The network for 'regulation of rap protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of rap protein signal transduction

Any process that modulates the frequency, rate or extent of Rap protein signal transduction.

NameDescriptionProbabilityFunc Analog Organism
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.884
ABI1abl-interactor 10.722
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.597
RAP1ARAP1A, member of RAS oncogene family0.472
RASSF5Ras association (RalGDS/AF-6) domain family member 50.443
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.394
SOS1son of sevenless homolog 1 (Drosophila)0.391
CLASP1cytoplasmic linker associated protein 10.390
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.367
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.290
DNM2dynamin 20.138
DNM1dynamin 10.132
MAP4K1mitogen-activated protein kinase kinase kinase kinase 10.116
RASSF1Ras association (RalGDS/AF-6) domain family member 10.110
MEOX2mesenchyme homeobox 20.086
ITSN1intersectin 1 (SH3 domain protein)0.076
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.069
LATlinker for activation of T cells0.069
WASLWiskott-Aldrich syndrome-like0.068
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.067
GAB1GRB2-associated binding protein 10.054
GAB2GRB2-associated binding protein 20.051
EPS8epidermal growth factor receptor pathway substrate 80.049
ITSN2intersectin 20.047
STK4serine/threonine kinase 40.047
BCAR1breast cancer anti-estrogen resistance 10.041
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.041
PKN2protein kinase N20.041
RALGDSral guanine nucleotide dissociation stimulator0.040
PTCHD2patched domain containing 20.036
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.035
GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 30.032
ATP8ATP synthase F0 subunit 80.029
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.029
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.026
RHEBRas homolog enriched in brain0.025
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.024
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.024
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.023
BAG1BCL2-associated athanogene0.022
CSNK1G2casein kinase 1, gamma 20.022
MAP2K1mitogen-activated protein kinase kinase 10.022
PIK3AP1phosphoinositide-3-kinase adaptor protein 10.021
LY6G6Flymphocyte antigen 6 complex, locus G6F0.021
ABL2v-abl Abelson murine leukemia viral oncogene homolog 20.021
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.020
PEBP4phosphatidylethanolamine-binding protein 40.020
MAP4K5mitogen-activated protein kinase kinase kinase kinase 50.020
SOS2son of sevenless homolog 2 (Drosophila)0.018
PEBP1phosphatidylethanolamine binding protein 10.017
FGFR1fibroblast growth factor receptor 10.017
NEDD4neural precursor cell expressed, developmentally down-regulated 40.016
PTPRAprotein tyrosine phosphatase, receptor type, A0.016
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.016
SH3PXD2ASH3 and PX domains 2A0.015
BCRbreakpoint cluster region0.015
KRT8keratin 80.014
RHOUras homolog gene family, member U0.013
PLCG1phospholipase C, gamma 10.013
STK3serine/threonine kinase 30.013
SECISBP2LSECIS binding protein 2-like0.013
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.012
RASSF2Ras association (RalGDS/AF-6) domain family member 20.012
BRAFv-raf murine sarcoma viral oncogene homolog B10.012
AP2S1adaptor-related protein complex 2, sigma 1 subunit0.012
REPS2RALBP1 associated Eps domain containing 20.011
CORO1Ccoronin, actin binding protein, 1C0.011
SNAP25synaptosomal-associated protein, 25kDa0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
phlpole hole0.131
PtenCG5671 gene product from transcript CG5671-RB0.094
EphrinCG1862 gene product from transcript CG1862-RA0.045
aopanterior open0.021
Pi3K92ECG4141 gene product from transcript CG4141-RB0.016
Cdc42CG12530 gene product from transcript CG12530-RA0.016
PknProtein kinase related to protein kinase N0.014
RbfRetinoblastoma-family protein0.013
EgfrEpidermal growth factor receptor0.013
RhebCG1081 gene product from transcript CG1081-RA0.012
Stat92ESignal-transducer and activator of transcription protein at 92E0.012
dosdaughter of sevenless0.011
CdsACDP diglyceride synthetase0.011
Src64BSrc oncogene at 64B0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Efnb2ephrin B20.887
Ephb2Eph receptor B20.756
Epha4Eph receptor A40.743
Ephb3Eph receptor B30.224
Efnb1ephrin B10.096
BrafBraf transforming gene0.043
Hprthypoxanthine guanine phosphoribosyl transferase0.040
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.039
Arhgef15Rho guanine nucleotide exchange factor (GEF) 150.036
Trim33tripartite motif-containing 330.036
Raf1v-raf-leukemia viral oncogene 10.030
Kcnk2potassium channel, subfamily K, member 20.025
Cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.021
Nf1neurofibromatosis 10.021
Ptenphosphatase and tensin homolog0.020
Grip1glutamate receptor interacting protein 10.017
Gata5GATA binding protein 50.016
Ptp4a2protein tyrosine phosphatase 4a20.015
Sept7septin 70.013
Tmeff2transmembrane protein with EGF-like and two follistatin-like domains 20.013
Tnks1bp1tankyrase 1 binding protein 10.013
Hif1ahypoxia inducible factor 1, alpha subunit0.012
Plxna2plexin A20.011
Irs1insulin receptor substrate 10.011
Notch1Notch gene homolog 1 (Drosophila)0.011
Sh3rf1SH3 domain containing ring finger 10.010
Grb2growth factor receptor bound protein 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism