Process View
The network for 'intermediate filament based process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
KRT15 | keratin 15 | 1.000 | |
KRT6B | keratin 6B | 1.000 | |
KRT19 | keratin 19 | 0.999 | |
ERBB2IP | erbb2 interacting protein | 0.997 | |
KRT6A | keratin 6A | 0.986 | |
KRT18 | keratin 18 | 0.985 | |
KRT8 | keratin 8 | 0.984 | |
KRT14 | keratin 14 | 0.973 | |
PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.958 | |
KRT17 | keratin 17 | 0.928 | |
KRT5 | keratin 5 | 0.903 | |
PSEN1 | presenilin 1 | 0.844 | |
SMAD9 | SMAD family member 9 | 0.839 | |
JUP | junction plakoglobin | 0.821 | |
MTMR12 | myotubularin related protein 12 | 0.804 | |
KRT34 | keratin 34 | 0.783 | |
APC | adenomatous polyposis coli | 0.756 | |
PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.711 | |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.696 | |
UBQLN1 | ubiquilin 1 | 0.680 | |
KRT33B | keratin 33B | 0.672 | |
EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.670 | |
KRT81 | keratin 81 | 0.627 | |
TP63 | tumor protein p63 | 0.623 | |
MTM1 | myotubularin 1 | 0.606 | |
CCDC85B | coiled-coil domain containing 85B | 0.500 | |
PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.494 | |
DTNA | dystrobrevin, alpha | 0.482 | |
TRIM29 | tripartite motif containing 29 | 0.428 | |
KRT16 | keratin 16 | 0.407 | |
SPRR1A | small proline-rich protein 1A | 0.405 | |
PKP2 | plakophilin 2 | 0.345 | |
KRT32 | keratin 32 | 0.337 | |
ITGB4 | integrin, beta 4 | 0.331 | |
EXOC8 | exocyst complex component 8 | 0.326 | |
ALB | albumin | 0.288 | |
DSP | desmoplakin | 0.281 | |
KRT1 | keratin 1 | 0.273 | |
TEKT4 | tektin 4 | 0.241 | |
DMD | dystrophin | 0.226 | |
KRT36 | keratin 36 | 0.193 | |
KIAA0408 | KIAA0408 | 0.193 | |
KRT4 | keratin 4 | 0.180 | |
MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.169 | |
KRT6C | keratin 6C | 0.166 | |
MTMR9 | myotubularin related protein 9 | 0.163 | |
TJP1 | tight junction protein 1 (zona occludens 1) | 0.157 | |
COL17A1 | collagen, type XVII, alpha 1 | 0.154 | |
DSG3 | desmoglein 3 | 0.143 | |
KRT75 | keratin 75 | 0.141 | |
KRT31 | keratin 31 | 0.141 | |
TOR1A | torsin family 1, member A (torsin A) | 0.138 | |
STON2 | stonin 2 | 0.133 | |
KRT33A | keratin 33A | 0.121 | |
KRT13 | keratin 13 | 0.100 | |
KRT2 | keratin 2 | 0.093 | |
KRT9 | keratin 9 | 0.089 | |
KRT37 | keratin 37 | 0.089 | |
IVL | involucrin | 0.083 | |
KRT38 | keratin 38 | 0.075 | |
PKP4 | plakophilin 4 | 0.075 | |
KRT35 | keratin 35 | 0.073 | |
GJB5 | gap junction protein, beta 5, 31.1kDa | 0.071 | |
KLK10 | kallikrein-related peptidase 10 | 0.071 | |
SPRR1B | small proline-rich protein 1B | 0.070 | |
EXOC1 | exocyst complex component 1 | 0.069 | |
RAD23B | RAD23 homolog B (S. cerevisiae) | 0.064 | |
BAIAP2 | BAI1-associated protein 2 | 0.061 | |
RHOD | ras homolog gene family, member D | 0.055 | |
SPRR3 | small proline-rich protein 3 | 0.052 | |
FRMD5 | FERM domain containing 5 | 0.052 | |
SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.052 | |
PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.048 | |
PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.047 | |
SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.044 | |
GJB3 | gap junction protein, beta 3, 31kDa | 0.042 | |
TJP2 | tight junction protein 2 (zona occludens 2) | 0.041 | |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.041 | |
KIAA1217 | KIAA1217 | 0.039 | |
SMAD4 | SMAD family member 4 | 0.038 | |
KIF5B | kinesin family member 5B | 0.038 | |
TOR1B | torsin family 1, member B (torsin B) | 0.038 | |
DSC3 | desmocollin 3 | 0.037 | |
DSC2 | desmocollin 2 | 0.036 | |
SOS1 | son of sevenless homolog 1 (Drosophila) | 0.036 | |
MTMR6 | myotubularin related protein 6 | 0.036 | |
PPL | periplakin | 0.035 | |
DSG1 | desmoglein 1 | 0.034 | |
LY6G6C | lymphocyte antigen 6 complex, locus G6C | 0.034 | |
KRT85 | keratin 85 | 0.034 | |
TCHP | trichoplein, keratin filament binding | 0.033 | |
ATF7IP | activating transcription factor 7 interacting protein | 0.033 | |
VIM | vimentin | 0.032 | |
S100A14 | S100 calcium binding protein A14 | 0.031 | |
BAG1 | BCL2-associated athanogene | 0.031 | |
PAX9 | paired box 9 | 0.030 | |
LOR | loricrin | 0.029 | |
RHPN1 | rhophilin, Rho GTPase binding protein 1 | 0.029 | |
LY6D | lymphocyte antigen 6 complex, locus D | 0.028 | |
CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.028 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
CELE_ZK1025.3 | Protein ZK1025.3 | 0.011 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
BEAF-32 | Boundary element-associated factor of 32kD | 0.335 | |
Set | CG4299 gene product from transcript CG4299-RA | 0.103 | |
Aos1 | CG12276 gene product from transcript CG12276-RA | 0.095 | |
phl | pole hole | 0.077 | |
CG9797 | CG9797 gene product from transcript CG9797-RA | 0.038 | |
Rpb11 | CG6840 gene product from transcript CG6840-RA | 0.038 | |
RPA2 | Replication protein A2 | 0.038 | |
U2af50 | U2 small nuclear riboprotein auxiliary factor 50 | 0.037 | |
CG6961 | CG6961 gene product from transcript CG6961-RA | 0.031 | |
baf | barrier to autointegration factor | 0.030 | |
Nup62 | Nucleoporin 62 | 0.025 | |
Nup50 | Nucleoporin 50 | 0.024 | |
U2af38 | U2 small nuclear riboprotein auxiliary factor 38 | 0.023 | |
CG8289 | CG8289 gene product from transcript CG8289-RA | 0.023 | |
Ssrp | Structure specific recognition protein | 0.021 | |
RnpS1 | RNA-binding protein S1 | 0.021 | |
Arp14D | Actin-related protein 14D | 0.021 | |
nop5 | CG10206 gene product from transcript CG10206-RA | 0.021 | |
mor | moira | 0.020 | |
MED22 | Mediator complex subunit 22 | 0.019 | |
CG12155 | CG12155 gene product from transcript CG12155-RA | 0.019 | |
CG14464 | CG14464 gene product from transcript CG14464-RC | 0.018 | |
l(2)03709 | lethal (2) 03709 | 0.017 | |
Su(var)205 | Suppressor of variegation 205 | 0.016 | |
CG2982 | CG2982 gene product from transcript CG2982-RB | 0.016 | |
CG3887 | CG3887 gene product from transcript CG3887-RA | 0.016 | |
Tif-IA | CG3278 gene product from transcript CG3278-RA | 0.016 | |
T-cp1 | Tcp1-like | 0.015 | |
CG11076 | CG11076 gene product from transcript CG11076-RB | 0.015 | |
E2f2 | E2F transcription factor 2 | 0.015 | |
AP-1sigma | CG5864 gene product from transcript CG5864-RA | 0.015 | |
Ripalpha | RPA-interacting protein alpha | 0.014 | |
Top2 | Topoisomerase 2 | 0.014 | |
CG17202 | CG17202 gene product from transcript CG17202-RA | 0.014 | |
CG6610 | CG6610 gene product from transcript CG6610-RA | 0.014 | |
G-ialpha65A | G protein alphai subunit 65A | 0.014 | |
CG2691 | CG2691 gene product from transcript CG2691-RA | 0.013 | |
CG7006 | CG7006 gene product from transcript CG7006-RA | 0.013 | |
CG5525 | CG5525 gene product from transcript CG5525-RA | 0.013 | |
Rpb5 | CG11979 gene product from transcript CG11979-RA | 0.013 | |
Arc-p34 | CG10954 gene product from transcript CG10954-RA | 0.013 | |
eIF4AIII | CG7483 gene product from transcript CG7483-RA | 0.013 | |
vig2 | CG11844 gene product from transcript CG11844-RB | 0.012 | |
Art1 | Arginine methyltransferase 1 | 0.012 | |
Prp8 | pre-mRNA processing factor 8 | 0.012 | |
CG10286 | CG10286 gene product from transcript CG10286-RA | 0.012 | |
CG14220 | CG14220 gene product from transcript CG14220-RA | 0.012 | |
Nedd8 | CG10679 gene product from transcript CG10679-RA | 0.011 | |
Su(var)3-9 | Suppressor of variegation 3-9 | 0.011 | |
CG1542 | CG1542 gene product from transcript CG1542-RA | 0.011 | |
CG11583 | CG11583 gene product from transcript CG11583-RA | 0.011 | |
Pdsw | CG8844 gene product from transcript CG8844-RA | 0.011 | |
mod | modulo | 0.011 | |
Ranbp9 | CG5252 gene product from transcript CG5252-RA | 0.011 | |
ATPsyn-gamma | ATP synthase-gamma chain | 0.011 | |
CG3436 | CG3436 gene product from transcript CG3436-RA | 0.011 | |
CG5220 | CG5220 gene product from transcript CG5220-RA | 0.010 | |
eIF2B-gamma | CG8190 gene product from transcript CG8190-RA | 0.010 | |
Crk | CG1587 gene product from transcript CG1587-RC | 0.010 | |
La | La autoantigen-like | 0.010 | |
Rrp1 | Recombination repair protein 1 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Krt17 | keratin 17 | 0.962 | |
Krt5 | keratin 5 | 0.952 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.947 | |
Krt6a | keratin 6A | 0.934 | |
Pafah1b1 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 | 0.914 | |
Krt19 | keratin 19 | 0.909 | |
Sprr1a | small proline-rich protein 1A | 0.894 | |
Krt14 | keratin 14 | 0.891 | |
Krtap8-1 | keratin associated protein 8-1 | 0.840 | |
Krt13 | keratin 13 | 0.811 | |
Pkp1 | plakophilin 1 | 0.777 | |
Nphp4 | nephronophthisis 4 (juvenile) homolog (human) | 0.768 | |
Krt1 | keratin 1 | 0.748 | |
Krt71 | keratin 71 | 0.736 | |
Ppl | periplakin | 0.706 | |
Tgm3 | transglutaminase 3, E polypeptide | 0.685 | |
Psapl1 | prosaposin-like 1 | 0.657 | |
Krt33b | keratin 33B | 0.578 | |
Krt35 | keratin 35 | 0.578 | |
Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.574 | |
Lgals7 | lectin, galactose binding, soluble 7 | 0.517 | |
Il1f5 | interleukin 1 family, member 5 (delta) | 0.489 | |
Krt72-ps | keratin 72, pseudogene | 0.472 | |
Krt7 | keratin 7 | 0.467 | |
Serpinb5 | serine (or cysteine) peptidase inhibitor, clade B, member 5 | 0.447 | |
Cdsn | corneodesmosin | 0.423 | |
Wnt10a | wingless related MMTV integration site 10a | 0.422 | |
Capn8 | calpain 8 | 0.416 | |
Krt33a | keratin 33A | 0.404 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.343 | |
Krt36 | keratin 36 | 0.340 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.335 | |
Dlx3 | distal-less homeobox 3 | 0.328 | |
Krt8 | keratin 8 | 0.325 | |
Sync | syncoilin | 0.319 | |
Egfr | epidermal growth factor receptor | 0.314 | |
Krt6b | keratin 6B | 0.314 | |
Krt86 | keratin 86 | 0.298 | |
Krtap6-2 | keratin associated protein 6-2 | 0.297 | |
Krt85 | keratin 85 | 0.288 | |
Pthlh | parathyroid hormone-like peptide | 0.280 | |
5430421N21Rik | RIKEN cDNA 5430421N21 gene | 0.255 | |
Nphp1 | nephronophthisis 1 (juvenile) homolog (human) | 0.238 | |
Krt84 | keratin 84 | 0.238 | |
Trp63 | transformation related protein 63 | 0.237 | |
Sfn | stratifin | 0.230 | |
Syt8 | synaptotagmin VIII | 0.222 | |
Lypd3 | Ly6/Plaur domain containing 3 | 0.218 | |
Des | desmin | 0.214 | |
Krt27 | keratin 27 | 0.211 | |
Tff1 | trefoil factor 1 | 0.209 | |
Klk6 | kallikrein related-peptidase 6 | 0.208 | |
Nefm | neurofilament, medium polypeptide | 0.205 | |
S100a3 | S100 calcium binding protein A3 | 0.205 | |
S100a14 | S100 calcium binding protein A14 | 0.199 | |
Trim29 | tripartite motif-containing 29 | 0.197 | |
Krtdap | keratinocyte differentiation associated protein | 0.196 | |
Alox8 | arachidonate 8-lipoxygenase | 0.187 | |
Krtap5-1 | keratin associated protein 5-1 | 0.159 | |
Calm4 | calmodulin 4 | 0.155 | |
Krt4 | keratin 4 | 0.149 | |
Pitx1 | paired-like homeodomain transcription factor 1 | 0.146 | |
Foxn1 | forkhead box N1 | 0.145 | |
Krtap3-1 | keratin associated protein 3-1 | 0.139 | |
Ly6g6c | lymphocyte antigen 6 complex, locus G6C | 0.139 | |
Krt82 | keratin 82 | 0.130 | |
Sprr3 | small proline-rich protein 3 | 0.130 | |
Crct1 | cysteine-rich C-terminal 1 | 0.128 | |
Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.126 | |
Nefl | neurofilament, light polypeptide | 0.125 | |
Epha2 | Eph receptor A2 | 0.125 | |
Krt15 | keratin 15 | 0.125 | |
Gfap | glial fibrillary acidic protein | 0.123 | |
Tacstd2 | tumor-associated calcium signal transducer 2 | 0.122 | |
Endou | endonuclease, polyU-specific | 0.121 | |
Krt32 | keratin 32 | 0.113 | |
Psca | prostate stem cell antigen | 0.110 | |
Slc46a2 | solute carrier family 46, member 2 | 0.110 | |
Rcvrn | recoverin | 0.103 | |
Padi3 | peptidyl arginine deiminase, type III | 0.103 | |
Cyp2b19 | cytochrome P450, family 2, subfamily b, polypeptide 19 | 0.102 | |
Sncb | synuclein, beta | 0.100 | |
Arhgef2 | rho/rac guanine nucleotide exchange factor (GEF) 2 | 0.100 | |
Slurp1 | secreted Ly6/Plaur domain containing 1 | 0.100 | |
Hr | hairless | 0.100 | |
Klk7 | kallikrein related-peptidase 7 (chymotryptic, stratum corneum) | 0.099 | |
Krt16 | keratin 16 | 0.098 | |
Ppt1 | palmitoyl-protein thioesterase 1 | 0.098 | |
Krtap16-8 | keratin associated protein 16-8 | 0.098 | |
Krt78 | keratin 78 | 0.096 | |
Mt4 | metallothionein 4 | 0.093 | |
Tagln3 | transgelin 3 | 0.091 | |
Asprv1 | aspartic peptidase, retroviral-like 1 | 0.089 | |
Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.089 | |
Prss22 | protease, serine, 22 | 0.084 | |
Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.082 | |
Krtap3-3 | keratin associated protein 3-3 | 0.082 | |
Gpr87 | G protein-coupled receptor 87 | 0.079 | |
Fgf9 | fibroblast growth factor 9 | 0.079 | |
Atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.078 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Nefl | neurofilament, light polypeptide | 0.645 | |
Nefm | neurofilament, medium polypeptide | 0.525 | |
Anxa2 | annexin A2 | 0.092 | |
Nefh | neurofilament, heavy polypeptide | 0.088 | |
Anxa5 | annexin A5 | 0.045 | |
Actc1 | actin, alpha, cardiac muscle 1 | 0.032 | |
Ina | internexin neuronal intermediate filament protein, alpha | 0.029 | |
Mgp | matrix Gla protein | 0.028 | |
Col5a2 | collagen, type V, alpha 2 | 0.027 | |
Hspb1 | heat shock protein 1 | 0.025 | |
Cplx1 | complexin 1 | 0.024 | |
Cox6c | cytochrome c oxidase, subunit VIc | 0.024 | |
Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | 0.022 | |
Slc16a3 | solute carrier family 16, member 3 (monocarboxylic acid transporter 4) | 0.022 | |
Spock2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 | 0.022 | |
Fn1 | fibronectin 1 | 0.021 | |
RGD1563319 | similar to RIKEN cDNA 6330512M04 gene | 0.020 | |
Fgf9 | fibroblast growth factor 9 | 0.020 | |
Cadps | Ca++-dependent secretion activator | 0.020 | |
Capg | capping protein (actin filament), gelsolin-like | 0.018 | |
Sparc | secreted protein, acidic, cysteine-rich (osteonectin) | 0.017 | |
Kcna1 | potassium voltage-gated channel, shaker-related subfamily, member 1 | 0.016 | |
Ifitm3 | interferon induced transmembrane protein 3 | 0.016 | |
Lox | lysyl oxidase | 0.016 | |
Uchl1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.016 | |
Crabp1 | cellular retinoic acid binding protein 1 | 0.016 | |
Kif5c | kinesin family member 5C | 0.015 | |
RGD1309906 | similar to RIKEN cDNA 2310004I24 gene | 0.015 | |
Chgb | chromogranin B | 0.015 | |
Cryab | crystallin, alpha B | 0.015 | |
Vgf | VGF nerve growth factor inducible | 0.015 | |
Flnc | filamin C, gamma | 0.013 | |
Sox10 | SRY (sex determining region Y)-box 10 | 0.013 | |
Klk6 | kallikrein related-peptidase 6 | 0.013 | |
Csrp3 | cysteine and glycine-rich protein 3 | 0.012 | |
Tagln | transgelin | 0.012 | |
Kcnmb4 | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 0.012 | |
Gal | galanin prepropeptide | 0.011 | |
Elavl2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.011 | |
Calcb | calcitonin-related polypeptide, beta | 0.011 | |
Sigmar1 | sigma non-opioid intracellular receptor 1 | 0.011 | |
Snap91 | synaptosomal-associated protein 91 | 0.011 | |
Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.011 | |
S1pr2 | sphingosine-1-phosphate receptor 2 | 0.011 | |
Capn2 | calpain 2 | 0.011 | |
Psmd4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.011 | |
Ckm | creatine kinase, muscle | 0.011 | |
Ctgf | connective tissue growth factor | 0.011 | |
Prph | peripherin | 0.011 | |
Ascl2 | achaete-scute complex homolog 2 (Drosophila) | 0.011 | |
P2ry2 | purinergic receptor P2Y, G-protein coupled, 2 | 0.010 | |
Scn3b | sodium channel, voltage-gated, type III, beta | 0.010 | |
Camp | cathelicidin antimicrobial peptide | 0.010 | |
Dynlrb1 | dynein light chain roadblock-type 1 | 0.010 |