The network for 'mesenchymal to epithelial transition involved in metanephros morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mesenchymal to epithelial transition involved in metanephros morphogenesis

A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.

NameDescriptionProbabilityFunc Analog Organism
BMPR1Abone morphogenetic protein receptor, type IA1.000
MEOX1mesenchyme homeobox 10.999
NKX2-1NK2 homeobox 10.999
FSTL1follistatin-like 10.992
SOX2SRY (sex determining region Y)-box 20.984
CTNND1catenin (cadherin-associated protein), delta 10.820
NGFRnerve growth factor receptor0.474
COL2A1collagen, type II, alpha 10.410
BBS1Bardet-Biedl syndrome 10.401
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.358
FGF4fibroblast growth factor 40.286
WNT7Awingless-type MMTV integration site family, member 7A0.227
BMP2bone morphogenetic protein 20.214
ZFYVE9zinc finger, FYVE domain containing 90.183
WT1Wilms tumor 10.152
HNF1BHNF1 homeobox B0.141
MYOD1myogenic differentiation 10.137
SIM2single-minded homolog 2 (Drosophila)0.121
FOSL1FOS-like antigen 10.118
HOXC5homeobox C50.116
CYP26A1cytochrome P450, family 26, subfamily A, polypeptide 10.114
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.113
BMPR1Bbone morphogenetic protein receptor, type IB0.112
FOXF1forkhead box F10.111
HOXA11homeobox A110.103
DAXXdeath-domain associated protein0.093
FOXA2forkhead box A20.079
HNF1AHNF1 homeobox A0.078
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.078
CXCL3chemokine (C-X-C motif) ligand 30.077
GATA4GATA binding protein 40.073
HMGA2high mobility group AT-hook 20.072
GLI3GLI family zinc finger 30.067
HAND1heart and neural crest derivatives expressed 10.065
ADAMTSL4ADAMTS-like 40.062
BMP4bone morphogenetic protein 40.061
CRHR1corticotropin releasing hormone receptor 10.061
TT, brachyury homolog (mouse)0.058
TP73tumor protein p730.058
PTH2parathyroid hormone 20.058
TNFRSF12Atumor necrosis factor receptor superfamily, member 12A0.055
PRAMEF12PRAME family member 120.054
COL13A1collagen, type XIII, alpha 10.053
HCN4hyperpolarization activated cyclic nucleotide-gated potassium channel 40.053
POU4F1POU class 4 homeobox 10.053
FOXE1forkhead box E1 (thyroid transcription factor 2)0.053
FGF18fibroblast growth factor 180.052
FOXD3forkhead box D30.052
HOXC11homeobox C110.051
HOXD11homeobox D110.050
SLC30A3solute carrier family 30 (zinc transporter), member 30.049
SIX1SIX homeobox 10.047
HOXD13homeobox D130.047
LIFRleukemia inhibitory factor receptor alpha0.046
PAX7paired box 70.046
HOXB13homeobox B130.045
SOX1SRY (sex determining region Y)-box 10.045
CLCF1cardiotrophin-like cytokine factor 10.043
HES2hairy and enhancer of split 2 (Drosophila)0.043
HOXD1homeobox D10.043
OVOL1ovo-like 1(Drosophila)0.042
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.041
LHX1LIM homeobox 10.041
PYYpeptide YY0.041
HOXC10homeobox C100.040
KLF14Kruppel-like factor 140.040
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.039
LBX1ladybird homeobox 10.038
EN2engrailed homeobox 20.037
FEVFEV (ETS oncogene family)0.036
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.036
GSX2GS homeobox 20.035
GPR6G protein-coupled receptor 60.035
FOXA1forkhead box A10.034
RASSF1Ras association (RalGDS/AF-6) domain family member 10.034
NKX3-2NK3 homeobox 20.034
LMX1BLIM homeobox transcription factor 1, beta0.033
BMP7bone morphogenetic protein 70.033
SIX2SIX homeobox 20.033
HOXD9homeobox D90.032
PAX3paired box 30.032
HOXB8homeobox B80.032
PAX1paired box 10.031
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.030
KAZALD1Kazal-type serine peptidase inhibitor domain 10.030
VAX2ventral anterior homeobox 20.030
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.030
FZD8frizzled homolog 8 (Drosophila)0.029
NR4A3nuclear receptor subfamily 4, group A, member 30.029
PLK3polo-like kinase 30.027
RUNX1runt-related transcription factor 10.027
CALCAcalcitonin-related polypeptide alpha0.027
WNT1wingless-type MMTV integration site family, member 10.027
ALX4ALX homeobox 40.026
FOXO1forkhead box O10.026
FOXF2forkhead box F20.026
RAB3IL1RAB3A interacting protein (rabin3)-like 10.025
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgf8fibroblast growth factor 80.999
Fgfr2fibroblast growth factor receptor 20.999
Gli3GLI-Kruppel family member GLI30.999
Rargretinoic acid receptor, gamma0.998
Pax2paired box gene 20.996
Foxc1forkhead box C10.994
Fgfr1fibroblast growth factor receptor 10.993
Msx1homeobox, msh-like 10.991
Pax3paired box gene 30.977
Eya1eyes absent 1 homolog (Drosophila)0.974
Otx2orthodenticle homolog 2 (Drosophila)0.972
Lhx1LIM homeobox protein 10.970
Bmp7bone morphogenetic protein 70.966
Tbx1T-box 10.960
Gli2GLI-Kruppel family member GLI20.959
Sall4sal-like 4 (Drosophila)0.950
Pax8paired box gene 80.947
Sox9SRY-box containing gene 90.927
Hand1heart and neural crest derivatives expressed transcript 10.908
Foxc2forkhead box C20.903
Wnt3awingless-related MMTV integration site 3A0.901
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.899
Pitx2paired-like homeodomain transcription factor 20.870
Rarbretinoic acid receptor, beta0.835
Smosmoothened homolog (Drosophila)0.825
Gdnfglial cell line derived neurotrophic factor0.821
Bmp4bone morphogenetic protein 40.820
Prrx1paired related homeobox 10.818
Wnt4wingless-related MMTV integration site 40.805
Prrx2paired related homeobox 20.779
Dlx5distal-less homeobox 50.775
Msx2homeobox, msh-like 20.773
Hoxd11homeobox D110.754
Ror2receptor tyrosine kinase-like orphan receptor 20.726
Emx2empty spiracles homolog 2 (Drosophila)0.705
Tcfap2atranscription factor AP-2, alpha0.704
Fgf10fibroblast growth factor 100.678
Sox2SRY-box containing gene 20.667
Hoxa2homeobox A20.615
Alx4aristaless-like homeobox 40.610
Fgf3fibroblast growth factor 30.562
Rararetinoic acid receptor, alpha0.557
Hoxa1homeobox A10.528
Pou5f1POU domain, class 5, transcription factor 10.514
Retret proto-oncogene0.496
Ctnnb1catenin (cadherin associated protein), beta 10.496
Dkk1dickkopf homolog 1 (Xenopus laevis)0.483
Hoxa3homeobox A30.474
Otx1orthodenticle homolog 1 (Drosophila)0.449
Hand2heart and neural crest derivatives expressed transcript 20.373
Pax9paired box gene 90.363
NanogNanog homeobox0.359
Gscgoosecoid homeobox0.355
Isl1ISL1 transcription factor, LIM/homeodomain0.349
Twist2twist homolog 2 (Drosophila)0.335
Hoxa11homeobox A110.331
Tgfb2transforming growth factor, beta 20.320
Gbx2gastrulation brain homeobox 20.266
Hoxd3homeobox D30.249
Ptk7PTK7 protein tyrosine kinase 70.230
Col2a1collagen, type II, alpha 10.213
Pbx1pre B-cell leukemia transcription factor 10.207
Wnt10bwingless related MMTV integration site 10b0.197
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.196
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.189
Lef1lymphoid enhancer binding factor 10.181
Hmx3H6 homeobox 30.174
Sall3sal-like 3 (Drosophila)0.173
Lmx1bLIM homeobox transcription factor 1 beta0.168
Ednraendothelin receptor type A0.166
En1engrailed 10.162
Hmx1H6 homeobox 10.148
Hoxd13homeobox D130.146
Fgfr3fibroblast growth factor receptor 30.143
Hoxa13homeobox A130.142
Hoxb3homeobox B30.142
Tbx15T-box 150.141
Wnt1wingless-related MMTV integration site 10.133
Sall1sal-like 1 (Drosophila)0.127
Ntf3neurotrophin 30.122
Pou3f3POU domain, class 3, transcription factor 30.122
Nr0b1nuclear receptor subfamily 0, group B, member 10.121
Tcfap2ctranscription factor AP-2, gamma0.119
Bnc1basonuclin 10.118
Tbx2T-box 20.118
Hoxd9homeobox D90.113
Foxg1forkhead box G10.110
Alx3aristaless-like homeobox 30.109
Lama5laminin, alpha 50.108
Vax1ventral anterior homeobox containing gene 10.101
Lmx1aLIM homeobox transcription factor 1 alpha0.098
Efna4ephrin A40.097
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.092
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.092
Neurog1neurogenin 10.089
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism