The network for 'regulation of tumor necrosis factor mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of tumor necrosis factor mediated signaling pathway

Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.

NameDescriptionProbabilityFunc Analog Organism
ZNF43zinc finger protein 430.989
C1QAcomplement component 1, q subcomponent, A chain0.962
ZNF675zinc finger protein 6750.813
ZNF273zinc finger protein 2730.747
ZNF253zinc finger protein 2530.722
TRAF6TNF receptor-associated factor 60.502
C1QCcomplement component 1, q subcomponent, C chain0.418
IRAK1interleukin-1 receptor-associated kinase 10.376
ZNF680zinc finger protein 6800.351
ZNF85zinc finger protein 850.315
RNF31ring finger protein 310.259
ZNF708zinc finger protein 7080.253
ZNF93zinc finger protein 930.205
ZNF117zinc finger protein 1170.201
ZNF254zinc finger protein 2540.164
ZNF91zinc finger protein 910.147
ZNF430zinc finger protein 4300.134
ZNF746zinc finger protein 7460.129
GHRgrowth hormone receptor0.109
C1QBcomplement component 1, q subcomponent, B chain0.105
AXLAXL receptor tyrosine kinase0.077
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.076
RASSF5Ras association (RalGDS/AF-6) domain family member 50.074
APOC1apolipoprotein C-I0.059
NLRC4NLR family, CARD domain containing 40.055
ZNF107zinc finger protein 1070.054
SQSTM1sequestosome 10.053
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.042
IRAK2interleukin-1 receptor-associated kinase 20.041
ZNF92zinc finger protein 920.040
MEFVMediterranean fever0.034
TOX4TOX high mobility group box family member 40.026
MDFIMyoD family inhibitor0.022
ZNF682zinc finger protein 6820.020
LCATlecithin-cholesterol acyltransferase0.020
ZNF195zinc finger protein 1950.018
EP300E1A binding protein p3000.015
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.014
MAP3K14mitogen-activated protein kinase kinase kinase 140.014
SNIP1Smad nuclear interacting protein 10.014
CAV1caveolin 1, caveolae protein, 22kDa0.014
ZNF506zinc finger protein 5060.012
DCAF7DDB1 and CUL4 associated factor 70.011
SHARPINSHANK-associated RH domain interactor0.011
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gbp5guanylate binding protein 50.169
Mdm2transformed mouse 3T3 cell double minute 20.073
Rnf31ring finger protein 310.031
Eya2eyes absent 2 homolog (Drosophila)0.029
SharpinSHANK-associated RH domain interacting protein0.019
Sncaipsynuclein, alpha interacting protein (synphilin)0.013
Lyz2lysozyme 20.011
Aim2absent in melanoma 20.011
NsfN-ethylmaleimide sensitive fusion protein0.011
Mfn2mitofusin 20.010
Rbck1RanBP-type and C3HC4-type zinc finger containing 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism