The network for 'positive regulation of neural precursor cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of neural precursor cell proliferation

Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.

NameDescriptionProbabilityFunc Analog Organism
PAX3paired box 30.984
POU3F2POU class 3 homeobox 20.953
JAG1jagged 10.830
NRP1neuropilin 10.724
FGFR1fibroblast growth factor receptor 10.700
NCK1NCK adaptor protein 10.699
SOS1son of sevenless homolog 1 (Drosophila)0.616
SNAP25synaptosomal-associated protein, 25kDa0.580
AXIN1axin 10.568
NOTCH3notch 30.561
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.505
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.492
POU5F1POU class 5 homeobox 10.490
CYFIP2cytoplasmic FMR1 interacting protein 20.436
ADORA2Aadenosine A2a receptor0.429
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.372
HNF4Ahepatocyte nuclear factor 4, alpha0.342
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.339
PLCG1phospholipase C, gamma 10.325
MEOX2mesenchyme homeobox 20.325
FOXD3forkhead box D30.314
ATP13A2ATPase type 13A20.280
PGFplacental growth factor0.277
NCOR2nuclear receptor corepressor 20.275
CYFIP1cytoplasmic FMR1 interacting protein 10.250
NR4A1nuclear receptor subfamily 4, group A, member 10.244
GABARAPGABA(A) receptor-associated protein0.219
STK36serine/threonine kinase 360.216
PAX6paired box 60.211
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.202
LRP6low density lipoprotein receptor-related protein 60.201
TRAF3IP1TNF receptor-associated factor 3 interacting protein 10.167
MAP1Amicrotubule-associated protein 1A0.164
METmet proto-oncogene (hepatocyte growth factor receptor)0.163
SUV39H1suppressor of variegation 3-9 homolog 1 (Drosophila)0.155
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.150
GSK3Bglycogen synthase kinase 3 beta0.150
OLIG2oligodendrocyte lineage transcription factor 20.142
FGF1fibroblast growth factor 1 (acidic)0.140
ESR1estrogen receptor 10.138
MAML1mastermind-like 1 (Drosophila)0.136
EPAS1endothelial PAS domain protein 10.123
NAMPTnicotinamide phosphoribosyltransferase0.122
KAT2BK(lysine) acetyltransferase 2B0.122
SPTBN4spectrin, beta, non-erythrocytic 40.121
KIF18Akinesin family member 18A0.119
SALL2sal-like 2 (Drosophila)0.118
APCadenomatous polyposis coli0.117
SOX1SRY (sex determining region Y)-box 10.114
SYNE1spectrin repeat containing, nuclear envelope 10.113
IGFBP3insulin-like growth factor binding protein 30.109
EGLN3egl nine homolog 3 (C. elegans)0.107
EGLN1egl nine homolog 1 (C. elegans)0.107
TNIP2TNFAIP3 interacting protein 20.106
HES2hairy and enhancer of split 2 (Drosophila)0.105
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.103
INPPL1inositol polyphosphate phosphatase-like 10.101
ARHGAP31Rho GTPase activating protein 310.101
LHX2LIM homeobox 20.099
RGS3regulator of G-protein signaling 30.099
SOX11SRY (sex determining region Y)-box 110.099
BIN1bridging integrator 10.092
BCL6B-cell CLL/lymphoma 60.091
CTNND1catenin (cadherin-associated protein), delta 10.089
ACTN2actinin, alpha 20.088
NR5A2nuclear receptor subfamily 5, group A, member 20.086
SUV39H2suppressor of variegation 3-9 homolog 2 (Drosophila)0.083
LDLRlow density lipoprotein receptor0.083
FOXO1forkhead box O10.082
FZD1frizzled homolog 1 (Drosophila)0.080
LAMC3laminin, gamma 30.080
KALRNkalirin, RhoGEF kinase0.079
KCTD4potassium channel tetramerisation domain containing 40.079
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.076
CADM4cell adhesion molecule 40.076
DLL1delta-like 1 (Drosophila)0.074
COL2A1collagen, type II, alpha 10.072
NCOA2nuclear receptor coactivator 20.072
SIX3SIX homeobox 30.071
DEPDC1DEP domain containing 10.071
GRB10growth factor receptor-bound protein 100.071
LBX1ladybird homeobox 10.070
SAMD3sterile alpha motif domain containing 30.069
SHC1SHC (Src homology 2 domain containing) transforming protein 10.069
LCMT1leucine carboxyl methyltransferase 10.068
MEMO1mediator of cell motility 10.067
FZD8frizzled homolog 8 (Drosophila)0.066
CCDC141coiled-coil domain containing 1410.066
RAXretina and anterior neural fold homeobox0.066
NOTCH2notch 20.065
JUPjunction plakoglobin0.065
ARHGAP11ARho GTPase activating protein 11A0.065
STC1stanniocalcin 10.065
OTPorthopedia homeobox0.064
FOXO3forkhead box O30.064
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.063
HDAC2histone deacetylase 20.063
NCOA6nuclear receptor coactivator 60.063
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
notch1anotch homolog 1a0.988
ascl1aachaete-scute complex-like 1a (Drosophila)0.945
gli2aGLI-Kruppel family member GLI2a0.936
pax2apaired box gene 2a0.898
hey1hairy/enhancer-of-split related with YRPW motif 10.814
her6hairy-related 60.814
pax6bpaired box gene 6b0.791
cdh2cadherin 2, neuronal0.788
her15.1hairy and enhancer of split-related 15.10.788
lfnglunatic fringe homolog0.708
nkx2.2aNK2 transcription factor related 2a0.702
pax6apaired box gene 6a0.697
notch3notch homolog 30.641
nr2e1nuclear receptor subfamily 2, group E, member 10.596
pitx3paired-like homeodomain transcription factor 30.583
vsx2visual system homeobox 20.540
gli1GLI-Kruppel family member 10.515
eya1eyes absent homolog 10.507
lhx1aLIM homeobox 1a0.462
otx2orthodenticle homolog 20.349
otpborthopedia homolog b0.343
insm1ainsulinoma-associated 1a0.297
axin2axin 2 (conductin, axil)0.293
her4.2hairy-related 4.20.291
msxcmuscle segment homeobox C0.275
pea3ETS-domain transcription factor pea30.267
ptgs1prostaglandin-endoperoxide synthase 10.266
lmx1b.1LIM homeobox transcription factor 1, beta 10.264
mab21l2mab-21-like 20.264
fezf2FEZ family zinc finger 20.263
neurog1neurogenin 10.250
ascl1bachaete-scute complex-like 1b (Drosophila)0.250
barhl2BarH-like 20.241
dmrt3adoublesex and mab-3 related transcription factor 3a0.239
her8ahairy-related 8a0.236
cxcr4achemokine (C-X-C motif) receptor 4a0.233
rad21RAD21 homolog (S. pombe)0.222
neo1neogenin 10.212
her3hairy-related 30.211
fabp7afatty acid binding protein 7, brain, a0.211
hoxa9ahomeo box A9a0.204
aplnrbapelin receptor b0.193
sox19aSRY-box containing gene 19a0.191
foxj1aforkhead box J1a0.190
tbx6T-box gene 60.190
irx7iroquois homeobox protein 70.187
hmx4H6 family homeobox 40.186
st8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.184
tbx16T-box gene 160.175
traf4atnf receptor-associated factor 4a0.173
atoh7atonal homolog 70.170
wnt1wingless-type MMTV integration site family, member 10.158
rx2retinal homeobox gene 20.157
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.156
scube2signal peptide, CUB domain, EGF-like 20.152
sp7Sp7 transcription factor0.147
dbx1adeveloping brain homeobox 1a0.144
otx1aorthodenticle homolog 1a0.141
irx4airoquois homeobox protein 4a0.140
neurodneurogenic differentiation0.137
vcanaversican a0.136
mibmind bomb0.135
fgf8afibroblast growth factor 8 a0.132
eng2aengrailed 2a0.131
olig3oligodendrocyte transcription factor 30.130
axin1axin 10.130
her1hairy-related 10.130
chd7chromodomain helicase DNA binding protein 70.129
znf703zinc finger protein 7030.126
lhx3LIM homeobox 30.126
bmp2bbone morphogenetic protein 2b0.119
olig2oligodendrocyte lineage transcription factor 20.119
foxn4forkhead box N40.119
supt6hsuppressor of Ty 6 homolog0.118
foxd5forkhead box D50.114
fzd7afrizzled homolog 7a0.113
sox3SRY-box containing gene 30.112
foxp2forkhead box P20.111
wt1bwilms tumor 1b0.110
sox1aSRY-box containing gene 1a0.108
gli2bGLI-Kruppel family member GLI2b0.108
her2hairy-related 20.108
pkd2polycystic kidney disease 20.107
foxi1forkhead box I10.106
jag2jagged 20.103
cxcr4bchemokine (C-X-C motif), receptor 4b0.099
col18a1collagen type XVIII, alpha 10.097
dag1dystroglycan 10.095
six3asine oculis homeobox homolog 3a0.095
tbx24T-box 240.091
hes6hairy and enhancer of split 6 (Drosophila)0.090
her12hairy-related 120.089
nrarpanotch-regulated ankyrin repeat protein a0.089
pcnaproliferating cell nuclear antigen0.089
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
E(spl)Enhancer of split0.836
HLHmgammaE(spl) region transcript mgamma0.662
HLHm7E(spl) region transcript m70.626
jingCG9397 gene product from transcript CG9397-RI0.245
Fas2Fasciclin 20.215
HLHmbetaE(spl) region transcript mbeta0.202
HLHmdeltaE(spl) region transcript mdelta0.160
m2E(spl) region transcript m20.115
HLHm5E(spl) region transcript m50.104
HLHm3E(spl) region transcript m30.084
slp1sloppy paired 10.070
malphaE(spl) region transcript malpha0.050
EgfrEpidermal growth factor receptor0.040
aopanterior open0.038
cicubitus interruptus0.035
fz2frizzled 20.030
m4E(spl) region transcript m40.027
CG3563CG3563 gene product from transcript CG3563-RA0.025
Ras85DRas oncogene at 85D0.020
Ced-12CG5336 gene product from transcript CG5336-RA0.017
stanstarry night0.015
Socs36ESuppressor of cytokine signaling at 36E0.014
jubAjuba LIM protein0.014
InRInsulin-like receptor0.014
PoxnPox neuro0.014
unc-104CG8566 gene product from transcript CG8566-RB0.014
ovoCG6824 gene product from transcript CG6824-RE0.014
Stat92ESignal-transducer and activator of transcription protein at 92E0.013
NotumCG13076 gene product from transcript CG13076-RB0.013
robo3CG5423 gene product from transcript CG5423-RA0.012
sut1sugar transporter 10.011
unc-5CG8166 gene product from transcript CG8166-RA0.010
Akt1CG4006 gene product from transcript CG4006-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Otx2orthodenticle homolog 2 (Drosophila)0.996
Pax3paired box gene 30.993
Gli3GLI-Kruppel family member GLI30.992
Fgfr2fibroblast growth factor receptor 20.992
Foxc1forkhead box C10.990
Pax6paired box gene 60.988
Emx2empty spiracles homolog 2 (Drosophila)0.980
Pax2paired box gene 20.961
Pitx2paired-like homeodomain transcription factor 20.959
Fgf8fibroblast growth factor 80.953
Foxc2forkhead box C20.921
Fgf10fibroblast growth factor 100.920
Emx1empty spiracles homolog 1 (Drosophila)0.908
Bmp4bone morphogenetic protein 40.868
Ascl1achaete-scute complex homolog 1 (Drosophila)0.868
Gli2GLI-Kruppel family member GLI20.839
Sox3SRY-box containing gene 30.835
Eya1eyes absent 1 homolog (Drosophila)0.804
Egfrepidermal growth factor receptor0.730
Rargretinoic acid receptor, gamma0.720
Pax8paired box gene 80.709
Lmx1bLIM homeobox transcription factor 1 beta0.699
Insm1insulinoma-associated 10.694
Retret proto-oncogene0.684
Dkk1dickkopf homolog 1 (Xenopus laevis)0.684
Mitfmicrophthalmia-associated transcription factor0.662
Nkx2-1NK2 homeobox 10.657
Neurod1neurogenic differentiation 10.652
Tcfap2atranscription factor AP-2, alpha0.644
Fgfr1fibroblast growth factor receptor 10.641
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.641
Myod1myogenic differentiation 10.629
Hoxd11homeobox D110.618
Ptpn11protein tyrosine phosphatase, non-receptor type 110.609
Gbx2gastrulation brain homeobox 20.598
Meox2mesenchyme homeobox 20.593
Hes1hairy and enhancer of split 1 (Drosophila)0.588
Foxg1forkhead box G10.573
Efnb2ephrin B20.549
Chd7chromodomain helicase DNA binding protein 70.548
Foxa2forkhead box A20.540
Tgfb2transforming growth factor, beta 20.539
Sox2SRY-box containing gene 20.531
Mef2dmyocyte enhancer factor 2D0.523
Nos3nitric oxide synthase 3, endothelial cell0.520
Lhx3LIM homeobox protein 30.511
Onecut1one cut domain, family member 10.496
Pou3f3POU domain, class 3, transcription factor 30.470
Notch1Notch gene homolog 1 (Drosophila)0.465
Pkd1polycystic kidney disease 1 homolog0.459
Tbx3T-box 30.454
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.454
Ror2receptor tyrosine kinase-like orphan receptor 20.447
Pthlhparathyroid hormone-like peptide0.447
Lhx1LIM homeobox protein 10.445
Flt4FMS-like tyrosine kinase 40.427
Neurog2neurogenin 20.423
Ctnnb1catenin (cadherin associated protein), beta 10.417
Sox11SRY-box containing gene 110.415
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.408
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.404
Vegfavascular endothelial growth factor A0.401
Wnt1wingless-related MMTV integration site 10.384
Isl1ISL1 transcription factor, LIM/homeodomain0.365
Sox7SRY-box containing gene 70.363
Wnt3awingless-related MMTV integration site 3A0.357
Twist2twist homolog 2 (Drosophila)0.354
Notch2Notch gene homolog 2 (Drosophila)0.354
Wnt7bwingless-related MMTV integration site 7B0.344
Sox9SRY-box containing gene 90.341
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.316
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.315
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.315
Hand2heart and neural crest derivatives expressed transcript 20.315
Lmx1aLIM homeobox transcription factor 1 alpha0.298
Hand1heart and neural crest derivatives expressed transcript 10.295
Jag2jagged 20.293
Ptenphosphatase and tensin homolog0.292
Otx1orthodenticle homolog 1 (Drosophila)0.288
Sall3sal-like 3 (Drosophila)0.274
Smad6MAD homolog 6 (Drosophila)0.268
Hoxd9homeobox D90.252
Vangl2vang-like 2 (van gogh, Drosophila)0.250
Igfbpl1insulin-like growth factor binding protein-like 10.249
Pou3f1POU domain, class 3, transcription factor 10.243
Rb1retinoblastoma 10.243
Gata4GATA binding protein 40.242
Pax1paired box gene 10.242
Foxb1forkhead box B10.235
Dll1delta-like 1 (Drosophila)0.232
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.228
Fgf3fibroblast growth factor 30.227
Grb10growth factor receptor bound protein 100.226
Gopcgolgi associated PDZ and coiled-coil motif containing0.225
Wnt5awingless-related MMTV integration site 5A0.220
Tgfatransforming growth factor alpha0.219
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Sirpasignal-regulatory protein alpha0.165
Ptprcprotein tyrosine phosphatase, receptor type, C0.137
Adora2aadenosine A2a receptor0.081
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.080
Bex4brain expressed, X-linked 40.079
Cd4Cd4 molecule0.076
Lamc1laminin, gamma 10.076
Fgfr2fibroblast growth factor receptor 20.067
Flt1FMS-related tyrosine kinase 10.053
Pls3plastin 3 (T-isoform)0.043
Ptafrplatelet-activating factor receptor0.038
Il8rbinterleukin 8 receptor, beta0.037
Jak1Janus kinase 10.036
GperG protein-coupled estrogen receptor 10.027
Ebf1early B-cell factor 10.025
Gja4gap junction protein, alpha 40.025
Pecam1platelet/endothelial cell adhesion molecule 10.024
Ddr1discoidin domain receptor tyrosine kinase 10.023
Cd38CD38 molecule0.023
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.023
NrarpNotch-regulated ankyrin repeat protein0.023
Gna15guanine nucleotide binding protein, alpha 150.023
C3complement component 30.022
Myh9myosin, heavy chain 9, non-muscle0.022
Unc5bunc-5 homolog B (C. elegans)0.021
Cxcr3chemokine (C-X-C motif) receptor 30.021
Itpr2inositol 1,4,5-triphosphate receptor, type 20.020
Cd247Cd247 molecule0.019
Cd5Cd5 molecule0.019
Nfibnuclear factor I/B0.019
Galr3galanin receptor 30.018
Dgkgdiacylglycerol kinase, gamma0.018
Ecel1endothelin converting enzyme-like 10.018
Tgfbr3transforming growth factor, beta receptor III0.018
Cd37CD37 molecule0.017
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.017
Ptger2prostaglandin E receptor 2 (subtype EP2)0.017
Cx3cr1chemokine (C-X3-C motif) receptor 10.016
Nek9NIMA (never in mitosis gene a)- related kinase 90.016
Sox17SRY (sex determining region Y)-box 170.016
Il1binterleukin 1 beta0.015
Gfapglial fibrillary acidic protein0.015
Olr1413olfactory receptor 14130.015
Pde5aphosphodiesterase 5A, cGMP-specific0.015
Efnb1ephrin B10.015
Metmet proto-oncogene0.015
Fam65bfamily with sequence similarity 65, member B0.015
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.014
Ascl1achaete-scute complex homolog 1 (Drosophila)0.014
Acvr1activin A receptor, type I0.014
Smad1SMAD family member 10.013
Itgamintegrin, alpha M0.013
Mobkl2aMOB1, Mps One Binder kinase activator-like 2A (yeast)0.013
Fgfr1Fibroblast growth factor receptor 10.013
Ptpn6protein tyrosine phosphatase, non-receptor type 60.013
Ccl20chemokine (C-C motif) ligand 200.013
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.013
Ccl3chemokine (C-C motif) ligand 30.013
Itpr3inositol 1,4,5-triphosphate receptor, type 30.013
Egfrepidermal growth factor receptor0.013
St18suppression of tumorigenicity 180.013
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.013
Agtr1aangiotensin II receptor, type 1a0.012
Il2rginterleukin 2 receptor, gamma0.012
Neurl3neuralized homolog 3 (Drosophila)0.012
Drd3dopamine receptor D30.012
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.012
Nrasneuroblastoma ras oncogene0.012
LOC679840similar to germinal histone H4 gene0.012
Dchs1dachsous 1 (Drosophila)0.012
Klhl6kelch-like 6 (Drosophila)0.012
Smad7SMAD family member 70.012
Megf6multiple EGF-like-domains 60.012
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.012
Ghrgrowth hormone receptor0.012
Hif1ahypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.012
Foxs1forkhead box S10.011
Samsn1SAM domain, SH3 domain and nuclear localization signals, 10.011
Pde6hphosphodiesterase 6H, cGMP-specific, cone, gamma0.011
Prph2peripherin 20.011
Prkcdprotein kinase C, delta0.011
Ngfrap1nerve growth factor receptor (TNFRSF16) associated protein 10.011
Cgaglycoprotein hormones, alpha polypeptide0.011
Col8a1collagen, type VIII, alpha 10.011
Atxn1ataxin 10.010
Glra1glycine receptor, alpha 10.010
Myo1gmyosin IG0.010
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.010
Inpp5dinositol polyphosphate-5-phosphatase D0.010
Lilrb4leukocyte immunoglobulin-like receptor, subfamily B, member 40.010
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism