The network for 'negative regulation of cellular protein metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cellular protein metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
RB1retinoblastoma 10.999
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.997
GSK3Bglycogen synthase kinase 3 beta0.997
MAPK14mitogen-activated protein kinase 140.995
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.991
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.990
AKT1v-akt murine thymoma viral oncogene homolog 10.989
MAPK1mitogen-activated protein kinase 10.986
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.986
UBCubiquitin C0.976
EGFRepidermal growth factor receptor0.973
PRKCZprotein kinase C, zeta0.965
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.950
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.919
METmet proto-oncogene (hepatocyte growth factor receptor)0.910
TP53tumor protein p530.906
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.902
SFNstratifin0.898
PLCG1phospholipase C, gamma 10.875
NR4A1nuclear receptor subfamily 4, group A, member 10.873
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.864
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.856
JUNjun proto-oncogene0.847
BCL2B-cell CLL/lymphoma 20.846
PRKCAprotein kinase C, alpha0.845
BCAR1breast cancer anti-estrogen resistance 10.829
DAXXdeath-domain associated protein0.824
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.821
PTPN1protein tyrosine phosphatase, non-receptor type 10.815
CDK4cyclin-dependent kinase 40.815
CASP8caspase 8, apoptosis-related cysteine peptidase0.812
APPamyloid beta (A4) precursor protein0.803
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.798
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.795
BCL2L1BCL2-like 10.794
VIMvimentin0.781
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.779
SHC1SHC (Src homology 2 domain containing) transforming protein 10.779
MTORmechanistic target of rapamycin (serine/threonine kinase)0.773
CUL3cullin 30.769
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.768
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.768
ZNF43zinc finger protein 430.744
CREBBPCREB binding protein0.741
EGR1early growth response 10.736
SMAD3SMAD family member 30.736
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.729
HSPA1Bheat shock 70kDa protein 1B0.727
CDC27cell division cycle 27 homolog (S. cerevisiae)0.724
SMAD7SMAD family member 70.723
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.723
MAP3K7mitogen-activated protein kinase kinase kinase 70.721
DUSP1dual specificity phosphatase 10.720
RICTORRPTOR independent companion of MTOR, complex 20.716
QKIquaking homolog, KH domain RNA binding (mouse)0.712
GHRgrowth hormone receptor0.711
E2F1E2F transcription factor 10.708
TOB1transducer of ERBB2, 10.691
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.681
HNRNPKheterogeneous nuclear ribonucleoprotein K0.676
CTSBcathepsin B0.659
GRB2growth factor receptor-bound protein 20.656
CCND1cyclin D10.655
LCKlymphocyte-specific protein tyrosine kinase0.653
ACTBactin, beta0.644
ZNF273zinc finger protein 2730.640
GABARAPGABA(A) receptor-associated protein0.639
HDAC1histone deacetylase 10.634
MMP14matrix metallopeptidase 14 (membrane-inserted)0.633
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.630
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.627
FYNFYN oncogene related to SRC, FGR, YES0.620
TRIM28tripartite motif containing 280.610
FOSFBJ murine osteosarcoma viral oncogene homolog0.590
ADAM15ADAM metallopeptidase domain 150.590
ARRB1arrestin, beta 10.588
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.586
RPTORregulatory associated protein of MTOR, complex 10.584
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.581
HUWE1HECT, UBA and WWE domain containing 10.581
PARP1poly (ADP-ribose) polymerase 10.578
NR4A2nuclear receptor subfamily 4, group A, member 20.574
HSPA4heat shock 70kDa protein 40.574
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.565
A2Malpha-2-macroglobulin0.564
GRB10growth factor receptor-bound protein 100.564
RARAretinoic acid receptor, alpha0.563
ATF2activating transcription factor 20.555
BIRC2baculoviral IAP repeat containing 20.550
MAP3K5mitogen-activated protein kinase kinase kinase 50.548
MED28mediator complex subunit 280.540
KLF6Kruppel-like factor 60.539
SMAD4SMAD family member 40.532
CNOT8CCR4-NOT transcription complex, subunit 80.531
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.529
WWP2WW domain containing E3 ubiquitin protein ligase 20.529
PABPC1poly(A) binding protein, cytoplasmic 10.529
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.528
TSC2tuberous sclerosis 20.525
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.165
par-5Protein PAR-50.151
mec-2Protein MEC-20.141
F26B1.2Protein F26B1.20.141
egl-44Protein EGL-440.137
imb-2Protein IMB-20.137
mex-5Protein MEX-50.135
ztf-7Protein ZTF-70.132
ntl-4Protein NTL-40.126
brp-1Protein BRP-10.121
unc-53Protein UNC-530.106
tps-1Protein TPS-10.104
sax-3Protein SAX-30.103
F21A10.2Protein F21A10.20.090
gld-1Protein GLD-10.088
CELE_K08F4.2Protein K08F4.20.087
chd-7Protein CHD-70.086
spc-1Protein SPC-10.084
tba-2Protein TBA-20.080
inx-3Protein INX-30.080
C37H5.6Protein C37H5.60.078
vab-3Protein VAB-30.075
tbb-2Protein TBB-20.074
sma-3Protein SMA-30.072
vps-33.2Protein VPS-33.20.068
dgk-2Protein DGK-20.068
hlh-30Protein HLH-300.065
inx-13Protein INX-130.063
dmd-6Protein DMD-60.063
eps-8Protein EPS-80.062
ntl-2Protein NTL-20.061
hum-6Protein HUM-60.060
egl-27Protein EGL-270.059
ubq-1Protein UBQ-10.059
nap-1Protein NAP-10.057
daf-21Protein DAF-210.055
lin-7Protein LIN-70.053
smp-1Protein SMP-10.053
pry-1Protein PRY-10.053
CELE_Y61A9LA.3Protein Y61A9LA.30.051
sma-6Protein SMA-60.050
hpo-32Protein HPO-320.049
rhi-1Protein RHI-10.049
dsh-2Protein DSH-20.047
dnc-1Protein DNC-10.046
ZK512.2Protein ZK512.20.045
alx-1Protein ALX-10.045
egl-8Protein EGL-80.045
F25B3.6Protein F25B3.60.043
his-45Protein HIS-450.042
ajm-1Protein AJM-10.041
skn-1Protein SKN-10.041
dli-1Protein DLI-10.041
atg-2Protein ATG-20.040
nhr-10Protein NHR-100.040
wago-1Protein WAGO-10.040
plk-1Protein PLK-10.040
snr-2Protein SNR-20.040
ptp-3Protein PTP-30.040
gld-2Protein GLD-20.039
ztf-17Protein ZTF-170.039
eif-3.BProtein EIF-3.B0.038
lmn-1Protein LMN-10.037
gpr-1Protein GPR-10.037
C35D10.1Protein C35D10.10.037
ptr-2Protein PTR-20.037
ZK507.6Protein ZK507.60.035
gyg-2Protein GYG-20.035
ify-1Protein IFY-10.035
sym-4Protein SYM-40.034
mex-3Protein MEX-30.034
afd-1Protein AFD-10.034
cpg-2Protein CPG-20.034
F55F8.9Protein F55F8.90.033
cye-1Protein CYE-10.033
stau-1Protein STAU-10.033
B0336.3Protein B0336.30.033
daf-3Protein DAF-30.033
lbp-3Protein LBP-30.032
lars-1Protein LARS-10.032
pat-3Protein PAT-30.032
ife-3Protein IFE-30.032
dlk-1Protein DLK-10.032
atg-9Protein ATG-90.032
cyk-4Protein CYK-40.032
cgh-1Protein CGH-10.031
Y87G2A.1Protein Y87G2A.10.031
B0035.1Protein B0035.10.031
daf-1Protein DAF-10.031
puf-6Protein PUF-60.031
tiar-1Protein TIAR-10.031
zoo-1Protein ZOO-10.031
rrbs-1Protein RRBS-10.030
C13F10.4Protein C13F10.40.030
cpg-1Protein CPG-10.030
CELE_B0334.5Protein B0334.50.030
D1081.9Protein D1081.90.030
nhr-143Protein NHR-1430.029
pde-4Protein PDE-40.029
F49C12.9Protein F49C12.90.029
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ef1aelongation factor 1-alpha0.144
sox9bSRY-box containing gene 9b0.123
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.101
tp53tumor protein p530.099
sema3aasemaphorin 3aa0.097
bcl2l1bcl2-like 10.073
spry4sprouty (Drosophila) homolog 40.059
shhasonic hedgehog a0.059
nf1aneurofibromin 1a0.056
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.050
sox11aSRY-box containing gene 11a0.050
bmp2bbone morphogenetic protein 2b0.048
cdk8cyclin-dependent kinase 80.047
bactin1bactin10.045
pcsk5bproprotein convertase subtilisin/kexin type 5b0.045
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.045
tcf12transcription factor 120.044
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.041
fxr2fragile X mental retardation, autosomal homolog 20.040
hspa4bheat shock protein 4b0.040
furinafurin (paired basic amino acid cleaving enzyme) a0.039
hspa4aheat shock protein 4a0.039
sall1asal-like 1a (Drosophila)0.039
bactin2bactin20.037
usp5ubiquitin specific protease 50.036
pcnaproliferating cell nuclear antigen0.034
cdc20cell division cycle 20 homolog0.033
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.033
ccna2cyclin A20.032
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.032
tgif1TGFB-induced factor homeobox 10.032
lims1LIM and senescent cell antigen-like domains 10.032
pak2ap21 (CDKN1A)-activated kinase 2a0.031
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.030
ccnb1cyclin B10.030
stac3SH3 and cysteine rich domain 30.030
ptgs1prostaglandin-endoperoxide synthase 10.030
zgc:56304zgc:563040.029
dusp6dual specificity phosphatase 60.028
per2period homolog 2 (Drosophila)0.028
fgfr2fibroblast growth factor receptor 20.028
naa15aN(alpha)-acetyltransferase 15, NatA auxiliary subunit a0.027
baxabcl2-associated X protein, a0.027
junjun proto-oncogene0.026
hnrnpkheterogeneous nuclear ribonucleoprotein K0.026
dnmt3DNA (cytosine-5-)-methyltransferase 30.026
stc1lstanniocalcin 1, like0.026
flhfloating head0.025
dag1dystroglycan 10.025
nrg2aneuregulin 2a0.025
lama4laminin, alpha 40.025
zgc:111944zgc:1119440.025
bcl2l10BCL2-like 10 (apoptosis facilitator)0.024
rarabretinoic acid receptor, alpha b0.024
dmddystrophin0.024
rbfox2RNA binding protein, fox-1 homolog (C. elegans) 20.024
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.024
rhoubras homolog gene family, member Ub0.024
elk4ELK4, ETS-domain protein0.023
caprin1acell cycle associated protein 1a0.023
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.022
hs6st1bheparan sulfate 6-O-sulfotransferase 1b0.022
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.022
nclnucleolin0.022
junbjun B proto-oncogene0.022
s1pr1sphingosine-1-phosphate receptor 10.022
trim71tripartite motif-containing 710.022
sox2SRY-box containing gene 20.022
egr1early growth response 10.021
fabp10afatty acid binding protein 10a, liver basic0.021
hsp90a.2heat shock protein 90-alpha 20.021
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.021
neurod4neurogenic differentiation 40.021
tnpo3transportin 30.021
ube2i2ubiquitin-conjugating enzyme E2I20.021
usp10ubiquitin specific peptidase 100.020
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.020
dzip1DAZ interacting protein 10.020
cebpdCCAAT/enhancer binding protein (C/EBP), delta0.020
wu:fi25h02wu:fi25h020.020
tm4sf4transmembrane 4 L six family member 40.020
polr2dpolymerase (RNA) II (DNA directed) polypeptide D0.019
strapserine/threonine kinase receptor associated protein0.019
lcp1lymphocyte cytosolic plastin 10.019
evx1even-skipped homeobox 10.019
prkciprotein kinase C, iota0.019
mstnbmyostatin b0.019
hhiphedgehog interacting protein0.019
sepw1selenoprotein W, 10.019
ntn2netrin 20.019
junbljun B proto-oncogene, like0.019
smad1MAD homolog 1 (Drosophila)0.019
lass2LAG1 homolog, ceramide synthase 2 (S. cerevisiae)0.018
ahsa1lAHA1, activator of heat shock protein ATPase homolog 1, like0.018
gadd45abgrowth arrest and DNA-damage-inducible, alpha, b0.018
kif23kinesin family member 230.018
plp1aproteolipid protein 1a0.018
mbnl2muscleblind-like 2 (Drosophila)0.018
foxi1forkhead box I10.018
axin2axin 2 (conductin, axil)0.018
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Akt1CG4006 gene product from transcript CG4006-RA0.612
drkdownstream of receptor kinase0.573
oskoskar0.570
Src64BSrc oncogene at 64B0.531
EgfrEpidermal growth factor receptor0.523
spispitz0.471
MadMothers against dpp0.451
Su(var)205Suppressor of variegation 2050.413
Tak1TGF-beta activated kinase 10.395
Pi3K92ECG4141 gene product from transcript CG4141-RB0.390
Ras85DRas oncogene at 85D0.334
dncdunce0.321
UbxUltrabithorax0.318
G-oalpha47AG protein oalpha 47A0.298
rlrolled0.263
rinrasputin0.253
shgshotgun0.250
SF2CG6987 gene product from transcript CG6987-RA0.232
AblAbl tyrosine kinase0.226
sxcsuper sex combs0.225
IswiImitation SWI0.224
rapretina aberrant in pattern0.217
smt3CG4494 gene product from transcript CG4494-RA0.215
eghegghead0.215
bchsblue cheese0.192
twstwins0.190
brmbrahma0.190
Hsp83Heat shock protein 830.190
Adf1Adh transcription factor 10.184
rhorhomboid0.180
DadDaughters against dpp0.180
enaenabled0.178
dppdecapentaplegic0.170
thrthree rows0.169
scnyscrawny0.165
Socs36ESuppressor of cytokine signaling at 36E0.163
taitaiman0.163
gishgilgamesh0.163
Hsc70-4Heat shock protein cognate 40.161
htshu li tai shao0.160
lgslegless0.158
simjsimjang0.158
sosine oculis0.155
SmoxSmad on X0.152
PenPendulin0.151
krzkurtz0.151
eyaeyes absent0.149
Uba2Smt3 activating enzyme 20.149
PtenCG5671 gene product from transcript CG5671-RB0.148
rictorrapamycin-insensitive companion of Tor0.138
mtsmicrotubule star0.136
Tao-1CG14217 gene product from transcript CG14217-RF0.134
Nrx-IVNeurexin IV0.132
TspThrombospondin0.131
mirrmirror0.130
Ptp69DProtein tyrosine phosphatase 69D0.126
dapdacapo0.126
msnmisshapen0.125
EndoGIEndonuclease G inhibitor0.125
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.124
tshteashirt0.124
rutrutabaga0.123
bambag of marbles0.122
ThorCG8846 gene product from transcript CG8846-RA0.122
sogshort gastrulation0.122
Galpha49BG protein alpha49B0.120
ththread0.119
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.119
RanBPMRan-binding protein M0.114
gwgawky0.113
NmtN-myristoyl transferase0.112
NFATNFAT homolog0.112
Top1Topoisomerase 10.111
stcksteamer duck0.111
Cdc42CG12530 gene product from transcript CG12530-RA0.110
CycACyclin A0.110
loqsloquacious0.109
KP78bCG17216 gene product from transcript CG17216-RB0.109
stysprouty0.109
CamCalmodulin0.108
Psf2CG18013 gene product from transcript CG18013-RA0.105
ShcSHC-adaptor protein0.104
tkvthickveins0.103
scbscab0.103
kek1kekkon-10.101
swmsecond mitotic wave missing0.099
drprdraper0.098
jingCG9397 gene product from transcript CG9397-RI0.097
CycBCyclin B0.097
Fmr1CG6203 gene product from transcript CG6203-RC0.095
foxoforkhead box, sub-group O0.093
UtxCG5640 gene product from transcript CG5640-RD0.093
amnamnesiac0.092
gammaTub23Cgamma-Tubulin at 23C0.092
Six4CG3871 gene product from transcript CG3871-RA0.092
eEF1deltaCG4912 gene product from transcript CG4912-RB0.091
CG1553CG1553 gene product from transcript CG1553-RA0.090
smosmoothened0.090
rprreaper0.089
poloCG12306 gene product from transcript CG12306-RA0.088
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Ptenphosphatase and tensin homolog1.000
Leprleptin receptor0.980
Ctnnb1catenin (cadherin associated protein), beta 10.979
SkilSKI-like0.972
Ptpn11protein tyrosine phosphatase, non-receptor type 110.970
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.960
Rb1retinoblastoma 10.955
Axin1axin 10.951
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.937
Gsk3bglycogen synthase kinase 3 beta0.937
Pax8paired box gene 80.932
Bcl2B-cell leukemia/lymphoma 20.918
Suz12suppressor of zeste 12 homolog (Drosophila)0.914
Clockcircadian locomotor output cycles kaput0.913
Lyz2lysozyme 20.905
Per2period homolog 2 (Drosophila)0.901
FasFas (TNF receptor superfamily member 6)0.899
Mdm2transformed mouse 3T3 cell double minute 20.893
Retret proto-oncogene0.892
Dusp1dual specificity phosphatase 10.872
Nos1nitric oxide synthase 1, neuronal0.866
Casp4caspase 4, apoptosis-related cysteine peptidase0.863
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.853
Grb2growth factor receptor bound protein 20.848
Apcadenomatosis polyposis coli0.842
JunJun oncogene0.840
CblCasitas B-lineage lymphoma0.825
Stat3signal transducer and activator of transcription 30.821
FosFBJ osteosarcoma oncogene0.794
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.792
Hrhairless0.789
Ptgs2prostaglandin-endoperoxide synthase 20.784
Casp1caspase 10.782
Cry2cryptochrome 2 (photolyase-like)0.778
Cdk4cyclin-dependent kinase 40.776
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.776
Nr4a1nuclear receptor subfamily 4, group A, member 10.771
Shhsonic hedgehog0.764
Arntlaryl hydrocarbon receptor nuclear translocator-like0.764
Gli2GLI-Kruppel family member GLI20.760
Smad3MAD homolog 3 (Drosophila)0.755
Nf2neurofibromatosis 20.750
Egfrepidermal growth factor receptor0.750
Brca1breast cancer 10.747
Kdm2blysine (K)-specific demethylase 2B0.746
BlnkB-cell linker0.744
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.742
Ncoa3nuclear receptor coactivator 30.727
Onecut1one cut domain, family member 10.718
Il1r1interleukin 1 receptor, type I0.708
Myd88myeloid differentiation primary response gene 880.698
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.686
JunbJun-B oncogene0.680
Mdm4transformed mouse 3T3 cell double minute 40.679
Iigp1interferon inducible GTPase 10.677
Rararetinoic acid receptor, alpha0.677
Tcf7l1transcription factor 7-like 1 (T-cell specific, HMG box)0.673
Smad7MAD homolog 7 (Drosophila)0.663
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.642
Tsc1tuberous sclerosis 10.638
FynFyn proto-oncogene0.635
Ghrgrowth hormone receptor0.632
Plcg2phospholipase C, gamma 20.626
Prpf40aPRP40 pre-mRNA processing factor 40 homolog A (yeast)0.620
Nf1neurofibromatosis 10.620
Ascl1achaete-scute complex homolog 1 (Drosophila)0.616
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.613
Nr3c1nuclear receptor subfamily 3, group C, member 10.605
Foxp1forkhead box P10.603
Jak2Janus kinase 20.596
Eif2c2eukaryotic translation initiation factor 2C, 20.595
Nos3nitric oxide synthase 3, endothelial cell0.595
Ctla2bcytotoxic T lymphocyte-associated protein 2 beta0.592
Aim2absent in melanoma 20.586
Tnfaip3tumor necrosis factor, alpha-induced protein 30.585
Vegfavascular endothelial growth factor A0.584
Tekendothelial-specific receptor tyrosine kinase0.576
Mapk8mitogen-activated protein kinase 80.574
Rxraretinoid X receptor alpha0.566
Psen1presenilin 10.562
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.558
Mndalmyeloid nuclear differentiation antigen like0.555
Atmataxia telangiectasia mutated homolog (human)0.555
BrafBraf transforming gene0.552
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.552
Drd2dopamine receptor D20.541
Cd28CD28 antigen0.540
Rarbretinoic acid receptor, beta0.538
Tsc2tuberous sclerosis 20.536
BaxBCL2-associated X protein0.535
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.532
Grb10growth factor receptor bound protein 100.527
Smad1MAD homolog 1 (Drosophila)0.518
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.511
Nlrp3NLR family, pyrin domain containing 30.511
Map3k7mitogen-activated protein kinase kinase kinase 70.509
Btg2B-cell translocation gene 2, anti-proliferative0.507
Neurod4neurogenic differentiation 40.506
Fgfr1fibroblast growth factor receptor 10.493
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
FosFBJ osteosarcoma oncogene0.513
Junbjun B proto-oncogene0.424
Dusp1dual specificity phosphatase 10.370
Egr1early growth response 10.347
Zfp36zinc finger protein 360.313
JunJun oncogene0.216
Nr4a3nuclear receptor subfamily 4, group A, member 30.202
Btg2BTG family, member 20.174
Lgals3lectin, galactoside-binding, soluble, 30.172
Calcrlcalcitonin receptor-like0.144
Nek9NIMA (never in mitosis gene a)- related kinase 90.138
Errfi1ERBB receptor feedback inhibitor 10.136
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.133
Anxa2annexin A20.129
Myo1bmyosin Ib0.117
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.116
Klf9Kruppel-like factor 90.115
Metap2methionyl aminopeptidase 20.109
Nr2f6nuclear receptor subfamily 2, group F, member 60.108
Procprotein C0.108
C9complement component 90.107
Egr2early growth response 20.107
Atf3activating transcription factor 30.106
Jak2Janus kinase 20.104
Hspa1aheat shock 70kD protein 1A0.103
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.102
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.101
Fgfr2fibroblast growth factor receptor 20.100
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.096
Tcfe2atranscription factor E2a0.096
Gja1gap junction protein, alpha 10.096
Adam10ADAM metallopeptidase domain 100.093
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.093
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.086
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.082
Ptgs2prostaglandin-endoperoxide synthase 20.081
Klf4Kruppel-like factor 4 (gut)0.080
Cfbcomplement factor B0.080
Hspa9heat shock protein 90.080
Stip1stress-induced phosphoprotein 10.077
Homer3homer homolog 3 (Drosophila)0.077
Ptch1patched homolog 1 (Drosophila)0.076
Marcksmyristoylated alanine rich protein kinase C substrate0.076
Irs1insulin receptor substrate 10.074
Apohapolipoprotein H (beta-2-glycoprotein I)0.074
Klf12Kruppel-like factor 120.073
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.072
Apoa5apolipoprotein A-V0.072
Ahsgalpha-2-HS-glycoprotein0.071
Apoa2apolipoprotein A-II0.071
Hspb1heat shock protein 10.070
Taok1TAO kinase 10.070
Bmpr1abone morphogenetic protein receptor, type IA0.069
Ptmsparathymosin0.068
Tgoln1trans-golgi network protein0.068
Spp2secreted phosphoprotein 20.068
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.067
Rhobras homolog gene family, member B0.067
Socs3suppressor of cytokine signaling 30.067
Tdo2tryptophan 2,3-dioxygenase0.066
Utrnutrophin0.066
Anxa4annexin A40.066
Gjb3gap junction protein, beta 30.065
LOC299282Serine protease inhibitor0.065
Casp2caspase 20.063
Fgafibrinogen alpha chain0.062
Usf2upstream transcription factor 2, c-fos interacting0.062
Apoeapolipoprotein E0.062
Dnaja4DnaJ (Hsp40) homolog, subfamily A, member 40.061
Lyve1lymphatic vessel endothelial hyaluronan receptor 10.061
Cdx1caudal type homeo box 10.061
Ptger3prostaglandin E receptor 3 (subtype EP3)0.061
Cd63Cd63 molecule0.059
Stat5bsignal transducer and activator of transcription 5B0.059
Gja5gap junction protein, alpha 50.059
Apoa1apolipoprotein A-I0.058
Cckarcholecystokinin A receptor0.058
Rgs14regulator of G-protein signaling 140.057
Dctn1dynactin 10.057
Kng2kininogen 20.057
Klf6Kruppel-like factor 60.057
Nos1nitric oxide synthase 1, neuronal0.057
Cdca3cell division cycle associated 30.056
Arnt2aryl hydrocarbon receptor nuclear translocator 20.056
Tgfbr2transforming growth factor, beta receptor II0.056
Epn1Epsin 10.056
Amhanti-Mullerian hormone0.055
Stat6signal transducer and activator of transcription 60.055
Notch3Notch homolog 3 (Drosophila)0.054
Cngb1cyclic nucleotide gated channel beta 10.054
Klf2Kruppel-like factor 2 (lung)0.054
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.054
Slc15a1solute carrier family 15 (oligopeptide transporter), member 10.053
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.053
Dlg1discs, large homolog 1 (Drosophila)0.053
Rgs1regulator of G-protein signaling 10.053
Obp2bodorant binding protein 2B0.052
Sgk1serum/glucocorticoid regulated kinase 10.052
Nr4a1nuclear receptor subfamily 4, group A, member 10.052
Slfn2schlafen 20.052
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
BCK1Bck1p0.663
PIL1Pil1p0.472
CDC55Cdc55p0.443
PPH21Pph21p0.387
BRE5Bre5p0.358
CDC28Cdc28p0.350
CDC20Cdc20p0.304
STI1Sti1p0.289
SUI3Sui3p0.283
PPH22Pph22p0.269
MAD2Mad2p0.243
SIS1Sis1p0.226
MYO5Myo5p0.199
SPT16Spt16p0.187
KSP1Ksp1p0.184
HTA1Hta1p0.172
CTF13Ctf13p0.172
DHH1Dhh1p0.168
BOI1Boi1p0.155
STE20Ste20p0.154
REG1Reg1p0.150
RTS1Rts1p0.144
PLC1Plc1p0.143
CKB1Ckb1p0.141
MAD3Mad3p0.123
SIC1Sic1p0.120
DEF1Def1p0.116
IPL1Ipl1p0.113
SSA1Ssa1p0.112
SUS1Sus1p0.110
PAN1Pan1p0.104
SDS22Sds22p0.098
NPL3Npl3p0.094
FAB1Fab1p0.091
KEM1Kem1p0.090
CAK1Cak1p0.089
CSE4Cse4p0.088
SLI15Sli15p0.087
SGV1Sgv1p0.086
CDC37Cdc37p0.086
MLP2Mlp2p0.086
CPR6Cpr6p0.084
CDC6Cdc6p0.084
CTI6Cti6p0.082
ADR1Adr1p0.080
HHF2Hhf2p0.078
TIF1Tif1p0.078
SSC1Ssc1p0.078
INP53Inp53p0.076
TCP1Tcp1p0.076
DED1Ded1p0.075
SNF1Snf1p0.074
CLB3Clb3p0.073
TPD3Tpd3p0.073
MPT5Mpt5p0.072
TIF4632Tif4632p0.071
SRO9Sro9p0.070
UBR2Ubr2p0.069
GLC7Glc7p0.068
SWE1Swe1p0.068
ESS1Ess1p0.066
RPS9BRps9bp0.066
BUB1Bub1p0.066
SPT15Spt15p0.064
KIP1Kip1p0.064
BUB3Bub3p0.064
NBL1Nbl1p0.063
DAM1Dam1p0.063
RIF1Rif1p0.062
ROM2Rom2p0.062
YBP2Ybp2p0.062
DCP2Dcp2p0.062
VHS3Vhs3p0.061
URN1Urn1p0.060
SLT2Slt2p0.060
SGT1Sgt1p0.059
MDH1Mdh1p0.059
MTW1Mtw1p0.059
PSY4Psy4p0.059
SPT6Spt6p0.057
SOK1Sok1p0.057
STE4Ste4p0.057
PBS2Pbs2p0.057
RRP1Rrp1p0.057
SLK19Slk19p0.057
PAM1Pam1p0.056
HTB1Htb1p0.056
SMC2Smc2p0.056
CHL4Chl4p0.056
YME1Yme1p0.055
SFI1Sfi1p0.055
DRS1Drs1p0.055
GLG2Glg2p0.054
CYC8Cyc8p0.054
TSR1Tsr1p0.054
BRX1Brx1p0.054
GBP2Gbp2p0.054
MKS1Mks1p0.053
PXA1Pxa1p0.053
IMP2'Imp2'p0.052