The network for 'myoblast fusion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myoblast fusion

A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.

NameDescriptionProbabilityFunc Analog Organism
GRB2growth factor receptor-bound protein 20.999
CREBBPCREB binding protein0.986
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.901
EGFRepidermal growth factor receptor0.891
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.855
PGK1phosphoglycerate kinase 10.814
IL4Rinterleukin 4 receptor0.792
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.749
ALDOAaldolase A, fructose-bisphosphate0.747
PTK2PTK2 protein tyrosine kinase 20.740
LIMS1LIM and senescent cell antigen-like domains 10.738
CASP8caspase 8, apoptosis-related cysteine peptidase0.665
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.632
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.624
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.612
IQGAP1IQ motif containing GTPase activating protein 10.594
ARandrogen receptor0.570
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.569
NCOA3nuclear receptor coactivator 30.557
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.528
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.516
SRFserum response factor (c-fos serum response element-binding transcription factor)0.436
KAT2BK(lysine) acetyltransferase 2B0.435
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.433
PGAM1phosphoglycerate mutase 1 (brain)0.427
LDHAlactate dehydrogenase A0.426
ACTBactin, beta0.419
MYL9myosin, light chain 9, regulatory0.413
DPP4dipeptidyl-peptidase 40.409
VAV1vav 1 guanine nucleotide exchange factor0.402
WIPF1WAS/WASL interacting protein family, member 10.398
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.391
GPIglucose-6-phosphate isomerase0.359
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.355
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.315
STK10serine/threonine kinase 100.315
SHC1SHC (Src homology 2 domain containing) transforming protein 10.314
LRRK2leucine-rich repeat kinase 20.306
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.305
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.305
ENO1enolase 1, (alpha)0.303
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.293
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.292
NLRC4NLR family, CARD domain containing 40.289
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.261
GRB10growth factor receptor-bound protein 100.249
IL2RGinterleukin 2 receptor, gamma0.240
CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.236
CXCL11chemokine (C-X-C motif) ligand 110.227
IRS1insulin receptor substrate 10.225
LZTS2leucine zipper, putative tumor suppressor 20.212
HIPK2homeodomain interacting protein kinase 20.205
AKT1v-akt murine thymoma viral oncogene homolog 10.203
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.201
SH3RF1SH3 domain containing ring finger 10.199
SH3KBP1SH3-domain kinase binding protein 10.199
HDAC4histone deacetylase 40.196
CASP10caspase 10, apoptosis-related cysteine peptidase0.195
BCAR1breast cancer anti-estrogen resistance 10.190
RPTORregulatory associated protein of MTOR, complex 10.190
NCK1NCK adaptor protein 10.185
GAB1GRB2-associated binding protein 10.184
IL4interleukin 40.179
COASYCoA synthase0.179
NCOA6nuclear receptor coactivator 60.176
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.158
HCKhemopoietic cell kinase0.158
TNFSF10tumor necrosis factor (ligand) superfamily, member 100.151
MAP2K3mitogen-activated protein kinase kinase 30.149
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.145
EP300E1A binding protein p3000.144
MED31mediator complex subunit 310.139
ARPC1Bactin related protein 2/3 complex, subunit 1B, 41kDa0.135
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.132
SIRT1sirtuin 10.130
IRS2insulin receptor substrate 20.128
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.127
RICTORRPTOR independent companion of MTOR, complex 20.124
ANKFY1ankyrin repeat and FYVE domain containing 10.124
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.120
CREB1cAMP responsive element binding protein 10.119
CASP4caspase 4, apoptosis-related cysteine peptidase0.119
NCF2neutrophil cytosolic factor 20.118
SPECC1Lsperm antigen with calponin homology and coiled-coil domains 1-like0.118
FLNAfilamin A, alpha0.115
RUNX1runt-related transcription factor 10.111
TNS1tensin 10.111
TPI1triosephosphate isomerase 10.101
HDAC9histone deacetylase 90.101
INSRinsulin receptor0.100
ABI2abl-interactor 20.098
FOXO3forkhead box O30.094
SMAD3SMAD family member 30.092
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.091
JAM3junctional adhesion molecule 30.090
NCOA1nuclear receptor coactivator 10.089
HOXA1homeobox A10.087
TCF4transcription factor 40.086
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
myod1myogenic differentiation 10.918
mef2camyocyte enhancer factor 2ca0.844
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.811
mef2dmyocyte enhancer factor 2d0.679
jam2ajunctional adhesion molecule 2a0.436
tpm4tropomyosin 40.370
gmfgglia maturation factor, gamma0.206
kirrel3lkin of IRRE like 3 like0.199
jam3bjunctional adhesion molecule 3b0.198
dock1dedicator of cytokinesis 10.167
wt1bwilms tumor 1b0.165
desmadesmin a0.153
metmet proto-oncogene (hepatocyte growth factor receptor)0.146
vegfabvascular endothelial growth factor Ab0.138
meox1mesenchyme homeobox 10.131
akt2v-akt murine thymoma viral oncogene homolog 20.124
dccdeleted in colorectal carcinoma0.116
wt1awilms tumor 1a0.113
gata6GATA-binding protein 60.109
ldb2aLIM-domain binding factor 2a0.107
colec11collectin sub-family member 110.100
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.099
lsrlipolysis stimulated lipoprotein receptor0.097
mef2amyocyte enhancer factor 2a0.096
zbtb4zinc finger and BTB domain containing 40.094
glcci1glucocorticoid induced transcript 10.093
myf5myogenic factor 50.091
rapsnreceptor-associated protein of the synapse, 43kD0.090
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.085
etv2ets variant gene 20.083
vmhcventricular myosin heavy chain0.082
smyd1bSET and MYND domain containing 1b0.077
hsp90a.1heat shock protein 90-alpha 10.068
dock5dedicator of cytokinesis 50.066
cyt1type I cytokeratin, enveloping layer0.063
vdravitamin D receptor a0.060
cdh1cadherin 1, epithelial0.056
myf6myogenic factor 60.055
mmp9matrix metalloproteinase 90.053
caspacaspase a0.052
adipor1badiponectin receptor 1b0.052
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.050
frmd6FERM domain containing 60.047
pkm2apyruvate kinase, muscle, a0.046
ldb1aLIM-domain binding factor 1a0.045
foxn1forkhead box N10.044
vegfaavascular endothelial growth factor Aa0.044
ldb3aLIM-domain binding factor 3a0.043
osr1odd-skipped related 1 (Drosophila)0.042
wtipWilms tumor 1 interacting protein0.042
tcf12transcription factor 120.042
dhrs3adehydrogenase/reductase (SDR family) member 3a0.042
unc5cunc-5 homolog C (C. elegans)0.039
ctnnacatenin (cadherin-associated protein), alpha0.039
vgll2bvestigial like 2b0.038
unc45bunc-45 homolog B (C. elegans)0.038
coro1acoronin, actin binding protein, 1A0.038
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.037
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.035
LOC566969similar to MOX-2 protein0.034
mpllmyeloproliferative leukemia virus oncogene, like0.034
flncbfilamin C, gamma b (actin binding protein 280)0.033
irx5airoquois homeobox protein 5a0.032
mybpc2bmyosin binding protein C, fast type b0.031
bmp2kBMP2 inducible kinase0.031
hoxa9bhomeo box A9b0.030
hoxb5ahomeo box B5a0.029
restRE1-silencing transcription factor0.028
mycamyelocytomatosis oncogene a0.027
sh3gl1bSH3-domain GRB2-like 1b0.026
crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.026
gpiaglucose phosphate isomerase a0.026
sept2septin 20.026
vax2ventral anterior homeobox 20.025
atp1a2aATPase, Na+/K+ transporting, alpha 2a polypeptide0.025
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.025
plce1phospholipase C, epsilon 10.025
arhgef1rho guanine nucleotide exchange factor (GEF) 10.025
emp2epithelial membrane protein 20.024
sema3fasemaphorin 3fa0.023
LOC557722similar to transient receptor potential cation channel, subfamily M, member 50.023
llgl2lethal giant larvae homolog 2 (Drosophila)0.023
nr1h5nuclear receptor subfamily 1, group H, member 50.023
pgm1phosphoglucomutase 10.022
ryr1bryanodine receptor 1b (skeletal)0.022
myhc4myosin heavy chain 40.022
tnfsf18tumor necrosis factor (ligand) superfamily, member 180.022
eno3enolase 3, (beta, muscle)0.021
pabpc4poly(A) binding protein, cytoplasmic 4 (inducible form)0.021
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Vrp1Verprolin 11.000
snssticks and stones1.000
rolsrolling pebbles1.000
mbcmyoblast city0.999
Rac2CG8556 gene product from transcript CG8556-RA0.999
Arf51FADP ribosylation factor 51F0.998
blowblown fuse0.998
Mp20Muscle protein 200.992
S6kRPS6-p70-protein kinase0.989
TpiTriose phosphate isomerase0.988
WASpCG1520 gene product from transcript CG1520-RA0.986
PyKPyruvate kinase0.985
kirrekin of irre0.982
Rac1CG2248 gene product from transcript CG2248-RA0.977
Mef2Myocyte enhancer factor 20.976
ThorCG8846 gene product from transcript CG8846-RA0.958
Arf79FADP ribosylation factor 79F0.933
mib2mind bomb 20.863
foxoforkhead box, sub-group O0.845
Rho1CG8416 gene product from transcript CG8416-RB0.825
lbeladybird early0.811
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.797
AlkCG8250 gene product from transcript CG8250-RA0.780
singsingles bar0.774
lmdlame duck0.765
Mlp84BMuscle LIM protein at 84B0.749
ImpL3Ecdysone-inducible gene L30.743
vavCG7893 gene product from transcript CG7893-RB0.740
aopanterior open0.720
zfh1Zn finger homeodomain 10.682
Arp66BActin-related protein 66B0.673
p120ctnAdherens junction protein p1200.626
LamCLamin C0.620
RalaRas-related protein0.554
bibbig brain0.488
InRInsulin-like receptor0.403
ParpPoly-(ADP-ribose) polymerase0.387
AbiAbelson interacting protein0.340
GripGlutamate receptor binding protein0.288
PgkPhosphoglycerate kinase0.282
Sra-1specifically Rac1-associated protein 10.263
Pak3CG14895 gene product from transcript CG14895-RA0.253
HimHoles in muscle0.234
imdimmune deficiency0.225
Akt1CG4006 gene product from transcript CG4006-RA0.220
Kr-h1Kruppel homolog 10.169
eyaeyes absent0.148
C3GCG42328 gene product from transcript CG42328-RC0.136
Ras85DRas oncogene at 85D0.135
CG1021CG1021 gene product from transcript CG1021-RE0.124
RanBPMRan-binding protein M0.123
drkdownstream of receptor kinase0.121
Gs1Glutamine synthetase 10.114
Atg1Autophagy-specific gene 10.105
LrtLeucine-rich tendon-specific protein0.095
vimarvisceral mesodermal armadillo-repeats0.093
Taf4TBP-associated factor 40.091
jebjelly belly0.086
Myd88CG2078 gene product from transcript CG2078-RA0.084
X11LCG5675 gene product from transcript CG5675-RB0.083
Vap-33-1CG5014 gene product from transcript CG5014-RB0.082
CG32528CG32528 gene product from transcript CG32528-RA0.076
eveeven skipped0.065
Gyc76CGuanylyl cyclase at 76C0.059
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Casp1caspase 10.060
Emp1epithelial membrane protein 10.043
Pgk1phosphoglycerate kinase 10.040
Syngr2synaptogyrin 20.037
Ptbp1polypyrimidine tract binding protein 10.036
Myo1bmyosin Ib0.033
Tpm4tropomyosin 40.033
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.030
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.030
Lbrlamin B receptor0.028
Tcf12transcription factor 120.028
Myo1cmyosin IC0.025
Ptprcprotein tyrosine phosphatase, receptor type, C0.025
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.025
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.024
Tgfbr2transforming growth factor, beta receptor II0.024
Smad1SMAD family member 10.024
Il5interleukin 50.023
Ms4a11membrane-spanning 4-domains, subfamily A, member 110.022
Skap2src kinase associated phosphoprotein 20.021
Tpi1triosephosphate isomerase 10.020
Txnrd1thioredoxin reductase 10.020
Arl5aADP-ribosylation factor-like 5A0.020
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.019
Ccnd3cyclin D30.019
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.019
Mdh1malate dehydrogenase 1, NAD (soluble)0.019
Myh9myosin, heavy chain 9, non-muscle0.019
Cxcl9chemokine (C-X-C motif) ligand 90.019
Cald1caldesmon 10.018
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.018
Acvr1activin A receptor, type I0.017
Flnbfilamin, beta0.017
Eef2eukaryotic translation elongation factor 20.017
Cdk2cyclin dependent kinase 20.017
Lamc1laminin, gamma 10.017
Adam10ADAM metallopeptidase domain 100.017
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.017
Actn4actinin alpha 40.017
Col4a1collagen, type IV, alpha 10.017
Irs1insulin receptor substrate 10.016
Nat1N-acetyltransferase 10.016
Adam17ADAM metallopeptidase domain 170.016
Clic4chloride intracellular channel 40.016
Arf6ADP-ribosylation factor 60.016
Stk17bserine/threonine kinase 17b0.016
Scarb1scavenger receptor class B, member 10.016
Lin7clin-7 homolog C (C. elegans)0.016
S1pr2sphingosine-1-phosphate receptor 20.015
Galnt1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)0.015
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.015
Cpa1carboxypeptidase A10.015
Shisa5shisa homolog 5 (Xenopus laevis)0.015
Itga6integrin, alpha 60.015
Fusip1FUS interacting protein (serine-arginine rich) 10.015
Id2inhibitor of DNA binding 20.015
Ccl20chemokine (C-C motif) ligand 200.015
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.015
Dnajc14DnaJ (Hsp40) homolog, subfamily C, member 140.015
Itgalintegrin, alpha L0.015
Efhd2EF-hand domain family, member D20.015
Itgb2integrin, beta 20.014
Iqgap1IQ motif containing GTPase activating protein 10.014
Prkchprotein kinase C, eta0.014
Hbg1hemoglobin, gamma A0.014
Cngb1cyclic nucleotide gated channel beta 10.014
Stat6signal transducer and activator of transcription 60.014
Cd48Cd48 molecule0.014
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.014
Casp8caspase 80.014
Cd38CD38 molecule0.013
Mpripmyosin phosphatase Rho interacting protein0.013
Anxa1annexin A10.013
Glipr1GLI pathogenesis-related 10.013
Nek9NIMA (never in mitosis gene a)- related kinase 90.013
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.013
Fam198bfamily with sequence similarity 198, member B0.013
Cav3caveolin 30.013
Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.013
Jak2Janus kinase 20.013
Mylpfmyosin light chain, phosphorylatable, fast skeletal muscle0.013
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.013
Fbln5fibulin 50.013
Evi2aecotropic viral integration site 2A0.013
Cxcl11chemokine (C-X-C motif) ligand 110.013
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.013
Gbp2guanylate binding protein 20.013
Arhgap1Rho GTPase activating protein 10.013
AhnakAHNAK nucleoprotein0.013
Nrasneuroblastoma ras oncogene0.012
Smpxsmall muscle protein, X-linked0.012
Rhoaras homolog gene family, member A0.012
Myl1myosin, light chain 10.012
Lamb2laminin, beta 20.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism