The network for 'positive regulation of branching involved in ureteric bud morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of branching involved in ureteric bud morphogenesis

Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.

NameDescriptionProbabilityFunc Analog Organism
NRP1neuropilin 10.981
ENGendoglin0.962
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.962
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.714
FSTL1follistatin-like 10.704
PJA1praja ring finger 10.601
MAGED2melanoma antigen family D, 20.452
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.395
PGFplacental growth factor0.171
NKX2-1NK2 homeobox 10.157
TGFBR1transforming growth factor, beta receptor 10.123
TIMP3TIMP metallopeptidase inhibitor 30.117
TGFB3transforming growth factor, beta 30.088
XIAPX-linked inhibitor of apoptosis0.068
BMP7bone morphogenetic protein 70.054
BMP2bone morphogenetic protein 20.054
THBS1thrombospondin 10.048
DNAJC1DnaJ (Hsp40) homolog, subfamily C, member 10.047
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.047
MDFIMyoD family inhibitor0.044
CD2BP2CD2 (cytoplasmic tail) binding protein 20.041
PTPRBprotein tyrosine phosphatase, receptor type, B0.038
C5orf13chromosome 5 open reading frame 130.034
NOTCH1notch 10.034
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.033
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.033
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.031
ZFYVE9zinc finger, FYVE domain containing 90.028
BBS1Bardet-Biedl syndrome 10.027
HOXB5homeobox B50.027
SMAD7SMAD family member 70.024
HOXB6homeobox B60.022
HOXA11homeobox A110.021
TGFBR3transforming growth factor, beta receptor III0.021
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.021
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.020
SERPINA5serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 50.020
SSR1signal sequence receptor, alpha0.020
DDIT4DNA-damage-inducible transcript 40.020
WNT7Awingless-type MMTV integration site family, member 7A0.019
PDK1pyruvate dehydrogenase kinase, isozyme 10.019
HNF1AHNF1 homeobox A0.018
NDNL2necdin-like 20.018
EYA2eyes absent homolog 2 (Drosophila)0.018
BHLHE40basic helix-loop-helix family, member e400.017
HOXB9homeobox B90.017
ADH1Balcohol dehydrogenase 1B (class I), beta polypeptide0.017
COL2A1collagen, type II, alpha 10.017
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.016
FGF8fibroblast growth factor 8 (androgen-induced)0.016
CASP9caspase 9, apoptosis-related cysteine peptidase0.016
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.016
TGFB2transforming growth factor, beta 20.016
COPG2coatomer protein complex, subunit gamma 20.015
AKNAAT-hook transcription factor0.015
EFNA1ephrin-A10.015
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.015
EYA1eyes absent homolog 1 (Drosophila)0.015
SHC2SHC (Src homology 2 domain containing) transforming protein 20.014
ARRB1arrestin, beta 10.014
SIM2single-minded homolog 2 (Drosophila)0.014
LHX1LIM homeobox 10.014
CASP7caspase 7, apoptosis-related cysteine peptidase0.014
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.014
WT1Wilms tumor 10.014
PAX7paired box 70.013
LDLRlow density lipoprotein receptor0.013
CASP3caspase 3, apoptosis-related cysteine peptidase0.013
NR5A1nuclear receptor subfamily 5, group A, member 10.013
PAEPprogestagen-associated endometrial protein0.013
INHBBinhibin, beta B0.013
SHBSrc homology 2 domain containing adaptor protein B0.013
FOXA2forkhead box A20.013
BBS4Bardet-Biedl syndrome 40.013
TBCDtubulin folding cofactor D0.013
CD14CD14 molecule0.013
COPGcoatomer protein complex, subunit gamma0.012
CDH5cadherin 5, type 2 (vascular endothelium)0.012
CDH6cadherin 6, type 2, K-cadherin (fetal kidney)0.012
VTNvitronectin0.012
EPAS1endothelial PAS domain protein 10.012
STC2stanniocalcin 20.011
TERF2IPtelomeric repeat binding factor 2, interacting protein0.011
NDRG1N-myc downstream regulated 10.011
USF1upstream transcription factor 10.011
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.011
SLC6A8solute carrier family 6 (neurotransmitter transporter, creatine), member 80.011
GFRA3GDNF family receptor alpha 30.011
HNF1BHNF1 homeobox B0.011
EDEM1ER degradation enhancer, mannosidase alpha-like 10.011
FOXF1forkhead box F10.011
ILVBLilvB (bacterial acetolactate synthase)-like0.010
PTPRJprotein tyrosine phosphatase, receptor type, J0.010
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.010
CLUclusterin0.010
LAMC3laminin, gamma 30.010
PSMF1proteasome (prosome, macropain) inhibitor subunit 1 (PI31)0.010
MYOD1myogenic differentiation 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pax2paired box gene 21.000
Fgf8fibroblast growth factor 81.000
Gli3GLI-Kruppel family member GLI31.000
Rargretinoic acid receptor, gamma1.000
Fgfr2fibroblast growth factor receptor 21.000
Pax3paired box gene 31.000
Foxc2forkhead box C21.000
Foxc1forkhead box C10.999
Pitx2paired-like homeodomain transcription factor 20.999
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.999
Smosmoothened homolog (Drosophila)0.999
Tcfap2atranscription factor AP-2, alpha0.999
Otx2orthodenticle homolog 2 (Drosophila)0.999
Eya1eyes absent 1 homolog (Drosophila)0.998
Emx2empty spiracles homolog 2 (Drosophila)0.997
Lhx1LIM homeobox protein 10.996
Fgf10fibroblast growth factor 100.996
Hoxa3homeobox A30.996
Fgfr1fibroblast growth factor receptor 10.995
Pax8paired box gene 80.994
Pax6paired box gene 60.992
Sox2SRY-box containing gene 20.992
Sall4sal-like 4 (Drosophila)0.990
Msx1homeobox, msh-like 10.989
Gli2GLI-Kruppel family member GLI20.987
Nognoggin0.984
Gbx2gastrulation brain homeobox 20.978
Hoxa1homeobox A10.978
Wt1Wilms tumor 1 homolog0.978
Hand1heart and neural crest derivatives expressed transcript 10.974
Rarbretinoic acid receptor, beta0.969
Msx2homeobox, msh-like 20.966
Tbx1T-box 10.965
Sox9SRY-box containing gene 90.965
Bmp4bone morphogenetic protein 40.964
Hoxb3homeobox B30.948
Hoxd3homeobox D30.937
Hoxd11homeobox D110.935
Ror2receptor tyrosine kinase-like orphan receptor 20.930
Nos3nitric oxide synthase 3, endothelial cell0.928
Otx1orthodenticle homolog 1 (Drosophila)0.923
Prrx1paired related homeobox 10.918
Hoxc5homeobox C50.909
Bmp7bone morphogenetic protein 70.908
Isl1ISL1 transcription factor, LIM/homeodomain0.903
En1engrailed 10.890
Dlx5distal-less homeobox 50.889
Hoxa2homeobox A20.888
Hoxa10homeobox A100.887
Hand2heart and neural crest derivatives expressed transcript 20.886
Hoxa5homeobox A50.883
Rararetinoic acid receptor, alpha0.877
Hoxd9homeobox D90.872
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.870
Dkk1dickkopf homolog 1 (Xenopus laevis)0.856
Hoxb6homeobox B60.848
Wnt4wingless-related MMTV integration site 40.848
Retret proto-oncogene0.845
Fgf3fibroblast growth factor 30.842
Prrx2paired related homeobox 20.830
Nr5a1nuclear receptor subfamily 5, group A, member 10.828
Wnt3awingless-related MMTV integration site 3A0.803
Hoxd4homeobox D40.796
Hoxa11homeobox A110.776
Pou3f3POU domain, class 3, transcription factor 30.762
Gdnfglial cell line derived neurotrophic factor0.756
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.749
Tgfb2transforming growth factor, beta 20.732
Emx1empty spiracles homolog 1 (Drosophila)0.718
Hoxc8homeobox C80.670
Tbx2T-box 20.667
Hoxd13homeobox D130.624
Ednraendothelin receptor type A0.610
Lmx1bLIM homeobox transcription factor 1 beta0.595
Tbrachyury0.583
Twist2twist homolog 2 (Drosophila)0.582
Sox11SRY-box containing gene 110.575
Hes5hairy and enhancer of split 5 (Drosophila)0.565
Hoxb5homeobox B50.550
Chrdchordin0.539
Foxg1forkhead box G10.527
Lef1lymphoid enhancer binding factor 10.514
Meox2mesenchyme homeobox 20.513
Agtr1aangiotensin II receptor, type 1a0.502
Lhx3LIM homeobox protein 30.495
Tbx3T-box 30.494
Hoxc4homeobox C40.485
Foxf2forkhead box F20.476
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.471
Nodalnodal0.468
Pbx1pre B-cell leukemia transcription factor 10.466
Vegfavascular endothelial growth factor A0.455
Tcfap2ctranscription factor AP-2, gamma0.455
Sox7SRY-box containing gene 70.450
Arandrogen receptor0.445
Bnc1basonuclin 10.416
Hoxb4homeobox B40.415
Hoxc9homeobox C90.414
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.402
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism