The network for 'endodermal mesodermal cell signaling involved in heart induction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endodermal mesodermal cell signaling involved in heart induction

Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.

NameDescriptionProbabilityFunc Analog Organism
SP1Sp1 transcription factor0.998
BMPR1Abone morphogenetic protein receptor, type IA0.997
FOXD3forkhead box D30.995
WWP2WW domain containing E3 ubiquitin protein ligase 20.965
SOX10SRY (sex determining region Y)-box 100.912
SOX2SRY (sex determining region Y)-box 20.885
PAX3paired box 30.869
FSTL1follistatin-like 10.760
HMGA1high mobility group AT-hook 10.702
HCFC1host cell factor C1 (VP16-accessory protein)0.687
ETS2v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)0.185
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.175
MEOX2mesenchyme homeobox 20.135
ESR1estrogen receptor 10.121
POU3F3POU class 3 homeobox 30.062
EP300E1A binding protein p3000.061
SMAD7SMAD family member 70.058
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.057
NOVA2neuro-oncological ventral antigen 20.044
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.044
SOX11SRY (sex determining region Y)-box 110.043
ATF7IPactivating transcription factor 7 interacting protein0.038
POU3F2POU class 3 homeobox 20.033
POU4F1POU class 4 homeobox 10.031
SOX1SRY (sex determining region Y)-box 10.031
SMAD3SMAD family member 30.029
POGZpogo transposable element with ZNF domain0.024
SOX21SRY (sex determining region Y)-box 210.022
DRD4dopamine receptor D40.019
FOXE1forkhead box E1 (thyroid transcription factor 2)0.019
BMPR1Bbone morphogenetic protein receptor, type IB0.019
SIN3ASIN3 homolog A, transcription regulator (yeast)0.019
OTPorthopedia homeobox0.019
POU3F1POU class 3 homeobox 10.019
ADARB1adenosine deaminase, RNA-specific, B10.019
TP73tumor protein p730.018
OLIG2oligodendrocyte lineage transcription factor 20.018
NEUROG3neurogenin 30.018
NR0B1nuclear receptor subfamily 0, group B, member 10.017
NKX2-8NK2 homeobox 80.017
HRKharakiri, BCL2 interacting protein (contains only BH3 domain)0.017
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.017
POU3F4POU class 3 homeobox 40.016
LHX1LIM homeobox 10.015
SETD1ASET domain containing 1A0.015
NKX2-1NK2 homeobox 10.015
ELF1E74-like factor 1 (ets domain transcription factor)0.015
BMP2bone morphogenetic protein 20.014
NHLH2nescient helix loop helix 20.014
ZBTB17zinc finger and BTB domain containing 170.014
ATN1atrophin 10.014
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.013
FGF8fibroblast growth factor 8 (androgen-induced)0.013
GBX2gastrulation brain homeobox 20.013
GSC2goosecoid homeobox 20.013
ESR2estrogen receptor 2 (ER beta)0.012
TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta)0.012
NFYAnuclear transcription factor Y, alpha0.012
NFYCnuclear transcription factor Y, gamma0.012
HOXD12homeobox D120.012
ASCL1achaete-scute complex homolog 1 (Drosophila)0.011
DSPPdentin sialophosphoprotein0.011
CD22CD22 molecule0.011
NPAS1neuronal PAS domain protein 10.011
TLX2T-cell leukemia homeobox 20.011
PAX6paired box 60.011
LHX5LIM homeobox 50.010
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.010
SFRP5secreted frizzled-related protein 50.010
FOXA2forkhead box A20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism