The network for 'arf protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

arf protein signal transduction

A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.

NameDescriptionProbabilityFunc Analog Organism
SH3KBP1SH3-domain kinase binding protein 10.964
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.781
MAP3K5mitogen-activated protein kinase kinase kinase 50.546
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.531
PXNpaxillin0.293
CTTNcortactin0.134
COPGcoatomer protein complex, subunit gamma0.084
ARFIP2ADP-ribosylation factor interacting protein 20.083
BCAR1breast cancer anti-estrogen resistance 10.077
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.046
PTK2PTK2 protein tyrosine kinase 20.040
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.039
EEF1Geukaryotic translation elongation factor 1 gamma0.036
HGShepatocyte growth factor-regulated tyrosine kinase substrate0.032
SPRR2Asmall proline-rich protein 2A0.025
SPRY2sprouty homolog 2 (Drosophila)0.024
PDCD6IPprogrammed cell death 6 interacting protein0.024
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.022
FYNFYN oncogene related to SRC, FGR, YES0.018
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.018
CD2APCD2-associated protein0.017
ADAM15ADAM metallopeptidase domain 150.017
SUPT6Hsuppressor of Ty 6 homolog (S. cerevisiae)0.016
WBP11WW domain binding protein 110.015
CYTH2cytohesin 20.014
CFL1cofilin 1 (non-muscle)0.013
SH3BP2SH3-domain binding protein 20.013
PTK2BPTK2B protein tyrosine kinase 2 beta0.013
SQSTM1sequestosome 10.013
HMGXB3HMG box domain containing 30.013
NCK2NCK adaptor protein 20.013
C4orf14chromosome 4 open reading frame 140.012
MAP3K4mitogen-activated protein kinase kinase kinase 40.012
GGA1golgi-associated, gamma adaptin ear containing, ARF binding protein 10.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Arf79FADP ribosylation factor 79F0.731
Arc-p34CG10954 gene product from transcript CG10954-RA0.038
effeffete0.028
CG2316CG2316 gene product from transcript CG2316-RD0.021
Rab7Rab-protein 70.020
deltaCOPdelta-coatomer protein0.014
CG6838CG6838 gene product from transcript CG6838-RC0.014
ifcinfertile crescent0.013
Cnx99ACalnexin 99A0.013
Sh3betaCG8582 gene product from transcript CG8582-RD0.012
beta'Copbeta'-coatomer protein0.012
Pak3CG14895 gene product from transcript CG14895-RA0.012
Rab2Rab-protein 20.011
MlfMyelodysplasia/myeloid leukemia factor0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.018
Rac1RAS-related C3 botulinum substrate 10.013
Atxn7l3ataxin 7-like 30.012
Arpc4actin related protein 2/3 complex, subunit 40.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.074
Atp6v1b2ATPase, H transporting, lysosomal V1 subunit B20.061
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.053
Tmbim6transmembrane BAX inhibitor motif containing 60.048
Prkar1aprotein kinase, cAMP-dependent, regulatory, type I, alpha0.047
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.031
Rab7aRAB7A, member RAS oncogene family0.027
NsfN-ethylmaleimide-sensitive factor0.021
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.020
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.017
Cttncortactin0.017
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.016
Mapre1microtubule-associated protein, RP/EB family, member 10.014
Chpcalcium binding protein p220.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism