The network for 'metaphase anaphase transition of cell cycle' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metaphase anaphase transition of cell cycle

The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.

NameDescriptionProbabilityFunc Analog Organism
CDC20cell division cycle 20 homolog (S. cerevisiae)1.000
CDC27cell division cycle 27 homolog (S. cerevisiae)1.000
ANAPC4anaphase promoting complex subunit 40.998
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.998
CDK2cyclin-dependent kinase 20.997
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.989
CCNA2cyclin A20.978
ANAPC5anaphase promoting complex subunit 50.978
CCNB1cyclin B10.965
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.952
CDC23cell division cycle 23 homolog (S. cerevisiae)0.938
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.894
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.876
ANAPC7anaphase promoting complex subunit 70.836
SMC6structural maintenance of chromosomes 60.808
ANAPC11anaphase promoting complex subunit 110.760
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.744
CCT8chaperonin containing TCP1, subunit 8 (theta)0.686
SKP2S-phase kinase-associated protein 2 (p45)0.671
ORC1origin recognition complex, subunit 10.592
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.566
CBX5chromobox homolog 50.563
SMC3structural maintenance of chromosomes 30.487
CDC26cell division cycle 26 homolog (S. cerevisiae)0.487
AURKBaurora kinase B0.477
PLK1polo-like kinase 10.438
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.431
RB1retinoblastoma 10.424
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.377
CDKN3cyclin-dependent kinase inhibitor 30.349
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.314
CUL1cullin 10.305
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.305
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.300
TCP1t-complex 10.293
STAG1stromal antigen 10.288
SKP1S-phase kinase-associated protein 10.269
CKS1BCDC28 protein kinase regulatory subunit 1B0.229
CDC16cell division cycle 16 homolog (S. cerevisiae)0.220
IGF1Rinsulin-like growth factor 1 receptor0.212
CCNE1cyclin E10.211
VHLvon Hippel-Lindau tumor suppressor0.196
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.179
SHC1SHC (Src homology 2 domain containing) transforming protein 10.171
CDT1chromatin licensing and DNA replication factor 10.171
CD44CD44 molecule (Indian blood group)0.169
WAPALwings apart-like homolog (Drosophila)0.166
CHAF1Achromatin assembly factor 1, subunit A (p150)0.163
TERF1telomeric repeat binding factor (NIMA-interacting) 10.154
ANAPC1anaphase promoting complex subunit 10.144
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.135
PTTG1pituitary tumor-transforming 10.133
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.127
ANAPC10anaphase promoting complex subunit 100.126
CUL2cullin 20.116
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.116
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.116
SKA1spindle and kinetochore associated complex subunit 10.115
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.110
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.106
CUL5cullin 50.105
INCENPinner centromere protein antigens 135/155kDa0.098
HERC2hect domain and RLD 20.097
CCNB2cyclin B20.093
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.092
RAD21RAD21 homolog (S. pombe)0.091
UBE2Cubiquitin-conjugating enzyme E2C0.089
PTK2BPTK2B protein tyrosine kinase 2 beta0.088
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.087
EZRezrin0.085
TCEB2transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)0.082
PPP2R5Aprotein phosphatase 2, regulatory subunit B', alpha0.080
CCT4chaperonin containing TCP1, subunit 4 (delta)0.080
TBC1D10ATBC1 domain family, member 10A0.077
SKA3spindle and kinetochore associated complex subunit 30.075
SMAD2SMAD family member 20.072
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.072
PRNPprion protein0.071
NEK9NIMA (never in mitosis gene a)- related kinase 90.071
COMMD1copper metabolism (Murr1) domain containing 10.070
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.069
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.069
FBXO5F-box protein 50.068
CENPEcentromere protein E, 312kDa0.064
PARP3poly (ADP-ribose) polymerase family, member 30.063
TINF2TERF1 (TRF1)-interacting nuclear factor 20.062
UHRF1ubiquitin-like with PHD and ring finger domains 10.059
NSMCE4Anon-SMC element 4 homolog A (S. cerevisiae)0.059
CLSPNclaspin0.058
SIRT2sirtuin 20.057
BRCA2breast cancer 2, early onset0.057
CCND3cyclin D30.056
BTRCbeta-transducin repeat containing0.056
SGOL1shugoshin-like 1 (S. pombe)0.054
CASC5cancer susceptibility candidate 50.053
AXIN2axin 20.052
E2F1E2F transcription factor 10.051
UBE2Subiquitin-conjugating enzyme E2S0.050
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.049
CREBBPCREB binding protein0.047
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rnr-1Protein RNR-10.396
gpr-2Protein GPR-20.166
CELE_C24H12.5Protein C24H12.50.128
cul-2Protein CUL-20.128
hcp-1Protein HCP-10.121
gpr-1Protein GPR-10.099
math-33Protein MATH-330.093
rod-1Protein ROD-10.082
hcp-2Protein HCP-20.081
ZK507.6Protein ZK507.60.071
rsa-1Protein RSA-10.071
imb-2Protein IMB-20.070
spdl-1Protein SPDL-10.064
cyk-4Protein CYK-40.064
panl-2Protein PANL-20.060
air-2Protein AIR-20.058
bub-1Protein BUB-10.056
bmk-1Protein BMK-10.051
his-42Protein HIS-420.050
him-10Protein HIM-100.042
emb-27Protein EMB-270.035
Y47D3A.29Protein Y47D3A.290.033
uaf-1Protein UAF-10.031
knl-1Protein KNL-10.030
pcn-1Protein PCN-10.029
elc-1Protein ELC-10.029
tra-1Protein TRA-10.027
mcm-7Protein MCM-70.027
T08A11.2Protein T08A11.20.027
hpo-10Protein HPO-100.026
lmn-1Protein LMN-10.026
dsh-2Protein DSH-20.026
ZC434.8Protein ZC434.80.026
ZK930.1Protein ZK930.10.025
cul-1Protein CUL-10.025
R06F6.8Protein R06F6.80.024
prp-21Protein PRP-210.024
mat-3Protein MAT-30.024
flh-1Protein FLH-10.024
F33H2.5Protein F33H2.50.024
mcm-3Protein MCM-30.023
mep-1Protein MEP-10.023
klp-19Protein KLP-190.023
mcm-5Protein MCM-50.023
brd-1Protein BRD-10.023
npp-11Protein NPP-110.022
pod-1Protein POD-10.021
rfl-1Protein RFL-10.021
taf-5Protein TAF-50.021
sas-5Protein SAS-50.021
CELE_K08F4.1Protein K08F4.10.021
lst-3Protein LST-30.021
zyg-9Protein ZYG-90.021
H21P03.2Protein H21P03.20.021
csc-1Protein CSC-10.021
C49H3.9Protein C49H3.90.020
toe-2Protein TOE-20.020
gck-2Protein GCK-20.020
R05D3.2Protein R05D3.20.020
C01H6.9Protein C01H6.90.020
F36D4.5Protein F36D4.50.019
lst-1Protein LST-10.019
hgrs-1Protein HGRS-10.019
clp-2Protein CLP-20.019
prp-3Protein PRP-30.019
ddx-19Protein DDX-190.019
rfc-2Protein RFC-20.018
ebp-2Protein EBP-20.018
zen-4Protein ZEN-40.018
CELE_Y111B2A.10Protein Y111B2A.100.018
K07C5.3Protein K07C5.30.017
T28D9.4Protein T28D9.40.017
smc-5Protein SMC-50.017
ung-1Protein UNG-10.017
Y48G1C.7Protein Y48G1C.70.017
hpo-9Protein HPO-90.017
csn-1Protein CSN-10.016
npp-21Protein NPP-210.016
dcr-1Protein DCR-10.016
bath-42Protein BATH-420.016
cyb-1Protein CYB-10.016
gyg-2Protein GYG-20.015
T09B4.1Protein T09B4.10.015
pch-2Protein PCH-20.015
air-1Protein AIR-10.015
B0491.1Protein B0491.10.014
paqr-2Protein PAQR-20.014
gck-1Protein GCK-10.014
swsn-6Protein SWSN-60.014
trcs-1Protein TRCS-10.014
rpa-2Protein RPA-20.014
smg-8Protein SMG-80.013
brc-1Protein BRC-10.013
rsp-7Protein RSP-70.013
nhr-6Protein NHR-60.013
puf-7Protein PUF-70.013
CELE_W02D7.6Protein W02D7.60.013
B0205.9Protein B0205.90.013
T28C6.7Protein T28C6.70.013
pry-1Protein PRY-10.013
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
hpohippo0.659
Mcm10Sensitized chromosome inheritance modifier 190.555
BubR1Bub1-related kinase0.520
gwlgreatwall0.495
tefutelomere fusion0.385
bratbrain tumor0.375
CycBCyclin B0.374
ncdnon-claret disjunctional0.351
IswiImitation SWI0.332
stgstring0.326
aspabnormal spindle0.326
cmetCENP-meta0.323
CycACyclin A0.310
dupdouble parked0.264
SMC2CG10212 gene product from transcript CG10212-RA0.264
idaimaginal discs arrested0.245
pitaCG3941 gene product from transcript CG3941-RA0.230
SseSeparase0.226
poloCG12306 gene product from transcript CG12306-RA0.219
marsCG17064 gene product from transcript CG17064-RB0.208
Kmn1kinetochore Mis12-Ndc80 network component 10.188
Klp61FKinesin-like protein at 61F0.181
Rpd3CG7471 gene product from transcript CG7471-RA0.175
borrborealin-related0.155
fzyfizzy0.141
Nuf2CG8902 gene product from transcript CG8902-RA0.141
cdc2CG5363 gene product from transcript CG5363-RA0.134
kukkugelkern0.133
DrefDNA replication-related element factor0.130
CycB3Cyclin B30.129
cavcaravaggio0.126
cdc16CG6759 gene product from transcript CG6759-RA0.122
pimpimples0.117
cidcentromere identifier0.110
Cdc37CG12019 gene product from transcript CG12019-RA0.102
Orc2Origin recognition complex subunit 20.099
nbsCG6754 gene product from transcript CG6754-RC0.089
alphaTub67Calpha-Tubulin at 67C0.086
Mcm2Minichromosome maintenance 20.077
Aos1CG12276 gene product from transcript CG12276-RA0.076
flflfalafel0.076
Spc105RSpc105-related0.074
Klp3AKinesin-like protein at 3A0.072
CG9772CG9772 gene product from transcript CG9772-RB0.070
droshaCG8730 gene product from transcript CG8730-RA0.070
DNApol-alpha60DNA polymerase alpha 60kD0.064
thrthree rows0.064
shtdshattered0.063
scrascraps0.060
nodno distributive disjunction0.059
rodrough deal0.057
Ras85DRas oncogene at 85D0.056
piepineapple eye0.053
Cenp-CCG31258 gene product from transcript CG31258-RA0.050
IncenpInner centromere protein0.050
Ndc80CG9938 gene product from transcript CG9938-RA0.049
cortcortex0.048
Bj1Bj1 protein0.048
Cks30ACyclin-dependent kinase subunit 30A0.046
MybMyb oncogene-like0.046
NiPp1Nuclear inhibitor of Protein phosphatase 10.044
mad2CG17498 gene product from transcript CG17498-RA0.044
aslasterless0.043
gammaTub23Cgamma-Tubulin at 23C0.041
PPP4R2rProtein phosphatase 4 regulatory subunit 2-related protein0.040
Su(var)205Suppressor of variegation 2050.039
Cap-GCG34438 gene product from transcript CG34438-RF0.038
Orc6Origin recognition complex subunit 60.038
dapdacapo0.038
mus209mutagen-sensitive 2090.038
SAKSak kinase0.037
tumtumbleweed0.037
Grip75CG6176 gene product from transcript CG6176-RA0.037
gemininCG3183 gene product from transcript CG3183-RA0.036
Acf1ATP-dependent chromatin assembly factor large subunit0.036
Rca1Regulator of cyclin A10.036
Su(H)Suppressor of Hairless0.036
cdc23CG2508 gene product from transcript CG2508-RA0.036
pngpan gu0.034
AGO2Argonaute 20.034
DetDeterin0.033
gammaTub37Cgamma-Tubulin at 37C0.033
Bap55Brahma associated protein 55kD0.033
CG10722CG10722 gene product from transcript CG10722-RA0.033
Nipped-ACG33554 gene product from transcript CG33554-RE0.033
ballballchen0.032
pavpavarotti0.032
ldslodestar0.032
RanGapRan GTPase activating protein0.031
pluplutonium0.030
DNApol-alpha180DNA polymerase alpha 180kD0.030
SMC1CG6057 gene product from transcript CG6057-RA0.030
prodproliferation disrupter0.030
CG15141CG15141 gene product from transcript CG15141-RA0.030
cnncentrosomin0.030
dpadisc proliferation abnormal0.029
Uch-L3Ubiquitin C-terminal hydrolase0.028
RgaRegena0.028
Cks85ACyclin-dependent kinase subunit 85A0.028
Spc25CG7242 gene product from transcript CG7242-RA0.027
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Foxm1forkhead box M10.292
Top2atopoisomerase (DNA) II alpha0.287
Ccnb1cyclin B10.231
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.221
Plk1polo-like kinase 1 (Drosophila)0.200
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.177
Spag5sperm associated antigen 50.155
Racgap1Rac GTPase-activating protein 10.144
LOC100310874antisense RNA overlapping MCH0.140
Kifc1kinesin family member C10.112
Kif2ckinesin family member 2C0.104
LOC689399hypothetical protein LOC6893990.101
Ppm1bprotein phosphatase 1B, magnesium dependent, beta isoform0.090
Troaptrophinin associated protein0.089
Dlgap5discs, large (Drosophila) homolog-associated protein 50.084
Cdca3cell division cycle associated 30.084
Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.082
Cd82Cd82 molecule0.076
Ccne1cyclin E10.063
Kif22kinesin family member 220.062
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.062
Cenpicentromere protein I0.058
Lbrlamin B receptor0.055
Arfip1ADP-ribosylation factor interacting protein 10.053
Ccnb2cyclin B20.053
Espl1extra spindle pole bodies homolog 1 (S. cerevisiae)0.051
Ckap2cytoskeleton associated protein 20.045
Kif18bkinesin family member 18B0.045
Depdc1DEP domain containing 10.043
Brca2breast cancer 20.041
Btg1B-cell translocation gene 1, anti-proliferative0.041
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.038
Ube2tubiquitin-conjugating enzyme E2T (putative)0.037
Nek9NIMA (never in mitosis gene a)- related kinase 90.037
Kif4kinesin family member 40.035
Hmmrhyaluronan mediated motility receptor (RHAMM)0.035
E2f1E2F transcription factor 10.035
Myh10myosin, heavy chain 10, non-muscle0.034
Uhrf1ubiquitin-like with PHD and ring finger domains 10.033
Cenpfcentromere protein F0.033
Cenptcentromere protein T0.033
Cdkn3cyclin-dependent kinase inhibitor 30.032
Kif20bkinesin family member 20B0.031
Tpm4tropomyosin 40.031
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.031
Ube2cubiquitin-conjugating enzyme E2C0.030
Eif4g2eukaryotic translation initiation factor 4, gamma 20.030
TtkTtk protein kinase0.028
Lamc1laminin, gamma 10.028
Clic4chloride intracellular channel 40.028
Arf6ADP-ribosylation factor 60.028
Nr3c2nuclear receptor subfamily 3, group C, member 20.028
Cd44Cd44 molecule0.026
Ubl3ubiquitin-like 30.026
Pds5aPDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)0.026
Dlg1discs, large homolog 1 (Drosophila)0.025
Mbd2methyl-CpG binding domain protein 20.025
Zfp364zinc finger protein 3640.025
Slain2SLAIN motif family, member 20.024
Eif5beukaryotic translation initiation factor 5B0.024
Mcm5minichromosome maintenance complex component 50.024
Gins4GINS complex subunit 4 (Sld5 homolog)0.024
Bard1BRCA1 associated RING domain 10.023
Ect2epithelial cell transforming sequence 2 oncogene0.023
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.023
Birc5baculoviral IAP repeat-containing 50.023
Melkmaternal embryonic leucine zipper kinase0.023
Haus4HAUS augmin-like complex, subunit 40.023
Ppp4r2protein phosphatase 4, regulatory subunit 20.022
Ptp4a2protein tyrosine phosphatase 4a20.022
Myo1bmyosin Ib0.022
Nuf2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.022
Tpm3tropomyosin 3, gamma0.022
TraipTRAF-interacting protein0.022
Eif2c2eukaryotic translation initiation factor 2C, 20.022
Aurkbaurora kinase B0.022
Znf76zinc finger protein 76 (expressed in testis)0.022
Brca1breast cancer 10.022
Depdc1bDEP domain containing 1B0.022
Taok1TAO kinase 10.022
Top2btopoisomerase (DNA) II beta0.022
Ncapd2non-SMC condensin I complex, subunit D20.021
Stk17bserine/threonine kinase 17b0.021
Cdk1cyclin-dependent kinase 10.021
Cd24CD24 molecule0.021
Pdpk13-phosphoinositide dependent protein kinase-10.021
Gna12guanine nucleotide binding protein (G protein) alpha 120.020
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.020
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.020
PbkPDZ binding kinase0.020
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.020
Cdca2cell division cycle associated 20.020
Litaflipopolysaccharide-induced TNF factor0.020
Man1a1mannosidase, alpha, class 1A, member 10.020
Bcrbreakpoint cluster region0.020
Dhfrdihydrofolate reductase0.019
Tjp2tight junction protein 20.019
Ccnfcyclin F0.019
Ndrg2N-myc downstream regulated gene 20.019
Plk4polo-like kinase 4 (Drosophila)0.019
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC27Cdc27p0.997
CDC16Cdc16p0.991
CDC20Cdc20p0.986
PPH21Pph21p0.982
DOC1Doc1p0.977
CDC26Cdc26p0.969
SLK19Slk19p0.964
MTW1Mtw1p0.939
SLI15Sli15p0.919
MAD2Mad2p0.917
APC2Apc2p0.884
NSL1Nsl1p0.874
CDC23Cdc23p0.855
TID3Tid3p0.839
SPC105Spc105p0.839
BUB1Bub1p0.797
CSE4Cse4p0.783
CDC55Cdc55p0.777
APC4Apc4p0.776
BUB3Bub3p0.775
CHL4Chl4p0.771
SMC4Smc4p0.756
DSN1Dsn1p0.706
MND2Mnd2p0.697
PPH22Pph22p0.651
IML3Iml3p0.614
PPZ1Ppz1p0.556
KIP1Kip1p0.469
TIP41Tip41p0.464
SPC24Spc24p0.439
MCM21Mcm21p0.437
MPS1Mps1p0.433
HHT1Hht1p0.407
MIF2Mif2p0.401
PDS1Pds1p0.400
CTF3Ctf3p0.336
APC1Apc1p0.297
MAD3Mad3p0.287
SWM1Swm1p0.275
GLC7Glc7p0.265
PSH1Psh1p0.262
YPI1Ypi1p0.255
HHF2Hhf2p0.249
NUF2Nuf2p0.246
HTA1Hta1p0.236
ASE1Ase1p0.219
MAD1Mad1p0.197
CIN8Cin8p0.196
BIR1Bir1p0.191
AME1Ame1p0.188
CBF2Cbf2p0.186
CDH1Cdh1p0.168
GIP2Gip2p0.156
IPL1Ipl1p0.155
YBP2Ybp2p0.144
SMC6Smc6p0.135
APC5Apc5p0.134
KIC1Kic1p0.121
FMP48Fmp48p0.117
MCM22Mcm22p0.105
APC11Apc11p0.098
SPC25Spc25p0.097
OKP1Okp1p0.095
NNF1Nnf1p0.094
SMC2Smc2p0.078
SDS22Sds22p0.078
RTS1Rts1p0.073
GLG1Glg1p0.065
PIG2Pig2p0.061
BRN1Brn1p0.060
APC9Apc9p0.060
CTF19Ctf19p0.058
DAM1Dam1p0.058
CTF13Ctf13p0.057
ESP1Esp1p0.057
MMS21Mms21p0.053
PKC1Pkc1p0.053
ECO1Eco1p0.052
RAD53Rad53p0.051
CBF1Cbf1p0.046
RDH54Rdh54p0.046
PTI1Pti1p0.045
NBL1Nbl1p0.044
NSE5Nse5p0.041
MYO1Myo1p0.040
KEL1Kel1p0.039
IRC15Irc15p0.035
SMC5Smc5p0.035
KRE29Kre29p0.034
EAF1Eaf1p0.034
VIK1Vik1p0.032
CAB3Cab3p0.032
SPC110Spc110p0.031
HTB1Htb1p0.031
YKL075Chypothetical protein0.030
VHS2Vhs2p0.029
RPT4Rpt4p0.028
FIN1Fin1p0.028
SPO14Spo14p0.027
RPN14Rpn14p0.027