The network for 'intermediate filament organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

intermediate filament organization

Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

NameDescriptionProbabilityFunc Analog Organism
KRT15keratin 151.000
KRT6Bkeratin 6B1.000
KRT19keratin 190.998
KRT18keratin 180.996
UBQLN1ubiquilin 10.995
KRT17keratin 170.985
KRT8keratin 80.982
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.950
KRT14keratin 140.924
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.816
MTMR12myotubularin related protein 120.716
KRT6Akeratin 6A0.697
KRT1keratin 10.690
PPP2R2Bprotein phosphatase 2, regulatory subunit B, beta0.594
KRT5keratin 50.547
PSEN1presenilin 10.510
JUPjunction plakoglobin0.312
SMAD9SMAD family member 90.270
KRT34keratin 340.266
KRT81keratin 810.259
MTM1myotubularin 10.252
TP63tumor protein p630.251
KRT16keratin 160.239
PKP2plakophilin 20.237
KRT33Bkeratin 33B0.233
TRIM29tripartite motif containing 290.221
EPS15epidermal growth factor receptor pathway substrate 150.220
TEKT4tektin 40.196
KRT2keratin 20.194
SPRR1Asmall proline-rich protein 1A0.187
KRT32keratin 320.185
ERBB2IPerbb2 interacting protein0.176
KRT36keratin 360.165
EXOC8exocyst complex component 80.164
MARK3MAP/microtubule affinity-regulating kinase 30.160
KRT31keratin 310.111
MTMR9myotubularin related protein 90.103
KRT13keratin 130.094
KRT4keratin 40.093
KRT75keratin 750.079
KRT9keratin 90.077
CCDC85Bcoiled-coil domain containing 85B0.075
CDH3cadherin 3, type 1, P-cadherin (placental)0.074
KRT33Akeratin 33A0.071
ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific )0.065
DSG3desmoglein 30.064
KRT35keratin 350.059
LAD1ladinin 10.047
KRT38keratin 380.040
SOS1son of sevenless homolog 1 (Drosophila)0.036
RHODras homolog gene family, member D0.034
FRMD5FERM domain containing 50.031
S100A14S100 calcium binding protein A140.031
DSC2desmocollin 20.031
KRT37keratin 370.030
COL17A1collagen, type XVII, alpha 10.029
KRT6Ckeratin 6C0.029
RHPN1rhophilin, Rho GTPase binding protein 10.026
PTPRJprotein tyrosine phosphatase, receptor type, J0.026
KLK10kallikrein-related peptidase 100.023
DSG2desmoglein 20.023
SPRR1Bsmall proline-rich protein 1B0.022
ITGB4integrin, beta 40.019
GJB5gap junction protein, beta 5, 31.1kDa0.019
BAG2BCL2-associated athanogene 20.018
GJB3gap junction protein, beta 3, 31kDa0.018
FAM107Afamily with sequence similarity 107, member A0.017
TRADDTNFRSF1A-associated via death domain0.017
SLURP1secreted LY6/PLAUR domain containing 10.017
KRT20keratin 200.017
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.016
DSG1desmoglein 10.016
C10orf10chromosome 10 open reading frame 100.016
PKP4plakophilin 40.016
RHCGRh family, C glycoprotein0.016
MTMR6myotubularin related protein 60.015
BAG3BCL2-associated athanogene 30.014
KRT7keratin 70.014
LY6Dlymphocyte antigen 6 complex, locus D0.013
SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome)0.013
KRT85keratin 850.013
SERPINB5serpin peptidase inhibitor, clade B (ovalbumin), member 50.013
PI3peptidase inhibitor 3, skin-derived0.013
HDAC11histone deacetylase 110.013
STON2stonin 20.012
SPRR3small proline-rich protein 30.012
BAIAP2BAI1-associated protein 20.012
LYPD3LY6/PLAUR domain containing 30.011
ALOX12arachidonate 12-lipoxygenase0.011
MT4metallothionein 40.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.998
Krt17keratin 170.983
Krt6akeratin 6A0.972
Krt19keratin 190.932
Krt5keratin 50.922
Foxn1forkhead box N10.823
Krtap8-1keratin associated protein 8-10.807
Pkp1plakophilin 10.789
Krt14keratin 140.781
Cldn4claudin 40.720
Sprr1asmall proline-rich protein 1A0.646
Krt27keratin 270.592
Krt33bkeratin 33B0.579
Krt8keratin 80.559
Nefmneurofilament, medium polypeptide0.522
Serpinb5serine (or cysteine) peptidase inhibitor, clade B, member 50.520
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.478
Lgals7lectin, galactose binding, soluble 70.460
Krt13keratin 130.411
Krt7keratin 70.401
Krt72-pskeratin 72, pseudogene0.393
Krt35keratin 350.379
Dlx3distal-less homeobox 30.353
Krt86keratin 860.343
Prss1protease, serine, 1 (trypsin 1)0.323
Krt71keratin 710.312
Krt1keratin 10.290
Psapl1prosaposin-like 10.287
Krt33akeratin 33A0.284
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.228
Padi3peptidyl arginine deiminase, type III0.217
Epha2Eph receptor A20.215
S100a14S100 calcium binding protein A140.210
Pthlhparathyroid hormone-like peptide0.197
Tubb2ctubulin, beta 2C0.193
Krtap6-2keratin associated protein 6-20.186
Krt85keratin 850.184
Krt25keratin 250.181
Fgf6fibroblast growth factor 60.174
Il1f5interleukin 1 family, member 5 (delta)0.173
Trp63transformation related protein 630.171
Alox8arachidonate 8-lipoxygenase0.169
Syt8synaptotagmin VIII0.168
Krt6bkeratin 6B0.166
Klk6kallikrein related-peptidase 60.165
Gfapglial fibrillary acidic protein0.159
Cldn7claudin 70.154
Krt34keratin 340.148
Krt36keratin 360.137
Krt4keratin 40.133
S100a3S100 calcium binding protein A30.129
Krt75keratin 750.128
Krt32keratin 320.127
Inainternexin neuronal intermediate filament protein, alpha0.123
Cdcp1CUB domain containing protein 10.123
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.122
Neflneurofilament, light polypeptide0.116
Krtdapkeratinocyte differentiation associated protein0.114
Krt16keratin 160.113
Wnt10awingless related MMTV integration site 10a0.110
Mt4metallothionein 40.109
Krtap3-3keratin associated protein 3-30.108
Gm10229predicted gene 102290.105
Trim29tripartite motif-containing 290.103
Krtap3-1keratin associated protein 3-10.103
Pitx1paired-like homeodomain transcription factor 10.100
1600029D21RikRIKEN cDNA 1600029D21 gene0.099
Krt15keratin 150.097
Tcfap2ctranscription factor AP-2, gamma0.096
Capn8calpain 80.095
Cyp2b19cytochrome P450, family 2, subfamily b, polypeptide 190.091
Wfdc2WAP four-disulfide core domain 20.083
Krt77keratin 770.080
NapbN-ethylmaleimide sensitive fusion protein attachment protein beta0.078
Cryabcrystallin, alpha B0.069
Tmprss2transmembrane protease, serine 20.068
Dsg2desmoglein 20.068
Hoxb9homeobox B90.068
Crct1cysteine-rich C-terminal 10.067
Sprr3small proline-rich protein 30.066
Gm10228predicted gene 102280.065
Esrp1epithelial splicing regulatory protein 10.065
Krt82keratin 820.064
Krt78keratin 780.062
Fxyd3FXYD domain-containing ion transport regulator 30.062
Krt31keratin 310.061
Lypd3Ly6/Plaur domain containing 30.059
Cldn3claudin 30.058
Edn2endothelin 20.058
2310033E01RikRIKEN cDNA 2310033E01 gene0.057
Klk7kallikrein related-peptidase 7 (chymotryptic, stratum corneum)0.057
Krt18keratin 180.056
Krt73keratin 730.056
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nefmneurofilament, medium polypeptide0.835
Neflneurofilament, light polypeptide0.754
Loxlysyl oxidase0.053
Nefhneurofilament, heavy polypeptide0.043
Anxa5annexin A50.040
Timp1TIMP metallopeptidase inhibitor 10.038
S100a6S100 calcium binding protein A60.033
Mgpmatrix Gla protein0.026
Inainternexin neuronal intermediate filament protein, alpha0.018
Col1a1collagen, type I, alpha 10.017
Dab2disabled homolog 2 (Drosophila)0.014
C1qbcomplement component 1, q subcomponent, B chain0.014
RGD1309537similar to Myosin regulatory light chain 2-A, smooth muscle isoform (Myosin RLC-A)0.013
CadpsCa++-dependent secretion activator0.012
C1rcomplement component 1, r subcomponent0.012
Olfm1olfactomedin 10.011
Pmp22peripheral myelin protein 220.011
Klk6kallikrein related-peptidase 60.011
Cplx1complexin 10.010
Kcnmb4potassium large conductance calcium-activated channel, subfamily M, beta member 40.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism