The network for 'hindlimb morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hindlimb morphogenesis

The process in which the anatomical structures of the hindlimb are generated and organized.

NameDescriptionProbabilityFunc Analog Organism
APCadenomatous polyposis coli0.991
BMP2bone morphogenetic protein 20.942
SETD8SET domain containing (lysine methyltransferase) 80.877
TNRC6Atrinucleotide repeat containing 6A0.831
AFF1AF4/FMR2 family, member 10.746
PDZD11PDZ domain containing 110.661
NOTCH3notch 30.641
JAG1jagged 10.606
ELL2elongation factor, RNA polymerase II, 20.577
GSK3Bglycogen synthase kinase 3 beta0.569
CHD8chromodomain helicase DNA binding protein 80.544
BMPR1Bbone morphogenetic protein receptor, type IB0.502
SMAD2SMAD family member 20.408
LRRK2leucine-rich repeat kinase 20.403
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.377
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.337
EIF2C2eukaryotic translation initiation factor 2C, 20.330
CDK19cyclin-dependent kinase 190.329
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.314
TNRC6Ctrinucleotide repeat containing 6C0.307
DKK1dickkopf homolog 1 (Xenopus laevis)0.305
FGF18fibroblast growth factor 180.300
BMP4bone morphogenetic protein 40.288
TARBP2TAR (HIV-1) RNA binding protein 20.287
JUPjunction plakoglobin0.260
BARX1BARX homeobox 10.250
EIF2C1eukaryotic translation initiation factor 2C, 10.227
FANCCFanconi anemia, complementation group C0.223
MSX2msh homeobox 20.222
MSX1msh homeobox 10.199
ITGB1BP2integrin beta 1 binding protein (melusin) 20.189
EAF1ELL associated factor 10.188
ZFYVE9zinc finger, FYVE domain containing 90.186
AXIN1axin 10.182
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.177
CCNT1cyclin T10.143
CHD4chromodomain helicase DNA binding protein 40.138
PMLpromyelocytic leukemia0.131
MED26mediator complex subunit 260.123
MMP11matrix metallopeptidase 11 (stromelysin 3)0.114
WNT1wingless-type MMTV integration site family, member 10.114
WNT3Awingless-type MMTV integration site family, member 3A0.112
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.103
TCF4transcription factor 40.103
SFRP1secreted frizzled-related protein 10.101
HOXD11homeobox D110.096
NCOR2nuclear receptor corepressor 20.094
SOX2SRY (sex determining region Y)-box 20.093
FSTL1follistatin-like 10.091
FOXF2forkhead box F20.091
FGF3fibroblast growth factor 30.088
FGF8fibroblast growth factor 8 (androgen-induced)0.088
PGAM5phosphoglycerate mutase family member 50.084
HIPK2homeodomain interacting protein kinase 20.083
TAL1T-cell acute lymphocytic leukemia 10.083
WNT11wingless-type MMTV integration site family, member 110.082
DAXXdeath-domain associated protein0.082
XIAPX-linked inhibitor of apoptosis0.081
HOXC8homeobox C80.081
WNT10Awingless-type MMTV integration site family, member 10A0.078
HOXA11homeobox A110.078
HOXD13homeobox D130.077
TBX2T-box 20.074
GLIS2GLIS family zinc finger 20.073
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.071
BTRCbeta-transducin repeat containing0.070
LBX1ladybird homeobox 10.068
BMPR1Abone morphogenetic protein receptor, type IA0.067
WNT4wingless-type MMTV integration site family, member 40.065
RXRAretinoid X receptor, alpha0.065
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.065
GCSHglycine cleavage system protein H (aminomethyl carrier)0.064
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.064
NINninein (GSK3B interacting protein)0.064
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.060
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.058
WIF1WNT inhibitory factor 10.057
DLX5distal-less homeobox 50.057
CRABP2cellular retinoic acid binding protein 20.057
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.055
MAML1mastermind-like 1 (Drosophila)0.055
MTA1metastasis associated 10.055
MDM2Mdm2 p53 binding protein homolog (mouse)0.054
DLL1delta-like 1 (Drosophila)0.054
GATA2GATA binding protein 20.054
HOXB13homeobox B130.053
JAG2jagged 20.053
PAX8paired box 80.052
DVL2dishevelled, dsh homolog 2 (Drosophila)0.052
ELLelongation factor RNA polymerase II0.050
HES2hairy and enhancer of split 2 (Drosophila)0.050
CDX1caudal type homeobox 10.049
FAM101Bfamily with sequence similarity 101, member B0.047
NKX3-2NK3 homeobox 20.047
PGRprogesterone receptor0.047
COL2A1collagen, type II, alpha 10.047
MLLT3myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 30.047
MED10mediator complex subunit 100.047
FOXL1forkhead box L10.046
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Pitx2paired-like homeodomain transcription factor 21.000
Shhsonic hedgehog1.000
Bmp4bone morphogenetic protein 40.999
Tbx3T-box 30.999
Fgf8fibroblast growth factor 80.999
Gli3GLI-Kruppel family member GLI30.999
Foxc1forkhead box C10.998
Hand2heart and neural crest derivatives expressed transcript 20.993
Tgfbr2transforming growth factor, beta receptor II0.992
Otx2orthodenticle homolog 2 (Drosophila)0.992
Ptch1patched homolog 10.992
Pitx1paired-like homeodomain transcription factor 10.989
Pax8paired box gene 80.983
Rargretinoic acid receptor, gamma0.981
Pax2paired box gene 20.979
Msx1homeobox, msh-like 10.978
Smosmoothened homolog (Drosophila)0.974
Pax3paired box gene 30.969
Ptenphosphatase and tensin homolog0.967
Foxc2forkhead box C20.965
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.960
Rararetinoic acid receptor, alpha0.959
Gli2GLI-Kruppel family member GLI20.954
Hand1heart and neural crest derivatives expressed transcript 10.952
Hoxd13homeobox D130.947
Tbx4T-box 40.942
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.937
Hoxa1homeobox A10.937
Ror2receptor tyrosine kinase-like orphan receptor 20.929
Fgf10fibroblast growth factor 100.925
Hoxa10homeobox A100.915
Hoxa13homeobox A130.904
Msx2homeobox, msh-like 20.904
Pax6paired box gene 60.902
Sall4sal-like 4 (Drosophila)0.896
Sox9SRY-box containing gene 90.895
Fgfr1fibroblast growth factor receptor 10.890
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.888
Runx2runt related transcription factor 20.878
Fgf15fibroblast growth factor 150.875
Lhx1LIM homeobox protein 10.872
Ptf1apancreas specific transcription factor, 1a0.844
Tbx1T-box 10.829
Hoxd11homeobox D110.826
Hoxd10homeobox D100.822
Eya1eyes absent 1 homolog (Drosophila)0.818
Pbx1pre B-cell leukemia transcription factor 10.789
Prrx1paired related homeobox 10.759
Sox2SRY-box containing gene 20.750
Hoxa11homeobox A110.748
Gdf5growth differentiation factor 50.739
Tgfb2transforming growth factor, beta 20.712
Bmp7bone morphogenetic protein 70.710
Dlx5distal-less homeobox 50.700
Alx4aristaless-like homeobox 40.692
En1engrailed 10.686
Zic3zinc finger protein of the cerebellum 30.682
Wt1Wilms tumor 1 homolog0.652
Tbx15T-box 150.644
Prrx2paired related homeobox 20.638
Gdf3growth differentiation factor 30.636
Gbx2gastrulation brain homeobox 20.628
Gscgoosecoid homeobox0.621
Ctnnb1catenin (cadherin associated protein), beta 10.595
Otx1orthodenticle homolog 1 (Drosophila)0.595
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.584
Pcsk5proprotein convertase subtilisin/kexin type 50.580
Ascl1achaete-scute complex homolog 1 (Drosophila)0.562
Apcadenomatosis polyposis coli0.533
Dkk1dickkopf homolog 1 (Xenopus laevis)0.526
Fgfr3fibroblast growth factor receptor 30.516
Bmpr1abone morphogenetic protein receptor, type 1A0.507
Rxraretinoid X receptor alpha0.501
Lrp6low density lipoprotein receptor-related protein 60.497
Fgf9fibroblast growth factor 90.486
Alx3aristaless-like homeobox 30.485
Wnt3awingless-related MMTV integration site 3A0.480
Hoxd9homeobox D90.472
Foxh1forkhead box H10.443
Hoxb9homeobox B90.437
Egfrepidermal growth factor receptor0.431
Tcfap2atranscription factor AP-2, alpha0.421
Vangl2vang-like 2 (van gogh, Drosophila)0.397
Lmx1bLIM homeobox transcription factor 1 beta0.394
Pax9paired box gene 90.391
Ptpn11protein tyrosine phosphatase, non-receptor type 110.389
Hoxa2homeobox A20.374
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.374
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.373
Hmx3H6 homeobox 30.365
Jag1jagged 10.361
Emx2empty spiracles homolog 2 (Drosophila)0.353
Foxd3forkhead box D30.338
Wnt5awingless-related MMTV integration site 5A0.331
Gpc3glypican 30.329
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hrasls5HRAS-like suppressor family, member 50.266
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.215
Mmp9matrix metallopeptidase 90.200
Tacr1tachykinin receptor 10.132
Mmp12matrix metallopeptidase 120.132
Ccl4chemokine (C-C motif) ligand 40.121
Il6interleukin 60.121
Egr2early growth response 20.114
Col12a1collagen, type XII, alpha 10.113
Arhgap10Rho GTPase activating protein 100.092
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.086
Cxcl2chemokine (C-X-C motif) ligand 20.085
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.079
Tnftumor necrosis factor (TNF superfamily, member 2)0.075
Psgb1pregnancy-specific beta 1-glycoprotein0.074
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.071
Plauplasminogen activator, urokinase0.071
Accn3amiloride-sensitive cation channel 30.070
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.069
Calcbcalcitonin-related polypeptide, beta0.065
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.061
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.059
Reg3gregenerating islet-derived 3 gamma0.055
Mcpt2mast cell protease 20.055
Il1ainterleukin 1 alpha0.050
Sfrp4secreted frizzled-related protein 40.047
Wnt5awingless-type MMTV integration site family, member 5A0.045
MrgprfMAS-related GPR, member F0.045
Ibspintegrin-binding sialoprotein0.044
Fam38bfamily with sequence similarity 38, member B0.043
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.043
C1qtnf5C1q and tumor necrosis factor related protein 50.042
Prlhrprolactin releasing hormone receptor0.042
Mmp13matrix metallopeptidase 130.041
Fzd2frizzled homolog 2 (Drosophila)0.041
Selpselectin P0.040
Tfectranscription factor EC0.040
Csf3colony stimulating factor 3 (granulocyte)0.040
Mmp7matrix metallopeptidase 70.038
Pipprolactin induced protein0.038
Fosl1fos-like antigen 10.037
Msx1msh homeobox 10.037
Eaf1ELL associated factor 10.037
Dock6dedicator of cytokinesis 60.034
Crisp1cysteine-rich secretory protein 10.034
Col14a1collagen, type XIV, alpha 10.032
Ccl11chemokine (C-C motif) ligand 110.032
Htr2a5-hydroxytryptamine (serotonin) receptor 2A0.032
Gja5gap junction protein, alpha 50.031
Cpa3carboxypeptidase A3, mast cell0.031
Ccl3chemokine (C-C motif) ligand 30.031
Nr2f2nuclear receptor subfamily 2, group F, member 20.031
Foxe3forkhead box E30.031
Mybphmyosin binding protein H0.030
Ptpn14protein tyrosine phosphatase, non-receptor type 140.030
Fbln5fibulin 50.029
P22k15cystatin related protein 20.029
Serpinb12serpin peptidase inhibitor, clade B (ovalbumin), member 120.029
Icosinducible T-cell co-stimulator0.029
Slc16a3solute carrier family 16, member 3 (monocarboxylic acid transporter 4)0.028
Expiextracellular proteinase inhibitor0.028
Prkchprotein kinase C, eta0.027
Slc9a1solute carrier family 9 (sodium/hydrogen exchanger), member 10.027
Ptgesprostaglandin E synthase0.027
Ccna1cyclin A10.026
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.026
Gja4gap junction protein, alpha 40.026
Slc16a8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)0.026
Olfml2bolfactomedin-like 2B0.026
Glycam1glycosylation dependent cell adhesion molecule 10.025
Nraddneurotrophin receptor associated death domain0.025
Lef1lymphoid enhancer binding factor 10.025
Sprr3small proline-rich protein 30.025
Dkk3dickkopf homolog 3 (Xenopus laevis)0.024
Igfbp5insulin-like growth factor binding protein 50.024
Igf2rinsulin-like growth factor 2 receptor0.024
F2rl1coagulation factor II (thrombin) receptor-like 10.024
Plaurplasminogen activator, urokinase receptor0.023
Cgaglycoprotein hormones, alpha polypeptide0.023
Sf3b2splicing factor 3b, subunit 20.023
Aspgasparaginase homolog (S. cerevisiae)0.023
Nfianuclear factor I/A0.023
Ptplad2protein tyrosine phosphatase-like A domain containing 20.022
Ctrcchymotrypsin C (caldecrin)0.022
MosMoloney sarcoma oncogene0.022
LOC683313similar to keratin complex 2, basic, gene 6a0.022
Leprleptin receptor0.022
Meox2mesenchyme homeobox 20.022
Pgfplacental growth factor0.022
Fam69bfamily with sequence similarity 69, member B0.022
Dock8dedicator of cytokinesis 80.021
Bst1bone marrow stromal cell antigen 10.021
Accn5amiloride-sensitive cation channel 5, intestinal0.021
Crispld2cysteine-rich secretory protein LCCL domain containing 20.021
Prrx1paired related homeobox 10.021
Vom2r31vomeronasal 2 receptor, 310.020
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism