The network for 'regulation of actin filament based movement' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of actin filament based movement

Any process that modulates the frequency, rate or extent of actin filament-based movement.

NameDescriptionProbabilityFunc Analog Organism
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.976
KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 10.952
MPZL2myelin protein zero-like 20.902
JUPjunction plakoglobin0.870
DLG4discs, large homolog 4 (Drosophila)0.859
DSC2desmocollin 20.852
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.835
KCNE1potassium voltage-gated channel, Isk-related family, member 10.831
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 10.817
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.758
DSG2desmoglein 20.711
MPZL3myelin protein zero-like 30.711
ACTN2actinin, alpha 20.691
SCN5Asodium channel, voltage-gated, type V, alpha subunit0.662
KCNIP2Kv channel interacting protein 20.641
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.640
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.576
SNTG2syntrophin, gamma 20.538
MAPK12mitogen-activated protein kinase 120.529
LIN7Blin-7 homolog B (C. elegans)0.500
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.460
TNNI1troponin I type 1 (skeletal, slow)0.434
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.402
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.402
KRT14keratin 140.251
SPTBspectrin, beta, erythrocytic0.247
PSEN1presenilin 10.229
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.219
CTNND1catenin (cadherin-associated protein), delta 10.212
ESR2estrogen receptor 2 (ER beta)0.206
PKP3plakophilin 30.202
APCadenomatous polyposis coli0.198
CDH3cadherin 3, type 1, P-cadherin (placental)0.189
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.142
CLCN3chloride channel 30.129
ERBB2IPerbb2 interacting protein0.120
LAD1ladinin 10.102
DTNAdystrobrevin, alpha0.097
TRIM29tripartite motif containing 290.093
PTPRJprotein tyrosine phosphatase, receptor type, J0.091
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.075
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.071
CTNNBIP1catenin, beta interacting protein 10.066
ADAM11ADAM metallopeptidase domain 110.066
PDCD6programmed cell death 60.059
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.054
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.053
GJB3gap junction protein, beta 3, 31kDa0.052
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.050
DSC3desmocollin 30.049
TNNT2troponin T type 2 (cardiac)0.049
AKAP6A kinase (PRKA) anchor protein 60.044
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.043
KCNC1potassium voltage-gated channel, Shaw-related subfamily, member 10.042
GLE1GLE1 RNA export mediator homolog (yeast)0.041
FRMD5FERM domain containing 50.039
KCNIP1Kv channel interacting protein 10.036
TBX5T-box 50.036
SERPINB5serpin peptidase inhibitor, clade B (ovalbumin), member 50.036
TNNC1troponin C type 1 (slow)0.036
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.036
PKP2plakophilin 20.036
RHAGRh-associated glycoprotein0.035
SLC9A3R2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.035
DSG1desmoglein 10.035
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.035
ZFYVE9zinc finger, FYVE domain containing 90.033
KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 20.032
SPINT1serine peptidase inhibitor, Kunitz type 10.032
BAI1brain-specific angiogenesis inhibitor 10.032
CDH15cadherin 15, type 1, M-cadherin (myotubule)0.031
FRS2fibroblast growth factor receptor substrate 20.030
ARHGEF40Rho guanine nucleotide exchange factor (GEF) 400.029
DLGAP1discs, large (Drosophila) homolog-associated protein 10.028
ARVCFarmadillo repeat gene deleted in velocardiofacial syndrome0.028
EHD1EH-domain containing 10.028
ATP2B3ATPase, Ca++ transporting, plasma membrane 30.027
BTRCbeta-transducin repeat containing0.027
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.026
GJB5gap junction protein, beta 5, 31.1kDa0.026
KCNH1potassium voltage-gated channel, subfamily H (eag-related), member 10.026
GNB2guanine nucleotide binding protein (G protein), beta polypeptide 20.025
KCNB2potassium voltage-gated channel, Shab-related subfamily, member 20.024
MYOZ1myozenin 10.023
PDZK1PDZ domain containing 10.023
MYL2myosin, light chain 2, regulatory, cardiac, slow0.022
KRT6Bkeratin 6B0.022
DSG3desmoglein 30.022
IRF6interferon regulatory factor 60.021
COL17A1collagen, type XVII, alpha 10.021
TNNI3troponin I type 3 (cardiac)0.021
PECAM1platelet/endothelial cell adhesion molecule0.021
ITGB4integrin, beta 40.020
DPP6dipeptidyl-peptidase 60.020
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.020
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.588
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.523
dsc2ldesmocollin 2 like0.361
atp1a1a.3ATPase, Na+/K+ transporting, alpha 1a.3 polypeptide0.300
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.279
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.263
tnnt2atroponin T2a, cardiac0.219
xirp1xin actin-binding repeat containing 10.213
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.208
actn2actinin, alpha 20.195
anxa11bannexin A11b0.167
ca2carbonic anhydrase II0.167
trpm7transient receptor potential cation channel, subfamily M, member 70.160
krt8keratin 80.153
mybpc3myosin binding protein C, cardiac0.140
adrb2aadrenergic receptor, beta 2a0.133
LOC100000433hypothetical LOC1000004330.110
dspadesmoplakin a0.099
synpo2lbsynaptopodin 2-like b0.096
pvalb8parvalbumin 80.092
jupjunction plakoglobin0.086
sdprbserum deprivation response b0.085
bcl2l1bcl2-like 10.084
perpPERP, TP53 apoptosis effector0.073
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.070
pmaip1phorbol-12-myristate-13-acetate-induced protein 10.067
foxi3aforkhead box I3a0.067
pvalb7parvalbumin 70.065
LOC567131calcitonin gene-related peptide type 1 receptor-like0.063
serinc2serine incorporator 20.061
cabp1calcium binding protein 10.059
scn12absodium channel, voltage gated, type XII, alpha b0.059
kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.058
adrb2badrenergic receptor, beta 2b0.050
anxa11aannexin A11a0.048
rassf7bRas association (RalGDS/AF-6) domain family (N-terminal) member 7b0.048
kcnq1potassium voltage-gated channel, KQT-like subfamily, member 10.044
atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.043
hmgn3high mobility group nucleosomal binding domain 30.043
ppargperoxisome proliferator activated receptor gamma0.042
lifrbleukemia inhibitory factor receptor alpha b0.041
agr2anterior gradient homolog 2 (Xenopus laevis)0.040
zerg24potassium voltage-gated channel zerg240.039
hmgn2high-mobility group nucleosomal binding domain 20.038
scn4basodium channel, voltage-gated, type IV, beta a0.038
fhlafour and a half LIM domains a0.037
tnnc1btroponin C type 1b (slow)0.037
ripk4receptor-interacting serine-threonine kinase 40.037
krt18keratin 180.037
LOC566708FL cytokine receptor-like0.036
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.035
il8interleukin 80.032
pygmbphosphorylase, glycogen (muscle) b0.032
ucp3uncoupling protein 30.031
abca12ATP-binding cassette, sub-family A (ABC1), member 120.031
gipc2GIPC PDZ domain containing family, member 20.029
atp6v1alATPase, H+ transporting, lysosomal V1 subunit A, like0.029
slc15a2solute carrier family 15 (H+/peptide transporter), member 20.028
igfbp3insulin-like growth factor binding protein 30.028
cfdlcomplement factor D (adipsin) like0.028
ppargc1alperoxisome proliferator-activated receptor gamma, coactivator 1 alpha like0.027
slc38a3solute carrier family 38, member 30.027
pkp3plakophilin 30.027
plekha7pleckstrin homology domain containing, family A member 70.026
atp1a1a.5ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide0.026
dsg2desmoglein 20.026
actc1aactin, alpha, cardiac muscle 1a0.026
cldnbclaudin b0.025
ddtD-dopachrome tautomerase0.025
LOC796298isotocin receptor-like 10.024
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.024
eef2l2eukaryotic translation elongation factor 2, like 20.024
rbm24aRNA binding motif protein 24a0.023
scn3bsodium channel, voltage-gated, type III, beta0.023
nuak2NUAK family, SNF1-like kinase, 20.023
usp2aubiquitin specific peptidase 2a0.021
nr3c2nuclear receptor subfamily 3, group C, member 20.021
pvrl1bpoliovirus receptor-related 1b0.021
rhcgbRhesus blood group, C glycoprotein b0.021
flot1bflotillin 1b0.020
LOC100331455arf-GAP with dual PH domain-containing protein 2-like0.020
pmelapremelanosome protein a0.020
mycbp2MYC binding protein 20.020
mitfbmicrophthalmia-associated transcription factor b0.019
csrp3cysteine and glycine-rich protein 3 (cardiac LIM protein)0.019
ryr3ryanodine receptor 30.019
lmo7aLIM domain only 7a0.019
net1neuroepithelial cell transforming gene 10.019
scn2bsodium channel, voltage-gated, type II, beta0.019
pgam2phosphoglycerate mutase 2 (muscle)0.019
slc24a5solute carrier family 24, member 50.018
eya4eyes absent homolog 4 (Drosophila)0.018
sept2septin 20.017
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Scn5asodium channel, voltage-gated, type V, alpha0.877
Ryr2ryanodine receptor 2, cardiac0.623
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.229
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.156
Tbx5T-box 50.100
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.087
Tjp1tight junction protein 10.084
Kcnj10potassium inwardly-rectifying channel, subfamily J, member 100.070
Scn1asodium channel, voltage-gated, type I, alpha0.064
Gja1gap junction protein, alpha 10.060
Nedd4lneural precursor cell expressed, developmentally down-regulated gene 4-like0.040
Dmddystrophin, muscular dystrophy0.039
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.035
Myom2myomesin 20.030
Rnf112ring finger protein 1120.030
Kcnk3potassium channel, subfamily K, member 30.027
Dsg2desmoglein 20.026
Ldb3LIM domain binding 30.025
Casq2calsequestrin 20.024
Tnni2troponin I, skeletal, fast 20.023
Hrchistidine rich calcium binding protein0.023
Cdh23cadherin 23 (otocadherin)0.021
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.021
Mybpc3myosin binding protein C, cardiac0.020
Pygmmuscle glycogen phosphorylase0.020
Nos3nitric oxide synthase 3, endothelial cell0.020
Dsc1desmocollin 10.019
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.019
Xirp1xin actin-binding repeat containing 10.019
Epas1endothelial PAS domain protein 10.018
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.017
Itga7integrin alpha 70.017
Cacna2d2calcium channel, voltage-dependent, alpha 2/delta subunit 20.017
Dtnadystrobrevin alpha0.017
Actn2actinin alpha 20.016
Spna1spectrin alpha 10.014
SpegSPEG complex locus0.013
Cldn3claudin 30.013
Tcfap2ctranscription factor AP-2, gamma0.013
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.013
Myh7myosin, heavy polypeptide 7, cardiac muscle, beta0.013
Tbx3T-box 30.012
PerpPERP, TP53 apoptosis effector0.012
Add2adducin 2 (beta)0.012
Park2Parkinson disease (autosomal recessive, juvenile) 2, parkin0.012
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.011
Klk6kallikrein related-peptidase 60.011
Esrrbestrogen related receptor, beta0.011
Dmpkdystrophia myotonica-protein kinase0.011
Ckmt2creatine kinase, mitochondrial 20.011
Cdh4cadherin 40.011
Fut2fucosyltransferase 20.011
Fgf1fibroblast growth factor 10.011
Hrh2histamine receptor H20.011
Mmp15matrix metallopeptidase 150.011
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.011
Cxadrcoxsackie virus and adenovirus receptor0.011
Pcdh12protocadherin 120.010
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.010
Hey2hairy/enhancer-of-split related with YRPW motif 20.010
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.010
Sstr3somatostatin receptor 30.010
Pacsin1protein kinase C and casein kinase substrate in neurons 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.339
Casq2calsequestrin 2 (cardiac muscle)0.302
LOC100362824caveolin 2-like0.277
Kcnk3potassium channel, subfamily K, member 30.169
Ckmcreatine kinase, muscle0.160
Fgf14fibroblast growth factor 140.139
Fgf16fibroblast growth factor 160.135
Grik3glutamate receptor, ionotropic, kainate 30.127
Slc6a17solute carrier family 6 (neurotransmitter transporter), member 170.109
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.102
Scn5asodium channel, voltage-gated, type V, alpha subunit0.096
Fitm1fat storage-inducing transmembrane protein 10.090
Dhrs7cdehydrogenase/reductase (SDR family) member 7C0.090
Dccdeleted in colorectal carcinoma0.079
Fabp6fatty acid binding protein 6, ileal0.078
Atxn1ataxin 10.067
Rpl3lribosomal protein L3-like0.065
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.065
Slc8a1solute carrier family 8 (sodium/calcium exchanger), member 10.061
Slc14a2solute carrier family 14 (urea transporter), member 20.061
Tnni1troponin I type 1 (skeletal, slow)0.061
Gria1glutamate receptor, ionotropic, AMPA 10.060
Epha8Eph receptor A80.059
RGD1309036hypothetical LOC2928740.057
Appamyloid beta (A4) precursor protein0.055
Ampd1adenosine monophosphate deaminase 1 (isoform M)0.051
Csrp3cysteine and glycine-rich protein 30.050
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.050
Nos3nitric oxide synthase 3, endothelial cell0.048
Prdm2PR domain containing 2, with ZNF domain0.047
Gcm1glial cells missing homolog 1 (Drosophila)0.047
Gata6GATA binding protein 60.045
Prkg2protein kinase, cGMP-dependent, type II0.044
Inhbainhibin beta-A0.044
Pygmphosphorylase, glycogen, muscle0.040
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.039
Kcnq2potassium voltage-gated channel, KQT-like subfamily, member 20.038
Sctrsecretin receptor0.037
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.037
Inhainhibin alpha0.036
Ednraendothelin receptor type A0.036
Dlg4discs, large homolog 4 (Drosophila)0.035
Pgcprogastricsin (pepsinogen C)0.035
Tpsb2tryptase beta 20.034
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.034
Abcc8ATP-binding cassette, subfamily C (CFTR/MRP), member 80.033
Myoz2myozenin 20.033
Apobec2apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 20.032
Msx2msh homeobox 20.032
Pla2g5phospholipase A2, group V0.031
Glra1glycine receptor, alpha 10.031
Muskmuscle, skeletal, receptor tyrosine kinase0.030
Scn2bsodium channel, voltage-gated, type II, beta0.030
Gja3gap junction protein, alpha 30.030
Myl1myosin, light chain 10.030
Ehfets homologous factor0.030
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.029
Bglapbone gamma-carboxyglutamate (gla) protein0.029
Galr1galanin receptor 10.028
Ppardperoxisome proliferator-activated receptor delta0.028
Figfc-fos induced growth factor0.028
Actc1actin, alpha, cardiac muscle 10.027
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.027
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.026
Kcna5potassium voltage-gated channel, shaker-related subfamily, member 50.026
Glp1rglucagon-like peptide 1 receptor0.026
Fgf7fibroblast growth factor 70.025
Kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.025
Vom1r90vomeronasal 1 receptor 900.025
Tmem38atransmembrane protein 38a0.025
Gad2glutamate decarboxylase 20.024
Wt1Wilms tumor 10.024
Gabrpgamma-aminobutyric acid (GABA-A) receptor, pi0.024
Rims1regulating synaptic membrane exocytosis 10.024
Prkcaprotein kinase C, alpha0.024
Wipf3WAS/WASL interacting protein family, member 30.023
Myoz1myozenin 10.023
Mchr1melanin-concentrating hormone receptor 10.023
Lim2lens intrinsic membrane protein 20.023
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.023
Olr416olfactory receptor 4160.023
Obscnobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.023
Cav3caveolin 30.022
Cd46CD46 molecule, complement regulatory protein0.022
Maoamonoamine oxidase A0.022
Ryr2ryanodine receptor 2, cardiac0.022
Myl3myosin, light chain 3, alkali; ventricular, skeletal, slow0.021
Adcy5adenylate cyclase 50.021
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.021
Gnb3guanine nucleotide binding protein (G protein), beta polypeptide 30.021
Ucp3uncoupling protein 3 (mitochondrial, proton carrier)0.021
Prkag3protein kinase, AMP-activated, gamma 3 non-catalytic subunit0.020
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.019
Gabra3gamma-aminobutyric acid (GABA) A receptor, alpha 30.019
Ros1c-ros oncogene 1 , receptor tyrosine kinase0.018
Rph3arabphilin 3A0.018
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism