxygenase0.023
C4BPBcomplement component 4 binding protein, beta0.023
CRPC-reactive protein, pentraxin-related0.023
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism