The network for 'negative regulation of protein metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of protein metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.

NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
TP53tumor protein p531.000
GSK3Bglycogen synthase kinase 3 beta1.000
UBCubiquitin C0.999
RB1retinoblastoma 10.999
PTPN1protein tyrosine phosphatase, non-receptor type 10.999
JUNjun proto-oncogene0.998
EGFRepidermal growth factor receptor0.995
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.994
MAPK1mitogen-activated protein kinase 10.991
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.991
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.989
MAPK14mitogen-activated protein kinase 140.989
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.984
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.984
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.983
PRKCZprotein kinase C, zeta0.981
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.978
DUSP1dual specificity phosphatase 10.978
AKT1v-akt murine thymoma viral oncogene homolog 10.976
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.970
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.969
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.966
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.962
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.958
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.958
XIAPX-linked inhibitor of apoptosis0.951
APPamyloid beta (A4) precursor protein0.950
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.937
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.917
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.913
CREBBPCREB binding protein0.913
HDAC1histone deacetylase 10.912
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.912
SMAD7SMAD family member 70.907
CAV1caveolin 1, caveolae protein, 22kDa0.900
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.899
TNRC6Atrinucleotide repeat containing 6A0.893
HNRNPKheterogeneous nuclear ribonucleoprotein K0.892
MTORmechanistic target of rapamycin (serine/threonine kinase)0.891
ANXA1annexin A10.890
SMAD3SMAD family member 30.888
METmet proto-oncogene (hepatocyte growth factor receptor)0.887
ARRB1arrestin, beta 10.880
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.879
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.879
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.876
PABPC1poly(A) binding protein, cytoplasmic 10.866
GHRgrowth hormone receptor0.862
SMAD4SMAD family member 40.861
ZNF43zinc finger protein 430.849
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.847
MAP3K5mitogen-activated protein kinase kinase kinase 50.846
SIN3ASIN3 homolog A, transcription regulator (yeast)0.825
FASFas (TNF receptor superfamily, member 6)0.824
BCL2L1BCL2-like 10.824
MAP3K7mitogen-activated protein kinase kinase kinase 70.823
RICTORRPTOR independent companion of MTOR, complex 20.823
SHC1SHC (Src homology 2 domain containing) transforming protein 10.822
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.818
BTRCbeta-transducin repeat containing0.817
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.815
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.814
FN1fibronectin 10.814
CUL3cullin 30.810
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.805
PTPN6protein tyrosine phosphatase, non-receptor type 60.800
GABARAPL2GABA(A) receptor-associated protein-like 20.792
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.775
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.774
DAXXdeath-domain associated protein0.756
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.754
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.753
RIPK2receptor-interacting serine-threonine kinase 20.747
CDC37cell division cycle 37 homolog (S. cerevisiae)0.741
RNF11ring finger protein 110.739
PTK2PTK2 protein tyrosine kinase 20.727
IRAK1interleukin-1 receptor-associated kinase 10.727
MAP2K4mitogen-activated protein kinase kinase 40.725
PMLpromyelocytic leukemia0.724
SQSTM1sequestosome 10.722
GRB7growth factor receptor-bound protein 70.722
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.720
SP1Sp1 transcription factor0.718
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.715
LCKlymphocyte-specific protein tyrosine kinase0.709
ZNF273zinc finger protein 2730.703
POU5F1POU class 5 homeobox 10.702
CNOT8CCR4-NOT transcription complex, subunit 80.701
PLCG1phospholipase C, gamma 10.689
RING1ring finger protein 10.686
SORBS3sorbin and SH3 domain containing 30.681
MAPK8mitogen-activated protein kinase 80.680
EPORerythropoietin receptor0.679
HTThuntingtin0.676
SRFserum response factor (c-fos serum response element-binding transcription factor)0.673
SMAD2SMAD family member 20.670
CNOT6CCR4-NOT transcription complex, subunit 60.661
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.658
FOSFBJ murine osteosarcoma viral oncogene homolog0.656
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mec-2Protein MEC-20.109
mex-5Protein MEX-50.099
egl-44Protein EGL-440.059
ntl-2Protein NTL-20.053
eps-8Protein EPS-80.049
F49C12.9Protein F49C12.90.047
sax-3Protein SAX-30.046
imb-2Protein IMB-20.046
ntl-4Protein NTL-40.045
sma-6Protein SMA-60.045
egg-6Protein EGG-60.043
brp-1Protein BRP-10.042
par-5Protein PAR-50.041
tps-1Protein TPS-10.041
let-502Protein LET-5020.037
vab-3Protein VAB-30.037
egl-18Protein EGL-180.036
hlh-30Protein HLH-300.035
ZK507.6Protein ZK507.60.034
lars-1Protein LARS-10.032
csr-1Protein CSR-10.032
spc-1Protein SPC-10.031
pkc-3Protein PKC-30.031
his-45Protein HIS-450.031
his-6Protein HIS-60.030
cbd-1Protein CBD-10.030
ubq-1Protein UBQ-10.030
hpo-32Protein HPO-320.030
F26B1.2Protein F26B1.20.028
mrt-2Protein MRT-20.028
kca-1Protein KCA-10.027
sym-4Protein SYM-40.027
unc-115Protein UNC-1150.026
gld-2Protein GLD-20.026
tba-2Protein TBA-20.025
ajm-1Protein AJM-10.025
daf-21Protein DAF-210.025
nhr-34Protein NHR-340.025
gyg-2Protein GYG-20.025
hum-6Protein HUM-60.025
ztf-17Protein ZTF-170.025
mom-2Protein MOM-20.024
egl-27Protein EGL-270.024
K10D6.4Protein K10D6.40.024
gst-36Protein GST-360.024
his-42Protein HIS-420.024
K07B1.7Protein K07B1.70.023
stau-1Protein STAU-10.023
lpd-7Protein LPD-70.023
zen-4Protein ZEN-40.023
C56G2.5Protein C56G2.50.023
itr-1Protein ITR-10.023
ztf-7Protein ZTF-70.023
F49E8.7Protein F49E8.70.023
rpn-6.1Protein RPN-6.10.023
gly-20Protein GLY-200.022
snr-2Protein SNR-20.022
inx-13Protein INX-130.021
unc-9Protein UNC-90.021
nap-1Protein NAP-10.021
pry-1Protein PRY-10.021
gpd-4Protein GPD-40.021
C37H5.5Protein C37H5.50.021
CELE_C17E4.3Protein C17E4.30.021
rpl-4Protein RPL-40.021
mex-3Protein MEX-30.021
mes-3Protein MES-30.021
mml-1Protein MML-10.020
lmn-1Protein LMN-10.020
rpm-1Protein RPM-10.020
ubr-1Protein UBR-10.020
axl-1Protein AXL-10.020
CELE_R11H6.5Protein R11H6.50.020
sek-1Protein SEK-10.020
alg-1Protein ALG-10.020
cgh-1Protein CGH-10.020
ulp-2Protein ULP-20.019
adr-1Protein ADR-10.019
dgk-2Protein DGK-20.019
akt-2Protein AKT-20.019
puf-5Protein PUF-50.019
CELE_F54D5.5Protein F54D5.50.019
F55A12.5Protein F55A12.50.019
puf-6Protein PUF-60.019
lbp-7Protein LBP-70.018
rnp-5Protein RNP-50.018
T28D9.4Protein T28D9.40.018
CELE_C25A1.4Protein C25A1.40.018
atn-1Protein ATN-10.018
zyg-8Protein ZYG-80.018
egl-15Protein EGL-150.018
F18H3.4Protein F18H3.40.018
F57B9.1Protein F57B9.10.018
dep-1Protein DEP-10.018
egl-8Protein EGL-80.018
riok-1Protein RIOK-10.017
swsn-2.2Protein SWSN-2.20.017
par-1Protein PAR-10.017
unc-43Protein UNC-430.017
tbb-2Protein TBB-20.017
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pcnaproliferating cell nuclear antigen0.270
notch1anotch homolog 1a0.142
sema3aasemaphorin 3aa0.113
frem3Fras1 related extracellular matrix 30.091
egr1early growth response 10.068
bcl2l1bcl2-like 10.060
ccnd1cyclin D10.059
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.056
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.055
brca2breast cancer 2, early onset0.050
cxcr4bchemokine (C-X-C motif), receptor 4b0.050
cx43.4connexin 43.40.046
bmp2bbone morphogenetic protein 2b0.044
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.044
smoc1SPARC related modular calcium binding 10.043
alcamaactivated leukocyte cell adhesion molecule a0.041
usp5ubiquitin specific protease 50.038
ccnb1cyclin B10.037
nclnucleolin0.037
rarabretinoic acid receptor, alpha b0.037
fgfr1afibroblast growth factor receptor 1a0.037
pax8paired box gene 80.037
pou3f1POU class 3 homeobox 10.036
gli1GLI-Kruppel family member 10.034
spry4sprouty (Drosophila) homolog 40.034
caprin1acell cycle associated protein 1a0.032
igf1rainsulin-like growth factor 1a receptor0.032
sall1asal-like 1a (Drosophila)0.032
dab1adisabled homolog 1a (Drosophila)0.030
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.029
pxnpaxillin0.029
ntn2netrin 20.029
ptch2patched 20.029
stc1lstanniocalcin 1, like0.029
meis1myeloid ecotropic viral integration 10.029
zgc:195154zgc:1951540.028
hsp90a.2heat shock protein 90-alpha 20.028
sox11aSRY-box containing gene 11a0.028
dlddeltaD0.027
nf1aneurofibromin 1a0.027
hs6st1aheparan sulfate 6-O-sulfotransferase 1a0.027
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.025
furinafurin (paired basic amino acid cleaving enzyme) a0.025
zgc:56304zgc:563040.025
sulf2lsulfatase 2, like0.025
hnrnpkheterogeneous nuclear ribonucleoprotein K0.024
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.024
rykreceptor-like tyrosine kinase0.024
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.024
bactin2bactin20.024
nrg2aneuregulin 2a0.023
sox11bSRY-box containing gene 11b0.023
u2af2bU2 small nuclear RNA auxiliary factor 2b0.023
ptnpleiotrophin0.023
dusp6dual specificity phosphatase 60.023
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.022
mcl1amyeloid cell leukemia sequence 1a0.022
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.022
mbtps1membrane-bound transcription factor protease, site 10.022
crip2cysteine-rich protein 20.022
shhasonic hedgehog a0.022
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.022
rab11fip4aRAB11 family interacting protein 4 (class II) a0.021
naa50N(alpha)-acetyltransferase 50, NatE catalytic subunit0.021
ptproprotein tyrosine phosphatase, receptor type, O0.021
sox2SRY-box containing gene 20.021
clint1clathrin interactor 10.021
fggfibrinogen, gamma polypeptide0.021
tgfb1atransforming growth factor, beta 1a0.020
bnip3lbBCL2/adenovirus E1B interacting protein 3-like b0.020
ncapgnon-SMC condensin I complex, subunit G0.020
ascl1aachaete-scute complex-like 1a (Drosophila)0.020
srsf1aserine/arginine-rich splicing factor 1a0.020
nog2noggin 20.020
nap1l1nucleosome assembly protein 1, like 10.020
cct8chaperonin containing TCP1, subunit 8 (theta)0.020
rhogbras homolog gene family, member Gb0.020
mbnl2muscleblind-like 2 (Drosophila)0.020
zgc:112211zgc:1122110.020
gmnngeminin, DNA replication inhibitor0.019
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.019
sepw1selenoprotein W, 10.019
col7a1lcollagen type VII alpha 1-like0.019
otpborthopedia homolog b0.019
lhx2bLIM homeobox 2b0.019
cdk8cyclin-dependent kinase 80.018
fabp10afatty acid binding protein 10a, liver basic0.018
evx1even-skipped homeobox 10.018
mapk1mitogen-activated protein kinase 10.018
gpr126G protein-coupled receptor 1260.018
pak2ap21 (CDKN1A)-activated kinase 2a0.018
wnt1wingless-type MMTV integration site family, member 10.018
tnfatumor necrosis factor a (TNF superfamily, member 2)0.018
acvr1lactivin A receptor, type I like0.018
zgc:86759zgc:867590.018
stac3SH3 and cysteine rich domain 30.018
baxabcl2-associated X protein, a0.018
rfngradical fringe homolog (Drosophila)0.017
etv5bets variant 5b0.017
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.017
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
MadMothers against dpp0.559
enaenabled0.504
p53CG33336 gene product from transcript CG33336-RB0.500
EgfrEpidermal growth factor receptor0.438
Ras85DRas oncogene at 85D0.412
oskoskar0.370
drkdownstream of receptor kinase0.330
Pi3K92ECG4141 gene product from transcript CG4141-RB0.322
lokloki0.265
CycBCyclin B0.257
Rho1CG8416 gene product from transcript CG8416-RB0.255
NFATNFAT homolog0.242
poloCG12306 gene product from transcript CG12306-RA0.232
InRInsulin-like receptor0.216
Cdc42CG12530 gene product from transcript CG12530-RA0.211
htshu li tai shao0.202
tshteashirt0.197
G-oalpha47AG protein oalpha 47A0.194
rinrasputin0.169
eghegghead0.168
foxoforkhead box, sub-group O0.161
pucpuckered0.158
chicoCG5686 gene product from transcript CG5686-RB0.158
rlrolled0.146
saxsaxophone0.139
PgkPhosphoglycerate kinase0.134
spispitz0.133
rprreaper0.129
sopstring of pearls0.128
agoarchipelago0.126
Src64BSrc oncogene at 64B0.126
StimStromal interaction molecule0.125
dshdishevelled0.124
par-1CG8201 gene product from transcript CG8201-RA0.123
rapretina aberrant in pattern0.121
auxauxillin0.116
drprdraper0.115
Akt1CG4006 gene product from transcript CG4006-RA0.115
CG5931CG5931 gene product from transcript CG5931-RA0.113
ovoCG6824 gene product from transcript CG6824-RE0.112
CaMKIICalcium/calmodulin-dependent protein kinase II0.111
dncdunce0.109
smt3CG4494 gene product from transcript CG4494-RA0.108
pntpointed0.105
CG1021CG1021 gene product from transcript CG1021-RE0.104
apapterous0.104
ThorCG8846 gene product from transcript CG8846-RA0.104
bskbasket0.103
ImpIGF-II mRNA-binding protein0.103
loqsloquacious0.103
sxcsuper sex combs0.102
CSN5COP9 complex homolog subunit 50.101
krzkurtz0.100
thrthree rows0.100
RanBPMRan-binding protein M0.099
Sema-2aCG4700 gene product from transcript CG4700-RC0.099
encencore0.098
IswiImitation SWI0.097
Socs36ESuppressor of cytokine signaling at 36E0.097
sosine oculis0.096
twinCG31137 gene product from transcript CG31137-RB0.096
trxtrithorax0.094
DoaDarkener of apricot0.092
bambag of marbles0.090
DadDaughters against dpp0.090
wbwing blister0.089
UbxUltrabithorax0.088
Gef26CG9491 gene product from transcript CG9491-RB0.087
hephemipterous0.085
armarmadillo0.084
hipkhomeodomain interacting protein kinase0.084
taitaiman0.084
nwknervous wreck0.082
msnmisshapen0.082
belbelle0.081
cactcactus0.081
sogshort gastrulation0.081
Trim9CG31721 gene product from transcript CG31721-RB0.081
trctricornered0.081
Stat92ESignal-transducer and activator of transcription protein at 92E0.080
SnooSno oncogene0.079
mirrmirror0.078
CG9821CG9821 gene product from transcript CG9821-RB0.077
kaykayak0.077
argosCG4531 gene product from transcript CG4531-RA0.076
SmrSmrter0.076
RpS27ARibosomal protein S27A0.076
mthmethuselah0.075
brmbrahma0.074
RpII215RNA polymerase II 215kD subunit0.073
CG32479CG32479 gene product from transcript CG32479-RA0.073
lgslegless0.073
Sep2Septin-20.073
eyaeyes absent0.073
aretarrest0.073
CG6361CG6361 gene product from transcript CG6361-RA0.073
Cdc37CG12019 gene product from transcript CG12019-RA0.072
SmoxSmad on X0.072
Rac1CG2248 gene product from transcript CG2248-RA0.072
rhorhomboid0.072
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Ptenphosphatase and tensin homolog1.000
Leprleptin receptor0.998
Bcl2B-cell leukemia/lymphoma 20.996
Apcadenomatosis polyposis coli0.990
Stat3signal transducer and activator of transcription 30.986
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.969
Plcg2phospholipase C, gamma 20.960
Appamyloid beta (A4) precursor protein0.945
Rb1retinoblastoma 10.938
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.927
Dusp1dual specificity phosphatase 10.927
Drd2dopamine receptor D20.925
Clockcircadian locomotor output cycles kaput0.924
Ptgs2prostaglandin-endoperoxide synthase 20.920
SkilSKI-like0.911
Socs1suppressor of cytokine signaling 10.909
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.906
Retret proto-oncogene0.904
Emx1empty spiracles homolog 1 (Drosophila)0.898
Egfrepidermal growth factor receptor0.881
FasFas (TNF receptor superfamily member 6)0.881
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.877
Grb2growth factor receptor bound protein 20.868
Per2period homolog 2 (Drosophila)0.867
FosFBJ osteosarcoma oncogene0.862
FynFyn proto-oncogene0.862
Casp4caspase 4, apoptosis-related cysteine peptidase0.854
Tgfb1transforming growth factor, beta 10.851
Axin1axin 10.850
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.839
Nos3nitric oxide synthase 3, endothelial cell0.828
Ptpn11protein tyrosine phosphatase, non-receptor type 110.819
JunJun oncogene0.815
Csf1colony stimulating factor 1 (macrophage)0.814
Smad4MAD homolog 4 (Drosophila)0.811
Tnftumor necrosis factor0.807
Suz12suppressor of zeste 12 homolog (Drosophila)0.807
Smad3MAD homolog 3 (Drosophila)0.805
Foxa2forkhead box A20.803
Zeb1zinc finger E-box binding homeobox 10.801
Rararetinoic acid receptor, alpha0.801
BlnkB-cell linker0.795
Prnpprion protein0.792
Arntlaryl hydrocarbon receptor nuclear translocator-like0.788
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.785
Il6stinterleukin 6 signal transducer0.784
Ctnnb1catenin (cadherin associated protein), beta 10.770
Eif2c2eukaryotic translation initiation factor 2C, 20.768
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.761
Irf8interferon regulatory factor 80.737
Apoeapolipoprotein E0.736
Cry2cryptochrome 2 (photolyase-like)0.732
Nr3c1nuclear receptor subfamily 3, group C, member 10.731
Dvl2dishevelled 2, dsh homolog (Drosophila)0.728
Shhsonic hedgehog0.724
Timp3tissue inhibitor of metalloproteinase 30.724
Apoa1apolipoprotein A-I0.721
Foxp1forkhead box P10.718
Tlr4toll-like receptor 40.710
Irf1interferon regulatory factor 10.707
JunbJun-B oncogene0.702
Icosinducible T-cell co-stimulator0.700
Pax8paired box gene 80.699
Ikzf1IKAROS family zinc finger 10.698
Ptch1patched homolog 10.694
Rxraretinoid X receptor alpha0.693
Nfkbiznuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.693
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.690
Tnfaip3tumor necrosis factor, alpha-induced protein 30.687
Gli2GLI-Kruppel family member GLI20.685
Foxf1aforkhead box F1a0.683
Socs3suppressor of cytokine signaling 30.682
Lhx3LIM homeobox protein 30.681
Hdac1histone deacetylase 10.675
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.669
Otx2orthodenticle homolog 2 (Drosophila)0.668
Spry4sprouty homolog 4 (Drosophila)0.666
Ptprcprotein tyrosine phosphatase, receptor type, C0.663
Mdm4transformed mouse 3T3 cell double minute 40.662
Nf1neurofibromatosis 10.651
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.644
Ascl1achaete-scute complex homolog 1 (Drosophila)0.644
Gdnfglial cell line derived neurotrophic factor0.640
Smad7MAD homolog 7 (Drosophila)0.637
Lyz2lysozyme 20.633
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.631
Onecut1one cut domain, family member 10.630
Thrbthyroid hormone receptor beta0.627
Lef1lymphoid enhancer binding factor 10.622
Insrinsulin receptor0.619
Nos1nitric oxide synthase 1, neuronal0.613
Aim2absent in melanoma 20.612
Cishcytokine inducible SH2-containing protein0.604
Atf2activating transcription factor 20.601
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.599
Rargretinoic acid receptor, gamma0.597
Mndalmyeloid nuclear differentiation antigen like0.596
Vaspvasodilator-stimulated phosphoprotein0.589
Mdm2transformed mouse 3T3 cell double minute 20.588
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Egr1early growth response 10.276
Apohapolipoprotein H (beta-2-glycoprotein I)0.222
Junbjun B proto-oncogene0.199
JunJun oncogene0.191
C9complement component 90.190
Cdk4cyclin-dependent kinase 40.162
Procprotein C0.160
Ptmsparathymosin0.154
Gcgroup specific component0.153
Ahsgalpha-2-HS-glycoprotein0.151
FosFBJ osteosarcoma oncogene0.146
Hspa1aheat shock 70kD protein 1A0.146
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.138
Klf9Kruppel-like factor 90.134
Dnajb1DnaJ (Hsp40) homolog, subfamily B, member 10.131
Hsph1heat shock 105/110 protein 10.130
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.128
Fgafibrinogen alpha chain0.126
Dusp1dual specificity phosphatase 10.123
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.123
Ccnd3cyclin D30.119
Pzppregnancy-zone protein0.117
Tcea2transcription elongation factor A (SII), 20.116
Tdo2tryptophan 2,3-dioxygenase0.114
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.111
Shc1SHC (Src homology 2 domain containing) transforming protein 10.110
Tgoln1trans-golgi network protein0.110
Hphaptoglobin0.102
Ptgs2prostaglandin-endoperoxide synthase 20.102
Klf4Kruppel-like factor 4 (gut)0.099
Thrathyroid hormone receptor alpha0.099
Rhobras homolog gene family, member B0.098
Usf2upstream transcription factor 2, c-fos interacting0.096
Fabp1fatty acid binding protein 1, liver0.095
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.094
Nfianuclear factor I/A0.093
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.092
Aqp9aquaporin 90.092
Itih4inter alpha-trypsin inhibitor, heavy chain 40.091
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.085
Sirpasignal-regulatory protein alpha0.085
Dlg1discs, large homolog 1 (Drosophila)0.085
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.084
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.083
Spp2secreted phosphoprotein 20.083
Selmselenoprotein M0.082
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.081
Calcrlcalcitonin receptor-like0.081
Apoa2apolipoprotein A-II0.080
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.080
Dnaja4DnaJ (Hsp40) homolog, subfamily A, member 40.080
Mx1myxovirus (influenza virus) resistance 10.078
Sgk1serum/glucocorticoid regulated kinase 10.077
Gjb3gap junction protein, beta 30.076
Rbck1RanBP-type and C3HC4-type zinc finger containing 10.076
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.076
Jak2Janus kinase 20.076
Casp2caspase 20.075
Atp6v1fATPase, H transporting, lysosomal V1 subunit F0.074
Myo1bmyosin Ib0.074
Tp53tumor protein p530.073
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.072
Slfn2schlafen 20.072
Pemtphosphatidylethanolamine N-methyltransferase0.072
Tcfe2atranscription factor E2a0.072
C4bpacomplement component 4 binding protein, alpha0.070
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.070
Matkmegakaryocyte-associated tyrosine kinase0.069
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.069
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.069
Errfi1ERBB receptor feedback inhibitor 10.067
NapaN-ethylmaleimide-sensitive factor attachment protein, alpha0.067
Lifleukemia inhibitory factor0.066
Cngb1cyclic nucleotide gated channel beta 10.065
Eif2b5eukaryotic translation initiation factor 2B, subunit 5 epsilon0.065
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.064
Ambpalpha-1-microglobulin/bikunin precursor0.063
Hpxhemopexin0.063
Esr1estrogen receptor 10.063
Ubtfupstream binding transcription factor, RNA polymerase I0.063
Taok1TAO kinase 10.063
Ifitm3interferon induced transmembrane protein 30.063
Cpceruloplasmin0.062
Amhanti-Mullerian hormone0.062
Ppp2cbprotein phosphatase 2, catalytic subunit, beta isoform0.062
Synposynaptopodin0.061
Albalbumin0.061
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.061
Cfdcomplement factor D (adipsin)0.061
Smad1SMAD family member 10.061
Homer1homer homolog 1 (Drosophila)0.060
Sycnsyncollin0.060
Mbl1mannose-binding lectin (protein A) 10.060
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.059
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.059
Pgrprogesterone receptor0.059
Gatad1GATA zinc finger domain containing 10.059
Tgfbr2transforming growth factor, beta receptor II0.059
Ptch1patched homolog 1 (Drosophila)0.058
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.058
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC55Cdc55p0.645
GLC7Glc7p0.477
RTS1Rts1p0.361
MAD2Mad2p0.332
BCK1Bck1p0.304
STI1Sti1p0.304
BRE5Bre5p0.299
DEF1Def1p0.230
BOI1Boi1p0.227
PPH21Pph21p0.219
PSR2Psr2p0.215
CKB1Ckb1p0.209
CDC20Cdc20p0.207
SIS1Sis1p0.192
SLX8Slx8p0.188
SIC1Sic1p0.182
PPH22Pph22p0.155
HTA1Hta1p0.153
SWE1Swe1p0.144
CDC28Cdc28p0.132
DHH1Dhh1p0.127
CTF13Ctf13p0.125
SSA3Ssa3p0.125
NPL3Npl3p0.118
MYO5Myo5p0.117
MAD3Mad3p0.115
SUI3Sui3p0.108
HHF2Hhf2p0.107
GIS1Gis1p0.107
NOP7Nop7p0.101
YME1Yme1p0.098
CDH1Cdh1p0.094
MPT5Mpt5p0.093
CRZ1Crz1p0.091
ROM2Rom2p0.091
STE4Ste4p0.088
DED1Ded1p0.087
SSA1Ssa1p0.087
CAM1Cam1p0.085
YBP2Ybp2p0.084
FAB1Fab1p0.082
RAD23Rad23p0.073
SPT16Spt16p0.073
CDC25Cdc25p0.073
SDS22Sds22p0.072
CSE4Cse4p0.071
STE20Ste20p0.071
EAP1Eap1p0.070
TIP41Tip41p0.069
KEM1Kem1p0.067
NBP2Nbp2p0.067
DCP2Dcp2p0.067
TSR1Tsr1p0.066
WHI2Whi2p0.066
MIF2Mif2p0.066
COX1Cox1p0.065
MDH1Mdh1p0.065
KSP1Ksp1p0.064
KIP1Kip1p0.064
RPS9BRps9bp0.063
DSK2Dsk2p0.063
DCC1Dcc1p0.062
TPD3Tpd3p0.062
PHB1Phb1p0.062
ADR1Adr1p0.062
SOK1Sok1p0.061
FKH1Fkh1p0.061
NGR1Ngr1p0.060
CAK1Cak1p0.060
RLM1Rlm1p0.060
IMP2'Imp2'p0.059
HIR1Hir1p0.058
ARL3Arl3p0.058
SNF1Snf1p0.057
GBP2Gbp2p0.057
NUG1Nug1p0.057
YEL1Yel1p0.056
PRP28Prp28p0.056
DOP1Dop1p0.055
SPT7Spt7p0.055
YHB1Yhb1p0.055
CTK2Ctk2p0.054
MAD1Mad1p0.054
TRS65Trs65p0.054
KIC1Kic1p0.054
IPI1Ipi1p0.053
DRS1Drs1p0.053
CLN2Cln2p0.053
CDC37Cdc37p0.052
ULA1Ula1p0.052
UBR2Ubr2p0.052
YGR054Whypothetical protein0.052
URN1Urn1p0.052
KIN3Kin3p0.052
CLB6Clb6p0.052
CDC15Cdc15p0.052
RRP5Rrp5p0.052
YTA12Yta12p0.051
TDH2Tdh2p0.051
SSE1Sse1p0.050