The network for 'cellular response to glucocorticoid stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to glucocorticoid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.

NameDescriptionProbabilityFunc Analog Organism
SMN1survival of motor neuron 1, telomeric1.000
ANXA1annexin A10.884
NRP1neuropilin 10.843
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.789
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.725
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.700
S100A10S100 calcium binding protein A100.695
RNF144Bring finger protein 144B0.672
APAF1apoptotic peptidase activating factor 10.624
TK1thymidine kinase 1, soluble0.601
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.561
CASP3caspase 3, apoptosis-related cysteine peptidase0.448
PLAUplasminogen activator, urokinase0.438
NRIP1nuclear receptor interacting protein 10.409
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.362
XIAPX-linked inhibitor of apoptosis0.360
ANXA5annexin A50.346
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.309
HBP1HMG-box transcription factor 10.299
EMP1epithelial membrane protein 10.298
IFNGR1interferon gamma receptor 10.294
LGALS1lectin, galactoside-binding, soluble, 10.292
PLATplasminogen activator, tissue0.292
CRHR1corticotropin releasing hormone receptor 10.254
FSTL1follistatin-like 10.207
S100A11S100 calcium binding protein A110.199
NCOA1nuclear receptor coactivator 10.193
TGFB3transforming growth factor, beta 30.168
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.166
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 50.160
ANXA4annexin A40.158
EIF3Feukaryotic translation initiation factor 3, subunit F0.158
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.155
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.146
MBNL1muscleblind-like (Drosophila)0.139
RICTORRPTOR independent companion of MTOR, complex 20.138
ANXA2annexin A20.135
ADAMTSL4ADAMTS-like 40.128
TMF1TATA element modulatory factor 10.127
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.116
SOCS1suppressor of cytokine signaling 10.113
THBS1thrombospondin 10.112
PLAURplasminogen activator, urokinase receptor0.107
MPDZmultiple PDZ domain protein0.106
ARNTaryl hydrocarbon receptor nuclear translocator0.097
DUSP6dual specificity phosphatase 60.093
NR1D2nuclear receptor subfamily 1, group D, member 20.093
JAG1jagged 10.093
KLHL24kelch-like 24 (Drosophila)0.089
ARRDC3arrestin domain containing 30.089
C16orf53chromosome 16 open reading frame 530.087
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.086
ARIH2ariadne homolog 2 (Drosophila)0.085
ZFYVE9zinc finger, FYVE domain containing 90.084
ITGB5integrin, beta 50.084
NMT2N-myristoyltransferase 20.083
GRIP1glutamate receptor interacting protein 10.079
RNF31ring finger protein 310.078
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.073
TM4SF1transmembrane 4 L six family member 10.073
PHLDA1pleckstrin homology-like domain, family A, member 10.073
CASP7caspase 7, apoptosis-related cysteine peptidase0.072
ADAM9ADAM metallopeptidase domain 90.071
MEF2Amyocyte enhancer factor 2A0.070
FNDC3Bfibronectin type III domain containing 3B0.068
IQGAP1IQ motif containing GTPase activating protein 10.067
MRPL41mitochondrial ribosomal protein L410.066
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.066
KLF4Kruppel-like factor 4 (gut)0.065
NCOA7nuclear receptor coactivator 70.064
TSC22D1TSC22 domain family, member 10.063
H3F3CH3 histone, family 3C0.062
TGFBR1transforming growth factor, beta receptor 10.061
STAT1signal transducer and activator of transcription 1, 91kDa0.059
ESR2estrogen receptor 2 (ER beta)0.059
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif, 10.059
BAXBCL2-associated X protein0.059
ORM1orosomucoid 10.057
NOMO1NODAL modulator 10.057
CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.056
S100A6S100 calcium binding protein A60.054
ACTA1actin, alpha 1, skeletal muscle0.054
KCTD17potassium channel tetramerisation domain containing 170.054
IL8interleukin 80.053
DNAJC1DnaJ (Hsp40) homolog, subfamily C, member 10.053
AHRaryl hydrocarbon receptor0.052
ALG2asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)0.052
PDCD6programmed cell death 60.051
NMIN-myc (and STAT) interactor0.050
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.048
TNFRSF12Atumor necrosis factor receptor superfamily, member 12A0.048
ACTN2actinin, alpha 20.048
NFE2L2nuclear factor (erythroid-derived 2)-like 20.047
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Casp4caspase 4, apoptosis-related cysteine peptidase0.962
Lyz2lysozyme 20.922
Vegfavascular endothelial growth factor A0.893
Ptpn11protein tyrosine phosphatase, non-receptor type 110.877
Pitx2paired-like homeodomain transcription factor 20.821
Ptgs2prostaglandin-endoperoxide synthase 20.812
H2-Ab1histocompatibility 2, class II antigen A, beta 10.689
Trim55tripartite motif-containing 550.674
Tgfb1transforming growth factor, beta 10.600
Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)0.592
Ren1renin 1 structural0.564
Pax3paired box gene 30.509
Hif1ahypoxia inducible factor 1, alpha subunit0.486
Gata4GATA binding protein 40.484
Dmddystrophin, muscular dystrophy0.456
Tgfbr2transforming growth factor, beta receptor II0.395
Agtr1aangiotensin II receptor, type 1a0.393
Fgfr2fibroblast growth factor receptor 20.392
Bmpr1abone morphogenetic protein receptor, type 1A0.375
Foxc1forkhead box C10.353
Nr3c1nuclear receptor subfamily 3, group C, member 10.349
Adam17a disintegrin and metallopeptidase domain 170.335
Gbp5guanylate binding protein 50.321
Nos1nitric oxide synthase 1, neuronal0.285
Osmroncostatin M receptor0.273
Csf1colony stimulating factor 1 (macrophage)0.267
H2-Eb1histocompatibility 2, class II antigen E beta0.262
Tgfb2transforming growth factor, beta 20.223
Stat3signal transducer and activator of transcription 30.213
Rb1retinoblastoma 10.206
H2-Aahistocompatibility 2, class II antigen A, alpha0.187
Trim63tripartite motif-containing 630.187
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.147
Leprleptin receptor0.134
Itgb1integrin beta 1 (fibronectin receptor beta)0.134
Casp1caspase 10.132
PycardPYD and CARD domain containing0.118
Pax6paired box gene 60.110
Fbn1fibrillin 10.105
WwoxWW domain-containing oxidoreductase0.101
Rxraretinoid X receptor alpha0.096
Ctnnb1catenin (cadherin associated protein), beta 10.095
Meox2mesenchyme homeobox 20.090
Shhsonic hedgehog0.088
Myf6myogenic factor 60.084
Klf3Kruppel-like factor 3 (basic)0.083
Il18interleukin 180.079
Il6stinterleukin 6 signal transducer0.079
Smad3MAD homolog 3 (Drosophila)0.078
Hbegfheparin-binding EGF-like growth factor0.077
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.077
Tgfbr1transforming growth factor, beta receptor I0.074
Plauplasminogen activator, urokinase0.070
Thbs1thrombospondin 10.070
Prlrprolactin receptor0.069
Myf5myogenic factor 50.068
Ptprcprotein tyrosine phosphatase, receptor type, C0.067
Vhlvon Hippel-Lindau tumor suppressor0.067
Egfrepidermal growth factor receptor0.067
Il1r1interleukin 1 receptor, type I0.064
Hand2heart and neural crest derivatives expressed transcript 20.063
Jag1jagged 10.063
Slc12a1solute carrier family 12, member 10.062
Errfi1ERBB receptor feedback inhibitor 10.061
Esr1estrogen receptor 1 (alpha)0.061
Nos3nitric oxide synthase 3, endothelial cell0.061
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.057
Gja1gap junction protein, alpha 10.054
Il1binterleukin 1 beta0.054
Aim2absent in melanoma 20.050
Apcadenomatosis polyposis coli0.050
Lhx3LIM homeobox protein 30.049
Nr2e1nuclear receptor subfamily 2, group E, member 10.048
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.047
Vdrvitamin D receptor0.046
H2-DMahistocompatibility 2, class II, locus DMa0.046
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.043
Socs5suppressor of cytokine signaling 50.042
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.042
Rbl2retinoblastoma-like 20.039
RoraRAR-related orphan receptor alpha0.038
Sox4SRY-box containing gene 40.037
Loxlysyl oxidase0.036
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.035
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.035
Pax7paired box gene 70.035
Nf1neurofibromatosis 10.035
Mybphmyosin binding protein H0.034
Klhl24kelch-like 24 (Drosophila)0.034
Tnni2troponin I, skeletal, fast 20.033
Cd14CD14 antigen0.033
Foxp3forkhead box P30.033
Map3k7mitogen-activated protein kinase kinase kinase 70.032
Esr2estrogen receptor 2 (beta)0.031
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Agtr1aangiotensin II receptor, type 1a0.511
Ephx1epoxide hydrolase 1, microsomal0.490
Serpina4serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 40.356
Itgb1integrin, beta 10.339
Idi1isopentenyl-diphosphate delta isomerase 10.334
Tgfbr2transforming growth factor, beta receptor II0.318
Bcl2B-cell CLL/lymphoma 20.305
Agxt2alanine-glyoxylate aminotransferase 20.295
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.290
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.283
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.278
Acsm2acyl-CoA synthetase medium-chain family member 20.275
RT1-BbRT1 class II, locus Bb0.267
Apoa4apolipoprotein A-IV0.260
Col12a1collagen, type XII, alpha 10.251
Gstm1glutathione S-transferase mu 10.250
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.246
Tgfbr3transforming growth factor, beta receptor III0.245
Pla1aphospholipase A1 member A0.239
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.236
Lgals3lectin, galactoside-binding, soluble, 30.234
Fgbfibrinogen beta chain0.227
Slc8a3solute carrier family 8 (sodium/calcium exchanger), member 30.227
Gsta3glutathione S-transferase A30.223
Prlrprolactin receptor0.218
Slc22a7solute carrier family 22 (organic anion transporter), member 70.217
Fxyd4FXYD domain-containing ion transport regulator 40.216
Slc1a2solute carrier family 1 (glial high affinity glutamate transporter), member 20.207
Pcdhb12protocadherin beta 120.207
Testintestin gene0.205
Mmp2matrix metallopeptidase 20.202
Mgst1microsomal glutathione S-transferase 10.200
Dnase1l3deoxyribonuclease 1-like 30.197
Metmet proto-oncogene0.193
G6pcglucose-6-phosphatase, catalytic subunit0.193
COX1cytochrome c oxidase subunit 10.185
Fgf21fibroblast growth factor 210.185
Aqp8aquaporin 80.184
Slco1a1solute carrier organic anion transporter family, member 1a10.183
Flt1FMS-related tyrosine kinase 10.180
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.178
LOC494499LOC494499 protein0.176
Plauplasminogen activator, urokinase0.175
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.175
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.172
MrgprfMAS-related GPR, member F0.171
Glra1glycine receptor, alpha 10.170
Slco2a1solute carrier organic anion transporter family, member 2a10.168
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.164
Cyb5acytochrome b5 type A (microsomal)0.164
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.153
RT1-BaRT1 class II, locus Ba0.151
Procprotein C0.149
Fn1fibronectin 10.147
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.147
Cd4Cd4 molecule0.146
Ctsjcathepsin J0.146
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.145
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.141
Mgst2microsomal glutathione S-transferase 20.140
Klkb1kallikrein B, plasma 10.139
Atp7bATPase, Cu++ transporting, beta polypeptide0.138
Serpinb3aserine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A0.136
Gja6gap junction protein, alpha 60.134
Cd14CD14 molecule0.130
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.130
Cyp2g1cytochrome P450, family 2, subfamily g, polypeptide 10.129
C8bcomplement component 8, beta polypeptide0.129
P22k15cystatin related protein 20.128
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.125
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.124
Chrna7cholinergic receptor, nicotinic, alpha 70.124
Anxa1annexin A10.122
S100a10S100 calcium binding protein A100.121
Ggt5gamma-glutamyltransferase 50.118
Mcpt3mast cell peptidase 30.118
Jak2Janus kinase 20.115
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.114
Asgr2asialoglycoprotein receptor 20.113
Csf1colony stimulating factor 1 (macrophage)0.113
Gsta5glutathione S-transferase Yc2 subunit0.111
Il1rl1interleukin 1 receptor-like 10.108
Insrrinsulin receptor-related receptor0.106
Hes3hairy and enhancer of split 3 (Drosophila)0.105
Atp2a3ATPase, Ca++ transporting, ubiquitous0.105
Shank2SH3 and multiple ankyrin repeat domains 20.105
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.105
Onecut1one cut homeobox 10.104
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.103
Gja1gap junction protein, alpha 10.103
Lmnalamin A0.100
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.099
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.098
Crygfcrystallin, gamma F0.097
Smad7SMAD family member 70.097
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.094
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism