The network for 'regulation of epithelial cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of epithelial cell migration

Any process that modulates the frequency, rate or extent of epithelial cell migration.

NameDescriptionProbabilityFunc Analog Organism
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
EGFRepidermal growth factor receptor1.000
FN1fibronectin 11.000
JAG1jagged 11.000
BCAR1breast cancer anti-estrogen resistance 10.999
FYNFYN oncogene related to SRC, FGR, YES0.999
VEGFAvascular endothelial growth factor A0.999
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.998
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.998
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.997
FGFR2fibroblast growth factor receptor 20.997
LCKlymphocyte-specific protein tyrosine kinase0.995
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.994
YAP1Yes-associated protein 10.994
NOTCH1notch 10.991
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.991
PTK2PTK2 protein tyrosine kinase 20.990
RARAretinoic acid receptor, alpha0.990
NRP1neuropilin 10.982
SYKspleen tyrosine kinase0.981
THBS1thrombospondin 10.972
TEKTEK tyrosine kinase, endothelial0.960
TGFB1transforming growth factor, beta 10.957
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.949
ENGendoglin0.942
LATlinker for activation of T cells0.939
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.937
FGFR1fibroblast growth factor receptor 10.937
CAV1caveolin 1, caveolae protein, 22kDa0.934
ACTBactin, beta0.933
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.927
SH3KBP1SH3-domain kinase binding protein 10.906
SKILSKI-like oncogene0.906
TAL1T-cell acute lymphocytic leukemia 10.904
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.896
PDCD6IPprogrammed cell death 6 interacting protein0.889
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.880
TIMP1TIMP metallopeptidase inhibitor 10.875
SMAD7SMAD family member 70.853
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.807
NOTCH3notch 30.804
PTPN1protein tyrosine phosphatase, non-receptor type 10.792
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.766
DLG1discs, large homolog 1 (Drosophila)0.758
GRB2growth factor receptor-bound protein 20.753
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.751
FKBP1AFK506 binding protein 1A, 12kDa0.751
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.738
ADAM15ADAM metallopeptidase domain 150.730
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.727
NCOR2nuclear receptor corepressor 20.715
SMAD3SMAD family member 30.710
DUSP1dual specificity phosphatase 10.709
BAG3BCL2-associated athanogene 30.695
PAX3paired box 30.684
SMN1survival of motor neuron 1, telomeric0.683
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.680
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.674
FLNAfilamin A, alpha0.667
ZYXzyxin0.650
FSTL1follistatin-like 10.640
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.622
PTK2BPTK2B protein tyrosine kinase 2 beta0.610
AMOTL1angiomotin like 10.608
GRB7growth factor receptor-bound protein 70.602
HDAC7histone deacetylase 70.595
FGF1fibroblast growth factor 1 (acidic)0.593
CYR61cysteine-rich, angiogenic inducer, 610.581
A2Malpha-2-macroglobulin0.572
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.567
PLCG1phospholipase C, gamma 10.558
SPTBN1spectrin, beta, non-erythrocytic 10.552
PRKCAprotein kinase C, alpha0.549
TIMP3TIMP metallopeptidase inhibitor 30.531
VEGFCvascular endothelial growth factor C0.524
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.523
TSC22D1TSC22 domain family, member 10.521
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.519
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.519
SPRR2Asmall proline-rich protein 2A0.514
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.509
CRYABcrystallin, alpha B0.508
SHC1SHC (Src homology 2 domain containing) transforming protein 10.481
VAV1vav 1 guanine nucleotide exchange factor0.472
NCOR1nuclear receptor corepressor 10.470
BMPR1Abone morphogenetic protein receptor, type IA0.468
COL5A1collagen, type V, alpha 10.466
MAPK1mitogen-activated protein kinase 10.455
HSPB8heat shock 22kDa protein 80.445
ITGB5integrin, beta 50.425
NCF1neutrophil cytosolic factor 10.423
PPLperiplakin0.423
BCL6B-cell CLL/lymphoma 60.422
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.420
POU5F1POU class 5 homeobox 10.412
PDGFCplatelet derived growth factor C0.409
WWP2WW domain containing E3 ubiquitin protein ligase 20.409
FGAfibrinogen alpha chain0.407
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.405
MED25mediator complex subunit 250.398
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp2bbone morphogenetic protein 2b0.328
vegfcvascular endothelial growth factor c0.096
notch3notch homolog 30.089
sox9aSRY-box containing gene 9a0.079
nrarpanotch-regulated ankyrin repeat protein a0.078
ilkintegrin linked kinase0.077
dlcdeltaC0.067
ccm2cerebral cavernous malformation 20.061
plcg1phospholipase C, gamma 10.052
dlx5adistal-less homeobox gene 5a0.050
efnb2aephrin B2a0.047
antxr1anthrax toxin receptor 10.044
alcambactivated leukocyte cell adhesion molecule b0.041
sulf1sulfatase 10.041
si:ch211-212m21.5si:ch211-212m21.50.040
dll4delta-like 4 (Drosophila)0.039
prrx1apaired related homeobox 1a0.035
tpm4tropomyosin 40.035
flt4fms-related tyrosine kinase 40.035
vaspvasodilator-stimulated phosphoprotein0.033
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.032
mmp2matrix metalloproteinase 20.031
gli2aGLI-Kruppel family member GLI2a0.029
dlddeltaD0.028
trpm7transient receptor potential cation channel, subfamily M, member 70.028
ptgs1prostaglandin-endoperoxide synthase 10.028
xirp2axin actin-binding repeat containing 2a0.027
lama2laminin, alpha 20.027
sgk1serum/glucocorticoid regulated kinase 10.027
ascl1aachaete-scute complex-like 1a (Drosophila)0.027
dladeltaA0.026
etv2ets variant gene 20.026
LOC100003514protein kinase C alpha type-like0.025
bmpr2abone morphogenetic protein receptor, type II a (serine/threonine kinase)0.025
crb2acrumbs homolog 2a0.024
pitx3paired-like homeodomain transcription factor 30.024
unc5bunc-5 homolog B (C. elegans)0.024
neurodneurogenic differentiation0.022
vegfaavascular endothelial growth factor Aa0.022
lyzlysozyme0.020
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.020
mef2camyocyte enhancer factor 2ca0.018
ntn1anetrin 1a0.018
prkciprotein kinase C, iota0.016
krit1KRIT1, ankyrin repeat containing0.016
myhz2myosin, heavy polypeptide 2, fast muscle specific0.016
fabp11afatty acid binding protein 11a0.016
lmx1b.1LIM homeobox transcription factor 1, beta 10.015
si:rp71-39b20.7si:rp71-39b20.70.015
plxnb2aplexin b2a0.014
hey1hairy/enhancer-of-split related with YRPW motif 10.014
dbx1adeveloping brain homeobox 1a0.014
bmp4bone morphogenetic protein 40.014
alcamaactivated leukocyte cell adhesion molecule a0.014
dlbdeltaB0.014
ptrfbpolymerase I and transcript release factor b0.014
rrasrelated RAS viral (r-ras) oncogene homolog0.014
tbx18T-box 180.014
nrarpbnotch-regulated ankyrin repeat protein b0.014
gsnagelsolin a0.013
mmp9matrix metalloproteinase 90.013
fgf20afibroblast growth factor 20a0.013
slit2slit (Drosophila) homolog 20.013
ahr2aryl hydrocarbon receptor 20.013
slit3slit (Drosophila) homolog 30.013
sox19aSRY-box containing gene 19a0.013
shhasonic hedgehog a0.013
skianuclear oncoprotein skia0.013
tjp2atight junction protein 2a (zona occludens 2)0.012
coro2acoronin, actin binding protein, 2A0.012
trpv6transient receptor potential cation channel, subfamily V, member 60.012
wtipWilms tumor 1 interacting protein0.012
lamc1laminin, gamma 10.012
myod1myogenic differentiation 10.012
tcf7transcription factor 7 (T-cell specific, HMG-box)0.012
ptch2patched 20.011
pxnpaxillin0.011
kdelr3KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 30.011
hsp47heat shock protein 470.011
ptgs2aprostaglandin-endoperoxide synthase 2a0.011
lama1laminin, alpha 10.011
slc6a8solute carrier family 6 (neurotransmitter transporter, creatine), member 80.011
tie1endothelium-specific receptor tyrosine kinase 10.011
junjun proto-oncogene0.010
myogmyogenin0.010
edn1endothelin 10.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
lealeak0.884
mbcmyoblast city0.861
trioCG18214 gene product from transcript CG18214-RA0.846
roboroundabout0.785
aopanterior open0.760
spispitz0.724
EgfrEpidermal growth factor receptor0.532
Stat92ESignal-transducer and activator of transcription protein at 92E0.428
HemHEM-protein0.414
NNotch0.375
drkdownstream of receptor kinase0.321
tkvthickveins0.321
hhhedgehog0.320
putpunt0.308
wgwingless0.291
frafrazzled0.234
LanALaminin A0.229
sevsevenless0.224
pntpointed0.223
hthhomothorax0.222
cnkconnector enhancer of ksr0.206
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.205
rhorhomboid0.200
drlderailed0.182
eyaeyes absent0.172
hipkhomeodomain interacting protein kinase0.170
InRInsulin-like receptor0.166
bnlbranchless0.143
ifinflated0.142
NrgNeuroglian0.139
ttktramtrack0.134
scbscab0.126
slislit0.118
hpohippo0.118
stumpsCG31317 gene product from transcript CG31317-RC0.113
Ced-12CG5336 gene product from transcript CG5336-RA0.109
babobaboon0.098
Rac1CG2248 gene product from transcript CG2248-RA0.097
cicubitus interruptus0.095
zfh1Zn finger homeodomain 10.093
Nrx-IVNeurexin IV0.085
AblAbl tyrosine kinase0.085
MadMothers against dpp0.082
stysprouty0.081
spensplit ends0.080
eebony0.079
htlheartless0.079
unc-104CG8566 gene product from transcript CG8566-RB0.078
ttan0.076
NetBNetrin-B0.069
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.068
tutlturtle0.068
Pi3K92ECG4141 gene product from transcript CG4141-RB0.068
chicoCG5686 gene product from transcript CG5686-RB0.061
TlToll0.061
dosdaughter of sevenless0.060
Rab5Rab-protein 50.056
btlbreathless0.056
Sema-1aCG18405 gene product from transcript CG18405-RD0.056
srstripe0.053
ttvtout-velu0.052
SmoxSmad on X0.051
Rab7Rab-protein 70.051
Sra-1specifically Rac1-associated protein 10.050
sosine oculis0.049
staistathmin0.049
srpserpent0.047
stanstarry night0.046
panpangolin0.046
sglsugarless0.043
klgklingon0.043
kuzkuzbanian0.042
shishibire0.040
MrtfMyocardin-related transcription factor0.039
wunwunen0.038
CakiCalcium/calmodulin-dependent protein kinase0.038
mewmultiple edematous wings0.036
tgotango0.036
par-1CG8201 gene product from transcript CG8201-RA0.036
DadDaughters against dpp0.035
Mob2CG11711 gene product from transcript CG11711-RC0.035
plexAplexin A0.033
rtGEFrho-type guanine exchange factor0.032
laplike-AP1800.032
CapsCalcium activated protein for secretion0.031
ApcAPC-like0.031
mammastermind0.030
EcREcdysone receptor0.030
Wnt5Wnt oncogene analog 50.030
CycACyclin A0.030
NPFR1neuropeptide F receptor0.029
ushu-shaped0.029
dppdecapentaplegic0.028
G-oalpha47AG protein oalpha 47A0.028
numbCG3779 gene product from transcript CG3779-RB0.028
bazbazooka0.028
dacdachshund0.027
unc-5CG8166 gene product from transcript CG8166-RA0.027
tomosynCG17762 gene product from transcript CG17762-RB0.027
zetaTryzetaTrypsin0.026
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.970
Ptenphosphatase and tensin homolog0.929
Gli3GLI-Kruppel family member GLI30.923
Fgfr1fibroblast growth factor receptor 10.920
Ntf3neurotrophin 30.895
Ctnnb1catenin (cadherin associated protein), beta 10.854
Notch1Notch gene homolog 1 (Drosophila)0.843
Tgfb2transforming growth factor, beta 20.832
Efnb2ephrin B20.817
Vegfavascular endothelial growth factor A0.793
Cdh5cadherin 50.793
Ptpn11protein tyrosine phosphatase, non-receptor type 110.745
Pax2paired box gene 20.736
Bmp4bone morphogenetic protein 40.722
Ephb2Eph receptor B20.710
Ptprbprotein tyrosine phosphatase, receptor type, B0.678
Emx1empty spiracles homolog 1 (Drosophila)0.636
Pax8paired box gene 80.611
Kdrkinase insert domain protein receptor0.585
Foxc1forkhead box C10.544
Rargretinoic acid receptor, gamma0.537
Sox7SRY-box containing gene 70.527
Pax3paired box gene 30.526
Shhsonic hedgehog0.523
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.495
Robo1roundabout homolog 1 (Drosophila)0.490
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.485
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.485
Nos3nitric oxide synthase 3, endothelial cell0.424
Tgfbr2transforming growth factor, beta receptor II0.411
Eya1eyes absent 1 homolog (Drosophila)0.405
Apcadenomatosis polyposis coli0.394
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.380
Foxa2forkhead box A20.374
Epha4Eph receptor A40.372
Fgf10fibroblast growth factor 100.354
Fgf8fibroblast growth factor 80.353
SrcRous sarcoma oncogene0.340
Tgfatransforming growth factor alpha0.333
Hif1ahypoxia inducible factor 1, alpha subunit0.316
Pax6paired box gene 60.308
Jag2jagged 20.301
Acvr1activin A receptor, type 10.295
Gli2GLI-Kruppel family member GLI20.294
Jag1jagged 10.280
Sox18SRY-box containing gene 180.278
Col4a2collagen, type IV, alpha 20.278
Tcfap2atranscription factor AP-2, alpha0.275
Col4a1collagen, type IV, alpha 10.274
Gata4GATA binding protein 40.269
Prrx1paired related homeobox 10.264
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.262
Ednrbendothelin receptor type B0.261
Wnt4wingless-related MMTV integration site 40.259
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.259
Flt1FMS-like tyrosine kinase 10.256
Epas1endothelial PAS domain protein 10.248
Nkx2-1NK2 homeobox 10.236
Dll1delta-like 1 (Drosophila)0.235
Hand2heart and neural crest derivatives expressed transcript 20.231
Snai1snail homolog 1 (Drosophila)0.228
Cyr61cysteine rich protein 610.228
Wnt7awingless-related MMTV integration site 7A0.216
Flt4FMS-like tyrosine kinase 40.211
Egfrepidermal growth factor receptor0.211
Gata6GATA binding protein 60.194
Smosmoothened homolog (Drosophila)0.193
Mmp15matrix metallopeptidase 150.192
Ror1receptor tyrosine kinase-like orphan receptor 10.192
Nr2f2nuclear receptor subfamily 2, group F, member 20.189
Shesrc homology 2 domain-containing transforming protein E0.187
Smad3MAD homolog 3 (Drosophila)0.186
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.185
Fzd1frizzled homolog 1 (Drosophila)0.182
Rag1recombination activating gene 10.182
Clockcircadian locomotor output cycles kaput0.180
Meox2mesenchyme homeobox 20.179
Tbx2T-box 20.176
Acvrl1activin A receptor, type II-like 10.176
Engendoglin0.174
Notch2Notch gene homolog 2 (Drosophila)0.173
Nrp1neuropilin 10.172
Psen1presenilin 10.171
Wnt2bwingless related MMTV integration site 2b0.171
Csf1colony stimulating factor 1 (macrophage)0.167
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.167
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.162
Ptk2PTK2 protein tyrosine kinase 20.161
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.159
Vangl2vang-like 2 (van gogh, Drosophila)0.158
Sox9SRY-box containing gene 90.156
Ptgs2prostaglandin-endoperoxide synthase 20.154
RgnefRho-guanine nucleotide exchange factor0.149
Foxf1aforkhead box F1a0.148
Sox4SRY-box containing gene 40.146
Gpc3glypican 30.146
Gdnfglial cell line derived neurotrophic factor0.144
Pou3f3POU domain, class 3, transcription factor 30.144
Srcin1SRC kinase signaling inhibitor 10.142
Hand1heart and neural crest derivatives expressed transcript 10.142
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Elf1E74-like factor 10.055
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.043
Kdrkinase insert domain receptor0.041
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.027
Dusp1dual specificity phosphatase 10.026
Gpr116G protein-coupled receptor 1160.024
Prkchprotein kinase C, eta0.023
Podxlpodocalyxin-like0.021
Ctsl1cathepsin L10.021
Gja1gap junction protein, alpha 10.021
Hoxa2homeo box A20.021
Plxnd1plexin D10.020
Tcf4transcription factor 40.019
Thbdthrombomodulin0.019
Itpr2inositol 1,4,5-triphosphate receptor, type 20.018
Adam2ADAM metallopeptidase domain 20.018
Sox17SRY (sex determining region Y)-box 170.018
Nmur1neuromedin U receptor 10.018
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.018
Flt1FMS-related tyrosine kinase 10.017
Gpx3glutathione peroxidase 30.017
Cacna1gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.017
Jak1Janus kinase 10.016
Cybbcytochrome b-245, beta polypeptide0.016
Gata2GATA binding protein 20.015
Nr4a3nuclear receptor subfamily 4, group A, member 30.015
Notch4Notch homolog 4 (Drosophila)0.015
Prxperiaxin0.015
Egfl7EGF-like-domain, multiple 70.015
Fuca1fucosidase, alpha-L- 1, tissue0.015
LOC304903similar to Pappalysin-2 precursor (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP-E)0.014
Ednraendothelin receptor type A0.014
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.014
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.014
Nfianuclear factor I/A0.014
Ptpreprotein tyrosine phosphatase, receptor type, E0.013
Snai1snail homolog 1 (Drosophila)0.013
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.013
Hbe1hemoglobin, epsilon 10.013
Nfibnuclear factor I/B0.013
Edn1endothelin 10.013
Fgfr2fibroblast growth factor receptor 20.013
Lims1LIM and senescent cell antigen-like domains 10.012
Ndfip1Nedd4 family interacting protein 10.012
Fosl1fos-like antigen 10.012
Add2adducin 2 (beta)0.012
Stc1stanniocalcin 10.012
Pgcpplasma glutamate carboxypeptidase0.012
Pcsk1proprotein convertase subtilisin/kexin type 10.011
Ednrbendothelin receptor type B0.011
Rab3il1RAB3A interacting protein (rabin3)-like 10.011
Engendoglin0.011
Cpxm2carboxypeptidase X (M14 family), member 20.011
Timp2TIMP metallopeptidase inhibitor 20.011
LOC683626similar to limb-bud and heart0.011
Ptger4prostaglandin E receptor 4 (subtype EP4)0.011
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.011
Vipvasoactive intestinal peptide0.011
Htr75-hydroxytryptamine (serotonin) receptor 70.011
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.011
Plauplasminogen activator, urokinase0.011
Sstr1somatostatin receptor 10.011
Gucy2fguanylate cyclase 2F0.011
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.010
Ctsbcathepsin B0.010
Klf2Kruppel-like factor 2 (lung)0.010
Ptgs2prostaglandin-endoperoxide synthase 20.010
Cd38CD38 molecule0.010
Madcam1mucosal vascular addressin cell adhesion molecule 10.010
Bdnfbrain-derived neurotrophic factor0.010
Utrnutrophin0.010
Rxraretinoid X receptor alpha0.010
Tln1talin 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism