The network for 'neuromuscular junction development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuromuscular junction development

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.

NameDescriptionProbabilityFunc Analog Organism
FOSFBJ murine osteosarcoma viral oncogene homolog0.985
NCK1NCK adaptor protein 10.977
FYNFYN oncogene related to SRC, FGR, YES0.961
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.949
JUNjun proto-oncogene0.948
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.908
SMAD1SMAD family member 10.891
KIAA1377KIAA13770.878
SPRR2Asmall proline-rich protein 2A0.868
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.856
EGFRepidermal growth factor receptor0.854
MTORmechanistic target of rapamycin (serine/threonine kinase)0.852
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.821
GRB2growth factor receptor-bound protein 20.812
MAPK12mitogen-activated protein kinase 120.794
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.794
DLG4discs, large homolog 4 (Drosophila)0.787
DVL3dishevelled, dsh homolog 3 (Drosophila)0.769
MAPK8mitogen-activated protein kinase 80.754
AKT1v-akt murine thymoma viral oncogene homolog 10.752
FGFR1fibroblast growth factor receptor 10.717
PRMT1protein arginine methyltransferase 10.707
ADAM19ADAM metallopeptidase domain 190.675
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.670
PPFIA1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 10.663
DAAM1dishevelled associated activator of morphogenesis 10.657
PRKCAprotein kinase C, alpha0.655
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.638
WIPF1WAS/WASL interacting protein family, member 10.612
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.603
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.594
COL4A2collagen, type IV, alpha 20.593
GDAguanine deaminase0.592
LAMC1laminin, gamma 1 (formerly LAMB2)0.589
APBA1amyloid beta (A4) precursor protein-binding, family A, member 10.584
PPP2R5Dprotein phosphatase 2, regulatory subunit B', delta0.584
BMP2bone morphogenetic protein 20.582
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.579
FGF1fibroblast growth factor 1 (acidic)0.538
GSK3Bglycogen synthase kinase 3 beta0.526
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.502
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.500
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.500
IRF2BP1interferon regulatory factor 2 binding protein 10.487
FASLGFas ligand (TNF superfamily, member 6)0.475
HTThuntingtin0.475
PACSIN2protein kinase C and casein kinase substrate in neurons 20.472
SH2D4ASH2 domain containing 4A0.453
CFL1cofilin 1 (non-muscle)0.451
SCN5Asodium channel, voltage-gated, type V, alpha subunit0.444
CLASP1cytoplasmic linker associated protein 10.443
PRKCZprotein kinase C, zeta0.440
CUL1cullin 10.440
TSC1tuberous sclerosis 10.438
VAV1vav 1 guanine nucleotide exchange factor0.422
DUSP1dual specificity phosphatase 10.419
DCUN1D1DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)0.418
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.415
CYFIP2cytoplasmic FMR1 interacting protein 20.413
MBNL1muscleblind-like (Drosophila)0.412
AXIN1axin 10.409
SYKspleen tyrosine kinase0.403
LRRK2leucine-rich repeat kinase 20.403
MAP4K3mitogen-activated protein kinase kinase kinase kinase 30.403
COX17COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)0.388
FOSL1FOS-like antigen 10.388
SOS1son of sevenless homolog 1 (Drosophila)0.388
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.380
EPS8epidermal growth factor receptor pathway substrate 80.379
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.373
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.367
JUNDjun D proto-oncogene0.363
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.357
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.353
JUNBjun B proto-oncogene0.351
IQGAP1IQ motif containing GTPase activating protein 10.350
FUSfused in sarcoma0.349
MPRIPmyosin phosphatase Rho interacting protein0.349
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.349
PACSIN3protein kinase C and casein kinase substrate in neurons 30.346
RHOCras homolog gene family, member C0.344
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.344
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.342
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.340
MTMR12myotubularin related protein 120.335
SMURF1SMAD specific E3 ubiquitin protein ligase 10.334
SEPT2septin 20.334
MATKmegakaryocyte-associated tyrosine kinase0.334
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.331
MAP3K7mitogen-activated protein kinase kinase kinase 70.329
BMI1BMI1 polycomb ring finger oncogene0.324
GAS7growth arrest-specific 70.323
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.320
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.316
FGF10fibroblast growth factor 100.313
SH3RF1SH3 domain containing ring finger 10.305
ADAM17ADAM metallopeptidase domain 170.297
GDF5growth differentiation factor 50.292
PGRprogesterone receptor0.290
MAPTmicrotubule-associated protein tau0.284
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
spc-1Protein SPC-10.140
chd-7Protein CHD-70.111
ace-1Protein ACE-10.104
ace-3Protein ACE-30.101
mig-15Protein MIG-150.098
aha-1Protein AHA-10.094
eat-4Protein EAT-40.093
unc-9Protein UNC-90.091
R90.1Protein R90.10.087
dbl-1Protein DBL-10.086
clk-2Protein CLK-20.079
ncam-1Protein NCAM-10.078
tag-241Protein TAG-2410.078
plc-3Protein PLC-30.076
egl-15Protein EGL-150.073
dpy-22Protein DPY-220.071
hlh-30Protein HLH-300.069
sma-6Protein SMA-60.064
unc-54Protein UNC-540.064
pde-4Protein PDE-40.061
abts-1Protein ABTS-10.061
cdc-42Protein CDC-420.060
egl-8Protein EGL-80.060
ifg-1Protein IFG-10.056
hgrs-1Protein HGRS-10.056
unc-32Protein UNC-320.055
spk-1Protein SPK-10.054
lrp-2Protein LRP-20.053
syg-1Protein SYG-10.052
ace-2Protein ACE-20.052
cap-1Protein CAP-10.051
unc-89Protein UNC-890.050
kin-4Protein KIN-40.049
C05D11.9Protein C05D11.90.049
C17H11.6Protein C17H11.60.049
tbc-9Protein TBC-90.049
miz-1Protein MIZ-10.048
daf-3Protein DAF-30.047
gpb-1Protein GPB-10.047
hmg-1.2Protein HMG-1.20.047
clh-5Protein CLH-50.047
C11E4.6Protein C11E4.60.046
gsp-1Protein GSP-10.046
somi-1Protein SOMI-10.045
him-6Protein HIM-60.045
abl-1Protein ABL-10.045
pry-1Protein PRY-10.045
syd-1Protein SYD-10.045
egl-44Protein EGL-440.045
clp-1Protein CLP-10.045
ptp-3Protein PTP-30.045
dig-1Protein DIG-10.045
paa-1Protein PAA-10.045
ace-4Protein ACE-40.044
crm-1Protein CRM-10.043
C02F5.7Protein C02F5.70.043
lmn-1Protein LMN-10.042
lntl-1Protein LNTL-10.042
myo-6Protein MYO-60.042
nra-1Protein NRA-10.042
nhr-1Protein NHR-10.042
ina-1Protein INA-10.041
R13A5.9Protein R13A5.90.041
Y40C5A.1Protein Y40C5A.10.041
tbc-3Protein TBC-30.041
ced-10Protein CED-100.041
Y42G9A.3Protein Y42G9A.30.040
apb-1Protein APB-10.040
CELE_T04H1.2Protein T04H1.20.040
CELE_F21E9.2Protein F21E9.20.040
ZK484.1Protein ZK484.10.039
dlk-1Protein DLK-10.039
C06G3.6Protein C06G3.60.039
W03G9.3Protein W03G9.30.038
vav-1Protein VAV-10.038
gei-18Protein GEI-180.038
lam-2Protein LAM-20.038
ags-3Protein AGS-30.038
mig-5Protein MIG-50.038
tyr-1Protein TYR-10.038
F49E8.7Protein F49E8.70.038
F25B5.5Protein F25B5.50.038
daf-2Protein DAF-20.037
T08G11.1Protein T08G11.10.037
apa-2Protein APA-20.037
spe-39Protein SPE-390.037
madd-4Protein MADD-40.037
dnj-27Protein DNJ-270.036
dph-2Protein DPH-20.036
max-1Protein MAX-10.036
rskn-1Protein RSKN-10.036
Y54G2A.26Protein Y54G2A.260.036
let-19Protein LET-190.035
C47D12.2Protein C47D12.20.035
dep-1Protein DEP-10.035
abcf-2Protein ABCF-20.035
toca-1Protein TOCA-10.035
let-607Protein LET-6070.035
atg-11Protein ATG-110.035
F21A10.2Protein F21A10.20.035
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
trim33tripartite motif-containing 330.255
nf1aneurofibromin 1a0.095
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.086
scn8aasodium channel, voltage-gated, type VIII, alpha a0.062
lama2laminin, alpha 20.060
hapln3hyaluronan and proteoglycan link protein 30.056
spna2spectrin alpha 20.049
smosmoothened homolog (Drosophila)0.048
smad1MAD homolog 1 (Drosophila)0.047
bmp2bbone morphogenetic protein 2b0.042
junbjun B proto-oncogene0.041
atp6v0cbATPase, H+ transporting, lysosomal, V0 subunit c, b0.040
nlgn2bneuroligin 2b0.040
sh3gl1bSH3-domain GRB2-like 1b0.038
myo6bmyosin VIb0.037
extl3exostoses (multiple)-like 30.034
s1pr2sphingosine-1-phosphate receptor 20.033
ywhag13-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 10.031
psen1presenilin 10.029
dlg2discs, large (Drosophila) homolog 20.027
stmn2bstathmin-like 2b0.025
bmpr2bbone morphogenetic protein receptor, type II b (serine/threonine kinase)0.025
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.025
dmddystrophin0.025
bocbrother of CDO0.024
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.024
cdkl1cyclin-dependent kinase-like 1 (CDC2-related kinase)0.024
bmpr2abone morphogenetic protein receptor, type II a (serine/threonine kinase)0.024
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.023
atp1b3aATPase, Na+/K+ transporting, beta 3a polypeptide0.023
ptpraprotein tyrosine phosphatase, receptor type, A0.022
ndrg4N-myc downstream regulated gene 40.022
lrrc50leucine rich repeat containing 500.022
atp1a3aATPase, Na+/K+ transporting, alpha 3a polypeptide0.022
chrndcholinergic receptor, nicotinic, delta polypeptide0.020
pvrl1bpoliovirus receptor-related 1b0.020
arnt2aryl hydrocarbon receptor nuclear translocator 20.020
aldocbaldolase C, fructose-bisphosphate, b0.018
ela3lelastase 3 like0.018
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.018
dag1dystroglycan 10.018
sept6septin 60.017
slc1a2bsolute carrier family 1 (glial high affinity glutamate transporter), member 2b0.016
LOC100535672trypsin-1-like0.016
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.016
junbljun B proto-oncogene, like0.016
gng3guanine nucleotide binding protein (G protein), gamma 30.016
rtn1areticulon 1a0.016
atf3activating transcription factor 30.015
gpr126G protein-coupled receptor 1260.015
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.015
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.015
tuba1ltubulin, alpha 1, like0.015
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 60.014
mfn2mitofusin 20.014
myf6myogenic factor 60.014
sncbsynuclein, beta0.014
ntrk2aneurotrophic tyrosine kinase, receptor, type 2a0.013
acvr1lactivin A receptor, type I like0.013
myd88myeloid differentiation primary response gene (88)0.013
rcn1reticulocalbin 1, EF-hand calcium binding domain0.013
meis4.1amyeloid ecotropic viral integration site 4.1a0.013
egr1early growth response 10.013
gap43growth associated protein 430.013
bcl2l1bcl2-like 10.012
sulf2sulfatase 20.012
alcambactivated leukocyte cell adhesion molecule b0.012
socs3asuppressor of cytokine signaling 3a0.012
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.012
trpa1btransient receptor potential cation channel, subfamily A, member 1b0.012
nadl1.2neural adhesion molecule L1.20.012
thsd7athrombospondin, type I, domain containing 7A0.012
snap25asynaptosome-associated protein 25a0.012
igfbp3insulin-like growth factor binding protein 30.012
gad1bglutamate decarboxylase 1b0.012
foxn4forkhead box N40.012
pdlim3bPDZ and LIM domain 3b0.011
rac3aras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3)0.011
pdia5protein disulfide isomerase family A, member 50.011
npc1Niemann-Pick disease, type C10.011
mef2dmyocyte enhancer factor 2d0.011
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.011
plxnb2aplexin b2a0.011
si:dkey-202c5.1si:dkey-202c5.10.011
adcyap1badenylate cyclase activating polypeptide 1b0.011
gsnagelsolin a0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Cip4CG15015 gene product from transcript CG15015-RA1.000
CaMKIICalcium/calmodulin-dependent protein kinase II1.000
MadMothers against dpp1.000
witwishful thinking0.999
TBPHCG10327 gene product from transcript CG10327-RC0.999
Ank2Ankyrin 20.999
brpbruchpilot0.999
G-oalpha47AG protein oalpha 47A0.998
nwknervous wreck0.998
Dap160Dynamin associated protein 1600.998
CspCysteine string protein0.998
trioCG18214 gene product from transcript CG18214-RA0.997
enaenabled0.995
Vap-33-1CG5014 gene product from transcript CG5014-RB0.994
WASpCG1520 gene product from transcript CG1520-RA0.994
neuroliginCG13772 gene product from transcript CG13772-RA0.994
stnBstoned B0.992
Mob2CG11711 gene product from transcript CG11711-RC0.990
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.989
beta-Specbeta Spectrin0.987
Fak56DFocal Adhesion Kinase0.983
RhoGAP92BCG4755 gene product from transcript CG4755-RA0.976
dlpdally-like0.976
Pi3K92ECG4141 gene product from transcript CG4141-RB0.975
NetBNetrin-B0.975
Syx1ASyntaxin 1A0.975
AcslAcyl-CoA synthetase long-chain0.973
par-1CG8201 gene product from transcript CG8201-RA0.968
cazcabeza0.965
Fmr1CG6203 gene product from transcript CG6203-RC0.960
Snap25Synapse protein 250.956
cpxcomplexin0.953
CG31146CG31146 gene product from transcript CG31146-RD0.953
dncdunce0.949
mlemaleless0.943
Atg1Autophagy-specific gene 10.942
Hip14Huntingtin-interacting protein 140.942
spasspastin0.941
DadDaughters against dpp0.934
oa2octopamine receptor 20.933
synaptogyrinCG10808 gene product from transcript CG10808-RA0.933
Akt1CG4006 gene product from transcript CG4006-RA0.932
Nrx-1Neurexin 10.931
Frq1Frequenin 10.928
ik2IkappaB kinase-like 20.923
LrrkLeucine-rich repeat kinase0.922
PakPAK-kinase0.922
ecdecdysoneless0.918
jebjelly belly0.918
rutrutabaga0.916
GluRIIAGlutamate receptor IIA0.911
NrgNeuroglian0.901
Octbeta2RCG33976 gene product from transcript CG33976-RA0.900
faffat facets0.898
CG18005CG18005 gene product from transcript CG18005-RA0.896
CG10083CG10083 gene product from transcript CG10083-RA0.895
PtenCG5671 gene product from transcript CG5671-RB0.894
Eps-15Epidermal growth factor receptor pathway substrate clone 150.880
cpbcapping protein beta0.873
Syt1Synaptotagmin 10.870
elavembryonic lethal abnormal vision0.864
fz2frizzled 20.858
AlkCG8250 gene product from transcript CG8250-RA0.847
tomosynCG17762 gene product from transcript CG17762-RB0.833
CrebB-17ACyclic-AMP response element binding protein B at 17A0.816
AblAbl tyrosine kinase0.816
NFATNFAT homolog0.814
mnbminibrain0.812
unc-104CG8566 gene product from transcript CG8566-RB0.809
Ca-alpha1DCa[2+]-channel protein alpha[[1]] subunit D0.806
Act57BActin 57B0.801
myoglianinCG1838 gene product from transcript CG1838-RD0.799
FsnCG4643 gene product from transcript CG4643-RA0.795
CG9339CG9339 gene product from transcript CG9339-RG0.794
cdmcadmus0.780
comtcomatose0.774
hiwhighwire0.773
sinaseven in absentia0.773
bskbasket0.771
stepsteppke0.751
CCKLR-17D1CCK-like receptor at 17D10.743
TbhTyramine beta hydroxylase0.742
Letm1CG4589 gene product from transcript CG4589-RB0.741
bratbrain tumor0.738
BicDBicaudal D0.732
Rac1CG2248 gene product from transcript CG2248-RA0.731
AmphAmphiphysin0.727
LanALaminin A0.724
RanBPMRan-binding protein M0.717
wndwallenda0.717
Rab5Rab-protein 50.712
gbbglass bottom boat0.711
Cdc42CG12530 gene product from transcript CG12530-RA0.711
scbscab0.711
Sra-1specifically Rac1-associated protein 10.710
alpha-Specalpha Spectrin0.708
pumpumilio0.680
Syt4Synaptotagmin 40.679
katanin-60katanin 600.670
weeCG4488 gene product from transcript CG4488-RA0.658
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.042
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.027
Sirpasignal-regulatory protein alpha0.021
Nrxn1neurexin 10.015
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.013
Atf3activating transcription factor 30.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism