The network for 'positive regulation of fibroblast migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of fibroblast migration

Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.

NameDescriptionProbabilityFunc Analog Organism
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.991
ENGendoglin0.988
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.985
TGFB1transforming growth factor, beta 10.982
TGFB3transforming growth factor, beta 30.968
THBS1thrombospondin 10.928
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.895
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.875
S100BS100 calcium binding protein B0.847
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.793
COL1A1collagen, type I, alpha 10.769
SHC1SHC (Src homology 2 domain containing) transforming protein 10.703
APPamyloid beta (A4) precursor protein0.626
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.541
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.444
TGFBR1transforming growth factor, beta receptor 10.434
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.415
COL4A1collagen, type IV, alpha 10.412
BGNbiglycan0.397
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.393
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.381
COL11A2collagen, type XI, alpha 20.351
FAPfibroblast activation protein, alpha0.275
BRAFv-raf murine sarcoma viral oncogene homolog B10.269
INHBAinhibin, beta A0.253
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 60.250
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.229
COL1A2collagen, type I, alpha 20.193
FSTL1follistatin-like 10.183
FN1fibronectin 10.172
COL8A1collagen, type VIII, alpha 10.164
DOK1docking protein 1, 62kDa (downstream of tyrosine kinase 1)0.159
SH2D1ASH2 domain containing 1A0.158
COL5A1collagen, type V, alpha 10.135
PCOLCEprocollagen C-endopeptidase enhancer0.133
GPRASP2G protein-coupled receptor associated sorting protein 20.130
TMEM108transmembrane protein 1080.128
TTRtransthyretin0.123
COL6A1collagen, type VI, alpha 10.122
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.119
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.113
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.108
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 20.105
CALD1caldesmon 10.104
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.100
COL6A2collagen, type VI, alpha 20.097
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.077
SH3KBP1SH3-domain kinase binding protein 10.076
IQGAP1IQ motif containing GTPase activating protein 10.075
LOXlysyl oxidase0.075
COL3A1collagen, type III, alpha 10.071
THY1Thy-1 cell surface antigen0.071
COL4A2collagen, type IV, alpha 20.066
TIMP3TIMP metallopeptidase inhibitor 30.065
CTGFconnective tissue growth factor0.062
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.060
FGF2fibroblast growth factor 2 (basic)0.059
RCN3reticulocalbin 3, EF-hand calcium binding domain0.055
TGFB2transforming growth factor, beta 20.054
OSMRoncostatin M receptor0.053
LAMB1laminin, beta 10.053
FILIP1Lfilamin A interacting protein 1-like0.052
AEBP1AE binding protein 10.051
VEGFCvascular endothelial growth factor C0.051
TNCtenascin C0.050
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.048
TNFAIP6tumor necrosis factor, alpha-induced protein 60.047
COL16A1collagen, type XVI, alpha 10.046
PLAUplasminogen activator, urokinase0.044
GREM1gremlin 10.044
CRIPAKcysteine-rich PAK1 inhibitor0.041
MMP14matrix metallopeptidase 14 (membrane-inserted)0.041
COL5A2collagen, type V, alpha 20.040
GRB2growth factor receptor-bound protein 20.040
EDNRAendothelin receptor type A0.039
COL6A3collagen, type VI, alpha 30.038
FBN1fibrillin 10.037
S100A1S100 calcium binding protein A10.036
COL11A1collagen, type XI, alpha 10.036
LRP1low density lipoprotein receptor-related protein 10.036
RHOUras homolog gene family, member U0.035
COL18A1collagen, type XVIII, alpha 10.034
CD84CD84 molecule0.033
FBLN2fibulin 20.033
SULF1sulfatase 10.031
TIMP2TIMP metallopeptidase inhibitor 20.031
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.031
FLNAfilamin A, alpha0.030
LRRK2leucine-rich repeat kinase 20.030
PARVAparvin, alpha0.030
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.030
PRKCAprotein kinase C, alpha0.029
CYR61cysteine-rich, angiogenic inducer, 610.028
PTPN21protein tyrosine phosphatase, non-receptor type 210.028
ACVR2Bactivin A receptor, type IIB0.026
TLN1talin 10.026
HSPG2heparan sulfate proteoglycan 20.025
NTRK1neurotrophic tyrosine kinase, receptor, type 10.025
IGFBP5insulin-like growth factor binding protein 50.025
MXRA5matrix-remodelling associated 50.024
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ldb3LIM domain binding 30.591
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.294
Pxnpaxillin0.260
SrcRous sarcoma oncogene0.188
Prkceprotein kinase C, epsilon0.126
Smad3MAD homolog 3 (Drosophila)0.120
Git1G protein-coupled receptor kinase-interactor 10.083
Mdm2transformed mouse 3T3 cell double minute 20.079
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.076
Lrrk2leucine-rich repeat kinase 20.062
Hspa1bheat shock protein 1B0.034
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.032
Il6stinterleukin 6 signal transducer0.031
Csf1colony stimulating factor 1 (macrophage)0.028
Foxp3forkhead box P30.026
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.025
Hspb8heat shock protein 80.019
Apcadenomatosis polyposis coli0.018
Plcd1phospholipase C, delta 10.017
Vhlvon Hippel-Lindau tumor suppressor0.017
Hspa1aheat shock protein 1A0.016
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.015
Actn2actinin alpha 20.013
Amotl2angiomotin-like 20.011
Rhojras homolog gene family, member J0.011
Mapkapk2MAP kinase-activated protein kinase 20.010
Dnm1dynamin 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism