The network for 'eosinophil differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

eosinophil differentiation

The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.

NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 11.000
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.994
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.970
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.939
RUNX1runt-related transcription factor 10.770
KLF13Kruppel-like factor 130.701
GATA2GATA binding protein 20.591
GATA1GATA binding protein 1 (globin transcription factor 1)0.505
ZFPM1zinc finger protein, multitype 10.202
KLF1Kruppel-like factor 1 (erythroid)0.164
HAND2heart and neural crest derivatives expressed 20.125
NR5A1nuclear receptor subfamily 5, group A, member 10.119
ANK1ankyrin 1, erythrocytic0.108
LMO2LIM domain only 2 (rhombotin-like 1)0.099
RHAGRh-associated glycoprotein0.085
ZBTB16zinc finger and BTB domain containing 160.074
GP1BAglycoprotein Ib (platelet), alpha polypeptide0.073
MYL4myosin, light chain 4, alkali; atrial, embryonic0.069
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.066
AMHR2anti-Mullerian hormone receptor, type II0.046
BHLHE23basic helix-loop-helix family, member e230.041
DHHdesert hedgehog0.036
LYL1lymphoblastic leukemia derived sequence 10.035
GATA5GATA binding protein 50.028
GATA4GATA binding protein 40.027
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.026
PF4platelet factor 40.025
ALX4ALX homeobox 40.024
KELKell blood group, metallo-endopeptidase0.023
SPIBSpi-B transcription factor (Spi-1/PU.1 related)0.021
HOXB9homeobox B90.020
HBQ1hemoglobin, theta 10.019
TBX1T-box 10.017
SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)0.017
KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 20.016
ICAM4intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)0.016
ALAS2aminolevulinate, delta-, synthase 20.015
PAX5paired box 50.013
NFE2nuclear factor (erythroid-derived 2), 45kDa0.013
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.013
EPXeosinophil peroxidase0.012
WT1Wilms tumor 10.012
SFRP5secreted frizzled-related protein 50.012
MPLmyeloproliferative leukemia virus oncogene0.012
SPTBspectrin, beta, erythrocytic0.012
TFR2transferrin receptor 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tal1T-cell acute lymphocytic leukemia 10.898
Il13interleukin 130.458
Il17ainterleukin 17A0.347
Gfi1bgrowth factor independent 1B0.301
Il2interleukin 20.222
Slc4a1solute carrier family 4 (anion exchanger), member 10.218
Traf3ip2TRAF3 interacting protein 20.211
Il17finterleukin 17F0.149
Trim10tripartite motif-containing 100.077
Eporerythropoietin receptor0.069
Klf1Kruppel-like factor 1 (erythroid)0.051
RhagRhesus blood group-associated A glycoprotein0.046
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.046
Zfpm1zinc finger protein, multitype 10.037
Latlinker for activation of T cells0.032
Foxf1aforkhead box F1a0.031
KelKell blood group0.027
Mybmyeloblastosis oncogene0.026
Elaneelastase, neutrophil expressed0.023
Rag1recombination activating gene 10.022
Mpomyeloperoxidase0.022
Gypaglycophorin A0.020
Gp1baglycoprotein 1b, alpha polypeptide0.020
Ermaperythroblast membrane-associated protein0.020
Hand1heart and neural crest derivatives expressed transcript 10.016
Spna1spectrin alpha 10.016
Il4interleukin 40.016
Hemgnhemogen0.015
Gp9glycoprotein 9 (platelet)0.015
Ltflactotransferrin0.014
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.013
Itga2bintegrin alpha 2b0.013
Hba-xhemoglobin X, alpha-like embryonic chain in Hba complex0.013
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.013
Gp5glycoprotein 5 (platelet)0.012
Robo4roundabout homolog 4 (Drosophila)0.012
Ptpn14protein tyrosine phosphatase, non-receptor type 140.012
Il17rcinterleukin 17 receptor C0.012
Epb4.2erythrocyte protein band 4.20.011
Ngpneutrophilic granule protein0.011
Cox8ccytochrome c oxidase, subunit VIIIc0.011
Tcf15transcription factor 150.011
Slc38a5solute carrier family 38, member 50.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism