The network for 'interspecies interaction between organisms' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

interspecies interaction between organisms

Any process in which an organism has an effect on an organism of a different species.

NameDescriptionProbabilityFunc Analog Organism
THOC4THO complex 40.999
RNF11ring finger protein 110.997
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.994
THOC5THO complex 50.992
SP1Sp1 transcription factor0.992
TP53tumor protein p530.991
SMURF2SMAD specific E3 ubiquitin protein ligase 20.990
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.989
IFIT3interferon-induced protein with tetratricopeptide repeats 30.989
WWP2WW domain containing E3 ubiquitin protein ligase 20.986
SP110SP110 nuclear body protein0.985
IFI44interferon-induced protein 440.985
OAS12',5'-oligoadenylate synthetase 1, 40/46kDa0.983
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.980
IFI44Linterferon-induced protein 44-like0.979
JUNjun proto-oncogene0.964
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.962
SMAD3SMAD family member 30.956
PLSCR1phospholipid scramblase 10.952
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.950
IFITM1interferon induced transmembrane protein 1 (9-27)0.939
MYD88myeloid differentiation primary response gene (88)0.933
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.931
UBE2L6ubiquitin-conjugating enzyme E2L 60.925
MX1myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)0.906
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.897
IFIT1interferon-induced protein with tetratricopeptide repeats 10.886
SMAD4SMAD family member 40.883
MX2myxovirus (influenza virus) resistance 2 (mouse)0.883
SMAD5SMAD family member 50.882
ATG12ATG12 autophagy related 12 homolog (S. cerevisiae)0.882
CXCL10chemokine (C-X-C motif) ligand 100.881
SMAD2SMAD family member 20.857
DTX3Ldeltex 3-like (Drosophila)0.857
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.850
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.844
CXCL9chemokine (C-X-C motif) ligand 90.842
CXCL2chemokine (C-X-C motif) ligand 20.836
XAF1XIAP associated factor 10.836
HDAC1histone deacetylase 10.809
OASL2'-5'-oligoadenylate synthetase-like0.803
PARP9poly (ADP-ribose) polymerase family, member 90.803
IFIT2interferon-induced protein with tetratricopeptide repeats 20.801
SP100SP100 nuclear antigen0.779
BCL2L1BCL2-like 10.766
HIPK2homeodomain interacting protein kinase 20.762
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.744
TRIM21tripartite motif containing 210.736
IFI6interferon, alpha-inducible protein 60.720
THOC2THO complex 20.715
CXCL11chemokine (C-X-C motif) ligand 110.711
IL8interleukin 80.705
IRF9interferon regulatory factor 90.696
CXCL3chemokine (C-X-C motif) ligand 30.692
SMAD7SMAD family member 70.691
CREBBPCREB binding protein0.686
ISG15ISG15 ubiquitin-like modifier0.677
RSAD2radical S-adenosyl methionine domain containing 20.660
IFIH1interferon induced with helicase C domain 10.647
CCL5chemokine (C-C motif) ligand 50.635
GBP1guanylate binding protein 1, interferon-inducible0.628
STAMBPSTAM binding protein0.628
FHL2four and a half LIM domains 20.624
CCL8chemokine (C-C motif) ligand 80.608
AXLAXL receptor tyrosine kinase0.603
IRF7interferon regulatory factor 70.603
HDGFhepatoma-derived growth factor0.602
SKILSKI-like oncogene0.575
MAPK8mitogen-activated protein kinase 80.574
IGF1Rinsulin-like growth factor 1 receptor0.555
RNF5ring finger protein 50.548
OAS32'-5'-oligoadenylate synthetase 3, 100kDa0.535
SAMD9sterile alpha motif domain containing 90.532
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.523
TSG101tumor susceptibility gene 1010.509
NCBP1nuclear cap binding protein subunit 1, 80kDa0.505
CCR5chemokine (C-C motif) receptor 50.502
THOC1THO complex 10.497
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.494
IRF1interferon regulatory factor 10.491
ATF3activating transcription factor 30.489
PVRL4poliovirus receptor-related 40.475
HDAC2histone deacetylase 20.471
PDCD6programmed cell death 60.463
TNFAIP3tumor necrosis factor, alpha-induced protein 30.459
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.445
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.437
IFI16interferon, gamma-inducible protein 160.433
GOLGA2golgin A20.423
TRIM63tripartite motif containing 630.421
BST2bone marrow stromal cell antigen 20.418
PARP14poly (ADP-ribose) polymerase family, member 140.417
ARID1BAT rich interactive domain 1B (SWI1-like)0.415
PARP12poly (ADP-ribose) polymerase family, member 120.411
ARID1AAT rich interactive domain 1A (SWI-like)0.410
VCAM1vascular cell adhesion molecule 10.409
HNF4Ahepatocyte nuclear factor 4, alpha0.407
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.403
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.395
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
dnc-4Protein DNC-40.173
attf-2Protein ATTF-20.156
unc-37Protein UNC-370.055
C29F5.1Protein C29F5.10.053
bre-5Protein BRE-50.050
CELE_B0285.3Protein B0285.30.047
lmn-1Protein LMN-10.047
hrp-1Protein HRP-10.043
gsp-1Protein GSP-10.037
bmk-1Protein BMK-10.036
CELE_Y57G11C.3Protein Y57G11C.30.035
T07D1.2Protein T07D1.20.033
K10C8.3Protein K10C8.30.031
swsn-3Protein SWSN-30.026
bus-18Protein BUS-180.026
trap-1Protein TRAP-10.026
CELE_Y41E3.7Protein Y41E3.70.025
dnj-12Protein DNJ-120.024
ceh-18Protein CEH-180.022
lsm-5Protein LSM-50.022
lin-13Protein LIN-130.017
atg-9Protein ATG-90.017
efk-1Protein EFK-10.016
daf-1Protein DAF-10.016
nhr-49Protein NHR-490.016
elt-2Protein ELT-20.015
ire-1Protein IRE-10.014
goa-1Protein GOA-10.014
cyn-15Protein CYN-150.014
dnj-11Protein DNJ-110.014
sel-8Protein SEL-80.013
pry-1Protein PRY-10.013
lin-35Protein LIN-350.013
egl-44Protein EGL-440.013
daf-11Protein DAF-110.013
F26F4.8Protein F26F4.80.012
D1081.8Protein D1081.80.012
aipl-1Protein AIPL-10.012
aip-1Protein AIP-10.012
fat-2Protein FAT-20.012
C13C4.5Protein C13C4.50.011
drap-1Protein DRAP-10.011
efl-1Protein EFL-10.011
dnj-19Protein DNJ-190.011
alx-1Protein ALX-10.010
cept-1Protein CEPT-10.010
pqn-65Protein PQN-650.010
rsp-1Protein RSP-10.010
rnp-7Protein RNP-70.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pkzprotein kinase containing Z-DNA binding domains0.208
tcf12transcription factor 120.147
cxcr4bchemokine (C-X-C motif), receptor 4b0.116
tm9sf2transmembrane 9 superfamily member 20.114
insrbinsulin receptor b0.098
mbtps1membrane-bound transcription factor protease, site 10.093
ifnphi1interferon phi 10.091
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.090
tp53tumor protein p530.090
chmp4bchromatin modifying protein 4B0.087
pglyrp5peptidoglycan recognition protein 50.082
ctsbacathepsin B, a0.078
itgb3bintegrin beta 3b0.074
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.072
nod1nucleotide-binding oligomerization domain containing 10.069
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.068
srsf2serine/arginine-rich splicing factor 20.066
furinbfurin (paired basic amino acid cleaving enzyme) b0.063
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.063
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.062
tgfbr2transforming growth factor, beta receptor II0.059
lass2LAG1 homolog, ceramide synthase 2 (S. cerevisiae)0.057
rhogbras homolog gene family, member Gb0.056
dhx15DEAH (Asp-Glu-Ala-His) box polypeptide 150.054
tlr9toll-like receptor 90.053
defbl3defensin, beta-like 30.053
gdf6agrowth differentiation factor 6a0.052
ripk2receptor-interacting serine-threonine kinase 20.051
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.051
xbp1X-box binding protein 10.050
tlr22toll-like receptor 220.050
nos2anitric oxide synthase 2a, inducible0.049
grnagranulin a0.049
stc1lstanniocalcin 1, like0.048
rspo1R-spondin homolog (Xenopus laevis)0.048
plauaplasminogen activator, urokinase a0.048
angptl3angiopoietin-like 30.047
luc7lLUC7-like (S. cerevisiae)0.046
junbljun B proto-oncogene, like0.045
tlr21toll-like receptor 210.045
spry4sprouty (Drosophila) homolog 40.045
prpf8pre-mRNA processing factor 80.044
defbl1defensin, beta-like 10.043
pcsk5bproprotein convertase subtilisin/kexin type 5b0.043
il1binterleukin 1, beta and interleukin 1, beta0.043
maffv-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)0.043
itln3intelectin 30.042
cdk7cyclin-dependent kinase 70.042
sfrs3bsplicing factor, arginine/serine-rich 3b0.042
ppp4caprotein phosphatase 4 (formerly X), catalytic subunit a0.042
stat1bsignal transducer and activator of transcription 1b0.042
hnrnph1lheterogeneous nuclear ribonucleoprotein H1, like0.041
nup107nucleoporin 1070.041
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.041
eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.041
cmybtranscription factor cmyb0.041
wnt3wingless-type MMTV integration site family, member 30.040
ube2iubiquitin-conjugating enzyme E2I0.040
ticam1toll-like receptor adaptor molecule 10.040
pcsk7proprotein convertase subtilisin/kexin type 70.040
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.039
sdf4stromal cell derived factor 40.039
itln1intelectin 10.039
nup50nucleoporin 500.039
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.039
ahctf1AT hook containing transcription factor 10.038
robo4roundabout homolog 40.038
angptl2angiopoietin-like 20.038
ptenaphosphatase and tensin homolog A0.038
tax1bp1bTax1 (human T-cell leukemia virus type I) binding protein 1b0.038
mmp13amatrix metalloproteinase 13a0.038
hdac4histone deacetylase 40.038
LOC100000934hypothetical protein LOC1000009340.038
insl5binsulin-like 5b0.037
cxcr3.2chemokine (C-X-C motif) receptor 3.20.037
LOC100004946transient receptor potential cation channel subfamily M member 4-like0.037
lama1laminin, alpha 10.037
LOC566020Gig2-like protein DreO0.037
tpd52l2atumor protein D52-like 2a0.037
irx5airoquois homeobox protein 5a0.037
sult3st1sulfotransferase family 3, cytosolic sulfotransferase 10.036
LOC557072caspase recruitment domain-containing protein 11-like0.036
card9caspase recruitment domain family, member 90.036
nr0b1nuclear receptor subfamily 0, group B, member 10.035
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.035
hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.035
tm4sf4transmembrane 4 L six family member 40.035
stilTAL1 (SCL) interrupting locus0.035
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.034
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
vps2CG14542 gene product from transcript CG14542-RA0.754
vps24Charged multivesicular body protein 30.410
Pi3K92ECG4141 gene product from transcript CG4141-RB0.294
StimStromal interaction molecule0.290
CG10103CG10103 gene product from transcript CG10103-RA0.264
sqhspaghetti squash0.228
CHMP2BCharged multivesicular body protein 2b0.217
Stat92ESignal-transducer and activator of transcription protein at 92E0.128
CG32810CG32810 gene product from transcript CG32810-RB0.125
Atg1Autophagy-specific gene 10.124
upd3unpaired 30.123
CG6259CG6259 gene product from transcript CG6259-RA0.085
Chmp1CG4108 gene product from transcript CG4108-RA0.066
Atg18Autophagy-specific gene 180.063
rheaCG6831 gene product from transcript CG6831-RA0.058
Cyp316a1CG8540 gene product from transcript CG8540-RA0.058
CG9184CG9184 gene product from transcript CG9184-RB0.054
StamSignal transducing adaptor molecule0.052
CSN4COP9 complex homolog subunit 40.048
CG8108CG8108 gene product from transcript CG8108-RA0.045
PGRP-SC1bCG8577 gene product from transcript CG8577-RA0.044
CG18594CG18594 gene product from transcript CG18594-RA0.042
CG17244CG17244 gene product from transcript CG17244-RA0.035
Ork1Open rectifier K[+] channel 10.034
Letm1CG4589 gene product from transcript CG4589-RB0.033
CG14526CG14526 gene product from transcript CG14526-RB0.033
EcREcdysone receptor0.032
MadMothers against dpp0.030
GNBP3Gram-negative bacteria binding protein 30.030
CG9990CG9990 gene product from transcript CG9990-RA0.030
CG4699CG4699 gene product from transcript CG4699-RJ0.029
iclnCG4924 gene product from transcript CG4924-RA0.029
SpargelCG9809 gene product from transcript CG9809-RB0.028
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.027
CG13795CG13795 gene product from transcript CG13795-RB0.027
Or22aOdorant receptor 22a0.027
Arf72AArflike at 72A0.027
G-salpha60AG protein salpha 60A0.027
CG4822CG4822 gene product from transcript CG4822-RB0.027
CG3164CG3164 gene product from transcript CG3164-RA0.026
LanB2Laminin B20.025
hydhyperplastic discs0.024
MtpMicrosomal triacylglycerol transfer protein0.024
sec15CG7034 gene product from transcript CG7034-RA0.024
CG1092CG1092 gene product from transcript CG1092-RA0.023
Atg4Autophagy-specific gene 40.022
Ufd1-likeUbiquitin fusion-degradation 1-like0.022
CG6426CG6426 gene product from transcript CG6426-RA0.022
CG7967CG7967 gene product from transcript CG7967-RA0.022
htshu li tai shao0.022
CG5273CG5273 gene product from transcript CG5273-RA0.022
CG7997CG7997 gene product from transcript CG7997-RB0.021
cbscentrosomin's beautiful sister0.021
CG6910CG6910 gene product from transcript CG6910-RB0.021
Ten-mTenascin major0.021
Fkbp13CG9847 gene product from transcript CG9847-RC0.020
CstF-50CG2261 gene product from transcript CG2261-RA0.020
Rab2Rab-protein 20.020
McrMacroglobulin complement-related0.020
CG3775CG3775 gene product from transcript CG3775-RA0.020
CG18249CG18249 gene product from transcript CG18249-RB0.019
AcerAngiotensin-converting enzyme-related0.019
Atg9Autophagy-specific gene 90.019
ird5immune response deficient 50.019
ird1immune response deficient 10.019
Npc2gNiemann-Pick type C-2g0.019
eIF-1AEukaryotic initiation factor 1A0.019
Mgat1UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I0.019
CG9339CG9339 gene product from transcript CG9339-RG0.019
Vps28Vacuolar protein sorting 280.019
CG3918CG3918 gene product from transcript CG3918-RA0.018
nudCCG9710 gene product from transcript CG9710-RA0.018
CG4968CG4968 gene product from transcript CG4968-RA0.018
RanBPMRan-binding protein M0.018
tbcetubulin-specific chaperone E0.018
CG8600CG8600 gene product from transcript CG8600-RB0.017
Ranbp11CG33139 gene product from transcript CG33139-RA0.017
CG2736CG2736 gene product from transcript CG2736-RA0.017
Sin3ACG8815 gene product from transcript CG8815-RC0.017
Socs36ESuppressor of cytokine signaling at 36E0.017
CG33307CG33307 gene product from transcript CG33307-RA0.017
Rpn9CG10230 gene product from transcript CG10230-RB0.017
Vps4Vacuolar protein sorting 40.017
ImpIGF-II mRNA-binding protein0.017
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trim30atripartite motif-containing 30A0.996
Casp4caspase 4, apoptosis-related cysteine peptidase0.995
Irf7interferon regulatory factor 70.991
Parp14poly (ADP-ribose) polymerase family, member 140.984
Oasl22'-5' oligoadenylate synthetase-like 20.983
Rsad2radical S-adenosyl methionine domain containing 20.981
Irf9interferon regulatory factor 90.975
Uba7ubiquitin-like modifier activating enzyme 70.975
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.969
Rtp4receptor transporter protein 40.962
Dhx58DEXH (Asp-Glu-X-His) box polypeptide 580.961
Usp18ubiquitin specific peptidase 180.956
Irf1interferon regulatory factor 10.954
TapbpTAP binding protein0.951
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.949
Irgm2immunity-related GTPase family M member 20.947
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.945
Ccl2chemokine (C-C motif) ligand 20.944
Gbp7guanylate binding protein 70.943
Ifi44interferon-induced protein 440.941
Ifitm3interferon induced transmembrane protein 30.930
Cd44CD44 antigen0.921
Zbp1Z-DNA binding protein 10.906
Tnftumor necrosis factor0.898
Tlr4toll-like receptor 40.888
Irgm1immunity-related GTPase family M member 10.885
Stat1signal transducer and activator of transcription 10.872
Casp1caspase 10.872
Il10interleukin 100.862
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.832
Cd19CD19 antigen0.826
Unc93b1unc-93 homolog B1 (C. elegans)0.816
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.816
Myd88myeloid differentiation primary response gene 880.811
Ifit3interferon-induced protein with tetratricopeptide repeats 30.806
Tor3atorsin family 3, member A0.806
Ifi35interferon-induced protein 350.792
Ifit1interferon-induced protein with tetratricopeptide repeats 10.784
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.783
Oasl12'-5' oligoadenylate synthetase-like 10.775
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.770
Stat2signal transducer and activator of transcription 20.764
Socs1suppressor of cytokine signaling 10.759
Trp53transformation related protein 530.756
Slfn4schlafen 40.751
Trim21tripartite motif-containing 210.743
Nos2nitric oxide synthase 2, inducible0.741
Cxcl10chemokine (C-X-C motif) ligand 100.740
Oas32'-5' oligoadenylate synthetase 30.734
Igtpinterferon gamma induced GTPase0.722
BC006779cDNA sequence BC0067790.718
Parp10poly (ADP-ribose) polymerase family, member 100.713
PycardPYD and CARD domain containing0.711
Oas1a2'-5' oligoadenylate synthetase 1A0.707
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.704
Ctsgcathepsin G0.704
Aim2absent in melanoma 20.700
Mx2myxovirus (influenza virus) resistance 20.700
Ifih1interferon induced with helicase C domain 10.699
Parp9poly (ADP-ribose) polymerase family, member 90.684
Mx1myxovirus (influenza virus) resistance 10.683
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.683
Trim25tripartite motif-containing 250.638
Gbp2guanylate binding protein 20.630
Oas22'-5' oligoadenylate synthetase 20.603
Cmpk2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial0.598
Tnfsf10tumor necrosis factor (ligand) superfamily, member 100.596
Gbp3guanylate binding protein 30.593
Isg15ISG15 ubiquitin-like modifier0.581
Bcl2B-cell leukemia/lymphoma 20.569
Csf1colony stimulating factor 1 (macrophage)0.569
Ifnginterferon gamma0.564
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.535
Atg12autophagy-related 12 (yeast)0.514
Trim34atripartite motif-containing 34A0.502
Iigp1interferon inducible GTPase 10.501
Mndalmyeloid nuclear differentiation antigen like0.501
Ngpneutrophilic granule protein0.499
Gm12185predicted gene 121850.498
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.483
BaxBCL2-associated X protein0.479
Tnfaip3tumor necrosis factor, alpha-induced protein 30.477
Campcathelicidin antimicrobial peptide0.475
FaslFas ligand (TNF superfamily, member 6)0.472
Ltalymphotoxin A0.464
Gzmbgranzyme B0.438
Bst2bone marrow stromal cell antigen 20.433
Ifi47interferon gamma inducible protein 470.425
Herc6hect domain and RLD 60.417
Ccl5chemokine (C-C motif) ligand 50.412
Ube2l6ubiquitin-conjugating enzyme E2L 60.412
Cxcl2chemokine (C-X-C motif) ligand 20.407
Ifi27l2ainterferon, alpha-inducible protein 27 like 2A0.401
Cxcr5chemokine (C-X-C motif) receptor 50.401
D14Ertd668eDNA segment, Chr 14, ERATO Doi 668, expressed0.398
Trim30dtripartite motif-containing 30D0.398
Ptgs2prostaglandin-endoperoxide synthase 20.394
Fcgr1Fc receptor, IgG, high affinity I0.386
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism