The network for 'myeloid cell homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myeloid cell homeostasis

The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

NameDescriptionProbabilityFunc Analog Organism
SMAD2SMAD family member 20.991
TAL1T-cell acute lymphocytic leukemia 10.989
TP53tumor protein p530.928
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.925
RPS10ribosomal protein S100.820
KAT2BK(lysine) acetyltransferase 2B0.682
SMAD7SMAD family member 70.641
RUNX1runt-related transcription factor 10.629
DDIT3DNA-damage-inducible transcript 30.596
GATA1GATA binding protein 1 (globin transcription factor 1)0.569
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.566
PGK1phosphoglycerate kinase 10.545
SP1Sp1 transcription factor0.528
CASP3caspase 3, apoptosis-related cysteine peptidase0.482
SMAD3SMAD family member 30.479
CREBBPCREB binding protein0.455
NCOA6nuclear receptor coactivator 60.422
XIAPX-linked inhibitor of apoptosis0.410
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.379
PTPN1protein tyrosine phosphatase, non-receptor type 10.368
RPS16ribosomal protein S160.345
S100A10S100 calcium binding protein A100.316
RPS11ribosomal protein S110.314
TCF12transcription factor 120.310
HOXB5homeobox B50.299
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.297
SYKspleen tyrosine kinase0.292
TKTtransketolase0.287
CCND1cyclin D10.280
BCL2L1BCL2-like 10.278
JUNjun proto-oncogene0.273
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.254
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.253
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.246
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.241
UBASH3Bubiquitin associated and SH3 domain containing B0.234
FKBP1AFK506 binding protein 1A, 12kDa0.233
CFLARCASP8 and FADD-like apoptosis regulator0.226
NRP1neuropilin 10.214
HOXA5homeobox A50.212
BCL2B-cell CLL/lymphoma 20.209
ANXA1annexin A10.206
APAF1apoptotic peptidase activating factor 10.203
MSNmoesin0.194
GATA2GATA binding protein 20.178
KHDRBS1KH domain containing, RNA binding, signal transduction associated 10.159
BMPR1Abone morphogenetic protein receptor, type IA0.152
RPS3ribosomal protein S30.142
RPS15Aribosomal protein S15a0.142
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.142
CASP9caspase 9, apoptosis-related cysteine peptidase0.135
SLC4A1solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)0.135
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.133
BMP2bone morphogenetic protein 20.133
EP300E1A binding protein p3000.129
HBG2hemoglobin, gamma G0.129
RPL5ribosomal protein L50.124
GSK3Bglycogen synthase kinase 3 beta0.121
HOXA10homeobox A100.121
GAS6growth arrest-specific 60.117
NCOA1nuclear receptor coactivator 10.114
NCOR2nuclear receptor corepressor 20.111
TGFB1transforming growth factor, beta 10.108
NFE2L2nuclear factor (erythroid-derived 2)-like 20.104
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.104
MAPK8mitogen-activated protein kinase 80.103
NFIL3nuclear factor, interleukin 3 regulated0.102
MDM2Mdm2 p53 binding protein homolog (mouse)0.100
RPS5ribosomal protein S50.099
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.099
PTPN6protein tyrosine phosphatase, non-receptor type 60.099
RPS15ribosomal protein S150.096
BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 10.096
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.095
ARID4BAT rich interactive domain 4B (RBP1-like)0.093
QKIquaking homolog, KH domain RNA binding (mouse)0.092
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.091
BAG3BCL2-associated athanogene 30.090
GATA4GATA binding protein 40.090
APH1Aanterior pharynx defective 1 homolog A (C. elegans)0.089
RBBP4retinoblastoma binding protein 40.085
GAS7growth arrest-specific 70.085
EFTUD2elongation factor Tu GTP binding domain containing 20.084
NMIN-myc (and STAT) interactor0.084
RPS2ribosomal protein S20.081
GYPBglycophorin B (MNS blood group)0.080
SPTBspectrin, beta, erythrocytic0.080
CAPGcapping protein (actin filament), gelsolin-like0.077
SIRT1sirtuin 10.075
RPLP2ribosomal protein, large, P20.074
GHRgrowth hormone receptor0.074
RHAGRh-associated glycoprotein0.072
INSRinsulin receptor0.070
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.068
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.068
SMAD1SMAD family member 10.067
ANK1ankyrin 1, erythrocytic0.067
RPLP1ribosomal protein, large, P10.064
CUX1cut-like homeobox 10.064
HOXA9homeobox A90.062
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
alas2aminolevulinate, delta-, synthetase 20.987
pitx2paired-like homeodomain transcription factor 20.978
epb41erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)0.947
tbx5aT-box 5a0.874
slc4a1asolute carrier family 4, anion exchanger, member 1a0.838
LOC566708FL cytokine receptor-like0.835
hbae3hemoglobin alpha embryonic-30.779
tfr1atransferrin receptor 1a0.726
plcg1phospholipase C, gamma 10.698
isl1islet10.607
tal1T-cell acute lymphocytic leukemia 10.503
gata1aGATA binding protein 1a0.493
klf4Kruppel-like factor 40.457
spns2spinster homolog 2 (Drosophila)0.456
hoxc6ahomeo box C6a0.443
gfi1.1growth factor independent 1.10.432
eporerythropoietin receptor0.389
cpoxcoproporphyrinogen oxidase0.372
pax2apaired box gene 2a0.320
hbbe3hemoglobin beta embryonic-30.307
rpl23aribosomal protein L23a0.300
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.293
gata6GATA-binding protein 60.276
ventventral expressed homeobox0.267
hbbe1.1hemoglobin beta embryonic-1.10.252
myl7myosin, light polypeptide 7, regulatory0.214
mycamyelocytomatosis oncogene a0.212
rxrgaretinoid x receptor, gamma a0.198
dlcdeltaC0.194
gapdhglyceraldehyde-3-phosphate dehydrogenase0.192
ikzf1IKAROS family zinc finger 1 (Ikaros)0.187
hnf1baHNF1 homeobox Ba0.181
uroduroporphyrinogen decarboxylase0.181
mll4bmyeloid/lymphoid or mixed-lineage leukemia 4b0.178
gpiaglucose phosphate isomerase a0.174
si:dkeyp-66d7.2si:dkeyp-66d7.20.159
anxa1bannexin A1b0.156
trim33tripartite motif-containing 330.154
f2rcoagulation factor II (thrombin) receptor0.151
cbfbcore-binding factor, beta subunit0.151
maflv-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L0.147
isl2aislet2a0.145
hey2hairy/enhancer-of-split related with YRPW motif 20.139
bmp2bbone morphogenetic protein 2b0.138
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.130
cahzcarbonic anhydrase0.130
acvr2bactivin receptor IIb0.124
hbaa1hemoglobin alpha adult-10.124
sptbspectrin, beta, erythrocytic0.122
LOC100151531zinc finger protein Gfi-1b-like0.119
spawsouthpaw0.119
prdm1aPR domain containing 1a, with ZNF domain0.114
ca8carbonic anhydrase VIII0.114
rpl11ribosomal protein L110.113
drldraculin0.109
bcl2l1bcl2-like 10.107
gata3GATA-binding protein 30.105
sox7SRY-box containing gene 70.104
jag2jagged 20.104
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.102
si:dkeyp-22b2.3si:dkeyp-22b2.30.099
hdrhematopoietic death receptor0.098
tspotranslocator protein0.096
hoxd4ahomeo box D4a0.096
atoh1aatonal homolog 1a0.095
dlddeltaD0.095
trpv6transient receptor potential cation channel, subfamily V, member 60.094
atoh1batonal homolog 1b0.094
pax3apaired box gene 3a0.091
cebp1CCAAT/enhancer binding protein (C/EBP) 10.091
mpxmyeloid-specific peroxidase0.091
her1hairy-related 10.091
lft2lefty20.087
foxi2forkhead box I20.087
nt5c2l15'-nucleotidase, cytosolic II, like 10.086
ppoxprotoporphyrinogen oxidase0.086
csf3rcolony stimulating factor 3 receptor (granulocyte)0.085
hbbe2hemoglobin beta embryonic-20.084
neurod6bneurogenic differentiation 6b0.083
pycardPYD and CARD domain containing0.082
tfe3btranscription factor binding to IGHM enhancer 3b0.082
mstnbmyostatin b0.081
lhx1aLIM homeobox 1a0.081
eef1b2eukaryotic translation elongation factor 1 beta 20.081
bnip3lbBCL2/adenovirus E1B interacting protein 3-like b0.080
znfl2azinc finger-like gene 2a0.080
zgc:77702zgc:777020.080
aco1aconitase 1, soluble0.079
fauaFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a0.078
pdcd2programmed cell death 20.077
rpl13aribosomal protein L13a0.077
ccnd1cyclin D10.076
zgc:66433zgc:664330.076
gata2aGATA-binding protein 2a0.076
perpPERP, TP53 apoptosis effector0.075
rpl38ribosomal protein L380.074
rps18ribosomal protein S180.074
rps12ribosomal protein S120.074
matr3lmatrin 3-like0.074
ephb4beph receptor B4b0.072
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Spna1spectrin alpha 10.999
Ank1ankyrin 1, erythroid0.997
Slc4a1solute carrier family 4 (anion exchanger), member 10.996
Eporerythropoietin receptor0.994
Hbb-b2hemoglobin, beta adult minor chain0.993
Stat3signal transducer and activator of transcription 30.993
Smad4MAD homolog 4 (Drosophila)0.991
Mapk14mitogen-activated protein kinase 140.991
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.986
Kitkit oncogene0.986
Gata4GATA binding protein 40.971
Pbx1pre B-cell leukemia transcription factor 10.970
Gata1GATA binding protein 10.952
Ikzf1IKAROS family zinc finger 10.948
Smad1MAD homolog 1 (Drosophila)0.934
Tal1T-cell acute lymphocytic leukemia 10.912
Ptenphosphatase and tensin homolog0.898
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.884
Nos3nitric oxide synthase 3, endothelial cell0.883
Trp53transformation related protein 530.877
Gypaglycophorin A0.877
Stat1signal transducer and activator of transcription 10.864
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.849
Lyz2lysozyme 20.848
Wt1Wilms tumor 1 homolog0.834
Ptprcprotein tyrosine phosphatase, receptor type, C0.833
Rxraretinoid X receptor alpha0.828
Hbb-b1hemoglobin, beta adult major chain0.827
Id1inhibitor of DNA binding 10.825
Il6stinterleukin 6 signal transducer0.825
Lcklymphocyte protein tyrosine kinase0.808
Atf2activating transcription factor 20.780
Hoxb3homeobox B30.776
Arid1aAT rich interactive domain 1A (SWI-like)0.774
Bcl2B-cell leukemia/lymphoma 20.766
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.756
Gfi1bgrowth factor independent 1B0.754
Neurod1neurogenic differentiation 10.739
Axin1axin 10.706
Nfe2l2nuclear factor, erythroid derived 2, like 20.694
Meox2mesenchyme homeobox 20.692
Runx1runt related transcription factor 10.687
Tcf4transcription factor 40.684
Smad7MAD homolog 7 (Drosophila)0.684
Hoxa5homeobox A50.673
Ascl1achaete-scute complex homolog 1 (Drosophila)0.665
Irf9interferon regulatory factor 90.664
Shhsonic hedgehog0.659
Il2rginterleukin 2 receptor, gamma chain0.657
Hba-a2hemoglobin alpha, adult chain 20.655
Ctnnb1catenin (cadherin associated protein), beta 10.654
Rbl2retinoblastoma-like 20.653
Hoxb6homeobox B60.635
Sox4SRY-box containing gene 40.625
Fgfr2fibroblast growth factor receptor 20.619
Smad6MAD homolog 6 (Drosophila)0.617
Adam17a disintegrin and metallopeptidase domain 170.602
Notch2Notch gene homolog 2 (Drosophila)0.590
Epas1endothelial PAS domain protein 10.588
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.582
Plac1placental specific protein 10.574
AxlAXL receptor tyrosine kinase0.570
Hoxd1homeobox D10.558
Tgfb2transforming growth factor, beta 20.553
Tgfb1transforming growth factor, beta 10.550
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.537
Hand2heart and neural crest derivatives expressed transcript 20.523
Gpr50G-protein-coupled receptor 500.523
Smad3MAD homolog 3 (Drosophila)0.522
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.519
Tcf3transcription factor 30.510
Trim30atripartite motif-containing 30A0.509
Hoxb8homeobox B80.504
Id3inhibitor of DNA binding 30.499
Vhlvon Hippel-Lindau tumor suppressor0.498
Stat5bsignal transducer and activator of transcription 5B0.486
Hoxb4homeobox B40.469
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.461
CrebbpCREB binding protein0.461
Rspo2R-spondin 2 homolog (Xenopus laevis)0.451
Plcg1phospholipase C, gamma 10.439
Shox2short stature homeobox 20.439
Nfe2nuclear factor, erythroid derived 20.437
Klf1Kruppel-like factor 1 (erythroid)0.435
Egln1EGL nine homolog 1 (C. elegans)0.433
Zfpm2zinc finger protein, multitype 20.433
Prf1perforin 1 (pore forming protein)0.430
Sox10SRY-box containing gene 100.430
Klf3Kruppel-like factor 3 (basic)0.429
Ncoa6nuclear receptor coactivator 60.426
Ptch2patched homolog 20.423
Uba7ubiquitin-like modifier activating enzyme 70.422
Hoxb5homeobox B50.421
Acvrl1activin A receptor, type II-like 10.419
Gja1gap junction protein, alpha 10.415
Neurog1neurogenin 10.413
Socs1suppressor of cytokine signaling 10.410
Spnb2spectrin beta 20.397
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.392
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.390
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hbbhemoglobin, beta0.121
Alas2aminolevulinate, delta-, synthase 20.112
Hba-a2hemoglobin alpha, adult chain 20.100
Elk3ELK3, ETS-domain protein0.096
LOC100134871beta globin minor gene0.092
Ptprcprotein tyrosine phosphatase, receptor type, C0.077
LOC287167globin, alpha0.052
Adam17ADAM metallopeptidase domain 170.045
LOC689064beta-globin0.037
Hbb-b1hemoglobin, beta adult major chain0.028
Jak1Janus kinase 10.016
Tgfbr3transforming growth factor, beta receptor III0.012
Casp3caspase 30.012
Iqgap1IQ motif containing GTPase activating protein 10.012
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism