The network for 'cilium organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cilium organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.

NameDescriptionProbabilityFunc Analog Organism
APPL1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.946
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.905
BBS4Bardet-Biedl syndrome 40.860
DYNLT3dynein, light chain, Tctex-type 30.849
CENPJcentromere protein J0.800
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.778
DAAM1dishevelled associated activator of morphogenesis 10.771
C19orf50chromosome 19 open reading frame 500.706
TSC22D4TSC22 domain family, member 40.702
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.586
ATP6V1AATPase, H+ transporting, lysosomal 70kDa, V1 subunit A0.581
TUBGCP4tubulin, gamma complex associated protein 40.575
LDOC1leucine zipper, down-regulated in cancer 10.550
PSEN1presenilin 10.535
FGF1fibroblast growth factor 1 (acidic)0.491
ARL6ADP-ribosylation factor-like 60.489
SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)0.431
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.425
BBS7Bardet-Biedl syndrome 70.422
EXOC7exocyst complex component 70.421
ATRXalpha thalassemia/mental retardation syndrome X-linked0.397
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.334
NUDT18nudix (nucleoside diphosphate linked moiety X)-type motif 180.290
BBS2Bardet-Biedl syndrome 20.289
CCDC92coiled-coil domain containing 920.287
TTC30Btetratricopeptide repeat domain 30B0.281
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.275
SIRT2sirtuin 20.274
TFDP2transcription factor Dp-2 (E2F dimerization partner 2)0.269
FGF10fibroblast growth factor 100.268
RAB5ARAB5A, member RAS oncogene family0.265
RBL1retinoblastoma-like 1 (p107)0.247
SASS6spindle assembly 6 homolog (C. elegans)0.241
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.233
CYFIP2cytoplasmic FMR1 interacting protein 20.212
RAB6ARAB6A, member RAS oncogene family0.209
NEK1NIMA (never in mitosis gene a)-related kinase 10.203
FLNBfilamin B, beta0.203
OCRLoculocerebrorenal syndrome of Lowe0.198
SNX9sorting nexin 90.196
ITSN1intersectin 1 (SH3 domain protein)0.192
PCM1pericentriolar material 10.186
GABARAPL1GABA(A) receptor-associated protein like 10.186
ATP6V1B2ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B20.184
LIN9lin-9 homolog (C. elegans)0.181
IFT88intraflagellar transport 88 homolog (Chlamydomonas)0.181
RABGAP1RAB GTPase activating protein 10.180
AP2B1adaptor-related protein complex 2, beta 1 subunit0.180
PSEN2presenilin 2 (Alzheimer disease 4)0.177
LNX1ligand of numb-protein X 10.170
RAB8ARAB8A, member RAS oncogene family0.169
RAB3IPRAB3A interacting protein (rabin3)0.154
LAMTOR3late endosomal/lysosomal adaptor, MAPK and MTOR activator 30.149
RAB10RAB10, member RAS oncogene family0.146
ARL8BADP-ribosylation factor-like 8B0.146
C3orf34chromosome 3 open reading frame 340.142
TTBK2tau tubulin kinase 20.139
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.138
RAB1ARAB1A, member RAS oncogene family0.132
CDT1chromatin licensing and DNA replication factor 10.130
SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)0.129
SSX2IPsynovial sarcoma, X breakpoint 2 interacting protein0.128
DNM2dynamin 20.125
E2F1E2F transcription factor 10.122
KIF3Akinesin family member 3A0.118
WASLWiskott-Aldrich syndrome-like0.118
FASLGFas ligand (TNF superfamily, member 6)0.115
BBS9Bardet-Biedl syndrome 90.115
DZIP3DAZ interacting protein 3, zinc finger0.114
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.112
RABIFRAB interacting factor0.110
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E10.108
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.105
LRRK2leucine-rich repeat kinase 20.105
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.103
TMOD3tropomodulin 3 (ubiquitous)0.103
GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 30.101
RABGAP1LRAB GTPase activating protein 1-like0.101
CALCOCO2calcium binding and coiled-coil domain 20.098
EFCAB7EF-hand calcium binding domain 70.093
CEP290centrosomal protein 290kDa0.091
ALDOBaldolase B, fructose-bisphosphate0.090
ATP6V0CATPase, H+ transporting, lysosomal 16kDa, V0 subunit c0.090
EXOC5exocyst complex component 50.088
CLUAP1clusterin associated protein 10.086
RAB3IL1RAB3A interacting protein (rabin3)-like 10.085
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.085
PRKAR1Aprotein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)0.084
DVL3dishevelled, dsh homolog 3 (Drosophila)0.080
STILSCL/TAL1 interrupting locus0.079
PACSIN2protein kinase C and casein kinase substrate in neurons 20.079
CDK5RAP2CDK5 regulatory subunit associated protein 20.078
ACTR10actin-related protein 10 homolog (S. cerevisiae)0.078
EFHC1EF-hand domain (C-terminal) containing 10.077
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.077
TTC8tetratricopeptide repeat domain 80.076
TJP1tight junction protein 1 (zona occludens 1)0.075
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
osm-5Protein OSM-51.000
osm-6Protein OSM-61.000
che-13Protein CHE-131.000
osm-3Protein OSM-30.999
nphp-4Protein NPHP-40.996
che-11Protein CHE-110.996
che-2Protein CHE-20.995
osm-1Protein OSM-10.975
che-3Protein CHE-30.966
nphp-1Protein NPHP-10.944
daf-10Protein DAF-100.919
osm-12Protein OSM-120.826
bbs-8Protein BBS-80.722
egl-46Protein EGL-460.678
jbts-14Protein JBTS-140.655
arl-13Protein ARL-130.523
bbs-5Protein BBS-50.477
vab-3Protein VAB-30.409
mksr-1Protein MKSR-10.372
bbs-2Protein BBS-20.317
elt-6Protein ELT-60.293
mksr-2Protein MKSR-20.256
bbs-1Protein BBS-10.254
arl-3Protein ARL-30.237
lgc-20Protein LGC-200.165
unc-68Protein UNC-680.154
egl-18Protein EGL-180.141
arl-6Protein ARL-60.140
lrp-2Protein LRP-20.123
CELE_R11H6.2Protein R11H6.20.111
fbxa-137Protein FBXA-1370.109
dyb-1Protein DYB-10.105
Y82E9BR.13Protein Y82E9BR.130.089
CELE_Y39G8B.2Protein Y39G8B.20.088
CELE_Y42A5A.4Protein Y42A5A.40.088
C02B10.5Protein C02B10.50.086
unc-30Protein UNC-300.084
zig-8Protein ZIG-80.078
rhgf-2Protein RHGF-20.074
arrd-19Protein ARRD-190.073
cnd-1Protein CND-10.073
klp-20Protein KLP-200.070
ptr-5Protein PTR-50.068
mks-5Protein MKS-50.066
M151.7Protein M151.70.065
CELE_F08D12.1Protein F08D12.10.064
igcm-2Protein IGCM-20.063
Y55D5A.1Protein Y55D5A.10.061
bbs-9Protein BBS-90.061
CELE_C14A11.5Protein C14A11.50.061
hlh-10Protein HLH-100.060
CELE_T26A8.2Protein T26A8.20.060
klp-11Protein KLP-110.059
zfp-3Protein ZFP-30.058
F52C9.5Protein F52C9.50.057
CELE_F21H7.10Protein F21H7.100.057
del-3Protein DEL-30.052
lin-29Protein LIN-290.052
rab-28Protein RAB-280.052
magu-3Protein MAGU-30.051
T03G11.3Protein T03G11.30.051
sel-11Protein SEL-110.050
nhr-67Protein NHR-670.050
ncs-2Protein NCS-20.049
T24C4.5Protein T24C4.50.048
tctn-1Protein TCTN-10.048
cyn-13Protein CYN-130.046
dyf-13Protein DYF-130.045
lin-12Protein LIN-120.043
tax-4Protein TAX-40.043
unc-53Protein UNC-530.042
pde-5Protein PDE-50.042
CELE_F53C3.3Protein F53C3.30.041
hnd-1Protein HND-10.041
ZK1010.8Protein ZK1010.80.041
dyf-17Protein DYF-170.040
egl-13Protein EGL-130.040
F48F7.3Protein F48F7.30.040
pqn-82Protein PQN-820.040
W02C12.1Protein W02C12.10.039
aex-3Protein AEX-30.039
secs-1Protein SECS-10.038
ula-1Protein ULA-10.038
orc-1Protein ORC-10.038
cwp-4Protein CWP-40.037
ZK430.5Protein ZK430.50.037
mef-2Protein MEF-20.036
mec-6Protein MEC-60.036
rab-6.1Protein RAB-6.10.036
F54E4.3Protein F54E4.30.036
szy-20Protein SZY-200.036
daf-19Protein DAF-190.035
C13C4.5Protein C13C4.50.035
pqn-42Protein PQN-420.034
let-381Protein LET-3810.033
tba-6Protein TBA-60.033
unc-104Protein UNC-1040.033
egl-2Protein EGL-20.033
CELE_Y69H2.7Protein Y69H2.70.032
F39H12.2Protein F39H12.20.031
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ift88intraflagellar transport 88 homolog1.000
lrrc6leucine rich repeat containing 61.000
kif17kinesin family member 171.000
arl13bADP-ribosylation factor-like 13b0.999
ift57intraflagellar transport protein 570.996
ift172intraflagellar transport 1720.991
pkd2polycystic kidney disease 20.989
ccdc40coiled-coil domain containing 400.988
cc2d2acoiled-coil and C2 domain containing 2A0.984
ift52intraflagellar transport protein 520.981
ccdc151coiled-coil domain containing 1510.972
ift80intraflagellar transport 80 homolog (Chlamydomonas)0.932
gli2aGLI-Kruppel family member GLI2a0.906
cluap1clusterin associated protein 10.899
lrrc50leucine rich repeat containing 500.890
ttc21btetratricopeptide repeat domain 21B0.878
notch1anotch homolog 1a0.872
dzip1DAZ interacting protein 10.828
crb2acrumbs homolog 2a0.792
foxj1aforkhead box J1a0.730
traf3ip1TNF receptor-associated factor 3 interacting protein 10.710
rfx2regulatory factor X, 2 (influences HLA class II expression)0.690
epb41l5erythrocyte membrane protein band 4.1 like 50.671
synj1synaptojanin 10.656
aldh1a2aldehyde dehydrogenase 1 family, member A20.654
ift81intraflagellar transport 81 homolog0.556
wdr16WD repeat domain 160.553
LOC563527brain-specific angiogenesis inhibitor 1-like0.544
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.537
ttc26tetratricopeptide repeat domain 260.508
ttll3tubulin tyrosine ligase-like family, member 30.505
ttll6tubulin tyrosine ligase-like family, member 60.500
bbs7Bardet-Biedl syndrome 70.491
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.476
foxj1bforkhead box J1b0.474
mibmind bomb0.453
jag2jagged 20.451
eya1eyes absent homolog 10.438
cdoncell adhesion molecule-related/down-regulated by oncogenes0.434
actc1aactin, alpha, cardiac muscle 1a0.415
dync1h1dynein, cytoplasmic 1, heavy chain 10.411
wnt11wingless-type MMTV integration site family, member 110.401
ofd1oral-facial-digital syndrome 10.398
flhfloating head0.373
grhl2bgrainyhead-like 2b (Drosophila)0.360
hnf1baHNF1 homeobox Ba0.344
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.343
pak1p21/Cdc42/Rac1-activated kinase 10.334
bbs2Bardet-Biedl syndrome 20.333
dync2i1dynein, cytoplasmic 2, intermediate chain 10.311
tsga14testis specific, 140.306
mks1meckel syndrome, type 10.299
e2f5E2F transcription factor 50.299
rtn4rl2breticulon 4 receptor-like 2b0.295
morn3MORN repeat containing 30.287
ift46intraflagellar transport protein 460.273
gli3GLI-Kruppel family member GLI30.267
coblcordon-bleu homolog (mouse)0.259
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.237
lamb1alaminin, beta 1a0.232
fzd8afrizzled homolog 8a0.228
fzd7afrizzled homolog 7a0.226
makmale germ cell-associated kinase0.225
LOC100333015cytoplasmic dynein 2 heavy chain 1-like0.218
wtipWilms tumor 1 interacting protein0.214
crxcone-rod homeobox0.206
ntlano tail a0.206
cacna1dacalcium channel, voltage-dependent, L type, alpha 1D subunit, a0.197
kif3bkinesin family member 3B0.194
micall2amical-like 2a0.193
ccm2cerebral cavernous malformation 20.185
lsrlipolysis stimulated lipoprotein receptor0.185
crb3acrumbs homolog 3a0.184
cbx2chromobox homolog 2 (Drosophila Pc class)0.182
efhc1EF-hand domain (C-terminal) containing 10.178
crb1crumbs homolog 1 (Drosophila)0.172
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.162
crb2bcrumbs homolog 2b0.161
sarsseryl-tRNA synthetase0.160
otx2orthodenticle homolog 20.159
scn1bbsodium channel, voltage-gated, type I, beta b0.157
guca1cguanylate cyclase activator 1C0.154
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.153
foxd3forkhead box D30.150
dctn1adynactin 1a0.150
slc45a2solute carrier family 45, member 20.149
nr2f5nuclear receptor subfamily 2, group F, member 50.149
fzd10frizzled homolog 100.148
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.147
celsr2cadherin, EGF LAG seven-pass G-type receptor 2 and cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)0.144
atp6v1g1ATPase, H+ transporting, V1 subunit G isoform 10.143
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ana1anastral spindle 10.999
tilBtouch insensitive larva B0.976
Cep135CG17081 gene product from transcript CG17081-RB0.886
SAKSak kinase0.851
CG32779CG32779 gene product from transcript CG32779-RA0.701
Sas-4CG10061 gene product from transcript CG10061-RA0.665
Klp64DKinesin-like protein at 64D0.613
Klp68DKinesin-like protein at 68D0.513
numbCG3779 gene product from transcript CG3779-RB0.497
CG3875CG3875 gene product from transcript CG3875-RA0.463
rempAreduced mechanoreceptor potential A0.414
ana2anastral spindle 20.379
nompCno mechanoreceptor potential C0.371
TTLL3BTubulin tyrosine ligase-like 3B0.334
CkIIalpha-i3CKII-alpha subunit interactor-30.327
nompAno mechanoreceptor potential A0.321
lkb1CG9374 gene product from transcript CG9374-RJ0.287
CG1625CG1625 gene product from transcript CG1625-RB0.286
Tak1TGF-beta activated kinase 10.286
LanB1CG7123 gene product from transcript CG7123-RA0.243
LanB2Laminin B20.204
Upf2CG2253 gene product from transcript CG2253-RA0.196
Cp110CG14617 gene product from transcript CG14617-RB0.168
CG17666CG17666 gene product from transcript CG17666-RA0.162
nmdno mitochondrial derivative0.151
kl-3male fertility factor kl30.150
ana3anastral spindle 30.135
CG31473CG31473 gene product from transcript CG31473-RA0.125
CG42247CG42247 gene product from transcript CG42247-RC0.117
CG34168CG34168 gene product from transcript CG34168-RA0.113
Eps-15Epidermal growth factor receptor pathway substrate clone 150.111
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.108
CG15657CG15657 gene product from transcript CG15657-RA0.107
CAPCG18408 gene product from transcript CG18408-RI0.103
cicubitus interruptus0.103
CG3788CG3788 gene product from transcript CG3788-RB0.088
nompBno mechanoreceptor potential B0.087
CG9492CG9492 gene product from transcript CG9492-RA0.086
gekgenghis khan0.085
HGTXCG13475 gene product from transcript CG13475-RB0.084
CG4552CG4552 gene product from transcript CG4552-RA0.080
CG32436CG32436 gene product from transcript CG32436-RA0.079
RhoGAP100FCG1976 gene product from transcript CG1976-RB0.076
CG14921CG14921 gene product from transcript CG14921-RA0.071
CG8214CG8214 gene product from transcript CG8214-RA0.071
CG6499CG6499 gene product from transcript CG6499-RB0.070
galectinCG11372 gene product from transcript CG11372-RA0.068
Prosalpha6TProteasome alpha6T subunit0.068
Cyt-c-dCytochrome c distal0.066
CycACyclin A0.066
qkr58E-3quaking related 58E-30.065
cpbcapping protein beta0.065
CG12184CG12184 gene product from transcript CG12184-RA0.064
CG12027CG12027 gene product from transcript CG12027-RA0.062
CG31961CG31961 gene product from transcript CG31961-RA0.060
CG7742CG7742 gene product from transcript CG7742-RA0.060
CG14840CG14840 gene product from transcript CG14840-RA0.060
Pp1-87BProtein phosphatase 1 at 87B0.060
CG8478CG8478 gene product from transcript CG8478-RD0.059
Mst84DaMale-specific RNA 84Da0.059
CG3563CG3563 gene product from transcript CG3563-RA0.058
CG5280CG5280 gene product from transcript CG5280-RA0.055
endoBendophilin B0.055
osm-1CG13809 gene product from transcript CG13809-RA0.055
Oseg1CG7161 gene product from transcript CG7161-RA0.053
slp2sloppy paired 20.052
Ir75aIonotropic receptor 75a0.051
nmdyn-D7CG8362 gene product from transcript CG8362-RA0.051
CG8155CG8155 gene product from transcript CG8155-RA0.051
Cip4CG15015 gene product from transcript CG15015-RA0.051
Klp59CCG3219 gene product from transcript CG3219-RA0.050
CG34353CG34353 gene product from transcript CG34353-RA0.050
LrrkLeucine-rich repeat kinase0.049
CG31169CG31169 gene product from transcript CG31169-RB0.049
Orc5Origin recognition complex subunit 50.048
Ir76bIonotropic receptor 76b0.048
msd5mitotic spindle density 50.047
sut3sugar transporter 30.047
CG14535CG14535 gene product from transcript CG14535-RA0.046
SlbpStem-loop binding protein0.046
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Lztfl1leucine zipper transcription factor-like 10.022
Dpcddeleted in primary ciliary dyskinesia0.017
Nme7non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)0.017
LOC691849hypothetical protein LOC6918490.017
Tmem107transmembrane protein 1070.015
Bbs5Bardet-Biedl syndrome 50.015
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.015
Tusc3tumor suppressor candidate 30.015
Ift74intraflagellar transport 74 homolog (Chlamydomonas)0.014
Tctex1d2Tctex1 domain containing 20.014
Ehfets homologous factor0.013
Ift57intraflagellar transport 57 homolog (Chlamydomonas)0.013
Arhgap23Rho GTPase activating protein 230.012
Cdc42cell division cycle 42 (GTP binding protein)0.012
Tekt1tektin 10.011
Dnal4dynein, axonemal, light chain 40.011
Sppl2asignal peptide peptidase-like 2A0.011
Zfp637zinc finger protein 6370.010
Tmem17transmembrane protein 170.010
Caprin1cell cycle associated protein 10.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism