The network for 'behavioral defense response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

behavioral defense response

A behavioral response seeking to protect an organism from an a perceived external threat to that organism.

NameDescriptionProbabilityFunc Analog Organism
BCL2L1BCL2-like 11.000
BAXBCL2-associated X protein0.727
MPDZmultiple PDZ domain protein0.672
HDAC4histone deacetylase 40.600
CRHR1corticotropin releasing hormone receptor 10.558
AMBRA1autophagy/beclin-1 regulator 10.519
BAK1BCL2-antagonist/killer 10.517
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.419
BECN1beclin 1, autophagy related0.377
BCL2L11BCL2-like 11 (apoptosis facilitator)0.355
DLG4discs, large homolog 4 (Drosophila)0.335
BADBCL2-associated agonist of cell death0.313
RAI1retinoic acid induced 10.280
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.250
RPL18Aribosomal protein L18a0.246
ATP5G3ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)0.216
MYLK2myosin light chain kinase 20.203
TP53BP2tumor protein p53 binding protein, 20.201
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.174
BIDBH3 interacting domain death agonist0.170
FKBP8FK506 binding protein 8, 38kDa0.145
BIKBCL2-interacting killer (apoptosis-inducing)0.135
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.119
PHLPP2PH domain and leucine rich repeat protein phosphatase 20.105
KIFC2kinesin family member C20.081
GLO1glyoxalase I0.076
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.071
VDAC2voltage-dependent anion channel 20.070
HIPK2homeodomain interacting protein kinase 20.066
DDX24DEAD (Asp-Glu-Ala-Asp) box polypeptide 240.064
UBXN2AUBX domain protein 2A0.060
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.060
LPLlipoprotein lipase0.059
WDR20WD repeat domain 200.059
DUSP23dual specificity phosphatase 230.058
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta0.055
BBC3BCL2 binding component 30.054
NIPSNAP1nipsnap homolog 1 (C. elegans)0.047
PLEKHA1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 10.047
EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 40.047
DLGAP1discs, large (Drosophila) homolog-associated protein 10.044
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.044
FHL1four and a half LIM domains 10.042
ZNF784zinc finger protein 7840.042
MAPK8mitogen-activated protein kinase 80.041
HDAC9histone deacetylase 90.040
EP300E1A binding protein p3000.040
ASCC2activating signal cointegrator 1 complex subunit 20.038
NDUFB3NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa0.037
FSTL4follistatin-like 40.036
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.035
PRDX1peroxiredoxin 10.035
NR4A1nuclear receptor subfamily 4, group A, member 10.034
NAF1nuclear assembly factor 1 homolog (S. cerevisiae)0.034
RNF144Bring finger protein 144B0.033
CRMP1collapsin response mediator protein 10.031
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.031
BCL2L2BCL2-like 20.031
DAPK1death-associated protein kinase 10.031
UVRAGUV radiation resistance associated gene0.030
PPP3R1protein phosphatase 3, regulatory subunit B, alpha0.030
ACTL6Bactin-like 6B0.029
GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 10.027
DLGAP2discs, large (Drosophila) homolog-associated protein 20.026
RAD23BRAD23 homolog B (S. cerevisiae)0.026
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.025
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.025
GRIA1glutamate receptor, ionotropic, AMPA 10.024
OR2AG1olfactory receptor, family 2, subfamily AG, member 10.024
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.024
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.023
PLXNA3plexin A30.023
AFF2AF4/FMR2 family, member 20.023
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)0.022
CADM3cell adhesion molecule 30.022
VDAC1voltage-dependent anion channel 10.022
DBN1drebrin 10.022
METAP1methionyl aminopeptidase 10.022
CA10carbonic anhydrase X0.021
GRIA4glutamate receptor, ionotrophic, AMPA 40.021
SPNS1spinster homolog 1 (Drosophila)0.021
EEA1early endosome antigen 10.021
HRKharakiri, BCL2 interacting protein (contains only BH3 domain)0.020
SOD1superoxide dismutase 1, soluble0.020
GRIK1glutamate receptor, ionotropic, kainate 10.020
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.019
EMX1empty spiracles homeobox 10.019
HK1hexokinase 10.019
WDR48WD repeat domain 480.019
SSTR3somatostatin receptor 30.019
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 10.019
NLGN1neuroligin 10.019
GRIA2glutamate receptor, ionotropic, AMPA 20.018
MAPK1mitogen-activated protein kinase 10.018
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)0.018
RIBC2RIB43A domain with coiled-coils 20.018
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.018
CCKBRcholecystokinin B receptor0.017
DLG2discs, large homolog 2 (Drosophila)0.017
ACAT2acetyl-CoA acetyltransferase 20.017
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Emx1empty spiracles homolog 1 (Drosophila)0.900
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.881
Gabrb2gamma-aminobutyric acid (GABA) A receptor, subunit beta 20.748
Neurod1neurogenic differentiation 10.455
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.422
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.421
Gad2glutamic acid decarboxylase 20.392
Grid1glutamate receptor, ionotropic, delta 10.310
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.287
Ascl1achaete-scute complex homolog 1 (Drosophila)0.240
Kiss1KiSS-1 metastasis-suppressor0.236
Shhsonic hedgehog0.230
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.220
Dab1disabled homolog 1 (Drosophila)0.214
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.195
Shc3src homology 2 domain-containing transforming protein C30.191
Cckbrcholecystokinin B receptor0.164
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.164
Cacng2calcium channel, voltage-dependent, gamma subunit 20.158
Adra2cadrenergic receptor, alpha 2c0.153
Gabra1gamma-aminobutyric acid (GABA) A receptor, subunit alpha 10.148
Bcl2B-cell leukemia/lymphoma 20.147
BaxBCL2-associated X protein0.111
Hand1heart and neural crest derivatives expressed transcript 10.110
Oprl1opioid receptor-like 10.101
Adrb1adrenergic receptor, beta 10.098
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.094
Dlg4discs, large homolog 4 (Drosophila)0.091
Neurod4neurogenic differentiation 40.090
Pax6paired box gene 60.090
Cntn4contactin 40.086
Grm8glutamate receptor, metabotropic 80.085
Slc12a5solute carrier family 12, member 50.085
Neurog2neurogenin 20.081
Pnpla2patatin-like phospholipase domain containing 20.079
Sstr4somatostatin receptor 40.078
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.076
Gabrg2gamma-aminobutyric acid (GABA) A receptor, subunit gamma 20.072
Scn1asodium channel, voltage-gated, type I, alpha0.071
Zfpm2zinc finger protein, multitype 20.067
Prph2peripherin 20.064
Syn2synapsin II0.063
Gabrb1gamma-aminobutyric acid (GABA) A receptor, subunit beta 10.061
Cux2cut-like homeobox 20.060
Oprk1opioid receptor, kappa 10.060
Nxph1neurexophilin 10.059
Otx2orthodenticle homolog 2 (Drosophila)0.059
Celf4CUGBP, Elav-like family member 40.058
Amelxamelogenin X chromosome0.057
Cdh10cadherin 100.057
Npas1neuronal PAS domain protein 10.056
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.056
MecomMDS1 and EVI1 complex locus0.055
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.055
Hdac4histone deacetylase 40.053
Dlgap1discs, large (Drosophila) homolog-associated protein 10.052
Pdx1pancreatic and duodenal homeobox 10.051
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.051
Grm1glutamate receptor, metabotropic 10.050
Alx3aristaless-like homeobox 30.049
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.049
Calb1calbindin 10.048
Lhx6LIM homeobox protein 60.048
Mef2cmyocyte enhancer factor 2C0.047
Pmaip1phorbol-12-myristate-13-acetate-induced protein 10.047
Ptf1apancreas specific transcription factor, 1a0.047
Grik4glutamate receptor, ionotropic, kainate 40.046
Gabra5gamma-aminobutyric acid (GABA) A receptor, subunit alpha 50.046
Nxph2neurexophilin 20.045
Tac2tachykinin 20.045
Htr45 hydroxytryptamine (serotonin) receptor 40.044
Chrm1cholinergic receptor, muscarinic 1, CNS0.044
Hrkharakiri, BCL2 interacting protein (contains only BH3 domain)0.044
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.043
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.043
Pde6aphosphodiesterase 6A, cGMP-specific, rod, alpha0.043
Tacr1tachykinin receptor 10.042
Arxaristaless related homeobox0.042
Npy5rneuropeptide Y receptor Y50.042
Slc32a1solute carrier family 32 (GABA vesicular transporter), member 10.042
Cplx1complexin 10.040
Rims1regulating synaptic membrane exocytosis 10.040
Drd2dopamine receptor D20.039
Hes2hairy and enhancer of split 2 (Drosophila)0.039
Neurod2neurogenic differentiation 20.039
Tcfap2btranscription factor AP-2 beta0.039
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.039
Trpc5transient receptor potential cation channel, subfamily C, member 50.038
Tgfb2transforming growth factor, beta 20.038
Rit2Ras-like without CAAX 20.037
Wnt7awingless-related MMTV integration site 7A0.037
Odz1odd Oz/ten-m homolog 1 (Drosophila)0.037
Nrsn1neurensin 10.035
Grik1glutamate receptor, ionotropic, kainate 10.034
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.034
Stx1bsyntaxin 1B0.034
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Insrrinsulin receptor-related receptor0.039
Lim2lens intrinsic membrane protein 20.028
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.020
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.019
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.016
Prp15proline-rich protein 150.015
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.013
Pip5k1cphosphatidylinositol-4-phosphate 5-kinase, type I, gamma0.013
Arnt2aryl hydrocarbon receptor nuclear translocator 20.012
Pparaperoxisome proliferator activated receptor alpha0.011
Scn8asodium channel, voltage gated, type VIII, alpha subunit0.011
Rgs14regulator of G-protein signaling 140.011
Necab1N-terminal EF-hand calcium binding protein 10.010
Grm6glutamate receptor, metabotropic 60.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism