The network for 'establishment of protein localization to mitochondrion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

establishment of protein localization to mitochondrion

The directed movement of a protein to a specific location in the mitochondrion.

NameDescriptionProbabilityFunc Analog Organism
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.998
HSPA1Bheat shock 70kDa protein 1B0.998
TIMM13translocase of inner mitochondrial membrane 13 homolog (yeast)0.963
BCL2B-cell CLL/lymphoma 20.932
BCL2L11BCL2-like 11 (apoptosis facilitator)0.924
MARCH5membrane-associated ring finger (C3HC4) 50.913
DNAJA1DnaJ (Hsp40) homolog, subfamily A, member 10.882
BAXBCL2-associated X protein0.866
TIMM10translocase of inner mitochondrial membrane 10 homolog (yeast)0.839
PPIDpeptidylprolyl isomerase D0.782
BCL2L1BCL2-like 10.770
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.709
HSPA1Aheat shock 70kDa protein 1A0.576
TIMM8Btranslocase of inner mitochondrial membrane 8 homolog B (yeast)0.571
BECN1beclin 1, autophagy related0.515
HSPA8heat shock 70kDa protein 80.497
NUB1negative regulator of ubiquitin-like proteins 10.450
MAP2K4mitogen-activated protein kinase kinase 40.448
BADBCL2-associated agonist of cell death0.446
MAPK8mitogen-activated protein kinase 80.411
DNAJB1DnaJ (Hsp40) homolog, subfamily B, member 10.356
TOMM70Atranslocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)0.277
MRPL24mitochondrial ribosomal protein L240.258
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.240
TP53BP2tumor protein p53 binding protein, 20.223
PAM16presequence translocase-associated motor 16 homolog (S. cerevisiae)0.219
PINK1PTEN induced putative kinase 10.218
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.215
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.214
STIP1stress-induced-phosphoprotein 10.193
BAK1BCL2-antagonist/killer 10.176
DNM1Ldynamin 1-like0.161
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.156
RABGGTBRab geranylgeranyltransferase, beta subunit0.148
TIMM9translocase of inner mitochondrial membrane 9 homolog (yeast)0.144
MEOX2mesenchyme homeobox 20.140
HUWE1HECT, UBA and WWE domain containing 10.126
G3BP2GTPase activating protein (SH3 domain) binding protein 20.125
CHORDC1cysteine and histidine-rich domain (CHORD) containing 10.123
TCP1t-complex 10.114
MAP3K7mitogen-activated protein kinase kinase kinase 70.106
HSPH1heat shock 105kDa/110kDa protein 10.105
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.104
BAG3BCL2-associated athanogene 30.104
TOMM22translocase of outer mitochondrial membrane 22 homolog (yeast)0.098
RNF144Bring finger protein 144B0.097
IDH3Bisocitrate dehydrogenase 3 (NAD+) beta0.096
PPP5Cprotein phosphatase 5, catalytic subunit0.095
SKA3spindle and kinetochore associated complex subunit 30.093
BIKBCL2-interacting killer (apoptosis-inducing)0.093
TIMM17Atranslocase of inner mitochondrial membrane 17 homolog A (yeast)0.087
SMCR7LSmith-Magenis syndrome chromosome region, candidate 7-like0.086
ST13suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)0.085
MAP3K1mitogen-activated protein kinase kinase kinase 10.080
MAGEH1melanoma antigen family H, 10.077
KIAA0664KIAA06640.077
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.077
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.076
HSPA9heat shock 70kDa protein 9 (mortalin)0.075
COQ3coenzyme Q3 homolog, methyltransferase (S. cerevisiae)0.069
EIF5eukaryotic translation initiation factor 50.068
CDK7cyclin-dependent kinase 70.067
TOMM20translocase of outer mitochondrial membrane 20 homolog (yeast)0.065
MRPS12mitochondrial ribosomal protein S120.063
TMED2transmembrane emp24 domain trafficking protein 20.062
TIMM8Atranslocase of inner mitochondrial membrane 8 homolog A (yeast)0.059
IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha0.056
DNAJA2DnaJ (Hsp40) homolog, subfamily A, member 20.053
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.053
ETF1eukaryotic translation termination factor 10.052
TIMM44translocase of inner mitochondrial membrane 44 homolog (yeast)0.051
NDUFB2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa0.048
UBE2G1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.046
CIAPIN1cytokine induced apoptosis inhibitor 10.046
CDC37cell division cycle 37 homolog (S. cerevisiae)0.045
NMD3NMD3 homolog (S. cerevisiae)0.045
NR4A1nuclear receptor subfamily 4, group A, member 10.045
MRPL35mitochondrial ribosomal protein L350.044
NUDCnuclear distribution gene C homolog (A. nidulans)0.043
SS18synovial sarcoma translocation, chromosome 180.043
AMBRA1autophagy/beclin-1 regulator 10.043
XPO7exportin 70.042
BZW1basic leucine zipper and W2 domains 10.040
TMX2thioredoxin-related transmembrane protein 20.040
NAA10N(alpha)-acetyltransferase 10, NatA catalytic subunit0.040
SERTAD4SERTA domain containing 40.038
GHITMgrowth hormone inducible transmembrane protein0.036
CANXcalnexin0.035
BCAP31B-cell receptor-associated protein 310.035
SLC25A46solute carrier family 25, member 460.035
SUGT1SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)0.034
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.034
PEX19peroxisomal biogenesis factor 190.033
KIF5Bkinesin family member 5B0.033
YAF2YY1 associated factor 20.033
TIMM23translocase of inner mitochondrial membrane 23 homolog (yeast) and translocase of inner mitochondrial membrane 23 homolog (yeast)0.033
TBK1TANK-binding kinase 10.031
CCNG1cyclin G10.030
DCTN6dynactin 60.030
EPRSglutamyl-prolyl-tRNA synthetase0.030
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
fkb-6Protein FKB-60.547
C34C12.8Protein C34C12.80.213
C30C11.4Protein C30C11.40.119
cct-1Protein CCT-10.119
eif-3.KProtein EIF-3.K0.097
dnj-13Protein DNJ-130.092
cct-6Protein CCT-60.089
daf-21Protein DAF-210.080
cct-2Protein CCT-20.070
CELE_F45H11.5Protein F45H11.50.070
cct-4Protein CCT-40.069
mrps-14Protein MRPS-140.063
dnj-12Protein DNJ-120.057
mrpl-12Protein MRPL-120.052
cyn-7Protein CYN-70.051
tomm-7Protein TOMM-70.047
tag-294Protein TAG-2940.041
cct-5Protein CCT-50.036
ttll-12Protein TTLL-120.036
tin-9.1Protein TIN-9.10.035
CELE_K08F4.2Protein K08F4.20.034
hrp-1Protein HRP-10.033
ddp-1Protein DDP-10.033
CELE_C01G10.8Protein C01G10.80.029
scpl-4Protein SCPL-40.029
cyn-1Protein CYN-10.027
cra-1Protein CRA-10.026
Y39A3CL.3Protein Y39A3CL.30.026
adr-1Protein ADR-10.026
tars-1Protein TARS-10.026
hsp-4Protein HSP-40.025
F31D4.2Protein F31D4.20.025
let-711Protein LET-7110.022
mag-1Protein MAG-10.022
hsp-6Protein HSP-60.022
F56D1.2Protein F56D1.20.021
CELE_Y106G6H.5Protein Y106G6H.50.020
hap-1Protein HAP-10.020
snr-5Protein SNR-50.020
uba-1Protein UBA-10.019
qars-1Protein QARS-10.019
hsp-1Protein HSP-10.018
eftu-2Protein EFTU-20.018
CELE_Y105E8A.11Protein Y105E8A.110.018
clk-1Protein CLK-10.017
CELE_Y53F4B.14Protein Y53F4B.140.016
T18D3.1Protein T18D3.10.016
F13G3.10Protein F13G3.100.016
rmo-1Protein RMO-10.016
tba-1Protein TBA-10.016
F31D4.9Protein F31D4.90.016
tag-210Protein TAG-2100.016
rsp-3Protein RSP-30.015
hpo-18Protein HPO-180.015
prp-8Protein PRP-80.015
icd-1Protein ICD-10.015
T06D8.5Protein T06D8.50.015
nap-1Protein NAP-10.015
mrps-21Protein MRPS-210.014
CELE_C10C6.6Protein C10C6.60.014
F33H2.3Protein F33H2.30.014
C36E8.1Protein C36E8.10.013
Y22D7AL.10Protein Y22D7AL.100.013
tin-13Protein TIN-130.013
dnj-21Protein DNJ-210.013
ahcy-1Protein AHCY-10.012
C30H6.7Protein C30H6.70.012
T20B12.7Protein T20B12.70.012
daf-1Protein DAF-10.012
dnj-19Protein DNJ-190.011
cls-2Protein CLS-20.011
CELE_Y69A2AR.3Protein Y69A2AR.30.011
sti-1Protein STI-10.011
unc-24Protein UNC-240.011
cdc-48.2Protein CDC-48.20.011
T09B4.9Protein T09B4.90.011
H17B01.4Protein H17B01.40.011
ima-3Protein IMA-30.011
ccf-1Protein CCF-10.010
CELE_Y116A8C.30Protein Y116A8C.300.010
cal-4Protein CAL-40.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Hspd1heat shock protein 1 (chaperonin)0.964
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.912
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.746
Rpgrip1lRpgrip1-like0.678
Mcl1myeloid cell leukemia sequence 10.494
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.424
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.356
Hspa8heat shock protein 80.347
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.341
BaxBCL2-associated X protein0.329
Iqcb1IQ calmodulin-binding motif containing 10.323
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.301
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.252
Hsph1heat shock 105kDa/110kDa protein 10.194
Grpel1GrpE-like 1, mitochondrial0.100
Canxcalnexin0.096
Pdcd6ipprogrammed cell death 6 interacting protein0.083
Ahi1Abelson helper integration site 10.079
Lrpprcleucine-rich PPR-motif containing0.060
Hspa9heat shock protein 90.057
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.056
Ndufaf4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 40.053
Dnaja3DnaJ (Hsp40) homolog, subfamily A, member 30.052
Timm8a1translocase of inner mitochondrial membrane 8 homolog a1 (yeast)0.042
Bak1BCL2-antagonist/killer 10.041
Tomm70atranslocase of outer mitochondrial membrane 70 homolog A (yeast)0.037
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.037
Ptpmt1protein tyrosine phosphatase, mitochondrial 10.035
Arpc4actin related protein 2/3 complex, subunit 40.035
Mta1metastasis associated 10.034
Immtinner membrane protein, mitochondrial0.031
Mks1Meckel syndrome, type 10.027
Nmd3NMD3 homolog (S. cerevisiae)0.027
Timm10translocase of inner mitochondrial membrane 10 homolog (yeast)0.026
Trp53transformation related protein 530.026
Pus1pseudouridine synthase 10.023
Hsp90b1heat shock protein 90, beta (Grp94), member 10.021
NapbN-ethylmaleimide sensitive fusion protein attachment protein beta0.021
Mfn2mitofusin 20.020
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.019
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.019
1110002N22RikRIKEN cDNA 1110002N22 gene0.019
Eprsglutamyl-prolyl-tRNA synthetase0.018
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.017
Bcl2B-cell leukemia/lymphoma 20.017
Mrpl46mitochondrial ribosomal protein L460.016
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.016
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.016
Afg3l2AFG3(ATPase family gene 3)-like 2 (yeast)0.016
Men1multiple endocrine neoplasia 10.015
Rab4bRAB4B, member RAS oncogene family0.015
Hspb1heat shock protein 10.013
Tuba4atubulin, alpha 4A0.012
Dlddihydrolipoamide dehydrogenase0.012
Chchd4coiled-coil-helix-coiled-coil-helix domain containing 40.012
Tubb6tubulin, beta 60.011
Mrpl10mitochondrial ribosomal protein L100.011
Mrps18amitochondrial ribosomal protein S18A0.011
Bag2BCL2-associated athanogene 20.011
Dnm1ldynamin 1-like0.010
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.010
Ube2fubiquitin-conjugating enzyme E2F (putative)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hspd1heat shock protein 1 (chaperonin)0.031
Hsph1heat shock 105/110 protein 10.024
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.018
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.018
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TIM23Tim23p1.000
TOM22Tom22p1.000
TOM40Tom40p1.000
TIM44Tim44p1.000
MIA40Mia40p1.000
TOM70Tom70p1.000
TIM18Tim18p1.000
TIM17Tim17p1.000
TIM50Tim50p1.000
SSC1Ssc1p0.999
SAM35Sam35p0.999
TIM10Tim10p0.999
TOM20Tom20p0.999
TOM5Tom5p0.998
PAM18Pam18p0.997
TIM54Tim54p0.991
SAM50Sam50p0.988
TIM9Tim9p0.974
TIM22Tim22p0.974
TIM13Tim13p0.966
PAM16Pam16p0.965
TOM7Tom7p0.962
FCJ1Fcj1p0.926
MIM1Mim1p0.924
TIM8Tim8p0.921
MDM10Mdm10p0.846
MAS2Mas2p0.823
TIM21Tim21p0.790
ERV1Erv1p0.781
STI1Sti1p0.761
MGR2Mgr2p0.753
MGE1Mge1p0.577
TIM12Tim12p0.532
YLR099W-Ahypothetical protein0.456
ACP1Acp1p0.422
SIS1Sis1p0.404
SSE1Sse1p0.362
HSP60Hsp60p0.356
CAB4Cab4p0.347
ALT1Alt1p0.289
MDJ1Mdj1p0.273
DNM1Dnm1p0.252
HEM2Hem2p0.234
YHB1Yhb1p0.217
YTA12Yta12p0.212
MDM38Mdm38p0.209
IMP1Imp1p0.207
UGO1Ugo1p0.205
PET112Pet112p0.202
BFR1Bfr1p0.198
SAM37Sam37p0.194
TOM6Tom6p0.193
PAM17Pam17p0.193
ATP12Atp12p0.189
YME1Yme1p0.168
MGR3Mgr3p0.155
RDL2Rdl2p0.148
RIM13Rim13p0.139
ATG13Atg13p0.135
SGT2Sgt2p0.125
CUE4Cue4p0.124
COX2Cox2p0.122
IMP2Imp2p0.120
MAS1Mas1p0.117
COQ8Coq8p0.112
ALO1Alo1p0.112
YDJ1Ydj1p0.109
MDM32Mdm32p0.107
MOG1Mog1p0.102
KAR2Kar2p0.102
ATP11Atp11p0.099
YFH1Yfh1p0.098
YER064Chypothetical protein0.096
AIM43Aim43p0.094
TPD3Tpd3p0.091
SSA2Ssa2p0.090
GRX5Grx5p0.090
PPA2Ppa2p0.089
YLR253Whypothetical protein0.086
YAH1Yah1p0.082
YBL039W-Bhypothetical protein0.080
CPR3Cpr3p0.076
OXA1Oxa1p0.074
RNR3Rnr3p0.074
UPS1Ups1p0.073
RIM2Rim2p0.073
NTA1Nta1p0.072
SSA3Ssa3p0.069
SPS100Sps100p0.068
COX20Cox20p0.068
ALD6Ald6p0.066
MTM1Mtm1p0.065
ECM15Ecm15p0.065
VMA13Vma13p0.063
GAL7Gal7p0.063
YLH47Ylh47p0.063
YLR031Whypothetical protein0.062
CLU1Clu1p0.062
MDV1Mdv1p0.060
FMP25Fmp25p0.059