The network for 'negative regulation of neural precursor cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of neural precursor cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.

NameDescriptionProbabilityFunc Analog Organism
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.999
CCT8chaperonin containing TCP1, subunit 8 (theta)0.982
TAL1T-cell acute lymphocytic leukemia 10.922
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.863
ARID1BAT rich interactive domain 1B (SWI1-like)0.671
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.652
TCP1t-complex 10.619
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.443
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.410
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.409
BCORBCL6 corepressor0.373
ETFAelectron-transfer-flavoprotein, alpha polypeptide0.367
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.356
MED10mediator complex subunit 100.322
IL1R1interleukin 1 receptor, type I0.264
NCK2NCK adaptor protein 20.249
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.238
COX6Ccytochrome c oxidase subunit VIc0.237
ARID1AAT rich interactive domain 1A (SWI-like)0.221
ATP5IATP synthase, H+ transporting, mitochondrial Fo complex, subunit E0.216
CCT4chaperonin containing TCP1, subunit 4 (delta)0.208
MED28mediator complex subunit 280.174
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.146
PARVAparvin, alpha0.145
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.142
MDM2Mdm2 p53 binding protein homolog (mouse)0.128
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.126
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.124
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.119
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.115
ILKintegrin-linked kinase0.112
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.108
PPP2R2Cprotein phosphatase 2, regulatory subunit B, gamma0.103
CDK8cyclin-dependent kinase 80.101
MECP2methyl CpG binding protein 2 (Rett syndrome)0.099
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.095
SKA3spindle and kinetochore associated complex subunit 30.093
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.086
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.079
NCOR1nuclear receptor corepressor 10.077
TGFBR1transforming growth factor, beta receptor 10.076
JUPjunction plakoglobin0.075
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.073
IL1RAPinterleukin 1 receptor accessory protein0.071
CCT7chaperonin containing TCP1, subunit 7 (eta)0.071
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.066
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.066
PPP4Cprotein phosphatase 4, catalytic subunit0.064
CREBBPCREB binding protein0.061
NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa0.060
FSTL1follistatin-like 10.059
SKIv-ski sarcoma viral oncogene homolog (avian)0.057
PBRM1polybromo 10.057
COX7Ccytochrome c oxidase subunit VIIc0.056
HDAC6histone deacetylase 60.054
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.054
YY1YY1 transcription factor0.053
NAP1L1nucleosome assembly protein 1-like 10.050
ZMYND11zinc finger, MYND-type containing 110.050
COX5Bcytochrome c oxidase subunit Vb0.048
MED27mediator complex subunit 270.046
VDAC2voltage-dependent anion channel 20.045
ZC3HAV1zinc finger CCCH-type, antiviral 10.044
MED30mediator complex subunit 300.043
SMAD2SMAD family member 20.043
KLF13Kruppel-like factor 130.043
SMAD1SMAD family member 10.042
PSEN1presenilin 10.040
RUNX1runt-related transcription factor 10.040
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.040
APCadenomatous polyposis coli0.038
TBX5T-box 50.037
IL8interleukin 80.037
GATA2GATA binding protein 20.034
SMAD7SMAD family member 70.034
MED19mediator complex subunit 190.034
BTRCbeta-transducin repeat containing0.034
COX7Bcytochrome c oxidase subunit VIIb0.033
PRKCZprotein kinase C, zeta0.033
CTNND1catenin (cadherin-associated protein), delta 10.033
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.032
ZFPM1zinc finger protein, multitype 10.031
PPP2R2Bprotein phosphatase 2, regulatory subunit B, beta0.031
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.031
HIPK2homeodomain interacting protein kinase 20.031
CXCL2chemokine (C-X-C motif) ligand 20.031
PARVBparvin, beta0.029
SERTAD4SERTA domain containing 40.029
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.029
NEDD9neural precursor cell expressed, developmentally down-regulated 90.029
CTBP1C-terminal binding protein 10.029
LIMS1LIM and senescent cell antigen-like domains 10.029
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.029
MED29mediator complex subunit 290.028
CCNCcyclin C0.027
MYOD1myogenic differentiation 10.027
IL1RNinterleukin 1 receptor antagonist0.027
GATA1GATA binding protein 1 (globin transcription factor 1)0.027
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ilkintegrin linked kinase0.787
pax6apaired box gene 6a0.530
otpborthopedia homolog b0.396
prox1prospero-related homeobox gene 10.322
nr2e1nuclear receptor subfamily 2, group E, member 10.240
lama4laminin, alpha 40.184
nf1aneurofibromin 1a0.165
neurodneurogenic differentiation0.164
tia1cytotoxic granule-associated RNA binding protein 10.164
nf1bneurofibromin 1b0.155
mab21l2mab-21-like 20.149
asb2bankyrin repeat and SOCS box-containing 2b0.147
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.131
meis2.2myeloid ecotropic viral integration site 2.20.129
arxaristaless related homeobox0.128
irf2bp2binterferon regulatory factor 2 binding protein 2b0.118
irx4airoquois homeobox protein 4a0.110
neurog1neurogenin 10.106
dio2deiodinase, iodothyronine, type II0.101
sox2SRY-box containing gene 20.099
nkx2.1aNK2 homeobox 1a0.096
metmet proto-oncogene (hepatocyte growth factor receptor)0.089
angptl3angiopoietin-like 30.085
olig2oligodendrocyte lineage transcription factor 20.084
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.079
ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)0.078
spry4sprouty (Drosophila) homolog 40.077
ascl1aachaete-scute complex-like 1a (Drosophila)0.076
nkx2.2aNK2 transcription factor related 2a0.074
pax6bpaired box gene 6b0.070
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.067
emx1empty spiracles homeobox 10.063
tpst1tyrosylprotein sulfotransferase 10.063
mef2amyocyte enhancer factor 2a0.060
disp1dispatched homolog 1 (Drosophila)0.060
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.059
ube2i2ubiquitin-conjugating enzyme E2I20.057
foxn4forkhead box N40.056
etfaelectron-transfer-flavoprotein, alpha polypeptide0.053
lsrlipolysis stimulated lipoprotein receptor0.053
cadm3cell adhesion molecule 30.052
llgl2lethal giant larvae homolog 2 (Drosophila)0.050
kiss2kisspeptin 20.050
cap2CAP, adenylate cyclase-associated protein, 2 (yeast)0.050
cnot8CCR4-NOT transcription complex, subunit 80.049
her6hairy-related 60.049
cox6a1cytochrome c oxidase subunit VIa polypeptide 10.048
vsx2visual system homeobox 20.046
trim55atripartite motif-containing 55a0.045
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.045
ccng1cyclin G10.045
akt2lv-akt murine thymoma viral oncogene homolog 2, like0.044
tnni2a.3troponin I, skeletal, fast 2a.30.044
rgs4regulator of G-protein signalling 40.043
agxtaalanine-glyoxylate aminotransferase a0.043
btg1B-cell translocation gene 10.043
wdr45lwdr45 like0.043
lama2laminin, alpha 20.043
cox4i2cytochrome c oxidase subunit IV isoform 20.043
rrasrelated RAS viral (r-ras) oncogene homolog0.042
kiss1KiSS-1 metastasis-suppressor0.042
wdr82WD repeat domain containing 820.041
aurkbaurora kinase B0.041
thoc1THO complex 10.040
pcp4aPurkinje cell protein 4a0.040
smad5MAD homolog 5 (Drosophila)0.040
fhfumarate hydratase0.040
fezf2FEZ family zinc finger 20.039
hs6st1aheparan sulfate 6-O-sulfotransferase 1a0.039
olig4oligodendrocyte transcription factor 40.038
prkciprotein kinase C, iota0.036
igf2binsulin-like growth factor 2b0.036
notch3notch homolog 30.036
neurod4neurogenic differentiation 40.036
sox21bSRY-box containing gene 21 b0.035
ppm1fprotein phosphatase 1F (PP2C domain containing)0.035
ptrfbpolymerase I and transcript release factor b0.035
crabp2bcellular retinoic acid binding protein 2, b0.034
elmo1engulfment and cell motility 1 (ced-12 homolog, C. elegans)0.033
trpm7transient receptor potential cation channel, subfamily M, member 70.032
chd7chromodomain helicase DNA binding protein 70.032
leo1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.032
birc2baculoviral IAP repeat-containing 20.032
lamb2laminin, beta 2 (laminin S)0.031
robo3roundabout homolog 30.031
esamaendothelial cell adhesion molecule a0.031
mef2camyocyte enhancer factor 2ca0.031
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.030
sarsseryl-tRNA synthetase0.030
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.030
slco1d1solute carrier organic anion transporter family, member 1D10.030
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
MED11Mediator complex subunit 110.990
MED27Mediator complex subunit 270.983
MED10Mediator complex subunit 100.978
MED9Mediator complex subunit 90.968
MED6Mediator complex subunit 60.954
MED4Mediator complex subunit 40.891
skpACG16983 gene product from transcript CG16983-RD0.837
Uba1Ubiquitin activating enzyme 10.787
bratbrain tumor0.786
MED31Mediator complex subunit 310.744
stcksteamer duck0.293
drkdownstream of receptor kinase0.237
eyaeyes absent0.201
hydhyperplastic discs0.179
crolcrooked legs0.153
SAKSak kinase0.137
Mov34CG3416 gene product from transcript CG3416-RA0.136
osaCG7467 gene product from transcript CG7467-RD0.131
jebjelly belly0.121
RhoGAP100FCG1976 gene product from transcript CG1976-RB0.121
slmbsupernumerary limbs0.108
ctpcut up0.108
Pk61CProtein kinase 61C0.106
ash2absent, small, or homeotic discs 20.103
numbCG3779 gene product from transcript CG3779-RB0.099
cpacapping protein alpha0.098
spensplit ends0.095
CG2608CG2608 gene product from transcript CG2608-RA0.086
Cdk8Cyclin-dependent kinase 80.078
Su(H)Suppressor of Hairless0.075
Elongin-CElongin C0.071
bowlbrother of odd with entrails limited0.066
CycJCyclin J0.061
l(2)gllethal (2) giant larvae0.056
dvedefective proventriculus0.055
CG5214CG5214 gene product from transcript CG5214-RA0.055
CG7834CG7834 gene product from transcript CG7834-RA0.054
CSN8COP9 complex homolog subunit 80.054
maf-SCG9954 gene product from transcript CG9954-RA0.050
InRInsulin-like receptor0.050
MED17Mediator complex subunit 170.049
CG7712CG7712 gene product from transcript CG7712-RA0.049
Stat92ESignal-transducer and activator of transcription protein at 92E0.049
Bap60Brahma associated protein 60kD0.048
Kr-h1Kruppel homolog 10.048
Actnalpha actinin0.045
CycECyclin E0.044
ScmSex comb on midleg0.044
Nrx-1Neurexin 10.043
ponpartner of numb0.042
CG3321CG3321 gene product from transcript CG3321-RC0.041
G-salpha60AG protein salpha 60A0.041
MED7Mediator complex subunit 70.038
shotshort stop0.037
CG11455CG11455 gene product from transcript CG11455-RB0.037
Sin3ACG8815 gene product from transcript CG8815-RC0.036
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.036
CG34439CG34439 gene product from transcript CG34439-RB0.036
RdlResistant to dieldrin0.035
CG14235CG14235 gene product from transcript CG14235-RA0.035
CG1970CG1970 gene product from transcript CG1970-RA0.033
Chrac-14CG13399 gene product from transcript CG13399-RA0.033
IlkIntegrin linked kinase0.032
CG17059CG17059 gene product from transcript CG17059-RA0.031
Nedd8CG10679 gene product from transcript CG10679-RA0.031
l(2)35Dilethal (2) 35Di0.030
CG3305CG3305 gene product from transcript CG3305-RA0.030
CG3192CG3192 gene product from transcript CG3192-RA0.030
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.917
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.851
Rb1retinoblastoma 10.817
Emx1empty spiracles homolog 1 (Drosophila)0.796
Rxraretinoid X receptor alpha0.739
Ptenphosphatase and tensin homolog0.737
Shhsonic hedgehog0.707
Ctnnb1catenin (cadherin associated protein), beta 10.666
Arid1bAT rich interactive domain 1B (SWI-like)0.654
Id1inhibitor of DNA binding 10.638
Isl1ISL1 transcription factor, LIM/homeodomain0.621
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.572
Id3inhibitor of DNA binding 30.544
Tcf3transcription factor 30.541
Fgfr2fibroblast growth factor receptor 20.474
Ptpn11protein tyrosine phosphatase, non-receptor type 110.444
Egfrepidermal growth factor receptor0.324
Gata4GATA binding protein 40.311
Itgb1integrin beta 1 (fibronectin receptor beta)0.309
Sox2SRY-box containing gene 20.298
Pax3paired box gene 30.287
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.265
Mdm2transformed mouse 3T3 cell double minute 20.248
Efnb2ephrin B20.247
Chd7chromodomain helicase DNA binding protein 70.209
Vegfavascular endothelial growth factor A0.207
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.206
Cdkn1bcyclin-dependent kinase inhibitor 1B0.175
Hey2hairy/enhancer-of-split related with YRPW motif 20.174
Grb2growth factor receptor bound protein 20.159
Arid1aAT rich interactive domain 1A (SWI-like)0.158
Apcadenomatosis polyposis coli0.152
E2f1E2F transcription factor 10.151
Klf3Kruppel-like factor 3 (basic)0.147
Foxc1forkhead box C10.141
Rnf2ring finger protein 20.139
Hand2heart and neural crest derivatives expressed transcript 20.135
Hif1ahypoxia inducible factor 1, alpha subunit0.133
Fgf8fibroblast growth factor 80.133
Otx2orthodenticle homolog 2 (Drosophila)0.127
Notch1Notch gene homolog 1 (Drosophila)0.121
Pitx2paired-like homeodomain transcription factor 20.120
Sox4SRY-box containing gene 40.117
Emx2empty spiracles homolog 2 (Drosophila)0.114
Hoxa1homeobox A10.100
Jag1jagged 10.099
Ntf3neurotrophin 30.098
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.091
Pax6paired box gene 60.087
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.085
BrafBraf transforming gene0.081
Parvaparvin, alpha0.076
Myl9myosin, light polypeptide 9, regulatory0.074
Rararetinoic acid receptor, alpha0.070
Lims1LIM and senescent cell antigen-like domains 10.069
Nos3nitric oxide synthase 3, endothelial cell0.068
Cdkn2acyclin-dependent kinase inhibitor 2A0.068
Kitkit oncogene0.067
Zfpm2zinc finger protein, multitype 20.067
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.065
Tbx3T-box 30.063
Bmp4bone morphogenetic protein 40.061
Pax2paired box gene 20.061
Gata6GATA binding protein 60.061
Lef1lymphoid enhancer binding factor 10.058
Retret proto-oncogene0.057
Gli3GLI-Kruppel family member GLI30.055
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.052
Trp63transformation related protein 630.052
Ilkintegrin linked kinase0.051
Smad6MAD homolog 6 (Drosophila)0.049
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.048
FosFBJ osteosarcoma oncogene0.048
Fgf10fibroblast growth factor 100.045
Smarcb1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.043
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.042
Neurod1neurogenic differentiation 10.041
Tbx1T-box 10.040
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.039
Arandrogen receptor0.039
Nrg1neuregulin 10.039
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.038
Hes1hairy and enhancer of split 1 (Drosophila)0.038
Igbp1immunoglobulin (CD79A) binding protein 10.036
Egr3early growth response 30.035
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.035
Bmpr1abone morphogenetic protein receptor, type 1A0.034
Vhlvon Hippel-Lindau tumor suppressor0.034
Psen1presenilin 10.033
Mesp1mesoderm posterior 10.033
Mdm4transformed mouse 3T3 cell double minute 40.032
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.031
Tcf4transcription factor 40.031
Runx1runt related transcription factor 10.031
Bdnfbrain derived neurotrophic factor0.030
Tgfb2transforming growth factor, beta 20.030
Adam17a disintegrin and metallopeptidase domain 170.030
Tcfap2atranscription factor AP-2, alpha0.030
Tal1T-cell acute lymphocytic leukemia 10.030
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism