The network for 'neutrophil chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neutrophil chemotaxis

The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

NameDescriptionProbabilityFunc Analog Organism
CCR5chemokine (C-C motif) receptor 50.989
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.977
IL8interleukin 80.975
S100A6S100 calcium binding protein A60.967
S100A11S100 calcium binding protein A110.948
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.932
CCL5chemokine (C-C motif) ligand 50.918
CXCL2chemokine (C-X-C motif) ligand 20.911
S100A9S100 calcium binding protein A90.864
CCL2chemokine (C-C motif) ligand 20.835
CCL4chemokine (C-C motif) ligand 40.829
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.806
S100BS100 calcium binding protein B0.793
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.764
S100A4S100 calcium binding protein A40.760
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.758
DPP4dipeptidyl-peptidase 40.712
MDM2Mdm2 p53 binding protein homolog (mouse)0.664
CXCL10chemokine (C-X-C motif) ligand 100.639
IL1Binterleukin 1, beta0.631
NCF2neutrophil cytosolic factor 20.613
ANXA2annexin A20.576
CXCL3chemokine (C-X-C motif) ligand 30.552
FLNAfilamin A, alpha0.537
MPZL2myelin protein zero-like 20.514
S100A8S100 calcium binding protein A80.513
CXCL9chemokine (C-X-C motif) ligand 90.489
TIMP1TIMP metallopeptidase inhibitor 10.466
MPZL3myelin protein zero-like 30.460
CCR1chemokine (C-C motif) receptor 10.448
S100A1S100 calcium binding protein A10.429
GRB2growth factor receptor-bound protein 20.388
IL6interleukin 6 (interferon, beta 2)0.367
CXCR4chemokine (C-X-C motif) receptor 40.365
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.356
SYKspleen tyrosine kinase0.353
ICAM1intercellular adhesion molecule 10.345
LGALS1lectin, galactoside-binding, soluble, 10.344
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.330
PLEKpleckstrin0.326
CCL22chemokine (C-C motif) ligand 220.324
FN1fibronectin 10.323
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.314
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.300
CD63CD63 molecule0.278
SLASrc-like-adaptor0.276
CCL19chemokine (C-C motif) ligand 190.274
IL2RBinterleukin 2 receptor, beta0.274
PLAURplasminogen activator, urokinase receptor0.251
CCL20chemokine (C-C motif) ligand 200.246
MTORmechanistic target of rapamycin (serine/threonine kinase)0.245
NCF1neutrophil cytosolic factor 10.236
VCAM1vascular cell adhesion molecule 10.227
EMP3epithelial membrane protein 30.218
NCF4neutrophil cytosolic factor 4, 40kDa0.212
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.209
S100A14S100 calcium binding protein A140.207
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.203
IFNGinterferon, gamma0.198
CCR7chemokine (C-C motif) receptor 70.188
CCL8chemokine (C-C motif) ligand 80.184
TLR2toll-like receptor 20.183
CXCL11chemokine (C-X-C motif) ligand 110.182
CAPGcapping protein (actin filament), gelsolin-like0.182
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.169
S100A10S100 calcium binding protein A100.167
CXCL13chemokine (C-X-C motif) ligand 130.141
CXCL5chemokine (C-X-C motif) ligand 50.139
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.137
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.134
TNFAIP6tumor necrosis factor, alpha-induced protein 60.133
FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32)0.128
CCL7chemokine (C-C motif) ligand 70.126
ANXA5annexin A50.117
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.109
CD163CD163 molecule0.096
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.095
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.088
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.088
GAS7growth arrest-specific 70.086
IL1R2interleukin 1 receptor, type II0.086
AREGamphiregulin0.085
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.084
TMSB10thymosin beta 100.081
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.080
SOD2superoxide dismutase 2, mitochondrial0.080
C5AR1complement component 5a receptor 10.079
EPS8epidermal growth factor receptor pathway substrate 80.079
MSNmoesin0.077
VAV1vav 1 guanine nucleotide exchange factor0.072
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.072
UBASH3Bubiquitin associated and SH3 domain containing B0.070
SELEselectin E0.068
CALCOCO2calcium binding and coiled-coil domain 20.066
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.066
IL10interleukin 100.065
TYROBPTYRO protein tyrosine kinase binding protein0.065
SH3BP2SH3-domain binding protein 20.064
S100A12S100 calcium binding protein A120.063
S100PS100 calcium binding protein P0.062
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
csf3rcolony stimulating factor 3 receptor (granulocyte)0.340
kdrlkinase insert domain receptor like0.240
cdh1cadherin 1, epithelial0.224
mmp9matrix metalloproteinase 90.222
ptpn6protein tyrosine phosphatase, non-receptor type 60.119
btkBruton agammaglobulinemia tyrosine kinase0.118
nod1nucleotide-binding oligomerization domain containing 10.117
ptprcprotein tyrosine phosphatase, receptor type, C0.105
myd88myeloid differentiation primary response gene (88)0.100
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.098
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.090
mpeg1macrophage expressed 10.079
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.078
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.077
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.076
gmfgglia maturation factor, gamma0.060
jam2ajunctional adhesion molecule 2a0.056
card9caspase recruitment domain family, member 90.054
lta4hleukotriene A4 hydrolase0.049
LOC557072caspase recruitment domain-containing protein 11-like0.045
fbn2bfibrillin 2b0.041
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.037
lrrc6leucine rich repeat containing 60.037
si:ch211-284e13.2si:ch211-284e13.20.037
fli1bfriend leukemia integration 1b0.036
si:dkey-12o15.1si:dkey-12o15.10.036
lrrc33leucine rich repeat containing 330.035
coro1acoronin, actin binding protein, 1A0.034
fras1Fraser syndrome 10.034
cxcr4bchemokine (C-X-C motif), receptor 4b0.031
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.029
postnperiostin, osteoblast specific factor0.027
myhz2myosin, heavy polypeptide 2, fast muscle specific0.027
flncbfilamin C, gamma b (actin binding protein 280)0.026
clic4chloride intracellular channel 40.026
s1pr2sphingosine-1-phosphate receptor 20.024
crhcorticotropin releasing hormone0.023
lyzlysozyme0.023
mychmyelocytomatosis oncogene homolog0.021
im:7146310im:71463100.019
elovl6lELOVL family member 6, elongation of long chain fatty acids like0.019
grap2bGRB2-related adaptor protein 2b0.018
comtacatechol-O-methyltransferase a0.018
smad3aMAD homolog 3a (Drosophila)0.018
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.018
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.018
si:dkeyp-22b2.3si:dkeyp-22b2.30.017
fabp1b.1fatty acid binding protein 1b, tandem duplicate 10.017
f11rF11 receptor0.017
itga2bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)0.017
zgc:101523zgc:1015230.017
LOC553366hypothetical protein LOC5533660.017
il6rinterleukin 6 receptor0.016
metap2methionyl aminopeptidase 20.016
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.016
ambra1autophagy/beclin-1 regulator 10.016
sgpl1sphingosine-1-phosphate lyase 10.016
ikzf1IKAROS family zinc finger 1 (Ikaros)0.016
tyrp1btyrosinase-related protein 1b0.016
nrp2bneuropilin 2b0.016
zgc:110010zgc:1100100.016
tnfatumor necrosis factor a (TNF superfamily, member 2)0.015
esrp2epithelial splicing regulatory protein 20.015
cxcr4achemokine (C-X-C motif) receptor 4a0.015
tnfaip8l2btumor necrosis factor, alpha-induced protein 8, like 2b0.015
pth1aparathyroid hormone 1a0.015
ncf1neutrophil cytosolic factor 10.015
ghrlghrelin/obestatin preprohormone0.014
mpzl2myelin protein zero-like 20.014
meox1mesenchyme homeobox 10.014
ccr9bchemokine (C-C motif) receptor 9b0.014
ntn2netrin 20.014
rhogbras homolog gene family, member Gb0.014
rspo1R-spondin homolog (Xenopus laevis)0.014
mmp13amatrix metalloproteinase 13a0.014
myo9bmyosin IXb0.014
si:dkey-233h2.3si:dkey-233h2.30.013
myf5myogenic factor 50.013
yrkYes-related kinase0.013
zgc:152830zgc:1528300.013
apoa1apolipoprotein A-I0.013
itm2bbintegral membrane protein 2Bb0.013
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.013
spon2aspondin 2a, extracellular matrix protein0.013
tnfaip8l2atumor necrosis factor, alpha-induced protein 8, like 2a0.013
ctssb.2cathepsin S, b.20.013
jam3ajunctional adhesion molecule 3a0.012
mycl1bv-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b0.012
tmprss4atransmembrane protease, serine 4a0.012
rac2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.012
pck2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.012
slc27a2solute carrier family 27 (fatty acid transporter), member 20.012
ccr12.3chemokine (C-C motif) receptor 12.30.012
epcamepithelial cell adhesion molecule0.012
im:7154036im:71540360.011
foxn1forkhead box N10.011
dzip1DAZ interacting protein 10.011
slc24a5solute carrier family 24, member 50.011
myod1myogenic differentiation 10.011
gcm2glial cells missing homolog 2 (Drosophila)0.011
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccr1chemokine (C-C motif) receptor 10.993
Lyz2lysozyme 20.981
Selpselectin, platelet0.971
Ccr2chemokine (C-C motif) receptor 20.965
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.917
Itgb2integrin beta 20.902
Il1binterleukin 1 beta0.890
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.881
Cxcl2chemokine (C-X-C motif) ligand 20.868
Slfn1schlafen 10.820
Cxcr2chemokine (C-X-C motif) receptor 20.819
Ccl2chemokine (C-C motif) ligand 20.818
Ccl4chemokine (C-C motif) ligand 40.737
Clec4dC-type lectin domain family 4, member d0.731
Cd44CD44 antigen0.681
AF251705cDNA sequence AF2517050.669
Fpr1formyl peptide receptor 10.656
Mmp8matrix metallopeptidase 80.646
Ccl3chemokine (C-C motif) ligand 30.573
Ptprcprotein tyrosine phosphatase, receptor type, C0.573
Il1rninterleukin 1 receptor antagonist0.570
Msr1macrophage scavenger receptor 10.558
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.557
Cd40CD40 antigen0.528
Irg1immunoresponsive gene 10.508
Sellselectin, lymphocyte0.501
Seleselectin, endothelial cell0.501
Cxcl1chemokine (C-X-C motif) ligand 10.498
Fcgr1Fc receptor, IgG, high affinity I0.482
Itgaxintegrin alpha X0.473
Myo1fmyosin IF0.430
Clec4nC-type lectin domain family 4, member n0.421
Slpisecretory leukocyte peptidase inhibitor0.415
Il1ainterleukin 1 alpha0.397
C5ar1complement component 5a receptor 10.373
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.360
Il18rapinterleukin 18 receptor accessory protein0.339
Tgfb1transforming growth factor, beta 10.333
Sfpi1SFFV proviral integration 10.324
Ccl7chemokine (C-C motif) ligand 70.313
Ccr7chemokine (C-C motif) receptor 70.307
Slc11a1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.301
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.297
Pdcd1programmed cell death 10.295
Itgalintegrin alpha L0.291
Socs1suppressor of cytokine signaling 10.290
Gpr132G protein-coupled receptor 1320.289
Mmp9matrix metallopeptidase 90.285
Bdkrb1bradykinin receptor, beta 10.283
Klra2killer cell lectin-like receptor, subfamily A, member 20.280
Mmp12matrix metallopeptidase 120.276
Ltblymphotoxin B0.259
Csf1colony stimulating factor 1 (macrophage)0.252
Clec4eC-type lectin domain family 4, member e0.249
Xcr1chemokine (C motif) receptor 10.248
Gzmagranzyme A0.244
Ccr5chemokine (C-C motif) receptor 50.236
Inpp5dinositol polyphosphate-5-phosphatase D0.233
Icam1intercellular adhesion molecule 10.230
Siglecesialic acid binding Ig-like lectin E0.230
Ccl12chemokine (C-C motif) ligand 120.227
Tlr2toll-like receptor 20.221
Slfn4schlafen 40.214
Fpr2formyl peptide receptor 20.210
Ccl8chemokine (C-C motif) ligand 80.210
TyrobpTYRO protein tyrosine kinase binding protein0.208
Gp9glycoprotein 9 (platelet)0.208
Ch25hcholesterol 25-hydroxylase0.204
Il2rbinterleukin 2 receptor, beta chain0.192
Dlg1discs, large homolog 1 (Drosophila)0.190
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.190
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.186
Folr2folate receptor 2 (fetal)0.181
Col4a3collagen, type IV, alpha 30.179
Ngpneutrophilic granule protein0.175
Ncr1natural cytotoxicity triggering receptor 10.173
Nr3c1nuclear receptor subfamily 3, group C, member 10.170
Cd300ldCD300 molecule-like family member d0.168
Has1hyaluronan synthase10.167
Vav1vav 1 oncogene0.165
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.164
Rac1RAS-related C3 botulinum substrate 10.163
Lilrb3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.158
Cx3cr1chemokine (C-X3-C) receptor 10.156
Gm14548predicted gene 145480.154
Lcn2lipocalin 20.154
Cxcl13chemokine (C-X-C motif) ligand 130.152
Lama5laminin, alpha 50.151
Il6interleukin 60.150
Ikzf1IKAROS family zinc finger 10.149
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.148
SrcRous sarcoma oncogene0.148
Tnfaip2tumor necrosis factor, alpha-induced protein 20.148
Batfbasic leucine zipper transcription factor, ATF-like0.147
MefvMediterranean fever0.147
Hckhemopoietic cell kinase0.141
Cd14CD14 antigen0.141
Ctnnb1catenin (cadherin associated protein), beta 10.140
Hmox1heme oxygenase (decycling) 10.137
Il1r1interleukin 1 receptor, type I0.136
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ccl2chemokine (C-C motif) ligand 20.996
Il1binterleukin 1 beta0.981
Cxcl2chemokine (C-X-C motif) ligand 20.965
S100a9S100 calcium binding protein A90.858
Cd14CD14 molecule0.812
S100a8S100 calcium binding protein A80.797
Il6interleukin 60.713
Cxcl10chemokine (C-X-C motif) ligand 100.659
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.496
Ccl3chemokine (C-C motif) ligand 30.460
Ccl4chemokine (C-C motif) ligand 40.437
Timp1TIMP metallopeptidase inhibitor 10.424
Neurl3neuralized homolog 3 (Drosophila)0.408
Il1ainterleukin 1 alpha0.371
Lilrb4leukocyte immunoglobulin-like receptor, subfamily B, member 40.167
Tgm1transglutaminase 1, K polypeptide0.155
Il1r2interleukin 1 receptor, type II0.150
Tnftumor necrosis factor (TNF superfamily, member 2)0.138
Igsf6immunoglobulin superfamily, member 60.133
Ccl20chemokine (C-C motif) ligand 200.133
Nkg7natural killer cell group 7 sequence0.125
Socs3suppressor of cytokine signaling 30.124
Hba-a2hemoglobin alpha, adult chain 20.102
F2rl1coagulation factor II (thrombin) receptor-like 10.094
Il8rbinterleukin 8 receptor, beta0.093
RT1-DaRT1 class II, locus Da0.093
Plekpleckstrin0.086
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.085
Il2rbinterleukin 2 receptor, beta0.085
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.078
Cd37CD37 molecule0.077
Hckhemopoietic cell kinase0.077
RT1-BaRT1 class II, locus Ba0.070
S100a4S100 calcium-binding protein A40.065
Ccl5chemokine (C-C motif) ligand 50.063
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.062
Ptafrplatelet-activating factor receptor0.061
Tspotranslocator protein0.057
Thbdthrombomodulin0.053
S100a11S100 calcium binding protein A11 (calizzarin)0.050
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.048
Ccl7chemokine (C-C motif) ligand 70.048
Il2rginterleukin 2 receptor, gamma0.047
S100a10S100 calcium binding protein A100.046
Gpsm3G-protein signaling modulator 3 (AGS3-like, C. elegans)0.045
Cd44Cd44 molecule0.044
Cxcl3chemokine (C-X-C motif) ligand 30.044
Anxa1annexin A10.043
F13a1coagulation factor XIII, A1 polypeptide0.040
Runx1runt-related transcription factor 10.040
Ccr2chemokine (C-C motif) receptor 20.039
C5ar1complement component 5a receptor 10.037
Slco2b1solute carrier organic anion transporter family, member 2b10.037
Mmp8matrix metallopeptidase 80.033
Cd68Cd68 molecule0.033
Sellselectin L0.033
Emp3epithelial membrane protein 30.030
S100a6S100 calcium binding protein A60.030
Fosl1fos-like antigen 10.029
MefvMediterranean fever0.029
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.025
Cxcl11chemokine (C-X-C motif) ligand 110.025
Ripk3receptor-interacting serine-threonine kinase 30.025
Rab20RAB20, member RAS oncogene family0.025
Ccr5chemokine (C-C motif) receptor 50.024
LOC100363783rCG53773-like0.024
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.023
Gzmkgranzyme K0.023
Reg3gregenerating islet-derived 3 gamma0.022
Icam1intercellular adhesion molecule 10.021
LOC24906RoBo-10.021
Cd53Cd53 molecule0.021
TcrbT-cell receptor beta chain0.021
Il1rninterleukin 1 receptor antagonist0.020
Tmem88transmembrane protein 880.019
Csf1colony stimulating factor 1 (macrophage)0.019
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.019
F2rl2coagulation factor II (thrombin) receptor-like 20.019
Cd86CD86 molecule0.017
Fcn1ficolin (collagen/fibrinogen domain containing) 10.017
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.016
Ubdubiquitin D0.016
Selpselectin P0.016
Anxa2annexin A20.016
Cd8aCD8a molecule0.016
Nraddneurotrophin receptor associated death domain0.016
Fgl2fibrinogen-like 20.015
Gpnmbglycoprotein (transmembrane) nmb0.015
Pde6hphosphodiesterase 6H, cGMP-specific, cone, gamma0.015
Hpgdshematopoietic prostaglandin D synthase0.015
Reg3bregenerating islet-derived 3 beta0.014
Cd83CD83 molecule0.014
Hbbhemoglobin, beta0.014
Ch25hcholesterol 25-hydroxylase0.014
RT1-Db1RT1 class II, locus Db10.014
Tlr7toll-like receptor 70.014
Olr1082olfactory receptor 10820.014
Vcanversican0.013
Olr1500olfactory receptor 15000.013
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism