The network for 'vesicle docking' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

vesicle docking

The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.

NameDescriptionProbabilityFunc Analog Organism
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.356
MON1BMON1 homolog B (yeast)0.298
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.284
SNAP25synaptosomal-associated protein, 25kDa0.232
CAV2caveolin 20.101
CAV1caveolin 1, caveolae protein, 22kDa0.071
PTPRFprotein tyrosine phosphatase, receptor type, F0.035
STX5syntaxin 50.026
PTENphosphatase and tensin homolog0.015
F2Rcoagulation factor II (thrombin) receptor0.013
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.013
SNAP23synaptosomal-associated protein, 23kDa0.012
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.012
FUNDC2FUN14 domain containing 20.012
PRKCDBPprotein kinase C, delta binding protein0.011
RABIFRAB interacting factor0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Snap25synaptosomal-associated protein 250.829
Vamp2vesicle-associated membrane protein 20.570
Sypsynaptophysin0.148
Prnpprion protein0.130
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.099
Htthuntingtin0.098
Dlg4discs, large homolog 4 (Drosophila)0.069
Syt2synaptotagmin II0.051
Stxbp5syntaxin binding protein 5 (tomosyn)0.048
L1camL1 cell adhesion molecule0.047
Dnm1dynamin 10.045
Rusc1RUN and SH3 domain containing 10.044
Mmp16matrix metallopeptidase 160.041
Clstn1calsyntenin 10.037
Uchl1ubiquitin carboxy-terminal hydrolase L10.033
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.031
Sos2son of sevenless homolog 2 (Drosophila)0.026
Ptpn9protein tyrosine phosphatase, non-receptor type 90.023
Lrrk2leucine-rich repeat kinase 20.022
Appamyloid beta (A4) precursor protein0.022
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.020
Dlg2discs, large homolog 2 (Drosophila)0.020
C78339expressed sequence C783390.020
Rab5aRAB5A, member RAS oncogene family0.019
Rnf103ring finger protein 1030.019
Nrsn1neurensin 10.018
Cntn1contactin 10.018
Inainternexin neuronal intermediate filament protein, alpha0.017
Cfl1cofilin 1, non-muscle0.016
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.015
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.014
Spna2spectrin alpha 20.014
Gosr1golgi SNAP receptor complex member 10.013
Dram2VDNA-damage regulated autophagy modulator 20.013
Tbk1TANK-binding kinase 10.013
Fgf12fibroblast growth factor 120.013
Homer1homer homolog 1 (Drosophila)0.013
Crmp1collapsin response mediator protein 10.012
Mtmr6myotubularin related protein 60.012
Nrcamneuron-glia-CAM-related cell adhesion molecule0.012
Epha5Eph receptor A50.012
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.012
Actr3ARP3 actin-related protein 3 homolog (yeast)0.012
Abi1abl-interactor 10.011
Pip5k1cphosphatidylinositol-4-phosphate 5-kinase, type 1 gamma0.011
Vamp4vesicle-associated membrane protein 40.011
Sncasynuclein, alpha0.011
Dlgap1discs, large (Drosophila) homolog-associated protein 10.011
Nap1l2nucleosome assembly protein 1-like 20.011
CadpsCa2+-dependent secretion activator0.011
Stx7syntaxin 70.011
Ly6hlymphocyte antigen 6 complex, locus H0.010
Rab3bRAB3B, member RAS oncogene family0.010
Sh3gl2SH3-domain GRB2-like 20.010
Mapk10mitogen-activated protein kinase 100.010
Grik2glutamate receptor, ionotropic, kainate 2 (beta 2)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Stxbp1syntaxin binding protein 10.527
Snap25synaptosomal-associated protein 250.441
Syn1synapsin I0.095
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.091
Apba2amyloid beta (A4) precursor protein-binding, family A, member 20.090
Stx1asyntaxin 1A (brain)0.073
Cplx1complexin 10.072
Syt1synaptotagmin I0.069
Syt11synaptotagmin XI0.068
Cplx2complexin 20.059
Camk2n2calcium/calmodulin-dependent protein kinase II inhibitor 20.047
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.046
Sncbsynuclein, beta0.045
Cntnap1contactin associated protein 10.044
Vamp2vesicle-associated membrane protein 20.041
Dlg4discs, large homolog 4 (Drosophila)0.027
Faim2Fas apoptotic inhibitory molecule 20.023
Ctxn1cortexin 10.022
Mapk9mitogen-activated protein kinase 90.020
Lrrc59leucine rich repeat containing 590.018
Kcnip3Kv channel interacting protein 3, calsenilin0.018
Necap2NECAP endocytosis associated 20.018
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.018
Stxbp2syntaxin binding protein 20.017
MaddMAP-kinase activating death domain0.016
Gnaqguanine nucleotide binding protein (G protein), q polypeptide0.016
Gnazguanine nucleotide binding protein (G protein), alpha z polypeptide0.016
CartptCART prepropeptide0.016
Prkcbprotein kinase C, beta0.016
Rab3aRAB3A, member RAS oncogene family0.014
Inainternexin neuronal intermediate filament protein, alpha0.014
Rph3arabphilin 3A0.013
Vamp1vesicle-associated membrane protein 10.013
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.012
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.012
Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit0.012
Mapk10mitogen activated protein kinase 100.012
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.012
Hpcal4hippocalcin-like 40.012
Mcf2lMCF.2 cell line derived transforming sequence-like0.011
Tnrtenascin R0.011
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.011
Unc5aunc-5 homolog A (C. elegans)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
VPS41Vps41p0.506
SEC10Sec10p0.382
PEP5Pep5p0.368
SEC6Sec6p0.350
SEC1Sec1p0.347
SEC9Sec9p0.345
VAM7Vam7p0.218
VPS45Vps45p0.202
SEC8Sec8p0.200
VAM6Vam6p0.127
VPS16Vps16p0.117
YKT6Ykt6p0.111
SRO7Sro7p0.110
YPT1Ypt1p0.096
SEC17Sec17p0.088
SEC4Sec4p0.087
VPS3Vps3p0.085
TLG2Tlg2p0.084
MSO1Mso1p0.077
PEP3Pep3p0.071
SEC2Sec2p0.060
SNC2Snc2p0.056
SFT1Sft1p0.052
SSO1Sso1p0.046
RSN1Rsn1p0.046
YIP3Yip3p0.043
YIP4Yip4p0.038
VPS21Vps21p0.037
ATG23Atg23p0.036
VPS51Vps51p0.036
VPS71Vps71p0.031
SFB2Sfb2p0.030
GDI1Gdi1p0.027
EXO84Exo84p0.026
SEC15Sec15p0.025
VPS38Vps38p0.024
SRD1Srd1p0.023
ARP10Arp10p0.022
ATG11Atg11p0.021
SLY1Sly1p0.021
YLR264C-Ahypothetical protein0.021
CUP1-1Cup1-1p0.020
YAR068Whypothetical protein0.020
LEU2Leu2p0.020
SAC7Sac7p0.020
EXO70Exo70p0.019
ABP140Abp140p0.019
ARG8Arg8p0.019
SEC5Sec5p0.019
YOL038C-Ahypothetical protein0.018
SWC7Swc7p0.018
YLR162Whypothetical protein0.018
MER1Mer1p0.018
YLR211Chypothetical protein0.017
HUG1Hug1p0.017
PAR32Par32p0.017
VPS36Vps36p0.016
URA3Ura3p0.016
MMT1Mmt1p0.016
YLR042Chypothetical protein0.016
HXT3Hxt3p0.016
ATP6Atp6p0.016
YAR066Whypothetical protein0.015
CPD1Cpd1p0.015
YBR013Chypothetical protein0.015
SEC3Sec3p0.015
RTT105Rtt105p0.015
OPT2Opt2p0.015
HOHop0.015
YPR157Whypothetical protein0.015
SRP54Srp54p0.015
SEN54Sen54p0.015
YIR035Chypothetical protein0.015
ZPS1Zps1p0.015
AAD15Aad15p0.015
HPF1Hpf1p0.015
TFA1Tfa1p0.014
YPT7Ypt7p0.014
AVL9Avl9p0.014
AUA1Aua1p0.014
KAP104Kap104p0.014
BET3Bet3p0.014
LCB3Lcb3p0.014
SPL2Spl2p0.014
YOL013W-Ahypothetical protein0.013
ALT2Alt2p0.013
CHA1Cha1p0.013
PRS2Prs2p0.013
FMT1Fmt1p0.013
KEL3Kel3p0.013
RHO1Rho1p0.013
YMR317Whypothetical protein0.013
BSC1Bsc1p0.013
IZH4Izh4p0.013
MF(ALPHA)2Mf(alpha)2p0.013
RNP1Rnp1p0.013
CRP1Crp1p0.013
YKR075Chypothetical protein0.013
SSO2Sso2p0.013
DUR1,2Dur1,2p0.013