The network for 'maintenance of protein location' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

maintenance of protein location

Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.

NameDescriptionProbabilityFunc Analog Organism
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.914
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.912
SMAD2SMAD family member 20.875
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.836
GSK3Bglycogen synthase kinase 3 beta0.778
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.775
CKAP5cytoskeleton associated protein 50.764
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.709
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.664
PKD2polycystic kidney disease 2 (autosomal dominant)0.603
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.597
CENPEcentromere protein E, 312kDa0.580
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.562
KIF23kinesin family member 230.555
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.553
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.538
SYNE1spectrin repeat containing, nuclear envelope 10.534
RACGAP1Rac GTPase activating protein 10.499
SMAD4SMAD family member 40.478
NUF2NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.437
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.377
SUN1Sad1 and UNC84 domain containing 10.372
RBL1retinoblastoma-like 1 (p107)0.370
PRC1protein regulator of cytokinesis 10.343
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.339
RHOAras homolog gene family, member A0.334
ZWINTZW10 interactor0.329
CDC25Bcell division cycle 25 homolog B (S. pombe)0.326
ENGendoglin0.318
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.310
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.309
CKS2CDC28 protein kinase regulatory subunit 20.305
PLK1polo-like kinase 10.289
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.273
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.254
CREBBPCREB binding protein0.251
BMP2bone morphogenetic protein 20.248
ZMYND11zinc finger, MYND-type containing 110.230
SFNstratifin0.227
FN1fibronectin 10.216
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.212
DLGAP5discs, large (Drosophila) homolog-associated protein 50.207
TAF5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa0.206
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.196
CEP55centrosomal protein 55kDa0.194
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.193
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.191
ANLNanillin, actin binding protein0.190
MSNmoesin0.182
FKBP1AFK506 binding protein 1A, 12kDa0.181
ZNF84zinc finger protein 840.178
GGA2golgi-associated, gamma adaptin ear containing, ARF binding protein 20.170
CSNK1A1casein kinase 1, alpha 10.167
SUN2Sad1 and UNC84 domain containing 20.164
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.159
MIS12MIS12, MIND kinetochore complex component, homolog (S. pombe)0.159
APCadenomatous polyposis coli0.156
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.154
SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)0.142
CBX5chromobox homolog 50.141
ECT2epithelial cell transforming sequence 2 oncogene0.139
FLNAfilamin A, alpha0.138
HIPK3homeodomain interacting protein kinase 30.137
FLNBfilamin B, beta0.136
ACTN1actinin, alpha 10.136
SYNE2spectrin repeat containing, nuclear envelope 20.135
PKD1polycystic kidney disease 1 (autosomal dominant)0.129
SPC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.128
YAP1Yes-associated protein 10.124
DMDdystrophin0.121
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.118
TLN1talin 10.115
NUP85nucleoporin 85kDa0.114
ERBB2IPerbb2 interacting protein0.112
CASC5cancer susceptibility candidate 50.111
ZFYVE9zinc finger, FYVE domain containing 90.110
PEX19peroxisomal biogenesis factor 190.109
MYH9myosin, heavy chain 9, non-muscle0.106
TBCDtubulin folding cofactor D0.105
VCANversican0.105
IQGAP1IQ motif containing GTPase activating protein 10.104
PSEN1presenilin 10.104
CDK1cyclin-dependent kinase 10.103
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.101
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.096
IGF2Rinsulin-like growth factor 2 receptor0.094
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.092
SPC24SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.091
KIF14kinesin family member 140.090
CDC25Acell division cycle 25 homolog A (S. pombe)0.088
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.087
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.086
PEX5peroxisomal biogenesis factor 50.086
MARCH7membrane-associated ring finger (C3HC4) 70.086
MDM4Mdm4 p53 binding protein homolog (mouse)0.084
BBS4Bardet-Biedl syndrome 40.084
KIF18Akinesin family member 18A0.083
SMURF2SMAD specific E3 ubiquitin protein ligase 20.082
ZNF585Azinc finger protein 585A0.081
PCM1pericentriolar material 10.080
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.369
cup-2Protein CUP-20.283
hsp-1Protein HSP-10.270
spdl-1Protein SPDL-10.256
tam-1Protein TAM-10.233
ubxn-4Protein UBXN-40.195
hcp-2Protein HCP-20.190
tba-2Protein TBA-20.181
pha-4Protein PHA-40.179
mcm-7Protein MCM-70.165
klp-19Protein KLP-190.157
hmg-1.2Protein HMG-1.20.148
elt-6Protein ELT-60.131
mcm-2Protein MCM-20.130
cnd-1Protein CND-10.115
hcp-4Protein HCP-40.115
rod-1Protein ROD-10.115
T19H12.2Protein T19H12.20.110
rab-1Protein RAB-10.108
atl-1Protein ATL-10.101
eff-1Protein EFF-10.090
unc-70Protein UNC-700.090
knl-1Protein KNL-10.084
bmk-1Protein BMK-10.082
stam-1Protein STAM-10.075
tbb-2Protein TBB-20.074
zfp-1Protein ZFP-10.073
chc-1Protein CHC-10.068
rbc-1Protein RBC-10.067
pdi-3Protein PDI-30.066
spk-1Protein SPK-10.065
F39G3.3Protein F39G3.30.065
cls-2Protein CLS-20.062
dcr-1Protein DCR-10.060
let-2Protein LET-20.059
rpn-1Protein RPN-10.058
ztf-7Protein ZTF-70.057
emb-30Protein EMB-300.055
F33H2.5Protein F33H2.50.053
him-10Protein HIM-100.052
T09B9.4Protein T09B9.40.050
gpr-1Protein GPR-10.050
cyb-2.2Protein CYB-2.20.049
flh-1Protein FLH-10.049
icp-1Protein ICP-10.047
set-16Protein SET-160.046
lin-13Protein LIN-130.046
air-2Protein AIR-20.046
fzy-1Protein FZY-10.046
acs-4Protein ACS-40.045
aspm-1Protein ASPM-10.045
T07C4.10Protein T07C4.100.044
hlh-1Protein HLH-10.044
bub-1Protein BUB-10.044
sago-1Protein SAGO-10.044
knl-2Protein KNL-20.044
zyg-9Protein ZYG-90.043
dsh-2Protein DSH-20.041
rgs-7Protein RGS-70.040
mep-1Protein MEP-10.040
math-33Protein MATH-330.040
prp-8Protein PRP-80.039
lap-2Protein LAP-20.039
eef-1A.1Protein EEF-1A.10.037
ZC434.8Protein ZC434.80.037
hnd-1Protein HND-10.037
mcm-6Protein MCM-60.035
unc-83Protein UNC-830.035
spd-2Protein SPD-20.035
pop-1Protein POP-10.034
pcn-1Protein PCN-10.034
alg-2Protein ALG-20.034
CELE_R06A4.2Protein R06A4.20.033
chd-7Protein CHD-70.033
hcp-1Protein HCP-10.033
tbb-1Protein TBB-10.032
smc-3Protein SMC-30.031
ZK507.6Protein ZK507.60.030
ugt-23Protein UGT-230.029
sar-1Protein SAR-10.029
ten-1Protein TEN-10.028
pry-1Protein PRY-10.028
R05D3.2Protein R05D3.20.027
uaf-1Protein UAF-10.027
F52G3.1Protein F52G3.10.026
F33H2.3Protein F33H2.30.026
F56D2.6Protein F56D2.60.026
ttm-4Protein TTM-40.026
cyb-1Protein CYB-10.026
lin-12Protein LIN-120.025
K10C8.3Protein K10C8.30.025
tag-353Protein TAG-3530.025
clic-1Protein CLIC-10.025
pod-1Protein POD-10.025
R11A8.7Protein R11A8.70.025
imp-2Protein IMP-20.025
lin-33Protein LIN-330.025
H11E01.3Protein H11E01.30.025
gei-8Protein GEI-80.024
shc-2Protein SHC-20.024
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
MybMyb oncogene-like0.750
aopanterior open0.707
cnocanoe0.591
chicchickadee0.579
ctpcut up0.492
zipzipper0.490
rokRho-kinase0.483
ChcClathrin heavy chain0.467
fufused0.461
Cdc42CG12530 gene product from transcript CG12530-RA0.335
mysmyospheroid0.299
eglegalitarian0.283
enaenabled0.279
MerMerlin0.239
cmetCENP-meta0.232
sqhspaghetti squash0.221
emcextra macrochaetae0.220
flwflapwing0.205
cicubitus interruptus0.177
pimpimples0.166
Rab5Rab-protein 50.154
fogfolded gastrulation0.142
ana3anastral spindle 30.131
Pp2A-29BProtein phosphatase 2A at 29B0.130
tumtumbleweed0.126
Sas-4CG10061 gene product from transcript CG10061-RA0.124
auxauxillin0.123
StimStromal interaction molecule0.121
uspultraspiracle0.121
p120ctnAdherens junction protein p1200.121
shgshotgun0.115
mewmultiple edematous wings0.112
trctricornered0.110
AblAbl tyrosine kinase0.101
Cul-2Cullin-20.094
mit(1)15mitotic 150.093
gishgilgamesh0.093
msnmisshapen0.087
pavpavarotti0.086
Poc1Proteome of centrioles 10.083
aspabnormal spindle0.080
Sep2Septin-20.079
dshdishevelled0.076
RYBPRing and YY1 Binding Protein0.075
armarmadillo0.074
Cenp-CCG31258 gene product from transcript CG31258-RA0.073
sleslender lobes0.073
CycACyclin A0.069
bifbifocal0.067
JraJun-related antigen0.067
CG7830CG7830 gene product from transcript CG7830-RA0.066
alphaTub67Calpha-Tubulin at 67C0.063
Dsor1Downstream of raf10.063
ncdnon-claret disjunctional0.061
PvrPDGF- and VEGF-receptor related0.058
klarklarsicht0.058
trioCG18214 gene product from transcript CG18214-RA0.057
putpunt0.057
AlyCG1101 gene product from transcript CG1101-RA0.055
stgstring0.055
Rho1CG8416 gene product from transcript CG8416-RB0.054
Rab11Rab-protein 110.052
CG1943CG1943 gene product from transcript CG1943-RA0.052
Klp10ACG1453 gene product from transcript CG1453-RA0.050
twstwins0.049
Eb1CG3265 gene product from transcript CG3265-RF0.049
Taf8TBP-associated factor 80.048
bazbazooka0.048
ttvtout-velu0.047
G-ialpha65AG protein alphai subunit 65A0.046
mbcmyoblast city0.045
aslasterless0.044
fzyfizzy0.044
marsCG17064 gene product from transcript CG17064-RB0.044
armiarmitage0.043
Src42ASrc oncogene at 42A0.043
AbiAbelson interacting protein0.042
ph-ppolyhomeotic proximal0.041
RhebCG1081 gene product from transcript CG1081-RA0.040
CycBCyclin B0.040
GugGrunge0.039
Cks30ACyclin-dependent kinase subunit 30A0.039
Tip60CG6121 gene product from transcript CG6121-RA0.038
PRL-1CG4993 gene product from transcript CG4993-RB0.038
Ras85DRas oncogene at 85D0.037
Cp110CG14617 gene product from transcript CG14617-RB0.037
lqfliquid facets0.035
sggshaggy0.035
Vap-33-1CG5014 gene product from transcript CG5014-RB0.035
CycB3Cyclin B30.033
CG9053CG9053 gene product from transcript CG9053-RA0.032
lkb1CG9374 gene product from transcript CG9374-RJ0.032
wispwispy0.032
diadiaphanous0.031
ensensconsin0.031
l(2)gllethal (2) giant larvae0.030
SosSon of sevenless0.030
Dhc64CDynein heavy chain 64C0.029
Arp14DActin-related protein 14D0.029
cnkconnector enhancer of ksr0.029
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pdia3protein disulfide isomerase family A, member 30.112
LOC100362824caveolin 2-like0.109
Strnstriatin, calmodulin binding protein0.052
Pdia6protein disulfide isomerase family A, member 60.050
Cav2caveolin 20.049
Traf4af1TRAF4 associated factor 10.032
Cav1caveolin 1, caveolae protein0.030
Arf1ADP-ribosylation factor 10.026
Hsp90b1heat shock protein 90, beta, member 10.022
Manfmesencephalic astrocyte-derived neurotrophic factor0.021
Arl1ADP-ribosylation factor-like 10.013
Pttg1pituitary tumor-transforming 10.012
Kif22kinesin family member 220.012
Lrrc59leucine rich repeat containing 590.012
St3gal2ST3 beta-galactoside alpha-2,3-sialyltransferase 20.012
Ube2cubiquitin-conjugating enzyme E2C0.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
DAD2Dad2p0.884
SPC34Spc34p0.876
ASK1Ask1p0.857
DUO1Duo1p0.757
DAD4Dad4p0.755
ERP5Erp5p0.537
DAM1Dam1p0.513
SPC19Spc19p0.431
DAD1Dad1p0.417
HSK3Hsk3p0.405
VPS17Vps17p0.297
CKS1Cks1p0.225
CLB6Clb6p0.217
VPS5Vps5p0.204
DAD3Dad3p0.187
NKP2Nkp2p0.172
SPC29Spc29p0.170
CAP1Cap1p0.166
RER1Rer1p0.157
VIK1Vik1p0.157
CDC28Cdc28p0.154
OST2Ost2p0.151
SWE1Swe1p0.144
RHO1Rho1p0.143
CHL4Chl4p0.121
VPS35Vps35p0.120
IST1Ist1p0.118
DSN1Dsn1p0.118
IML3Iml3p0.117
TID3Tid3p0.113
VPS29Vps29p0.110
MIF2Mif2p0.107
SHE1She1p0.107
KIP1Kip1p0.105
VPS34Vps34p0.098
CSE4Cse4p0.094
FIN1Fin1p0.094
VPS38Vps38p0.091
CDC20Cdc20p0.091
BMH1Bmh1p0.087
MCM21Mcm21p0.087
RNR2Rnr2p0.085
TED1Ted1p0.084
MTW1Mtw1p0.082
AIM7Aim7p0.079
ERP2Erp2p0.078
NNF1Nnf1p0.077
COQ5Coq5p0.076
NDD1Ndd1p0.075
VAC8Vac8p0.074
BUB3Bub3p0.073
CLB4Clb4p0.073
CIN8Cin8p0.070
PEP1Pep1p0.069
NBL1Nbl1p0.069
GAL10Gal10p0.067
CSF1Csf1p0.065
VPS74Vps74p0.065
YPI1Ypi1p0.064
GAL80Gal80p0.064
RPN14Rpn14p0.063
SBA1Sba1p0.063
CLN1Cln1p0.063
NAB3Nab3p0.063
HOC1Hoc1p0.063
CIN2Cin2p0.062
EMP24Emp24p0.062
VPS25Vps25p0.062
SCJ1Scj1p0.061
OKP1Okp1p0.059
CDC48Cdc48p0.059
VTA1Vta1p0.059
HDA2Hda2p0.059
YPL014Whypothetical protein0.058
SAK1Sak1p0.057
SPC97Spc97p0.056
PIN4Pin4p0.055
CLB2Clb2p0.055
SAC7Sac7p0.055
CLB5Clb5p0.054
APL6Apl6p0.054
MDM20Mdm20p0.054
KAR9Kar9p0.053
VPS28Vps28p0.053
KAR3Kar3p0.053
YBR096Whypothetical protein0.050
IQG1Iqg1p0.050
SHP1Shp1p0.049
TLG2Tlg2p0.049
EXO84Exo84p0.048
GBP2Gbp2p0.048
MVP1Mvp1p0.048
ILM1Ilm1p0.048
RHO5Rho5p0.048
APE3Ape3p0.047
KIN2Kin2p0.047
YCK1Yck1p0.047
AMN1Amn1p0.047
NUF2Nuf2p0.046
YMR1Ymr1p0.046