The network for 'centromeric sister chromatid cohesion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

centromeric sister chromatid cohesion

The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.

NameDescriptionProbabilityFunc Analog Organism
ANAPC4anaphase promoting complex subunit 40.644
CDC27cell division cycle 27 homolog (S. cerevisiae)0.495
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.384
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.361
CDC20cell division cycle 20 homolog (S. cerevisiae)0.337
CASC5cancer susceptibility candidate 50.224
APCadenomatous polyposis coli0.200
CTNNBIP1catenin, beta interacting protein 10.179
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.157
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.140
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.082
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.080
GSK3Bglycogen synthase kinase 3 beta0.065
AXIN1axin 10.053
NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.045
CENPEcentromere protein E, 312kDa0.040
CSNK1Ecasein kinase 1, epsilon0.038
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.036
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.029
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.021
FBXO5F-box protein 50.019
EMDemerin0.017
NAA15N(alpha)-acetyltransferase 15, NatA auxiliary subunit0.017
JUPjunction plakoglobin0.016
SMAD7SMAD family member 70.015
WDYHV1WDYHV motif containing 10.013
ZWINTZW10 interactor0.013
MAD1L1MAD1 mitotic arrest deficient-like 1 (yeast)0.012
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.012
GLIS2GLIS family zinc finger 20.011
TCF4transcription factor 40.011
TTKTTK protein kinase0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
glglass0.020
atoatonal0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Apcadenomatosis polyposis coli0.884
Ctnnb1catenin (cadherin associated protein), beta 10.805
Gsk3bglycogen synthase kinase 3 beta0.791
Fgfr2fibroblast growth factor receptor 20.373
Ptenphosphatase and tensin homolog0.333
Smad3MAD homolog 3 (Drosophila)0.285
Rnf111ring finger 1110.229
Trp53transformation related protein 530.225
Axin1axin 10.134
Lrp6low density lipoprotein receptor-related protein 60.103
Rac1RAS-related C3 botulinum substrate 10.077
Fgfr1fibroblast growth factor receptor 10.070
Lrp5low density lipoprotein receptor-related protein 50.070
Prc1protein regulator of cytokinesis 10.070
Htthuntingtin0.060
Shhsonic hedgehog0.054
Lef1lymphoid enhancer binding factor 10.053
Ptpn11protein tyrosine phosphatase, non-receptor type 110.052
Cenpncentromere protein N0.052
Smad7MAD homolog 7 (Drosophila)0.052
Smad2MAD homolog 2 (Drosophila)0.051
Cenpecentromere protein E0.050
Smad4MAD homolog 4 (Drosophila)0.049
Bmpr1abone morphogenetic protein receptor, type 1A0.043
Stat3signal transducer and activator of transcription 30.043
Kitkit oncogene0.038
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.034
Birc5baculoviral IAP repeat-containing 50.033
Psen1presenilin 10.033
Ctnna1catenin (cadherin associated protein), alpha 10.032
Cenphcentromere protein H0.031
Smad6MAD homolog 6 (Drosophila)0.031
Bmp4bone morphogenetic protein 40.030
Ccnd1cyclin D10.028
Notch1Notch gene homolog 1 (Drosophila)0.026
Cdh1cadherin 10.024
Cenppcentromere protein P0.024
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.023
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.022
Ctnnd1catenin (cadherin associated protein), delta 10.022
Nf2neurofibromatosis 20.022
Itgb1integrin beta 1 (fibronectin receptor beta)0.021
Depdc1bDEP domain containing 1B0.020
Numbnumb gene homolog (Drosophila)0.019
Adam17a disintegrin and metallopeptidase domain 170.019
Vhlvon Hippel-Lindau tumor suppressor0.019
Ctnnbip1catenin beta interacting protein 10.018
Wlswntless homolog (Drosophila)0.018
Lrrk2leucine-rich repeat kinase 20.016
Ccnb2cyclin B20.016
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.016
Tax1bp3Tax1 (human T-cell leukemia virus type I) binding protein 30.015
Plk1polo-like kinase 1 (Drosophila)0.015
Arhgap11aRho GTPase activating protein 11A0.014
Raf1v-raf-leukemia viral oncogene 10.014
Wnt4wingless-related MMTV integration site 40.013
Rararetinoic acid receptor, alpha0.013
Mdm2transformed mouse 3T3 cell double minute 20.013
Mki67antigen identified by monoclonal antibody Ki 670.013
Cbfbcore binding factor beta0.012
Vegfavascular endothelial growth factor A0.012
Esr1estrogen receptor 1 (alpha)0.012
Hes1hairy and enhancer of split 1 (Drosophila)0.011
Ccna2cyclin A20.011
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.011
Itga3integrin alpha 30.011
Hmmrhyaluronan mediated motility receptor (RHAMM)0.011
Spag5sperm associated antigen 50.011
Rxraretinoid X receptor alpha0.011
BrafBraf transforming gene0.011
Hprthypoxanthine guanine phosphoribosyl transferase0.011
Git1G protein-coupled receptor kinase-interactor 10.011
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.010
Ckap2cytoskeleton associated protein 20.010
Esco2establishment of cohesion 1 homolog 2 (S. cerevisiae)0.010
Il6stinterleukin 6 signal transducer0.010
Rb1retinoblastoma 10.010
Shcbp1Shc SH2-domain binding protein 10.010
Cdca8cell division cycle associated 80.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
UBI4Ubi4p0.011