The network for 'regulation of cdc42 protein signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cdc42 protein signal transduction

Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.

NameDescriptionProbabilityFunc Analog Organism
TRAF2TNF receptor-associated factor 20.929
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.925
TRAF1TNF receptor-associated factor 10.867
TRADDTNFRSF1A-associated via death domain0.725
APOA1apolipoprotein A-I0.644
TRAF5TNF receptor-associated factor 50.641
TRAF3TNF receptor-associated factor 30.392
SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)0.390
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.280
PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C)0.257
APOC1apolipoprotein C-I0.237
ATP7AATPase, Cu++ transporting, alpha polypeptide0.230
GRB7growth factor receptor-bound protein 70.171
LCATlecithin-cholesterol acyltransferase0.120
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.107
ZNF746zinc finger protein 7460.103
TNFtumor necrosis factor0.098
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.088
ECT2epithelial cell transforming sequence 2 oncogene0.065
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.065
BIRC3baculoviral IAP repeat containing 30.063
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.063
KIF23kinesin family member 230.060
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.058
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.054
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.053
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.041
PVRL2poliovirus receptor-related 2 (herpesvirus entry mediator B)0.040
TNFRSF9tumor necrosis factor receptor superfamily, member 90.033
EPHB3EPH receptor B30.032
SH3KBP1SH3-domain kinase binding protein 10.030
APOC3apolipoprotein C-III0.029
TIFATRAF-interacting protein with forkhead-associated domain0.029
RACGAP1Rac GTPase activating protein 10.028
APOA2apolipoprotein A-II0.025
FAF1Fas (TNFRSF6) associated factor 10.025
SH3BP2SH3-domain binding protein 20.023
CKS2CDC28 protein kinase regulatory subunit 20.022
TNFSF14tumor necrosis factor (ligand) superfamily, member 140.022
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.021
TMSB4Xthymosin beta 4, X-linked0.020
EPHA7EPH receptor A70.019
PLTPphospholipid transfer protein0.019
SH3RF3SH3 domain containing ring finger 30.018
SHC1SHC (Src homology 2 domain containing) transforming protein 10.017
RIPK2receptor-interacting serine-threonine kinase 20.017
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.017
PRKCAprotein kinase C, alpha0.017
CD14CD14 molecule0.017
NCKAP1NCK-associated protein 10.017
BCRbreakpoint cluster region0.016
APOC2apolipoprotein C-II0.016
LRP1low density lipoprotein receptor-related protein 10.015
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.015
APOEapolipoprotein E0.014
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.014
TXNDC2thioredoxin domain containing 2 (spermatozoa)0.014
STX12syntaxin 120.014
FAM118Bfamily with sequence similarity 118, member B0.014
AP2B1adaptor-related protein complex 2, beta 1 subunit0.014
LMO2LIM domain only 2 (rhombotin-like 1)0.014
AP2M1adaptor-related protein complex 2, mu 1 subunit0.013
SEMA3Fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.013
LAD1ladinin 10.013
CD40CD40 molecule, TNF receptor superfamily member 50.013
PVRL3poliovirus receptor-related 30.012
SPRY2sprouty homolog 2 (Drosophila)0.012
TRAF3IP2TRAF3 interacting protein 20.012
APPamyloid beta (A4) precursor protein0.012
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)0.011
LY6G6Flymphocyte antigen 6 complex, locus G6F0.011
HN1hematological and neurological expressed 10.011
IL4Rinterleukin 4 receptor0.011
SYNJ2synaptojanin 20.011
EPHB2EPH receptor B20.011
EPHB6EPH receptor B60.011
FESfeline sarcoma oncogene0.011
PTPN5protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)0.010
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.010
FAM83Cfamily with sequence similarity 83, member C0.010
FGAfibrinogen alpha chain0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
EcREcdysone receptor0.028
Ssb-c31aSingle stranded-binding protein c31A0.027
RanGapRan GTPase activating protein0.025
SmFSmall ribonucleoprotein particle protein SmF0.022
MED22Mediator complex subunit 220.022
Su(var)205Suppressor of variegation 2050.019
Rpb5CG11979 gene product from transcript CG11979-RA0.018
CG5220CG5220 gene product from transcript CG5220-RA0.016
RpII33RNA polymerase II 33kD subunit0.015
phlpole hole0.015
CSN5COP9 complex homolog subunit 50.014
alienCG9556 gene product from transcript CG9556-RB0.014
Aos1CG12276 gene product from transcript CG12276-RA0.013
Rpb11CG6840 gene product from transcript CG6840-RA0.012
Nedd8CG10679 gene product from transcript CG10679-RA0.012
magomago nashi0.012
Nup154Nucleoporin 1540.012
Cbp20cap binding protein 200.012
Prosbeta5Proteasome beta5 subunit0.012
CG11985CG11985 gene product from transcript CG11985-RA0.011
FK506-bp2FK506-binding protein 20.011
EgfrEpidermal growth factor receptor0.010
smt3CG4494 gene product from transcript CG4494-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccl2chemokine (C-C motif) ligand 20.667
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.595
Lyz2lysozyme 20.503
Ifnginterferon gamma0.358
Ccl3chemokine (C-C motif) ligand 30.187
Ccr2chemokine (C-C motif) receptor 20.185
Ccl7chemokine (C-C motif) ligand 70.183
Ccl12chemokine (C-C motif) ligand 120.111
Lrp1low density lipoprotein receptor-related protein 10.107
Tnftumor necrosis factor0.091
Ccr1chemokine (C-C motif) receptor 10.086
Gzmagranzyme A0.083
Ccl8chemokine (C-C motif) ligand 80.077
Abcg1ATP-binding cassette, sub-family G (WHITE), member 10.044
Il1binterleukin 1 beta0.041
Ubdubiquitin D0.039
Il1r1interleukin 1 receptor, type I0.038
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.035
Il1rninterleukin 1 receptor antagonist0.032
Ldlrlow density lipoprotein receptor0.031
C3complement component 30.028
Efnb2ephrin B20.027
Cxcl10chemokine (C-X-C motif) ligand 100.027
Mmp12matrix metallopeptidase 120.026
Npc1Niemann Pick type C10.026
Irg1immunoresponsive gene 10.026
Ccr5chemokine (C-C motif) receptor 50.026
Epha4Eph receptor A40.025
Ch25hcholesterol 25-hydroxylase0.025
Cxcl2chemokine (C-X-C motif) ligand 20.024
Ctnnb1catenin (cadherin associated protein), beta 10.023
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.022
Ltalymphotoxin A0.022
H2-Eb1histocompatibility 2, class II antigen E beta0.021
Ccl4chemokine (C-C motif) ligand 40.020
Clec4dC-type lectin domain family 4, member d0.020
Batfbasic leucine zipper transcription factor, ATF-like0.019
Fcgr2bFc receptor, IgG, low affinity IIb0.019
Icam1intercellular adhesion molecule 10.019
Cxcl1chemokine (C-X-C motif) ligand 10.018
Lag3lymphocyte-activation gene 30.018
FasFas (TNF receptor superfamily member 6)0.018
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.018
Ctswcathepsin W0.016
Socs1suppressor of cytokine signaling 10.016
Ccl22chemokine (C-C motif) ligand 220.016
Il6interleukin 60.016
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.015
Cxcl9chemokine (C-X-C motif) ligand 90.015
Fcgr1Fc receptor, IgG, high affinity I0.014
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.014
BtkBruton agammaglobulinemia tyrosine kinase0.013
Selpselectin, platelet0.013
Batf2basic leucine zipper transcription factor, ATF-like 20.013
Ccl9chemokine (C-C motif) ligand 90.012
Ifngr1interferon gamma receptor 10.012
Cd86CD86 antigen0.011
Cd7CD7 antigen0.011
Cd8aCD8 antigen, alpha chain0.011
Gzmbgranzyme B0.010
Saa3serum amyloid A 30.010
C3ar1complement component 3a receptor 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism