The network for 'gastrulation with mouth forming second' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gastrulation with mouth forming second

A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.

NameDescriptionProbabilityFunc Analog Organism
CTNND1catenin (cadherin-associated protein), delta 10.849
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.741
HCFC1host cell factor C1 (VP16-accessory protein)0.445
DSG2desmoglein 20.387
AMOTL1angiomotin like 10.309
BMI1BMI1 polycomb ring finger oncogene0.301
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.294
FGFR1fibroblast growth factor receptor 10.291
YAP1Yes-associated protein 10.246
SMAD2SMAD family member 20.238
LMO4LIM domain only 40.231
PSEN1presenilin 10.204
BMP1bone morphogenetic protein 10.199
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.193
MKL1megakaryoblastic leukemia (translocation) 10.187
SMAD3SMAD family member 30.173
HSF1heat shock transcription factor 10.144
JUNjun proto-oncogene0.125
CDH3cadherin 3, type 1, P-cadherin (placental)0.118
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.115
ZFYVE9zinc finger, FYVE domain containing 90.110
CAPRIN2caprin family member 20.110
PCGF5polycomb group ring finger 50.104
ARandrogen receptor0.103
SMAD1SMAD family member 10.096
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.091
DEDDdeath effector domain containing0.087
PHC2polyhomeotic homolog 2 (Drosophila)0.086
TGFBR1transforming growth factor, beta receptor 10.086
GSK3Bglycogen synthase kinase 3 beta0.075
PTPRJprotein tyrosine phosphatase, receptor type, J0.071
MKL2MKL/myocardin-like 20.070
JUPjunction plakoglobin0.067
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.064
ZHX1zinc fingers and homeoboxes 10.060
PTPN11protein tyrosine phosphatase, non-receptor type 110.056
CHMP7CHMP family, member 70.056
TP63tumor protein p630.054
AKT1v-akt murine thymoma viral oncogene homolog 10.053
CXXC5CXXC finger protein 50.052
CBX8chromobox homolog 80.051
ATF7IPactivating transcription factor 7 interacting protein0.050
LRRK2leucine-rich repeat kinase 20.049
PKP4plakophilin 40.048
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.047
KLF13Kruppel-like factor 130.045
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.043
EGFRepidermal growth factor receptor0.043
FZD1frizzled homolog 1 (Drosophila)0.043
TWIST2twist homolog 2 (Drosophila)0.042
SMURF1SMAD specific E3 ubiquitin protein ligase 10.041
WNT3Awingless-type MMTV integration site family, member 3A0.041
SKILSKI-like oncogene0.041
EFTUD2elongation factor Tu GTP binding domain containing 20.041
FERMT2fermitin family member 20.040
PCGF1polycomb group ring finger 10.039
MPZL1myelin protein zero-like 10.039
SKIv-ski sarcoma viral oncogene homolog (avian)0.039
INADLInaD-like (Drosophila)0.039
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.038
SP1Sp1 transcription factor0.037
NLKnemo-like kinase0.037
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.035
MYOGmyogenin (myogenic factor 4)0.035
MAP3K14mitogen-activated protein kinase kinase kinase 140.035
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.034
NEDD4neural precursor cell expressed, developmentally down-regulated 40.034
MAP2K3mitogen-activated protein kinase kinase 30.033
FGF2fibroblast growth factor 2 (basic)0.033
CFL1cofilin 1 (non-muscle)0.033
BTRCbeta-transducin repeat containing0.032
ZCCHC17zinc finger, CCHC domain containing 170.031
ZBED5zinc finger, BED-type containing 50.031
PRR13proline rich 130.030
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.030
PAFAH1B2platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)0.030
PPP5Cprotein phosphatase 5, catalytic subunit0.030
IGF1Rinsulin-like growth factor 1 receptor0.030
MAXMYC associated factor X0.029
APCadenomatous polyposis coli0.029
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.028
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.028
FKBP5FK506 binding protein 50.028
LHX1LIM homeobox 10.028
PLEKHA7pleckstrin homology domain containing, family A member 70.027
RFWD2ring finger and WD repeat domain 20.027
FOXO3forkhead box O30.027
KRTAP4-12keratin associated protein 4-120.027
LATS1LATS, large tumor suppressor, homolog 1 (Drosophila)0.026
GLIS2GLIS family zinc finger 20.026
GATA4GATA binding protein 40.026
MYL12Amyosin, light chain 12A, regulatory, non-sarcomeric0.026
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.025
GIPC1GIPC PDZ domain containing family, member 10.025
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.025
PTPN12protein tyrosine phosphatase, non-receptor type 120.025
IGSF21immunoglobin superfamily, member 210.025
WWC1WW and C2 domain containing 10.025
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
hnf1baHNF1 homeobox Ba0.993
wnt9awingless-type MMTV integration site family, member 9A0.966
bmp4bone morphogenetic protein 40.843
ndr2nodal-related 20.806
nanos3nanos homolog 30.735
osr2odd-skipped related 2 (Drosophila)0.657
wnt1wingless-type MMTV integration site family, member 10.640
gna12guanine nucleotide binding protein (G protein) alpha 120.637
flhfloating head0.590
pcdh8protocadherin 80.584
wnt4awingless-type MMTV integration site family, member 4a0.571
rarabretinoic acid receptor, alpha b0.550
ventventral expressed homeobox0.549
meis2.1myeloid ecotropic viral integration site 2.10.482
cdh1cadherin 1, epithelial0.468
cldnbclaudin b0.445
shhasonic hedgehog a0.445
dusp6dual specificity phosphatase 60.437
foxa3forkhead box A30.433
pitx2paired-like homeodomain transcription factor 20.427
snai1asnail homolog 1a (Drosophila)0.397
snai1bsnail homolog 1b (Drosophila)0.396
tagln2transgelin 20.393
vedventrally expressed dharma/bozozok antagonist0.393
gata6GATA-binding protein 60.389
sox19bSRY-box containing gene 19b0.388
plcg1phospholipase C, gamma 10.382
rag2recombination activating gene 20.379
bhlhe22basic helix-loop-helix family, member e220.372
ntlano tail a0.348
eya1eyes absent homolog 10.347
fbln1fibulin 10.346
mespamesoderm posterior a0.325
raraaretinoic acid receptor, alpha a0.320
gna13aguanine nucleotide binding protein (G protein), alpha 13a0.301
jag2jagged 20.292
oepone-eyed pinhead0.290
tll1tolloid-like 10.287
sec23aSec23 homolog A (S. cerevisiae)0.278
foxn4forkhead box N40.274
spry2sprouty homolog 20.269
igf1rainsulin-like growth factor 1a receptor0.268
tbx2aT-box gene 2a0.266
sox32SRY-box containing gene 320.257
wnt2bbwingless-type MMTV integration site family, member 2Bb0.254
her5hairy-related 50.243
inhainhibin, alpha0.240
igf3insulin-like growth factor 30.234
etv2ets variant gene 20.227
ftr82finTRIM family, member 820.217
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.213
hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.210
sox2SRY-box containing gene 20.204
rag1recombination activating gene 10.196
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.194
ldb2aLIM-domain binding factor 2a0.185
admpanti-dorsalizing morphogenic protein0.183
fzd5frizzled homolog 50.182
wnt5bwingless-type MMTV integration site family, member 5b0.180
shhbsonic hedgehog b0.180
wt1awilms tumor 1a0.175
wnt11wingless-type MMTV integration site family, member 110.175
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.171
hand2heart and neural crest derivatives expressed transcript 20.168
tbx6T-box gene 60.168
six4bsine oculis homeobox homolog 4b0.167
map2k4amitogen-activated protein kinase kinase 4a0.165
meis3myeloid ecotropic viral integration site 30.165
cldniclaudin i0.164
acvr1bactivin A receptor, type IB0.162
cldngclaudin g0.161
cdh17cadherin 17, LI cadherin (liver-intestine)0.158
hhexhematopoietically expressed homeobox0.157
brd4bromodomain containing 40.155
gnai2lguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like0.155
bmp2bbone morphogenetic protein 2b0.153
zic2bzic family member 2 (odd-paired homolog, Drosophila) b0.149
tbx20T-box 200.148
spry4sprouty (Drosophila) homolog 40.146
cldnhclaudin h0.146
runx2brunt-related transcription factor 2b0.143
tp63tumor protein p630.142
lhx2bLIM homeobox 2b0.140
cntn2contactin 20.139
ptgs1prostaglandin-endoperoxide synthase 10.136
akt2v-akt murine thymoma viral oncogene homolog 20.133
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.133
fgfrl1bfibroblast growth factor receptor-like 1b0.130
bmp15bone morphogenetic protein 150.129
acvr2bactivin receptor IIb0.127
aldh1a2aldehyde dehydrogenase 1 family, member A20.126
vangl2vang-like 2 (van gogh, Drosophila)0.125
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgf8fibroblast growth factor 80.999
Otx2orthodenticle homolog 2 (Drosophila)0.996
Pitx2paired-like homeodomain transcription factor 20.987
Shhsonic hedgehog0.971
Gata4GATA binding protein 40.967
Bmp4bone morphogenetic protein 40.963
Isl1ISL1 transcription factor, LIM/homeodomain0.949
Fgfr2fibroblast growth factor receptor 20.929
Lmx1bLIM homeobox transcription factor 1 beta0.927
Ctnnb1catenin (cadherin associated protein), beta 10.911
Pax8paired box gene 80.890
Smad4MAD homolog 4 (Drosophila)0.856
Gli3GLI-Kruppel family member GLI30.856
Tbx1T-box 10.853
Lhx1LIM homeobox protein 10.848
Pax2paired box gene 20.817
Zic3zinc finger protein of the cerebellum 30.814
Bmpr1abone morphogenetic protein receptor, type 1A0.674
Rargretinoic acid receptor, gamma0.615
Apcadenomatosis polyposis coli0.606
Acvr1activin A receptor, type 10.606
Pitx1paired-like homeodomain transcription factor 10.551
Tbx3T-box 30.544
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.536
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.532
Foxa2forkhead box A20.518
Sox9SRY-box containing gene 90.507
Emx2empty spiracles homolog 2 (Drosophila)0.499
Bmp7bone morphogenetic protein 70.496
Pax3paired box gene 30.496
Ror2receptor tyrosine kinase-like orphan receptor 20.470
Hoxa1homeobox A10.457
Gbx2gastrulation brain homeobox 20.442
Smad6MAD homolog 6 (Drosophila)0.441
Dlx5distal-less homeobox 50.396
Ptpn11protein tyrosine phosphatase, non-receptor type 110.387
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.377
Smad2MAD homolog 2 (Drosophila)0.358
Hoxa13homeobox A130.355
Fgfr1fibroblast growth factor receptor 10.352
Foxh1forkhead box H10.342
Hes1hairy and enhancer of split 1 (Drosophila)0.338
Pou4f2POU domain, class 4, transcription factor 20.328
Gata6GATA binding protein 60.321
Axin1axin 10.297
Hoxd13homeobox D130.279
Meox2mesenchyme homeobox 20.267
Wnt3awingless-related MMTV integration site 3A0.260
Tbx2T-box 20.251
Tgfb2transforming growth factor, beta 20.248
Fgf3fibroblast growth factor 30.245
Hand2heart and neural crest derivatives expressed transcript 20.244
Smad3MAD homolog 3 (Drosophila)0.237
Dok1docking protein 10.227
Lmx1aLIM homeobox transcription factor 1 alpha0.224
Dkk1dickkopf homolog 1 (Xenopus laevis)0.221
Wnt4wingless-related MMTV integration site 40.212
Smad1MAD homolog 1 (Drosophila)0.207
Hand1heart and neural crest derivatives expressed transcript 10.202
Amhr2anti-Mullerian hormone type 2 receptor0.192
Tal1T-cell acute lymphocytic leukemia 10.189
Vegfavascular endothelial growth factor A0.183
Foxc1forkhead box C10.176
Smosmoothened homolog (Drosophila)0.176
Wt1Wilms tumor 1 homolog0.169
Phc2polyhomeotic-like 2 (Drosophila)0.164
Eya1eyes absent 1 homolog (Drosophila)0.161
Rxraretinoid X receptor alpha0.153
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.150
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.149
Ldb2LIM domain binding 20.142
Ptch1patched homolog 10.140
Hoxa10homeobox A100.136
Hoxd3homeobox D30.135
Pcsk5proprotein convertase subtilisin/kexin type 50.131
Shc1src homology 2 domain-containing transforming protein C10.130
Foxa1forkhead box A10.127
Rarbretinoic acid receptor, beta0.118
Fgf10fibroblast growth factor 100.117
Pax6paired box gene 60.114
Efnb2ephrin B20.111
Gsk3bglycogen synthase kinase 3 beta0.111
Wnt5awingless-related MMTV integration site 5A0.110
Hoxb3homeobox B30.110
Cbx2chromobox homolog 2 (Drosophila Pc class)0.109
Ascl1achaete-scute complex homolog 1 (Drosophila)0.107
Tcfap2atranscription factor AP-2, alpha0.100
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.099
Nkx2-1NK2 homeobox 10.097
Vangl2vang-like 2 (van gogh, Drosophila)0.093
Jag1jagged 10.093
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.091
Sox7SRY-box containing gene 70.091
Alx4aristaless-like homeobox 40.088
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.086
Foxf2forkhead box F20.085
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism