The network for 'rrna modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

rrna modification

The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.

NameDescriptionProbabilityFunc Analog Organism
NOP56NOP56 ribonucleoprotein homolog (yeast)0.997
GNL3guanine nucleotide binding protein-like 3 (nucleolar)0.959
NOP58NOP58 ribonucleoprotein homolog (yeast)0.908
RRS1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.892
NOLC1nucleolar and coiled-body phosphoprotein 10.840
DDX21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.686
FBLfibrillarin0.661
GAR1GAR1 ribonucleoprotein homolog (yeast)0.619
DKC1dyskeratosis congenita 1, dyskerin0.579
NCLnucleolin0.326
ODC1ornithine decarboxylase 10.268
PHB2prohibitin 20.180
IMPDH2IMP (inosine 5'-monophosphate) dehydrogenase 20.163
RSL1D1ribosomal L1 domain containing 10.137
NAF1nuclear assembly factor 1 homolog (S. cerevisiae)0.127
POLR1Cpolymerase (RNA) I polypeptide C, 30kDa0.124
EBNA1BP2EBNA1 binding protein 20.122
MYBBP1AMYB binding protein (P160) 1a0.114
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.114
PA2G4proliferation-associated 2G4, 38kDa0.094
MKI67IPMKI67 (FHA domain) interacting nucleolar phosphoprotein0.092
PRMT1protein arginine methyltransferase 10.091
FTSJ3FtsJ homolog 3 (E. coli)0.083
NAT10N-acetyltransferase 10 (GCN5-related)0.079
MAK16MAK16 homolog (S. cerevisiae)0.074
LYARLy1 antibody reactive homolog (mouse)0.071
NOP14NOP14 nucleolar protein homolog (yeast)0.070
RUVBL1RuvB-like 1 (E. coli)0.065
APEX1APEX nuclease (multifunctional DNA repair enzyme) 10.058
PPANpeter pan homolog (Drosophila)0.055
NHP2L1NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)0.052
PUS7pseudouridylate synthase 7 homolog (S. cerevisiae)0.050
EMG1EMG1 nucleolar protein homolog (S. cerevisiae)0.043
EIF3Deukaryotic translation initiation factor 3, subunit D0.041
UTP18UTP18, small subunit (SSU) processome component, homolog (yeast)0.038
NXT1NTF2-like export factor 10.036
C10orf2chromosome 10 open reading frame 20.035
EIF3Geukaryotic translation initiation factor 3, subunit G0.035
DPCDdeleted in primary ciliary dyskinesia homolog (mouse)0.034
NUFIP1nuclear fragile X mental retardation protein interacting protein 10.029
CIRH1Acirrhosis, autosomal recessive 1A (cirhin)0.028
BZW2basic leucine zipper and W2 domains 20.028
ANP32Bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.028
MRTO4mRNA turnover 4 homolog (S. cerevisiae)0.027
KIAA0020KIAA00200.027
PPRC1peroxisome proliferator-activated receptor gamma, coactivator-related 10.025
NOP16NOP16 nucleolar protein homolog (yeast)0.024
KARSlysyl-tRNA synthetase0.022
LAS1LLAS1-like (S. cerevisiae)0.021
TSR1TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)0.021
PWP1PWP1 homolog (S. cerevisiae)0.021
DDX27DEAD (Asp-Glu-Ala-Asp) box polypeptide 270.021
C12orf45chromosome 12 open reading frame 450.020
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.019
LYRM4LYR motif containing 40.019
SF3A3splicing factor 3a, subunit 3, 60kDa0.018
CHCHD8coiled-coil-helix-coiled-coil-helix domain containing 80.018
RUVBL2RuvB-like 2 (E. coli)0.018
PUS1pseudouridylate synthase 10.018
RCL1RNA terminal phosphate cyclase-like 10.018
SSRP1structure specific recognition protein 10.017
WDR74WD repeat domain 740.016
SHQ1SHQ1 homolog (S. cerevisiae)0.016
SLC25A38solute carrier family 25, member 380.016
CBFBcore-binding factor, beta subunit0.016
EIF3Beukaryotic translation initiation factor 3, subunit B0.016
ALKBH2alkB, alkylation repair homolog 2 (E. coli)0.016
WDR3WD repeat domain 30.015
PABPC4poly(A) binding protein, cytoplasmic 4 (inducible form)0.015
PITPNBphosphatidylinositol transfer protein, beta0.015
HNRNPABheterogeneous nuclear ribonucleoprotein A/B0.014
RBM28RNA binding motif protein 280.014
TGS1trimethylguanosine synthase 10.014
WDR43WD repeat domain 430.014
RRP1Bribosomal RNA processing 1 homolog B (S. cerevisiae)0.014
DDX47DEAD (Asp-Glu-Ala-Asp) box polypeptide 470.013
ITPAinosine triphosphatase (nucleoside triphosphate pyrophosphatase)0.013
SSR1signal sequence receptor, alpha0.013
NIP7nuclear import 7 homolog (S. cerevisiae)0.013
RPIAribose 5-phosphate isomerase A0.012
UTP14AUTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)0.012
RPP40ribonuclease P/MRP 40kDa subunit0.012
PNO1partner of NOB1 homolog (S. cerevisiae)0.012
PTDSS1phosphatidylserine synthase 10.011
ABCE1ATP-binding cassette, sub-family E (OABP), member 10.011
DDX10DEAD (Asp-Glu-Ala-Asp) box polypeptide 100.011
PCID2PCI domain containing 20.010
C12orf24chromosome 12 open reading frame 240.010
UCK2uridine-cytidine kinase 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CBF5Cbf5p0.650
PXR1Pxr1p0.369
MTO1Mto1p0.337
PUS1Pus1p0.329
NAF1Naf1p0.287
YBL081Whypothetical protein0.286
TSR1Tsr1p0.284
MER1Mer1p0.255
GAR1Gar1p0.237
PRP28Prp28p0.190
YLR264C-Ahypothetical protein0.176
IMD4Imd4p0.175
YCR051Whypothetical protein0.172
MAK16Mak16p0.162
SUA5Sua5p0.161
BCP1Bcp1p0.157
NHP2Nhp2p0.147
ENP1Enp1p0.147
UTP18Utp18p0.146
SWM2Swm2p0.146
URA3Ura3p0.145
LTV1Ltv1p0.143
NOP6Nop6p0.143
SRD1Srd1p0.143
DIP2Dip2p0.136
FYV7Fyv7p0.133
LEU2Leu2p0.129
GFD2Gfd2p0.128
YOL038C-Ahypothetical protein0.123
ARG8Arg8p0.121
YGL006W-Ahypothetical protein0.115
YLR162Whypothetical protein0.112
YNL018Chypothetical protein0.112
HMS2Hms2p0.109
FCY21Fcy21p0.107
NRD1Nrd1p0.107
ATP6Atp6p0.106
ARP10Arp10p0.104
YBR013Chypothetical protein0.104
NOP10Nop10p0.101
RIO2Rio2p0.101
RKI1Rki1p0.099
RRP5Rrp5p0.099
PRS2Prs2p0.097
YOL013W-Ahypothetical protein0.097
RRP14Rrp14p0.096
YAL037C-Ahypothetical protein0.096
YPR157Whypothetical protein0.096
YNL067W-Bhypothetical protein0.096
HOHop0.095
SCM4Scm4p0.095
YDR034C-Ahypothetical protein0.094
ZPS1Zps1p0.093
YLR042Chypothetical protein0.092
LOT5Lot5p0.088
HPF1Hpf1p0.088
RRS1Rrs1p0.087
MTG2Mtg2p0.086
YGL235Whypothetical protein0.086
DUS1Dus1p0.086
AST1Ast1p0.086
YNL162W-Ahypothetical protein0.085
YLR040Chypothetical protein0.084
ALT2Alt2p0.082
CHA1Cha1p0.082
NOP8Nop8p0.082
RPS13Rps13p0.081
COS12Cos12p0.081
TSC3Tsc3p0.079
YPL067Chypothetical protein0.079
PTR2Ptr2p0.079
HEM3Hem3p0.079
YAR068Whypothetical protein0.079
YNL024Chypothetical protein0.078
PPM2Ppm2p0.078
YOL114Chypothetical protein0.077
YOR293C-Ahypothetical protein0.077
YML100W-Ahypothetical protein0.076
YIL151Chypothetical protein0.076
YLR412C-Ahypothetical protein0.076
YMR001C-Ahypothetical protein0.075
ADH2Adh2p0.075
UPS3Ups3p0.075
YCL001W-Bhypothetical protein0.075
HXT3Hxt3p0.074
YLR342W-Ahypothetical protein0.074
YKL068W-Ahypothetical protein0.073
YAL064Whypothetical protein0.073
YIR035Chypothetical protein0.073
QRI7Qri7p0.073
BSC1Bsc1p0.072
AUA1Aua1p0.072
PUS6Pus6p0.072
YLR406C-Ahypothetical protein0.071
HMRA1Hmra1p0.071
ICS3Ics3p0.071
DUS3Dus3p0.070
YPL216Whypothetical protein0.070
RIM2Rim2p0.070
YTM1Ytm1p0.070