The network for 'multicellular organism reproduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

multicellular organism reproduction

The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.

NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.978
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.957
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.680
TP53tumor protein p530.656
EP300E1A binding protein p3000.629
EGFRepidermal growth factor receptor0.605
CREBBPCREB binding protein0.591
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.589
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.344
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.317
SMAD2SMAD family member 20.317
ESR1estrogen receptor 10.310
NCOA3nuclear receptor coactivator 30.305
RB1retinoblastoma 10.293
CDK2cyclin-dependent kinase 20.284
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.282
SRPK2SRSF protein kinase 20.269
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.251
BRCA1breast cancer 1, early onset0.246
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.244
CSNK2A1casein kinase 2, alpha 1 polypeptide0.244
RBX1ring-box 1, E3 ubiquitin protein ligase0.228
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.212
PABPC1poly(A) binding protein, cytoplasmic 10.206
SNRPFsmall nuclear ribonucleoprotein polypeptide F0.203
U2AF2U2 small nuclear RNA auxiliary factor 20.202
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.200
SNRPBsmall nuclear ribonucleoprotein polypeptides B and B10.195
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.193
TCP1t-complex 10.188
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.187
GSK3Bglycogen synthase kinase 3 beta0.178
CALM1calmodulin 1 (phosphorylase kinase, delta)0.175
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.170
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.163
CCT6Achaperonin containing TCP1, subunit 6A (zeta 1)0.163
HNRNPKheterogeneous nuclear ribonucleoprotein K0.159
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.154
RHOAras homolog gene family, member A0.152
FLNAfilamin A, alpha0.151
SFNstratifin0.149
APCadenomatous polyposis coli0.144
PTPN1protein tyrosine phosphatase, non-receptor type 10.144
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.143
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.142
SMAD3SMAD family member 30.140
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.139
INSRinsulin receptor0.137
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.133
SP1Sp1 transcription factor0.132
PLCG1phospholipase C, gamma 10.131
CSNK2Bcasein kinase 2, beta polypeptide0.130
SNRPGsmall nuclear ribonucleoprotein polypeptide G0.130
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.130
CCT7chaperonin containing TCP1, subunit 7 (eta)0.126
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.123
RBM39RNA binding motif protein 390.122
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.121
CAND1cullin-associated and neddylation-dissociated 10.121
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.120
ATXN1ataxin 10.118
SF3A2splicing factor 3a, subunit 2, 66kDa0.118
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.117
SNRPEsmall nuclear ribonucleoprotein polypeptide E0.116
CAV1caveolin 1, caveolae protein, 22kDa0.114
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.112
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.111
SNRPD3small nuclear ribonucleoprotein D3 polypeptide 18kDa0.111
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.109
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.106
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.105
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.104
PRDX1peroxiredoxin 10.104
CDC25Acell division cycle 25 homolog A (S. pombe)0.104
SNRPD1small nuclear ribonucleoprotein D1 polypeptide 16kDa0.103
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.103
BRCA2breast cancer 2, early onset0.102
CCT2chaperonin containing TCP1, subunit 2 (beta)0.102
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.102
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.100
CUL1cullin 10.100
SIRT1sirtuin 10.098
EIF3Heukaryotic translation initiation factor 3, subunit H0.097
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.096
PTPN11protein tyrosine phosphatase, non-receptor type 110.094
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.094
SSBSjogren syndrome antigen B (autoantigen La)0.093
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.093
ARandrogen receptor0.091
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.090
GRB10growth factor receptor-bound protein 100.089
AKT1v-akt murine thymoma viral oncogene homolog 10.086
UBCubiquitin C0.085
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.083
UBR5ubiquitin protein ligase E3 component n-recognin 50.083
CCT8chaperonin containing TCP1, subunit 8 (theta)0.081
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.081
CSNK1Ecasein kinase 1, epsilon0.081
ATF2activating transcription factor 20.077
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.077
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-54Protein UNC-540.985
pha-4Protein PHA-40.984
egl-13Protein EGL-130.978
vab-3Protein VAB-30.971
lag-1Protein LAG-10.957
egl-18Protein EGL-180.951
npp-1Protein NPP-10.938
prp-8Protein PRP-80.938
egl-30Protein EGL-300.932
vha-8Protein VHA-80.927
par-5Protein PAR-50.921
hlh-2Protein HLH-20.920
mat-3Protein MAT-30.920
his-5Protein HIS-50.920
his-62Protein HIS-620.920
ruvb-1Protein RUVB-10.911
stip-1Protein STIP-10.906
pqn-59Protein PQN-590.900
his-47Protein HIS-470.895
cgh-1Protein CGH-10.893
mom-2Protein MOM-20.891
rpa-2Protein RPA-20.889
lin-53Protein LIN-530.885
unc-73Protein UNC-730.882
glp-1Protein GLP-10.881
let-502Protein LET-5020.881
his-48Protein HIS-480.877
F33D11.10Protein F33D11.100.876
npp-7Protein NPP-70.876
scc-1Protein SCC-10.876
unc-53Protein UNC-530.875
unc-62Protein UNC-620.875
unc-60Protein UNC-600.874
egg-1Protein EGG-10.873
eef-1A.1Protein EEF-1A.10.869
aos-1Protein AOS-10.866
rpl-3Protein RPL-30.864
lmn-1Protein LMN-10.862
sma-6Protein SMA-60.861
taf-5Protein TAF-50.860
gon-14Protein GON-140.860
cbd-1Protein CBD-10.859
csn-5Protein CSN-50.858
hel-1Protein HEL-10.856
snr-4Protein SNR-40.853
his-61Protein HIS-610.853
egl-15Protein EGL-150.850
T28D9.1Protein T28D9.10.848
his-1Protein HIS-10.843
rnr-1Protein RNR-10.842
W05F2.3Protein W05F2.30.839
tba-1Protein TBA-10.838
ceh-20Protein CEH-200.834
his-46Protein HIS-460.834
cye-1Protein CYE-10.830
mcm-2Protein MCM-20.830
his-64Protein HIS-640.829
gex-3Protein GEX-30.828
pos-1Protein POS-10.828
prp-3Protein PRP-30.825
his-30Protein HIS-300.816
pmk-1Protein PMK-10.815
klp-16Protein KLP-160.813
lin-13Protein LIN-130.812
gls-1Protein GLS-10.808
sem-5Protein SEM-50.808
mep-1Protein MEP-10.806
attf-2Protein ATTF-20.804
spr-5Protein SPR-50.803
pdfr-1Protein PDFR-10.801
lin-12Protein LIN-120.798
tbb-2Protein TBB-20.796
his-45Protein HIS-450.793
lin-29Protein LIN-290.792
tbb-1Protein TBB-10.792
ppp-1Protein PPP-10.791
fkb-6Protein FKB-60.791
syd-9Protein SYD-90.790
inx-13Protein INX-130.789
egg-6Protein EGG-60.788
gld-3Protein GLD-30.788
CELE_C16C10.4Protein C16C10.40.787
nhr-67Protein NHR-670.784
suf-1Protein SUF-10.784
hum-5Protein HUM-50.784
his-42Protein HIS-420.783
unc-59Protein UNC-590.783
arf-1.2Protein ARF-1.20.782
mes-4Protein MES-40.779
myo-3Protein MYO-30.779
rnp-6Protein RNP-60.778
hcp-3Protein HCP-30.772
dnc-2Protein DNC-20.771
rmd-1Protein RMD-10.769
icd-1Protein ICD-10.766
goa-1Protein GOA-10.764
his-32Protein HIS-320.761
dsh-2Protein DSH-20.760
rpt-5Protein RPT-50.760
unc-57Protein UNC-570.759
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox9aSRY-box containing gene 9a0.985
ptch2patched 20.949
smosmoothened homolog (Drosophila)0.772
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.759
myhz2myosin, heavy polypeptide 2, fast muscle specific0.722
gli1GLI-Kruppel family member 10.711
piwil1piwi-like 1 (Drosophila)0.655
sox9bSRY-box containing gene 9b0.648
tfap2atranscription factor AP-2 alpha0.615
nanos3nanos homolog 30.593
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.574
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.570
ptch1patched 10.568
bmp4bone morphogenetic protein 40.539
gpr126G protein-coupled receptor 1260.536
otpaorthopedia homolog a0.534
pkd2polycystic kidney disease 20.520
piwil2piwi-like 2 (Drosophila)0.506
neurodneurogenic differentiation0.488
axin1axin 10.485
prickle1aprickle-like 1 (Drosophila) a0.453
e2f5E2F transcription factor 50.453
alcambactivated leukocyte cell adhesion molecule b0.439
plcg1phospholipase C, gamma 10.428
gng3guanine nucleotide binding protein (G protein), gamma 30.404
sox2SRY-box containing gene 20.380
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.378
lamc1laminin, gamma 10.359
wnt11rwingless-type MMTV integration site family, member 11, related0.359
bocbrother of CDO0.351
ccnb1cyclin B10.342
ihhaIndian hedgehog homolog a0.334
igf1rbinsulin-like growth factor 1b receptor0.333
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.331
fanclFanconi anemia, complementation group L0.318
gro1groucho 10.318
hhiphedgehog interacting protein0.317
kirrel3lkin of IRRE like 3 like0.307
eng2aengrailed 2a0.306
sall4sal-like 4 (Drosophila)0.302
trpv6transient receptor potential cation channel, subfamily V, member 60.298
orgoogenesis-related gene0.298
dharmadharma0.288
sema3aasemaphorin 3aa0.279
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.279
brca2breast cancer 2, early onset0.278
bmp15bone morphogenetic protein 150.275
hmgb1ahigh-mobility group box 1a0.272
plagl2pleiomorphic adenoma gene-like 20.264
wnt11wingless-type MMTV integration site family, member 110.255
sox19aSRY-box containing gene 19a0.252
wt1awilms tumor 1a0.236
srfserum response factor0.230
per3period homolog 3 (Drosophila)0.230
sox32SRY-box containing gene 320.225
six1bsine oculis homeobox homolog 1b0.218
nop58NOP58 ribonucleoprotein homolog (yeast)0.216
foxo3bforkhead box O3b0.211
bmp2bbone morphogenetic protein 2b0.211
sox5SRY-box containing gene 50.210
hspd1heat shock 60kD protein 1 (chaperonin)0.210
tardbpTAR DNA binding protein0.209
tpbgltrophoblast glycoprotein-like0.209
prnprs3prion protein, related sequence 30.207
hoxb1bhomeo box B1b0.200
crabp2acellular retinoic acid binding protein 2, a0.199
brd4bromodomain containing 40.199
egr1early growth response 10.196
sap18sin3-associated polypeptide0.195
efnb2aephrin B2a0.194
pabpc1apoly A binding protein, cytoplasmic 1 a0.193
prox1prospero-related homeobox gene 10.189
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.186
tdrd1tudor domain containing 10.186
ck2bcasein kinase 2 beta0.177
tbpl2TATA box binding protein like 20.176
dlcdeltaC0.176
eif3deukaryotic translation initiation factor 3, subunit D0.175
gdf6agrowth differentiation factor 6a0.175
rab1aRAB1A, member RAS oncogene family0.174
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.167
gpc4glypican 40.165
mmp9matrix metalloproteinase 90.165
smad1MAD homolog 1 (Drosophila)0.161
hmga1ahigh mobility group AT-hook 1a0.158
ift88intraflagellar transport 88 homolog0.151
hspa5heat shock protein 50.149
twist1atwist1a0.149
shhasonic hedgehog a0.148
ptgs2aprostaglandin-endoperoxide synthase 2a0.146
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.145
dmrt3adoublesex and mab-3 related transcription factor 3a0.144
tagln2transgelin 20.144
vegfaavascular endothelial growth factor Aa0.142
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.142
disp1dispatched homolog 1 (Drosophila)0.138
slc25a3bsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b0.137
fgfr1afibroblast growth factor receptor 1a0.136
nesnestin0.135
acvr1bactivin A receptor, type IB0.134
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pipprolactin induced protein0.495
Gjb3gap junction protein, beta 30.489
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.469
Icam1intercellular adhesion molecule 10.408
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.388
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.376
Cd36CD36 molecule (thrombospondin receptor)0.372
Id3inhibitor of DNA binding 30.347
Atp12aATPase, H+/K+ transporting, nongastric, alpha polypeptide0.346
Prlhrprolactin releasing hormone receptor0.334
Kcnh1potassium voltage-gated channel, subfamily H (eag-related), member 10.314
Neflneurofilament, light polypeptide0.310
Hspa1aheat shock 70kD protein 1A0.305
Slco2a1solute carrier organic anion transporter family, member 2a10.299
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.295
Actbactin, beta0.285
Ifitm3interferon induced transmembrane protein 30.284
Scamp2secretory carrier membrane protein 20.272
Olr1493olfactory receptor gene Olr14930.268
Chrngcholinergic receptor, nicotinic, gamma0.267
Ccr1chemokine (C-C motif) receptor 10.259
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.259
Ednrbendothelin receptor type B0.258
Nr4a3nuclear receptor subfamily 4, group A, member 30.257
Grm8glutamate receptor, metabotropic 80.253
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.252
Ptprcprotein tyrosine phosphatase, receptor type, C0.251
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.251
Chrna2cholinergic receptor, nicotinic, alpha 2 (neuronal)0.249
Ctsbcathepsin B0.249
Gipgastric inhibitory polypeptide0.246
Mapk3mitogen activated protein kinase 30.246
FosFBJ osteosarcoma oncogene0.243
Svs4seminal vesicle secretory protein 40.243
Plauplasminogen activator, urokinase0.242
Arf4ADP-ribosylation factor 40.241
Msnmoesin0.241
Trhr2thyrotropin releasing hormone receptor 20.239
Il12binterleukin 12B0.234
Snap25synaptosomal-associated protein 250.233
Cgaglycoprotein hormones, alpha polypeptide0.233
Cdk2cyclin dependent kinase 20.229
P4hbprolyl 4-hydroxylase, beta polypeptide0.229
Fgf14fibroblast growth factor 140.228
Ppibpeptidylprolyl isomerase B0.228
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.228
Avpr2arginine vasopressin receptor 20.226
Zranb2zinc finger, RAN-binding domain containing 20.225
Gja1gap junction protein, alpha 10.224
Agtr2angiotensin II receptor, type 20.223
Gucy2fguanylate cyclase 2F0.223
Scnn1bsodium channel, nonvoltage-gated 1, beta0.223
Efna5ephrin A50.222
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.220
Cckbrcholecystokinin B receptor0.220
Bmpr1abone morphogenetic protein receptor, type IA0.220
Aqp9aquaporin 90.219
LOC246267resection-induced TPI (rs11)0.218
Cd46CD46 molecule, complement regulatory protein0.218
Eef2eukaryotic translation elongation factor 20.215
Cd44Cd44 molecule0.214
Grm2glutamate receptor, metabotropic 20.214
Thbdthrombomodulin0.214
Trhrthyrotropin releasing hormone receptor0.213
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.213
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.207
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.207
Tmpothymopoietin0.206
Prkcdprotein kinase C, delta0.206
Sox13SRY (sex determining region Y)-box 130.205
Catsper2cation channel, sperm associated 20.200
Hcrtr1hypocretin (orexin) receptor 10.197
Prkaa1protein kinase, AMP-activated, alpha 1 catalytic subunit0.196
Adam7ADAM metallopeptidase domain 70.193
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.193
Cd80Cd80 molecule0.191
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.190
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.189
Pfn1profilin 10.189
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.189
Lifleukemia inhibitory factor0.188
Testintestin gene0.188
Anxa5annexin A50.187
Hpcahippocalcin0.186
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.185
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.185
Ccl2chemokine (C-C motif) ligand 20.182
Ctsjcathepsin J0.181
GperG protein-coupled estrogen receptor 10.181
Slc14a2solute carrier family 14 (urea transporter), member 20.180
Calcrcalcitonin receptor0.179
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.178
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.177
Msmbmicroseminoprotein, beta0.176
Ppyr1pancreatic polypeptide receptor 10.176
Loxlysyl oxidase0.176
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.176
Adarb2adenosine deaminase, RNA-specific, B20.175
Kcnj16potassium inwardly-rectifying channel, subfamily J, member 160.174
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.174
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism