The network for 'regulation of phosphatase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of phosphatase activity

Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

NameDescriptionProbabilityFunc Analog Organism
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.908
FHL2four and a half LIM domains 20.843
ANKRD28ankyrin repeat domain 280.750
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.674
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.624
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.596
PTPRCprotein tyrosine phosphatase, receptor type, C0.528
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.525
AKT1v-akt murine thymoma viral oncogene homolog 10.487
ACTBactin, beta0.468
BIRC2baculoviral IAP repeat containing 20.389
RIPK3receptor-interacting serine-threonine kinase 30.363
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.342
ANKRD52ankyrin repeat domain 520.321
MAP3K3mitogen-activated protein kinase kinase kinase 30.276
ENGendoglin0.276
PFN1profilin 10.274
AFF4AF4/FMR2 family, member 40.266
TSC2tuberous sclerosis 20.235
BIRC3baculoviral IAP repeat containing 30.228
TSSK2testis-specific serine kinase 20.213
TP53BP2tumor protein p53 binding protein, 20.202
PPP6Cprotein phosphatase 6, catalytic subunit0.199
GDAguanine deaminase0.192
CASC5cancer susceptibility candidate 50.174
BMPR1Abone morphogenetic protein receptor, type IA0.157
MPRIPmyosin phosphatase Rho interacting protein0.150
WWP2WW domain containing E3 ubiquitin protein ligase 20.149
CDH5cadherin 5, type 2 (vascular endothelium)0.145
KLHL3kelch-like 3 (Drosophila)0.144
NRP1neuropilin 10.144
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.143
TCTEX1D4Tctex1 domain containing 40.141
KIAA1683KIAA16830.136
PTENphosphatase and tensin homolog0.133
ZFYVE9zinc finger, FYVE domain containing 90.127
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.123
ADRB1adrenergic, beta-1-, receptor0.123
FSTL1follistatin-like 10.121
EAF1ELL associated factor 10.118
TFF1trefoil factor 10.116
ACVR1Bactivin A receptor, type IB0.113
LATlinker for activation of T cells0.110
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.102
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.101
CFL1cofilin 1 (non-muscle)0.099
KIAA1949KIAA19490.096
PPP1R8protein phosphatase 1, regulatory (inhibitor) subunit 80.095
PXNpaxillin0.094
BCL2L1BCL2-like 10.093
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.088
ADORA2Aadenosine A2a receptor0.087
CDK1cyclin-dependent kinase 10.086
MYO10myosin X0.086
CDHR2cadherin-related family member 20.084
PPP1R10protein phosphatase 1, regulatory (inhibitor) subunit 100.077
TGFBR1transforming growth factor, beta receptor 10.074
PBKPDZ binding kinase0.073
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.073
SHC2SHC (Src homology 2 domain containing) transforming protein 20.072
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.070
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.068
SNF8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.067
SORBS1sorbin and SH3 domain containing 10.066
PPP4Cprotein phosphatase 4, catalytic subunit0.065
PLXND1plexin D10.065
TBC1D17TBC1 domain family, member 170.062
PKM2pyruvate kinase, muscle0.062
PGFplacental growth factor0.060
RANBP9RAN binding protein 90.060
RLN3relaxin 30.059
TRAF1TNF receptor-associated factor 10.059
ITGALintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)0.059
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.059
CCND3cyclin D30.059
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.058
VEGFAvascular endothelial growth factor A0.058
PPP1R15Bprotein phosphatase 1, regulatory (inhibitor) subunit 15B0.058
ZBTB16zinc finger and BTB domain containing 160.057
GAS7growth arrest-specific 70.057
SKA3spindle and kinetochore associated complex subunit 30.056
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.055
SPTBN1spectrin, beta, non-erythrocytic 10.055
C11orf66chromosome 11 open reading frame 660.054
STAU1staufen, RNA binding protein, homolog 1 (Drosophila)0.053
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.051
LDLRlow density lipoprotein receptor0.051
CAPZBcapping protein (actin filament) muscle Z-line, beta0.050
FANCCFanconi anemia, complementation group C0.049
PPP1R13Bprotein phosphatase 1, regulatory (inhibitor) subunit 13B0.048
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.048
TANKTRAF family member-associated NFKB activator0.047
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.046
CD33CD33 molecule0.046
INSRinsulin receptor0.046
BAI1brain-specific angiogenesis inhibitor 10.046
PDIA6protein disulfide isomerase family A, member 60.046
LCKlymphocyte-specific protein tyrosine kinase0.046
MAPK1mitogen-activated protein kinase 10.046
KITLGKIT ligand0.045
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
TorTarget of rapamycin0.317
enaenabled0.203
didumdilute class unconventional myosin0.166
lolalongitudinals lacking0.130
Lis-1Lissencephaly-10.108
stanstarry night0.105
Src64BSrc oncogene at 64B0.102
mei-P26CG12218 gene product from transcript CG12218-RA0.081
WWrinkled0.078
fzfrizzled0.076
jumujumeau0.072
mRpL49mitochondrial ribosomal protein L490.072
Fmr1CG6203 gene product from transcript CG6203-RC0.071
AtpalphaNa pump alpha subunit0.071
BicDBicaudal D0.069
pumpumilio0.063
slikSterile20-like kinase0.061
psqpipsqueak0.059
JIL-1CG6297 gene product from transcript CG6297-RA0.058
BEAF-32Boundary element-associated factor of 32kD0.058
dpdumpy0.056
mtsmicrotubule star0.056
lealeak0.053
Rm62CG10279 gene product from transcript CG10279-RD0.052
MhcMyosin heavy chain0.052
sesBstress-sensitive B0.051
chicchickadee0.051
roboroundabout0.050
bonbonus0.049
fz2frizzled 20.048
chicoCG5686 gene product from transcript CG5686-RB0.047
Arf51FADP ribosylation factor 51F0.046
DscamDown syndrome cell adhesion molecule0.045
CG11699CG11699 gene product from transcript CG11699-RA0.045
CG3731CG3731 gene product from transcript CG3731-RA0.044
phlpole hole0.044
flflfalafel0.043
fwfurrowed0.043
gwlgreatwall0.042
su(f)suppressor of forked0.042
Rho1CG8416 gene product from transcript CG8416-RB0.042
CG8680CG8680 gene product from transcript CG8680-RA0.041
ftz-f1ftz transcription factor 10.041
Bx42CG8264 gene product from transcript CG8264-RA0.041
traltrailer hitch0.040
shishibire0.039
Syx7Syntaxin 70.038
glglass0.038
wgwingless0.038
Pp1-87BProtein phosphatase 1 at 87B0.037
nejnejire0.037
ecdecdysoneless0.037
AblAbl tyrosine kinase0.037
PcPolycomb0.036
crccryptocephal0.036
Tsc1CG6147 gene product from transcript CG6147-RA0.036
spinspinster0.036
Pink1PTEN-induced putative kinase 10.036
HsfHeat shock factor0.036
VangVan Gogh0.035
CG14818CG14818 gene product from transcript CG14818-RA0.035
Caf1Chromatin assembly factor 1 subunit0.035
C3GCG42328 gene product from transcript CG42328-RC0.035
PepProtein on ecdysone puffs0.035
mmymummy0.035
Gem3Gemin30.034
Pka-R1cAMP-dependent protein kinase R10.033
frufruitless0.033
cswcorkscrew0.033
CspCysteine string protein0.033
CG1074CG1074 gene product from transcript CG1074-RA0.032
dncdunce0.032
E2f2E2F transcription factor 20.032
bcdbicoid0.032
CG6843CG6843 gene product from transcript CG6843-RA0.032
CG2116CG2116 gene product from transcript CG2116-RA0.032
CG3689CG3689 gene product from transcript CG3689-RB0.032
nosnanos0.031
RpS17Ribosomal protein S170.031
benbendless0.031
pds5CG17509 gene product from transcript CG17509-RA0.031
LLobe0.031
ggarnet0.030
par-6CG5884 gene product from transcript CG5884-RA0.030
rlrolled0.030
KhcKinesin heavy chain0.030
ckcrinkled0.029
fl(2)dfemale lethal d0.029
Myt1CG32417 gene product from transcript CG32417-RA0.029
commcommissureless0.029
cgcombgap0.029
UbxUltrabithorax0.029
wgewinged eye0.029
PpD3Protein phosphatase D30.029
LamLamin0.029
salmspalt major0.029
dppdecapentaplegic0.029
DlDelta0.029
mskmoleskin0.028
nmonemo0.028
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Map3k14mitogen-activated protein kinase kinase kinase 140.452
Tnftumor necrosis factor0.292
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.204
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.184
FasFas (TNF receptor superfamily member 6)0.175
Ifnginterferon gamma0.135
Dlg4discs, large homolog 4 (Drosophila)0.124
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.105
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.097
Nos3nitric oxide synthase 3, endothelial cell0.094
Hand2heart and neural crest derivatives expressed transcript 20.084
Hdac4histone deacetylase 40.080
Acvr1activin A receptor, type 10.079
Leprleptin receptor0.078
Apcadenomatosis polyposis coli0.077
Il7interleukin 70.075
Hspa5heat shock protein 50.075
Toxthymocyte selection-associated high mobility group box0.074
Ltblymphotoxin B0.074
Lrp1low density lipoprotein receptor-related protein 10.067
Il2rginterleukin 2 receptor, gamma chain0.065
Lyz2lysozyme 20.058
Cxcr5chemokine (C-X-C motif) receptor 50.055
Il10interleukin 100.054
Ltalymphotoxin A0.049
Cxcl13chemokine (C-X-C motif) ligand 130.044
Bmp4bone morphogenetic protein 40.041
Mef2dmyocyte enhancer factor 2D0.038
Tgfbr2transforming growth factor, beta receptor II0.036
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.034
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.033
Nf2neurofibromatosis 20.032
Ikzf1IKAROS family zinc finger 10.031
Prrx1paired related homeobox 10.027
Mef2cmyocyte enhancer factor 2C0.027
Cd40CD40 antigen0.026
Manfmesencephalic astrocyte-derived neurotrophic factor0.023
Zeb2zinc finger E-box binding homeobox 20.023
Agtr2angiotensin II receptor, type 20.023
Rab25RAB25, member RAS oncogene family0.023
Il2interleukin 20.023
Tsc2tuberous sclerosis 20.022
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.021
Creld2cysteine-rich with EGF-like domains 20.021
Snap25synaptosomal-associated protein 250.021
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.020
Plxna4plexin A40.020
Hdac5histone deacetylase 50.020
Col4a3collagen, type IV, alpha 30.020
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.019
FynFyn proto-oncogene0.019
Trp53transformation related protein 530.019
Csf1colony stimulating factor 1 (macrophage)0.018
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.017
Nrcamneuron-glia-CAM-related cell adhesion molecule0.016
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.016
Bcl3B-cell leukemia/lymphoma 30.016
Cdkn1bcyclin-dependent kinase inhibitor 1B0.015
Ptpn12protein tyrosine phosphatase, non-receptor type 120.015
Ptenphosphatase and tensin homolog0.015
Casp8caspase 80.015
Tlr2toll-like receptor 20.014
Nf1neurofibromatosis 10.014
Rag1recombination activating gene 10.013
Hspa1aheat shock protein 1A0.013
Hand1heart and neural crest derivatives expressed transcript 10.013
Il6stinterleukin 6 signal transducer0.013
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.013
Cd19CD19 antigen0.013
TcraT-cell receptor alpha chain0.013
Gucy1a3guanylate cyclase 1, soluble, alpha 30.012
Ppargc1bperoxisome proliferative activated receptor, gamma, coactivator 1 beta0.012
Il4interleukin 40.012
Ptgs2prostaglandin-endoperoxide synthase 20.012
Esr1estrogen receptor 1 (alpha)0.012
Gja1gap junction protein, alpha 10.012
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.012
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.012
Retret proto-oncogene0.012
Id2inhibitor of DNA binding 20.012
Eif2c2eukaryotic translation initiation factor 2C, 20.011
Adam17a disintegrin and metallopeptidase domain 170.011
Cd44CD44 antigen0.011
Ptprcprotein tyrosine phosphatase, receptor type, C0.011
Gucy1b3guanylate cyclase 1, soluble, beta 30.011
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.011
Igbp1immunoglobulin (CD79A) binding protein 10.011
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.011
Cntn1contactin 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TFG2Tfg2p0.014