The network for 'neuron projection development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuron projection development

The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

NameDescriptionProbabilityFunc Analog Organism
FYNFYN oncogene related to SRC, FGR, YES1.000
EGFRepidermal growth factor receptor1.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
QKIquaking homolog, KH domain RNA binding (mouse)0.998
ATXN1ataxin 10.996
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.993
GRB2growth factor receptor-bound protein 20.993
SMURF2SMAD specific E3 ubiquitin protein ligase 20.989
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.987
SMAD2SMAD family member 20.984
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.984
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.983
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.974
FN1fibronectin 10.970
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.969
FLNAfilamin A, alpha0.964
HDAC2histone deacetylase 20.958
ATN1atrophin 10.957
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.956
BCAR1breast cancer anti-estrogen resistance 10.950
RBBP4retinoblastoma binding protein 40.927
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.923
JUNjun proto-oncogene0.922
SYKspleen tyrosine kinase0.908
HDAC1histone deacetylase 10.898
FGFR1fibroblast growth factor receptor 10.892
APPamyloid beta (A4) precursor protein0.888
LCKlymphocyte-specific protein tyrosine kinase0.885
ITSN1intersectin 1 (SH3 domain protein)0.874
CREBBPCREB binding protein0.864
NCOR1nuclear receptor corepressor 10.864
METmet proto-oncogene (hepatocyte growth factor receptor)0.854
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.817
VAV1vav 1 guanine nucleotide exchange factor0.815
ZMYND11zinc finger, MYND-type containing 110.804
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.800
WASLWiskott-Aldrich syndrome-like0.799
MAPK8mitogen-activated protein kinase 80.798
DLG4discs, large homolog 4 (Drosophila)0.772
FOSFBJ murine osteosarcoma viral oncogene homolog0.755
NCAM1neural cell adhesion molecule 10.745
CREB1cAMP responsive element binding protein 10.742
PTK2PTK2 protein tyrosine kinase 20.739
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.733
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.722
EP300E1A binding protein p3000.719
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.718
SMAD3SMAD family member 30.707
MAPTmicrotubule-associated protein tau0.702
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.695
RB1retinoblastoma 10.684
ATF2activating transcription factor 20.680
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.671
PLCG1phospholipase C, gamma 10.668
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.658
ARandrogen receptor0.657
LATlinker for activation of T cells0.651
IQGAP1IQ motif containing GTPase activating protein 10.648
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.644
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.636
SIN3ASIN3 homolog A, transcription regulator (yeast)0.632
BAIAP2BAI1-associated protein 20.628
TAL1T-cell acute lymphocytic leukemia 10.622
ARHGAP1Rho GTPase activating protein 10.618
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.614
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.610
JAG1jagged 10.609
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.606
PTPRCprotein tyrosine phosphatase, receptor type, C0.589
AKT1v-akt murine thymoma viral oncogene homolog 10.585
RUNX1runt-related transcription factor 10.573
ABI1abl-interactor 10.568
MAP3K5mitogen-activated protein kinase kinase kinase 50.566
YAP1Yes-associated protein 10.562
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.558
SOS1son of sevenless homolog 1 (Drosophila)0.555
MPRIPmyosin phosphatase Rho interacting protein0.554
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.546
REREarginine-glutamic acid dipeptide (RE) repeats0.542
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.526
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.525
SMAD4SMAD family member 40.523
STRN3striatin, calmodulin binding protein 30.517
JAK2Janus kinase 20.515
NTNG1netrin G10.512
LAMC1laminin, gamma 1 (formerly LAMB2)0.512
NCK1NCK adaptor protein 10.511
PRKCZprotein kinase C, zeta0.506
RAB1ARAB1A, member RAS oncogene family0.504
STK3serine/threonine kinase 30.504
MAP2K4mitogen-activated protein kinase kinase 40.502
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.493
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.491
PTPN1protein tyrosine phosphatase, non-receptor type 10.490
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.489
MAP4K5mitogen-activated protein kinase kinase kinase kinase 50.483
CTNND1catenin (cadherin-associated protein), delta 10.481
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.479
ARRB1arrestin, beta 10.477
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.974
pha-4Protein PHA-40.970
ceh-20Protein CEH-200.887
ten-1Protein TEN-10.858
hlh-1Protein HLH-10.835
hlh-2Protein HLH-20.823
pry-1Protein PRY-10.810
daf-11Protein DAF-110.798
hbl-1Protein HBL-10.773
ldb-1Protein LDB-10.744
sli-1Protein SLI-10.715
unc-73Protein UNC-730.708
bar-1Protein BAR-10.686
ain-1Protein AIN-10.685
egl-13Protein EGL-130.680
egl-46Protein EGL-460.666
cye-1Protein CYE-10.648
elt-6Protein ELT-60.636
ajm-1Protein AJM-10.623
mab-5Protein MAB-50.612
unc-52Protein UNC-520.601
T28F4.1Protein T28F4.10.597
sma-1Protein SMA-10.564
nhr-67Protein NHR-670.563
zip-7Protein ZIP-70.556
eor-1Protein EOR-10.544
peb-1Protein PEB-10.538
unc-42Protein UNC-420.520
T27A3.1Protein T27A3.10.518
sma-6Protein SMA-60.515
unc-62Protein UNC-620.513
unc-70Protein UNC-700.492
lin-29Protein LIN-290.490
egl-8Protein EGL-80.481
chd-7Protein CHD-70.467
asd-1Protein ASD-10.455
vab-10Protein VAB-100.446
unc-6Protein UNC-60.435
eif-3.IProtein EIF-3.I0.433
lsy-2Protein LSY-20.432
tbc-2Protein TBC-20.431
fkh-2Protein FKH-20.424
skp-1Protein SKP-10.420
cam-1Protein CAM-10.418
C11E4.6Protein C11E4.60.414
egl-5Protein EGL-50.413
sem-5Protein SEM-50.409
pop-1Protein POP-10.401
flt-1Protein FLT-10.398
spdl-1Protein SPDL-10.396
nhr-45Protein NHR-450.395
acs-4Protein ACS-40.373
trim-9Protein TRIM-90.368
unc-53Protein UNC-530.363
sax-3Protein SAX-30.354
teg-4Protein TEG-40.354
let-60Protein LET-600.351
unc-40Protein UNC-400.350
C54E4.2Protein C54E4.20.349
ceh-34Protein CEH-340.346
pbrm-1Protein PBRM-10.345
cdh-3Protein CDH-30.339
vab-3Protein VAB-30.330
let-2Protein LET-20.330
unc-115Protein UNC-1150.327
hid-1Protein HID-10.326
soc-2Protein SOC-20.326
mig-2Protein MIG-20.325
F53F10.2Protein F53F10.20.320
R90.1Protein R90.10.317
cyk-4Protein CYK-40.314
CELE_Y41E3.11Protein Y41E3.110.313
gsp-1Protein GSP-10.313
epi-1Protein EPI-10.307
lin-48Protein LIN-480.307
unc-43Protein UNC-430.307
cash-1Protein CASH-10.306
irx-1Protein IRX-10.301
tlk-1Protein TLK-10.300
K10D6.4Protein K10D6.40.297
gon-4Protein GON-40.295
spc-1Protein SPC-10.294
sax-7Protein SAX-70.293
syg-1Protein SYG-10.293
eps-8Protein EPS-80.292
egl-15Protein EGL-150.289
madf-5Protein MADF-50.284
srgp-1Protein SRGP-10.282
R10E12.2Protein R10E12.20.282
F10G8.9Protein F10G8.90.276
pxf-1Protein PXF-10.275
pal-1Protein PAL-10.272
aap-1Protein AAP-10.268
egl-44Protein EGL-440.264
unc-104Protein UNC-1040.263
cin-4Protein CIN-40.258
ttyh-1Protein TTYH-10.256
mec-4Protein MEC-40.254
tax-4Protein TAX-40.251
ceh-48Protein CEH-480.250
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pitx3paired-like homeodomain transcription factor 30.998
notch1anotch homolog 1a0.997
gli1GLI-Kruppel family member 10.993
fezf2FEZ family zinc finger 20.992
ndr2nodal-related 20.992
gdf6agrowth differentiation factor 6a0.991
lhx2bLIM homeobox 2b0.989
ttnatitin a0.972
ptch2patched 20.968
olig2oligodendrocyte lineage transcription factor 20.953
epha4beph receptor A4b0.950
six3bsine oculis homeobox homolog 3b0.947
fn1fibronectin 10.942
sox2SRY-box containing gene 20.936
rx3retinal homeobox gene 30.926
nrp1aneuropilin 1a0.924
ncam1aneural cell adhesion molecule 1a0.914
dag1dystroglycan 10.908
fgf3fibroblast growth factor 30.906
nxph1neurexophilin 10.903
robo2roundabout homolog 20.896
foxn4forkhead box N40.896
pax6bpaired box gene 6b0.894
ephb4beph receptor B4b0.893
lamc1laminin, gamma 10.886
gli2aGLI-Kruppel family member GLI2a0.886
nr2e1nuclear receptor subfamily 2, group E, member 10.885
flhfloating head0.881
atoh7atonal homolog 70.876
myhz2myosin, heavy polypeptide 2, fast muscle specific0.872
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.870
notch2notch homolog 20.864
cntn2contactin 20.864
wnt10awingless-type MMTV integration site family, member 10a0.862
wnt11rwingless-type MMTV integration site family, member 11, related0.857
shhasonic hedgehog a0.833
alcambactivated leukocyte cell adhesion molecule b0.830
itgavintegrin, alpha V0.824
fstl1bfollistatin-like 1b0.820
otx1aorthodenticle homolog 1a0.805
wnt7bawingless-type MMTV integration site family, member 7Ba0.803
six3asine oculis homeobox homolog 3a0.801
smosmoothened homolog (Drosophila)0.798
neurodneurogenic differentiation0.794
prdm14PR domain containing 140.786
fgfr1afibroblast growth factor receptor 1a0.780
otpborthopedia homolog b0.777
lamb1alaminin, beta 1a0.776
tbx1T-box 10.775
gata2aGATA-binding protein 2a0.770
foxp2forkhead box P20.766
lhx5LIM homeobox 50.760
ephb4aeph receptor B4a0.759
dlx5adistal-less homeobox gene 5a0.757
syn2bsynapsin IIb0.756
crabp2acellular retinoic acid binding protein 2, a0.753
pdlim4PDZ and LIM domain 40.752
pcdh18bprotocadherin 18b0.747
pax8paired box gene 80.746
arxaristaless related homeobox0.745
her9hairy-related 90.738
gro1groucho 10.738
foxd3forkhead box D30.736
dpysl2bdihydropyrimidinase-like 2b0.730
mfn2mitofusin 20.729
wnt3wingless-type MMTV integration site family, member 30.728
fgf10afibroblast growth factor 10a0.726
her4.2hairy-related 4.20.726
cdh23cadherin-like 230.719
fras1Fraser syndrome 10.710
igf1rbinsulin-like growth factor 1b receptor0.708
ascl1aachaete-scute complex-like 1a (Drosophila)0.704
wnt11wingless-type MMTV integration site family, member 110.702
olfm2olfactomedin 20.696
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.694
kal1aKallmann syndrome 1a sequence0.691
col2a1acollagen type II, alpha-1a0.684
phox2apaired-like homeobox 2a0.683
bmp2abone morphogenetic protein 2a0.681
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.677
spry4sprouty (Drosophila) homolog 40.667
otpaorthopedia homolog a0.664
sdcbpsyndecan binding protein (syntenin)0.658
egr2bearly growth response 2b0.657
slit3slit (Drosophila) homolog 30.656
eya1eyes absent homolog 10.654
otx5orthodenticle homolog 50.646
irx4biroquois homeobox protein 4b0.646
pou3f1POU class 3 homeobox 10.644
supt6hsuppressor of Ty 6 homolog0.643
mbpmyelin basic protein0.639
ntlano tail a0.632
stmn2bstathmin-like 2b0.630
gpr98G protein-coupled receptor 980.627
pcdh10aprotocadherin 10a0.625
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.847
Dlg4discs, large homolog 4 (Drosophila)0.803
Robo1roundabout homolog 1 (Drosophila)0.681
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.666
Lin7blin-7 homolog b (C. elegans)0.659
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.638
Nrxn1neurexin 10.571
Sp4Sp4 transcription factor0.570
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.557
Itgb1integrin, beta 10.525
Dlgap1discs, large (Drosophila) homolog-associated protein 10.525
Jak1Janus kinase 10.509
Rap1bRAP1B, member of RAS oncogene family0.504
Nrxn3neurexin 30.501
Rhoaras homolog gene family, member A0.457
Nfibnuclear factor I/B0.452
Grip1glutamate receptor interacting protein 10.449
Sncbsynuclein, beta0.440
Gria2glutamate receptor, ionotropic, AMPA 20.435
Dchs1dachsous 1 (Drosophila)0.430
Dlg3discs, large homolog 3 (Drosophila)0.425
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.422
Pfn1profilin 10.410
Klk1c10l2kallikrein 1-related peptidase c10-like 20.399
Trib1tribbles homolog 1 (Drosophila)0.391
Akt1v-akt murine thymoma viral oncogene homolog 10.389
Ednrbendothelin receptor type B0.383
Rimbp2RIMS binding protein 20.381
Jak2Janus kinase 20.376
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.373
Sv2asynaptic vesicle glycoprotein 2a0.368
Smad4SMAD family member 40.365
Hspb1heat shock protein 10.364
Atf3activating transcription factor 30.359
Grm5glutamate receptor, metabotropic 50.343
Tpm3tropomyosin 3, gamma0.343
Anxa2annexin A20.341
Nfianuclear factor I/A0.339
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.339
Errfi1ERBB receptor feedback inhibitor 10.336
FynFYN oncogene related to SRC, FGR, YES0.333
Calcrlcalcitonin receptor-like0.326
Ptpn12protein tyrosine phosphatase, non-receptor type 120.325
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.322
Nr4a3nuclear receptor subfamily 4, group A, member 30.320
Akap5A kinase (PRKA) anchor protein 50.317
Prrx1paired related homeobox 10.317
Cyth3cytohesin 30.315
Appamyloid beta (A4) precursor protein0.312
Cadm1cell adhesion molecule 10.310
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.309
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.300
Kcnd2potassium voltage-gated channel, Shal-related subfamily, member 20.295
Cugbp2CUG triplet repeat, RNA binding protein 20.295
Bdkrb2bradykinin receptor B20.293
Tmod2tropomodulin 20.286
Mapre1microtubule-associated protein, RP/EB family, member 10.285
Map2microtubule-associated protein 20.283
Gata3GATA binding protein 30.281
Nrg1neuregulin 10.280
Map1bmicrotubule-associated protein 1B0.279
Astn1astrotactin 10.278
Capza2capping protein (actin filament) muscle Z-line, alpha 20.276
Pcdhgc3protocadherin gamma subfamily C, 30.275
Strnstriatin, calmodulin binding protein0.275
Actr3ARP3 actin-related protein 3 homolog (yeast)0.273
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.271
Aqp4aquaporin 40.271
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.268
Pls3plastin 3 (T-isoform)0.268
Galnt1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)0.267
Pde4bphosphodiesterase 4B, cAMP specific0.267
Nrcamneuronal cell adhesion molecule0.266
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.266
Galr3galanin receptor 30.265
Mmp10matrix metallopeptidase 100.264
Vav1vav 1 guanine nucleotide exchange factor0.264
Snap25synaptosomal-associated protein 250.262
Gria4glutamate receptor, ionotrophic, AMPA 40.261
Maptmicrotubule-associated protein tau0.258
Rab6bRAB6B, member RAS oncogene family0.257
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.256
Slc4a3solute carrier family 4 (anion exchanger), member 30.254
Prkcdprotein kinase C, delta0.254
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.253
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.253
Bmp3bone morphogenetic protein 30.252
Lzts1leucine zipper, putative tumor suppressor 10.252
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.252
Pou2f2POU class 2 homeobox 20.252
Cplx1complexin 10.250
Tgfbr2transforming growth factor, beta receptor II0.249
Scn3asodium channel, voltage-gated, type III, alpha0.248
Cd4Cd4 molecule0.246
Trpc4transient receptor potential cation channel, subfamily C, member 40.245
Plp1proteolipid protein 10.241
Emp1epithelial membrane protein 10.240
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism