IMP
Process View
The network for 'arf protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
arf protein signal transduction
A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.964 | |
| CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.781 | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.546 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.531 | |
| PXN | paxillin | 0.293 | |
| CTTN | cortactin | 0.134 | |
| COPG | coatomer protein complex, subunit gamma | 0.084 | |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | 0.083 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.077 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.046 | |
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.040 | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.039 | |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.036 | |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.032 | |
| SPRR2A | small proline-rich protein 2A | 0.025 | |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.024 | |
| PDCD6IP | programmed cell death 6 interacting protein | 0.024 | |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.022 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.018 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.018 | |
| CD2AP | CD2-associated protein | 0.017 | |
| ADAM15 | ADAM metallopeptidase domain 15 | 0.017 | |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.016 | |
| WBP11 | WW domain binding protein 11 | 0.015 | |
| CYTH2 | cytohesin 2 | 0.014 | |
| CFL1 | cofilin 1 (non-muscle) | 0.013 | |
| SH3BP2 | SH3-domain binding protein 2 | 0.013 | |
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.013 | |
| SQSTM1 | sequestosome 1 | 0.013 | |
| HMGXB3 | HMG box domain containing 3 | 0.013 | |
| NCK2 | NCK adaptor protein 2 | 0.013 | |
| C4orf14 | chromosome 4 open reading frame 14 | 0.012 | |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.012 | |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.011 |
Loading network...
Drosophila melanogaster| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Arf79F | ADP ribosylation factor 79F | 0.731 | |
| Arc-p34 | CG10954 gene product from transcript CG10954-RA | 0.038 | |
| eff | effete | 0.028 | |
| CG2316 | CG2316 gene product from transcript CG2316-RD | 0.021 | |
| Rab7 | Rab-protein 7 | 0.020 | |
| deltaCOP | delta-coatomer protein | 0.014 | |
| CG6838 | CG6838 gene product from transcript CG6838-RC | 0.014 | |
| ifc | infertile crescent | 0.013 | |
| Cnx99A | Calnexin 99A | 0.013 | |
| Sh3beta | CG8582 gene product from transcript CG8582-RD | 0.012 | |
| beta'Cop | beta'-coatomer protein | 0.012 | |
| Pak3 | CG14895 gene product from transcript CG14895-RA | 0.012 | |
| Rab2 | Rab-protein 2 | 0.011 | |
| Mlf | Myelodysplasia/myeloid leukemia factor | 0.011 |
Loading network...
Rattus norvegicus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.074 | |
| Atp6v1b2 | ATPase, H transporting, lysosomal V1 subunit B2 | 0.061 | |
| Cap1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.053 | |
| Tmbim6 | transmembrane BAX inhibitor motif containing 6 | 0.048 | |
| Prkar1a | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.047 | |
| Cops7a | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) | 0.031 | |
| Rab7a | RAB7A, member RAS oncogene family | 0.027 | |
| Nsf | N-ethylmaleimide-sensitive factor | 0.021 | |
| Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform | 0.020 | |
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.017 | |
| Cttn | cortactin | 0.017 | |
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform | 0.016 | |
| Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.014 | |
| Chp | calcium binding protein p22 | 0.013 |