The network for 'mesenchymal cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mesenchymal cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.

NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 20.999
FGF1fibroblast growth factor 1 (acidic)0.733
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.647
NRP1neuropilin 10.512
BMPR1Abone morphogenetic protein receptor, type IA0.463
INSRinsulin receptor0.328
BMP2bone morphogenetic protein 20.214
FGF10fibroblast growth factor 100.179
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.113
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.110
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.109
GRB10growth factor receptor-bound protein 100.096
SHC2SHC (Src homology 2 domain containing) transforming protein 20.068
PLCG1phospholipase C, gamma 10.064
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.061
JUPjunction plakoglobin0.061
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide0.051
FSTL1follistatin-like 10.048
APPamyloid beta (A4) precursor protein0.037
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.033
FGFR1fibroblast growth factor receptor 10.031
FGF7fibroblast growth factor 70.031
BMP1bone morphogenetic protein 10.024
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.021
MAXMYC associated factor X0.021
CABLES1Cdk5 and Abl enzyme substrate 10.020
CDH5cadherin 5, type 2 (vascular endothelium)0.018
PDGFCplatelet derived growth factor C0.018
SIRT1sirtuin 10.017
SMAD3SMAD family member 30.016
IGF1Rinsulin-like growth factor 1 receptor0.016
ZFYVE9zinc finger, FYVE domain containing 90.016
IRS2insulin receptor substrate 20.015
HOXD9homeobox D90.014
SMAD7SMAD family member 70.013
EGFRepidermal growth factor receptor0.012
FZD1frizzled homolog 1 (Drosophila)0.012
FGF8fibroblast growth factor 8 (androgen-induced)0.012
FCN2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)0.011
LRP6low density lipoprotein receptor-related protein 60.011
CAPRIN2caprin family member 20.011
TGFB1transforming growth factor, beta 10.011
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.010
FGF2fibroblast growth factor 2 (basic)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
dlx5adistal-less homeobox gene 5a0.915
bmp2abone morphogenetic protein 2a0.815
nkx3.2NK3 homeobox 20.735
bmp4bone morphogenetic protein 40.733
foxi1forkhead box I10.661
tbx1T-box 10.652
bmp7bbone morphogenetic protein 7b0.613
bocbrother of CDO0.603
sulf1sulfatase 10.595
bmp2bbone morphogenetic protein 2b0.559
shhasonic hedgehog a0.539
rargaretinoic acid receptor gamma a0.530
fgf10afibroblast growth factor 10a0.514
edn1endothelin 10.512
col2a1acollagen type II, alpha-1a0.511
fgfrl1afibroblast growth factor receptor-like 1a0.487
nkx2.3NK2 transcription factor related 30.456
runx2brunt-related transcription factor 2b0.443
tcf7transcription factor 7 (T-cell specific, HMG-box)0.438
sparcsecreted acidic cysteine rich glycoprotein0.432
dlx3bdistal-less homeobox gene 3b0.425
foxa1forkhead box A10.420
satb2SATB homeobox 20.397
lhx2bLIM homeobox 2b0.397
cdoncell adhesion molecule-related/down-regulated by oncogenes0.377
grem2gremlin 2, cysteine knot superfamily0.369
prrx1apaired related homeobox 1a0.353
ptch1patched 10.351
fgf3fibroblast growth factor 30.339
hoxd4ahomeo box D4a0.336
wnt9awingless-type MMTV integration site family, member 9A0.319
dlx2adistal-less homeobox gene 2a0.316
nkx2.1aNK2 homeobox 1a0.304
fzd7afrizzled homolog 7a0.291
fn1fibronectin 10.286
myod1myogenic differentiation 10.280
mab21l2mab-21-like 20.271
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.268
wnt9bwingless-type MMTV integration site family, member 9B0.260
cdh1cadherin 1, epithelial0.244
pcdh18bprotocadherin 18b0.240
acvr1lactivin A receptor, type I like0.232
barx1BarH-like homeobox 10.228
fli1afriend leukemia integration 1a0.221
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.214
fgfr4fibroblast growth factor receptor 40.213
six4bsine oculis homeobox homolog 4b0.211
osr2odd-skipped related 2 (Drosophila)0.209
nkx2.5NK2 transcription factor related 50.205
ihhaIndian hedgehog homolog a0.196
tbx5aT-box 5a0.190
jag1bjagged 1b0.186
gli1GLI-Kruppel family member 10.186
fgfrl1bfibroblast growth factor receptor-like 1b0.178
dlx6adistal-less homeobox gene 6a0.169
notch2notch homolog 20.166
zfp36l1azinc finger protein 36, C3H type-like 1a0.166
slit3slit (Drosophila) homolog 30.164
ndr2nodal-related 20.157
wif1wnt inhibitory factor 10.155
col8a1acollagen, type VIII, alpha 1a0.150
acvr2bactivin receptor IIb0.147
tgfb2transforming growth factor, beta 20.140
wnt5bwingless-type MMTV integration site family, member 5b0.139
sema3aasemaphorin 3aa0.138
tp53bp2tumor protein p53 binding protein, 20.137
oprd1bopioid receptor, delta 1b0.136
lamb1alaminin, beta 1a0.134
tbx2aT-box gene 2a0.133
ptgs1prostaglandin-endoperoxide synthase 10.132
hand2heart and neural crest derivatives expressed transcript 20.129
pmp22aperipheral myelin protein 22a0.127
irx5airoquois homeobox protein 5a0.120
gli3GLI-Kruppel family member GLI30.120
pdlim7PDZ and LIM domain 70.116
bmp3bone morphogenetic protein 30.114
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.111
hey1hairy/enhancer-of-split related with YRPW motif 10.109
cdx1bcaudal type homeobox 1 b0.108
dlx4adistal-less homeobox gene 4a0.106
tbx15T-box 150.106
pax9paired box gene 90.104
wlswntless homolog (Drosophila)0.104
fras1Fraser syndrome 10.098
dccdeleted in colorectal carcinoma0.097
emp2epithelial membrane protein 20.096
hoxa13bhomeo box A13b0.095
eya1eyes absent homolog 10.094
lama5laminin, alpha 50.094
spry1sprouty homolog 1 (Drosophila)0.094
foxa2forkhead box A20.093
hoxc4ahomeo box C4a0.092
pitx3paired-like homeodomain transcription factor 30.091
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.090
pcdh8protocadherin 80.088
sept7bseptin 7b0.088
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pax3paired box gene 31.000
Fgfr2fibroblast growth factor receptor 20.999
Tbx3T-box 30.999
Gli3GLI-Kruppel family member GLI30.999
Bmp4bone morphogenetic protein 40.998
Gli2GLI-Kruppel family member GLI20.997
Pitx1paired-like homeodomain transcription factor 10.989
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.986
Otx2orthodenticle homolog 2 (Drosophila)0.982
Meox2mesenchyme homeobox 20.979
Ror2receptor tyrosine kinase-like orphan receptor 20.972
Gscgoosecoid homeobox0.959
Fgf10fibroblast growth factor 100.954
Tgfb2transforming growth factor, beta 20.949
Prrx2paired related homeobox 20.949
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.946
Nr5a1nuclear receptor subfamily 5, group A, member 10.939
Fgf8fibroblast growth factor 80.934
Prrx1paired related homeobox 10.929
Alx4aristaless-like homeobox 40.913
Bmp7bone morphogenetic protein 70.904
Pax2paired box gene 20.899
Pitx2paired-like homeodomain transcription factor 20.887
Fgfr1fibroblast growth factor receptor 10.873
Smad6MAD homolog 6 (Drosophila)0.870
Ascl1achaete-scute complex homolog 1 (Drosophila)0.855
Wnt3awingless-related MMTV integration site 3A0.834
Ptenphosphatase and tensin homolog0.833
Twist2twist homolog 2 (Drosophila)0.813
Tgfbr2transforming growth factor, beta receptor II0.812
Sox2SRY-box containing gene 20.804
Msx1homeobox, msh-like 10.790
Foxc1forkhead box C10.788
Foxc2forkhead box C20.785
Dkk1dickkopf homolog 1 (Xenopus laevis)0.783
Acvr1activin A receptor, type 10.777
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.776
Zeb1zinc finger E-box binding homeobox 10.773
Sox9SRY-box containing gene 90.734
Hoxa1homeobox A10.727
Nos3nitric oxide synthase 3, endothelial cell0.721
Twist1twist homolog 1 (Drosophila)0.698
Ptch1patched homolog 10.693
Trp53transformation related protein 530.692
Sox7SRY-box containing gene 70.692
Tbx2T-box 20.664
Apcadenomatosis polyposis coli0.658
Smad4MAD homolog 4 (Drosophila)0.634
Kdrkinase insert domain protein receptor0.605
Fgfr3fibroblast growth factor receptor 30.601
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.590
Gbx2gastrulation brain homeobox 20.588
Lhx1LIM homeobox protein 10.578
Hoxd13homeobox D130.573
Zic3zinc finger protein of the cerebellum 30.571
Emx2empty spiracles homolog 2 (Drosophila)0.570
Tbx1T-box 10.562
Vegfavascular endothelial growth factor A0.558
Flt4FMS-like tyrosine kinase 40.547
Foxf1aforkhead box F1a0.535
Vangl2vang-like 2 (van gogh, Drosophila)0.529
Gdf5growth differentiation factor 50.525
Lrp6low density lipoprotein receptor-related protein 60.507
Lhx3LIM homeobox protein 30.493
Dlx5distal-less homeobox 50.491
Lef1lymphoid enhancer binding factor 10.484
Gata4GATA binding protein 40.477
Pax6paired box gene 60.474
Retret proto-oncogene0.448
Npr3natriuretic peptide receptor 30.444
Hoxa11homeobox A110.433
Tbx15T-box 150.425
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.417
En1engrailed 10.415
Neurog2neurogenin 20.414
Hoxa13homeobox A130.407
Ptprbprotein tyrosine phosphatase, receptor type, B0.393
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.388
Kiss1KiSS-1 metastasis-suppressor0.385
Wnt5awingless-related MMTV integration site 5A0.366
Pou3f3POU domain, class 3, transcription factor 30.364
Ctnnb1catenin (cadherin associated protein), beta 10.358
Smad3MAD homolog 3 (Drosophila)0.346
Hes1hairy and enhancer of split 1 (Drosophila)0.340
Pax9paired box gene 90.335
Alx1ALX homeobox 10.335
Gas1growth arrest specific 10.320
Snai1snail homolog 1 (Drosophila)0.316
Fgf18fibroblast growth factor 180.316
Hoxd11homeobox D110.316
Eya1eyes absent 1 homolog (Drosophila)0.314
Fzd8frizzled homolog 8 (Drosophila)0.311
Wnt4wingless-related MMTV integration site 40.310
Gdnfglial cell line derived neurotrophic factor0.302
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.292
Shesrc homology 2 domain-containing transforming protein E0.289
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Nek9NIMA (never in mitosis gene a)- related kinase 90.544
Unc5bunc-5 homolog B (C. elegans)0.474
Socs3suppressor of cytokine signaling 30.409
Timp3TIMP metallopeptidase inhibitor 30.406
Myh9myosin, heavy chain 9, non-muscle0.383
Olfml2bolfactomedin-like 2B0.278
Myo1cmyosin IC0.259
Notch2Notch homolog 2 (Drosophila)0.247
Akt2v-akt murine thymoma viral oncogene homolog 20.239
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.215
Tgfbr2transforming growth factor, beta receptor II0.213
Rnf213ring finger protein 2130.196
F13a1coagulation factor XIII, A1 polypeptide0.183
Ednraendothelin receptor type A0.153
Igfbp5insulin-like growth factor binding protein 50.147
Ptmaprothymosin alpha0.147
Irs1insulin receptor substrate 10.141
Glg1golgi apparatus protein 10.141
Acvr1activin A receptor, type I0.136
Prrx1paired related homeobox 10.134
Itpr2inositol 1,4,5-triphosphate receptor, type 20.132
Myf6myogenic factor 60.129
LOC100360403ATP-binding cassette, sub-family C, member 9-like0.129
LOC100362108poly (ADP-ribose) polymerase family, member 100.121
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.120
Stx2syntaxin 20.119
Anpepalanyl (membrane) aminopeptidase0.117
Rxraretinoid X receptor alpha0.116
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.104
Dchs1dachsous 1 (Drosophila)0.102
Sirpasignal-regulatory protein alpha0.101
Pik3r1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.100
Clic4chloride intracellular channel 40.100
Smad1SMAD family member 10.097
Tgfb2transforming growth factor, beta 20.096
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.095
Efnb1ephrin B10.091
Capn5calpain 50.091
Calcrlcalcitonin receptor-like0.090
Col12a1collagen, type XII, alpha 10.090
Myo1dmyosin ID0.088
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.081
Pcnaproliferating cell nuclear antigen0.079
Nfyanuclear transcription factor-Y alpha0.076
Smad3SMAD family member 30.074
Arntaryl hydrocarbon receptor nuclear translocator0.073
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.071
Flt1FMS-related tyrosine kinase 10.071
Scarf2scavenger receptor class F, member 20.071
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.070
Sod3superoxide dismutase 3, extracellular0.067
Hdac7histone deacetylase 70.066
CdonCdon homolog (mouse)0.065
Ubtfupstream binding transcription factor, RNA polymerase I0.064
Nab1Ngfi-A binding protein 10.060
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.060
GperG protein-coupled estrogen receptor 10.059
Lamc1laminin, gamma 10.058
Stat6signal transducer and activator of transcription 60.058
Insrinsulin receptor0.058
Mafv-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)0.056
Smad7SMAD family member 70.055
Gna12guanine nucleotide binding protein (G protein) alpha 120.055
Pik3r3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.053
Ptbp1polypyrimidine tract binding protein 10.053
Ptpn14protein tyrosine phosphatase, non-receptor type 140.052
Srebf1sterol regulatory element binding transcription factor 10.052
Il6stinterleukin 6 signal transducer0.051
Notch1Notch homolog 1, translocation-associated (Drosophila)0.049
Itga6integrin, alpha 60.049
Map3k3mitogen activated protein kinase kinase kinase 30.049
Antxr1anthrax toxin receptor 10.048
Ptprdprotein tyrosine phosphatase, receptor type, D0.047
Slc20a2solute carrier family 20 (phosphate transporter), member 20.047
Sept8septin 80.047
Rab3il1RAB3A interacting protein (rabin3)-like 10.047
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.047
SsbSjogren syndrome antigen B0.046
Abcc1ATP-binding cassette, subfamily C (CFTR/MRP), member 10.046
Stat1signal transducer and activator of transcription 10.045
Wnt5awingless-type MMTV integration site family, member 5A0.045
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.045
Dhx9DEAH (Asp-Glu-Ala-His) box polypeptide 90.045
Nkd1naked cuticle homolog 1 (Drosophila)0.044
Metmet proto-oncogene0.042
Gdf11growth differentiation factor 110.042
Nrasneuroblastoma ras oncogene0.042
Ece1endothelin converting enzyme 10.041
Figfc-fos induced growth factor0.041
Cpxm2carboxypeptidase X (M14 family), member 20.040
Tcfe2atranscription factor E2a0.040
Nr2f2nuclear receptor subfamily 2, group F, member 20.039
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism