The network for 'anterior posterior axis specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

anterior posterior axis specification

The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

NameDescriptionProbabilityFunc Analog Organism
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)1.000
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.998
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.994
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.990
JUNjun proto-oncogene0.979
SMAD3SMAD family member 30.969
OCRLoculocerebrorenal syndrome of Lowe0.950
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.948
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.934
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.918
FN1fibronectin 10.902
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.894
PRKCZprotein kinase C, zeta0.888
TP53tumor protein p530.886
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.885
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.880
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.878
ANAPC7anaphase promoting complex subunit 70.873
EIF4A3eukaryotic translation initiation factor 4A30.838
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.834
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.823
CUL2cullin 20.819
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.818
SCHIP1schwannomin interacting protein 10.805
HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)0.787
SMAD2SMAD family member 20.779
NCF2neutrophil cytosolic factor 20.776
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.768
GDAguanine deaminase0.766
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.765
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.732
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.698
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.696
APCadenomatous polyposis coli0.693
MAP2K1mitogen-activated protein kinase kinase 10.683
CDC27cell division cycle 27 homolog (S. cerevisiae)0.673
BMP1bone morphogenetic protein 10.669
ARAFv-raf murine sarcoma 3611 viral oncogene homolog0.664
USP11ubiquitin specific peptidase 110.661
HMGA1high mobility group AT-hook 10.657
NXF1nuclear RNA export factor 10.654
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.650
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.638
LSM3LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.626
PALB2partner and localizer of BRCA20.621
SNRPD1small nuclear ribonucleoprotein D1 polypeptide 16kDa0.621
TACC3transforming, acidic coiled-coil containing protein 30.617
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.592
UPF1UPF1 regulator of nonsense transcripts homolog (yeast)0.585
CARM1coactivator-associated arginine methyltransferase 10.578
C19orf39chromosome 19 open reading frame 390.574
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.566
CBX8chromobox homolog 80.559
PTPN11protein tyrosine phosphatase, non-receptor type 110.558
FBLN1fibulin 10.558
YBX1Y box binding protein 10.556
RAD51L1RAD51-like 1 (S. cerevisiae)0.554
GSK3Bglycogen synthase kinase 3 beta0.550
CLNS1Achloride channel, nucleotide-sensitive, 1A0.536
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.531
SETSET nuclear oncogene0.525
MDC1mediator of DNA-damage checkpoint 10.520
ZFYVE9zinc finger, FYVE domain containing 90.516
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.497
VHLvon Hippel-Lindau tumor suppressor0.479
HSPA8heat shock 70kDa protein 80.472
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.472
WNT3Awingless-type MMTV integration site family, member 3A0.470
PRKCIprotein kinase C, iota0.464
XIAPX-linked inhibitor of apoptosis0.461
HNRNPFheterogeneous nuclear ribonucleoprotein F0.447
SMAD4SMAD family member 40.443
RBL2retinoblastoma-like 2 (p130)0.439
KEAP1kelch-like ECH-associated protein 10.433
SH3RF3SH3 domain containing ring finger 30.432
BRCA2breast cancer 2, early onset0.429
XRCC3X-ray repair complementing defective repair in Chinese hamster cells 30.429
CDC25Bcell division cycle 25 homolog B (S. pombe)0.426
ZFXzinc finger protein, X-linked0.424
LLGL1lethal giant larvae homolog 1 (Drosophila)0.419
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.417
ACTN1actinin, alpha 10.417
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.415
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.415
ANAPC5anaphase promoting complex subunit 50.411
PICALMphosphatidylinositol binding clathrin assembly protein0.399
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.397
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.396
CDC20cell division cycle 20 homolog (S. cerevisiae)0.390
SNAP25synaptosomal-associated protein, 25kDa0.379
AKT1v-akt murine thymoma viral oncogene homolog 10.373
ADAM17ADAM metallopeptidase domain 170.372
CD44CD44 molecule (Indian blood group)0.369
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.369
CUL1cullin 10.366
AXIN1axin 10.363
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
par-5Protein PAR-50.801
nhr-25Protein NHR-250.334
let-60Protein LET-600.326
Y47D3A.29Protein Y47D3A.290.260
snr-4Protein SNR-40.198
arx-7Protein ARX-70.180
mpk-1Protein MPK-10.174
chk-1Protein CHK-10.160
wrm-1Protein WRM-10.112
zyg-9Protein ZYG-90.112
mcm-2Protein MCM-20.089
lin-45Protein LIN-450.087
ztf-22Protein ZTF-220.085
cul-2Protein CUL-20.079
mab-5Protein MAB-50.077
par-2Protein PAR-20.075
pgl-1Protein PGL-10.074
grd-1Protein GRD-10.074
cwn-1Protein CWN-10.071
pry-1Protein PRY-10.064
egl-18Protein EGL-180.063
unc-43Protein UNC-430.062
tra-1Protein TRA-10.060
spc-1Protein SPC-10.060
glh-1Protein GLH-10.059
unc-62Protein UNC-620.054
tap-1Protein TAP-10.053
F13B6.1Protein F13B6.10.049
svh-2Protein SVH-20.047
snr-3Protein SNR-30.047
glh-2Protein GLH-20.047
glp-1Protein GLP-10.045
syd-2Protein SYD-20.044
prg-2Protein PRG-20.042
goa-1Protein GOA-10.042
tbg-1Protein TBG-10.042
elc-1Protein ELC-10.041
C17H11.6Protein C17H11.60.040
rig-6Protein RIG-60.040
hpo-32Protein HPO-320.039
ast-1Protein AST-10.039
cki-1Protein CKI-10.039
mac-1Protein MAC-10.038
chd-7Protein CHD-70.037
ani-1Protein ANI-10.037
hid-1Protein HID-10.036
egl-46Protein EGL-460.036
C45G9.6Protein C45G9.60.035
ina-1Protein INA-10.035
sma-6Protein SMA-60.035
lin-3Protein LIN-30.035
pas-3Protein PAS-30.034
W03F8.4Protein W03F8.40.034
fem-1Protein FEM-10.034
CELE_C01G10.8Protein C01G10.80.034
prg-1Protein PRG-10.034
rskn-1Protein RSKN-10.031
unc-98Protein UNC-980.030
gpb-1Protein GPB-10.029
par-3Protein PAR-30.029
xpo-1Protein XPO-10.028
unc-73Protein UNC-730.028
clec-180Protein CLEC-1800.028
rars-1Protein RARS-10.027
ucr-2.3Protein UCR-2.30.027
ajm-1Protein AJM-10.026
gsk-3Protein GSK-30.026
zyg-11Protein ZYG-110.026
bar-1Protein BAR-10.026
ceh-20Protein CEH-200.026
CELE_E01G4.6Protein E01G4.60.025
klp-15Protein KLP-150.025
cec-9Protein CEC-90.025
hlh-30Protein HLH-300.025
csc-1Protein CSC-10.025
CELE_C38D4.9Protein C38D4.90.024
xpo-2Protein XPO-20.024
CELE_C17H12.13Protein C17H12.130.023
pyc-1Protein PYC-10.023
pqn-89Protein PQN-890.023
plx-2Protein PLX-20.023
C50B8.1Protein C50B8.10.023
par-1Protein PAR-10.023
glh-4Protein GLH-40.023
R12E2.1Protein R12E2.10.023
T04B8.5Protein T04B8.50.023
zer-1Protein ZER-10.023
cdh-3Protein CDH-30.023
thoc-2Protein THOC-20.022
Y43H11AL.1Protein Y43H11AL.10.022
retr-1Protein RETR-10.022
cec-1Protein CEC-10.022
cyn-13Protein CYN-130.022
F11E6.7Protein F11E6.70.021
ain-1Protein AIN-10.020
F36D4.5Protein F36D4.50.020
ugt-50Protein UGT-500.020
msh-6Protein MSH-60.020
lit-1Protein LIT-10.020
ubxn-2Protein UBXN-20.020
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.893
ndr2nodal-related 20.688
lef1lymphocyte enhancer binding factor 10.619
nanos3nanos homolog 30.593
wnt11wingless-type MMTV integration site family, member 110.584
mespamesoderm posterior a0.459
ca15bcarbonic anhydrase XV b0.399
ntlano tail a0.392
six4bsine oculis homeobox homolog 4b0.390
prickle1aprickle-like 1 (Drosophila) a0.320
oepone-eyed pinhead0.302
pcdh8protocadherin 80.295
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.289
rarabretinoic acid receptor, alpha b0.287
cdh2cadherin 2, neuronal0.239
bmp4bone morphogenetic protein 40.234
tbx16T-box gene 160.221
her7hairy and enhancer of split related-70.220
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.206
sox19bSRY-box containing gene 19b0.191
dazldaz-like gene0.181
emx3empty spiracles homeobox 30.179
ccnb1cyclin B10.175
flhfloating head0.166
tll1tolloid-like 10.158
orgoogenesis-related gene0.153
rfx2regulatory factor X, 2 (influences HLA class II expression)0.152
tbx20T-box 200.151
brca2breast cancer 2, early onset0.148
sp5lSp5 transcription factor-like0.143
neo1neogenin 10.142
fezf2FEZ family zinc finger 20.136
tpbgltrophoblast glycoprotein-like0.132
etv2ets variant gene 20.129
foxi1forkhead box I10.127
her3hairy-related 30.126
tbx6T-box gene 60.123
lhx1aLIM homeobox 1a0.122
her1hairy-related 10.120
pou5f1POU domain, class 5, transcription factor 10.109
zic5zic family member 5 (odd-paired homolog, Drosophila)0.108
tbx1T-box 10.107
pglyrp2peptidoglycan recognition protein 20.106
has2hyaluronan synthase 20.102
pkd2polycystic kidney disease 20.101
runx1runt-related transcription factor 10.101
aplnrbapelin receptor b0.100
hoxb1bhomeo box B1b0.099
fzd10frizzled homolog 100.092
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.091
pnxposterior neuron-specific homeobox0.090
otx1borthodenticle homolog 1b0.089
foxb1.1forkhead box B1.10.088
piwil2piwi-like 2 (Drosophila)0.088
acvr1lactivin A receptor, type I like0.085
nkd2naked cuticle homolog 2 and naked 2a0.085
bmp2bbone morphogenetic protein 2b0.084
gyltl1bglycosyltransferase-like 1b0.081
mespbmesoderm posterior b0.081
acvr1bactivin A receptor, type IB0.078
nog1noggin 10.077
prkczprotein kinase C, zeta0.076
restRE1-silencing transcription factor0.071
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.071
alcambactivated leukocyte cell adhesion molecule b0.071
pfn2profilin 20.069
sox2SRY-box containing gene 20.068
eya1eyes absent homolog 10.066
gbx1gastrulation brain homeobox 10.066
rx3retinal homeobox gene 30.064
axin1axin 10.064
wnt8awingless-type MMTV integration site family, member 8a0.063
bmpr1aabone morphogenetic protein receptor, type 1aa0.062
notch3notch homolog 30.062
dag1dystroglycan 10.060
dlg2discs, large (Drosophila) homolog 20.060
irx7iroquois homeobox protein 70.060
e2f5E2F transcription factor 50.058
cdx4caudal type homeo box transcription factor 40.057
hoxa13ahomeo box A13a0.056
shhasonic hedgehog a0.056
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.053
wnt2bbwingless-type MMTV integration site family, member 2Bb0.051
cbfbcore-binding factor, beta subunit0.051
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.049
snx1sorting nexin 10.049
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.048
pea3ETS-domain transcription factor pea30.047
spsb1splA/ryanodine receptor domain and SOCS box containing 10.047
fzd7afrizzled homolog 7a0.046
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
bratbrain tumor0.990
phlpole hole0.980
orboo18 RNA-binding protein0.961
eyaeyes absent0.922
Dcp1Decapping protein 10.916
traltrailer hitch0.910
BicDBicaudal D0.887
magomago nashi0.877
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.865
par-6CG5884 gene product from transcript CG5884-RA0.850
aPKCatypical protein kinase C0.822
EgfrEpidermal growth factor receptor0.818
cicubitus interruptus0.792
fs(1)M3female sterile (1) M30.782
pitaCG3941 gene product from transcript CG3941-RA0.770
Brca2Breast cancer 2, early onset homolog0.716
DlicDynein light intermediate chain0.704
spn-Espindle E0.682
ksrkinase suppressor of ras0.624
Fas2Fasciclin 20.602
sec5CG8843 gene product from transcript CG8843-RA0.571
Src64BSrc oncogene at 64B0.566
argosCG4531 gene product from transcript CG4531-RA0.560
par-1CG8201 gene product from transcript CG8201-RA0.500
RpII140RNA polymerase II 140kD subunit0.490
ovoCG6824 gene product from transcript CG6824-RE0.489
Hrb27CHeterogeneous nuclear ribonucleoprotein at 27C0.448
Ras85DRas oncogene at 85D0.438
spensplit ends0.435
Btk29ABtk family kinase at 29A0.381
Hel25EHelicase at 25E0.364
salmspalt major0.362
spn-Aspindle A0.353
ftzfushi tarazu0.327
Myd88CG2078 gene product from transcript CG2078-RA0.319
Gprk2G protein-coupled receptor kinase 20.297
spn-Bspindle B0.287
DpDP transcription factor0.284
Rac1CG2248 gene product from transcript CG2248-RA0.263
AbiAbelson interacting protein0.262
LanALaminin A0.258
CG4771CG4771 gene product from transcript CG4771-RA0.254
mus301mutagen-sensitive 3010.248
Wnt4Wnt oncogene analog 40.248
spn-FCG12114 gene product from transcript CG12114-RA0.244
tho2CG31671 gene product from transcript CG31671-RA0.242
gbbglass bottom boat0.234
VAChTCG32848 gene product from transcript CG32848-RA0.233
fogfolded gastrulation0.227
Rho1CG8416 gene product from transcript CG8416-RB0.225
CG10260CG10260 gene product from transcript CG10260-RB0.222
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism