The network for 'regulation of actin filament based process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of actin filament based process

Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.

NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
GRB2growth factor receptor-bound protein 21.000
ARHGDIARho GDP dissociation inhibitor (GDI) alpha1.000
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)1.000
RHOAras homolog gene family, member A1.000
FYNFYN oncogene related to SRC, FGR, YES1.000
ACTBactin, beta0.999
SFNstratifin0.996
MDM2Mdm2 p53 binding protein homolog (mouse)0.994
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.993
EGFRepidermal growth factor receptor0.992
CFL1cofilin 1 (non-muscle)0.992
ABI1abl-interactor 10.990
GAS7growth arrest-specific 70.988
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.982
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.981
MYH9myosin, heavy chain 9, non-muscle0.980
JUPjunction plakoglobin0.977
BAIAP2BAI1-associated protein 20.975
NCK1NCK adaptor protein 10.970
IQGAP1IQ motif containing GTPase activating protein 10.969
SH3KBP1SH3-domain kinase binding protein 10.969
ZYXzyxin0.965
FLNAfilamin A, alpha0.955
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.951
VAV1vav 1 guanine nucleotide exchange factor0.946
TPM1tropomyosin 1 (alpha)0.945
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.937
WASLWiskott-Aldrich syndrome-like0.935
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.924
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.920
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.918
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.917
DLG4discs, large homolog 4 (Drosophila)0.905
ZNF746zinc finger protein 7460.889
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.889
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.888
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.884
ILKintegrin-linked kinase0.883
PKP3plakophilin 30.868
CALM1calmodulin 1 (phosphorylase kinase, delta)0.854
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.849
S100A9S100 calcium binding protein A90.846
ITSN1intersectin 1 (SH3 domain protein)0.843
SPRR2Asmall proline-rich protein 2A0.841
NCKAP1NCK-associated protein 10.812
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.803
SMAD2SMAD family member 20.793
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.775
RASA1RAS p21 protein activator (GTPase activating protein) 10.774
SOS1son of sevenless homolog 1 (Drosophila)0.755
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.747
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.727
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 10.726
SNX9sorting nexin 90.725
S100A11S100 calcium binding protein A110.715
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.697
MPZL2myelin protein zero-like 20.690
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.664
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.663
ARPC3actin related protein 2/3 complex, subunit 3, 21kDa0.660
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.654
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.654
CAPZBcapping protein (actin filament) muscle Z-line, beta0.651
WIPF1WAS/WASL interacting protein family, member 10.647
S100BS100 calcium binding protein B0.635
DAAM1dishevelled associated activator of morphogenesis 10.631
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.630
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.627
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.616
HCKhemopoietic cell kinase0.612
CTTNcortactin0.601
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.600
CAPNS1calpain, small subunit 10.594
FN1fibronectin 10.593
ARFGEF2ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)0.592
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.588
PALLDpalladin, cytoskeletal associated protein0.579
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.573
DSPdesmoplakin0.571
PDCD6IPprogrammed cell death 6 interacting protein0.568
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.562
ARPC1Bactin related protein 2/3 complex, subunit 1B, 41kDa0.561
LIN7Blin-7 homolog B (C. elegans)0.547
NTRK2neurotrophic tyrosine kinase, receptor, type 20.524
PDLIM7PDZ and LIM domain 7 (enigma)0.509
ACTN1actinin, alpha 10.508
SPRY4sprouty homolog 4 (Drosophila)0.505
LMNAlamin A/C0.491
DSG2desmoglein 20.491
WASF1WAS protein family, member 10.491
TPM4tropomyosin 40.488
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.472
ROCK1Rho-associated, coiled-coil containing protein kinase 10.461
SCHIP1schwannomin interacting protein 10.454
DNM2dynamin 20.453
PRKCAprotein kinase C, alpha0.440
SPTBspectrin, beta, erythrocytic0.438
S100A4S100 calcium binding protein A40.435
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ina-1Protein INA-10.400
sem-5Protein SEM-50.217
cdc-42Protein CDC-420.213
unc-60Protein UNC-600.208
CELE_Y45F10B.13Protein Y45F10B.130.206
inx-13Protein INX-130.164
tni-1Protein TNI-10.153
sorb-1Protein SORB-10.151
csn-5Protein CSN-50.151
lat-1Protein LAT-10.139
cap-1Protein CAP-10.134
unc-45Protein UNC-450.126
unc-15Protein UNC-150.110
R11A8.7Protein R11A8.70.108
sma-1Protein SMA-10.103
myo-3Protein MYO-30.102
rab-5Protein RAB-50.102
atf-7Protein ATF-70.092
CELE_W05H12.1Protein W05H12.10.086
mep-1Protein MEP-10.084
sax-3Protein SAX-30.080
afd-1Protein AFD-10.080
kin-4Protein KIN-40.079
mpk-1Protein MPK-10.078
T28B11.1Protein T28B11.10.078
gsp-1Protein GSP-10.078
goa-1Protein GOA-10.072
unc-16Protein UNC-160.070
twk-18Protein TWK-180.069
pat-12Protein PAT-120.067
alp-1Protein ALP-10.066
mnp-1Protein MNP-10.064
mig-2Protein MIG-20.062
tag-343Protein TAG-3430.062
unc-68Protein UNC-680.062
R90.1Protein R90.10.061
lin-24Protein LIN-240.061
lin-7Protein LIN-70.060
egl-44Protein EGL-440.059
F10E9.3Protein F10E9.30.058
CELE_Y67A10A.9Protein Y67A10A.90.056
CELE_B0238.10Protein B0238.100.055
eps-8Protein EPS-80.055
T21B6.3Protein T21B6.30.053
xpo-1Protein XPO-10.053
abts-1Protein ABTS-10.052
egl-27Protein EGL-270.052
unc-9Protein UNC-90.052
alx-1Protein ALX-10.051
gcs-1Protein GCS-10.049
klp-3Protein KLP-30.049
gei-18Protein GEI-180.046
egl-46Protein EGL-460.046
tmc-2Protein TMC-20.046
kgb-1Protein KGB-10.044
hipr-1Protein HIPR-10.043
unc-112Protein UNC-1120.043
hbl-1Protein HBL-10.043
stip-1Protein STIP-10.042
F21C10.7Protein F21C10.70.042
ost-1Protein OST-10.041
csnk-1Protein CSNK-10.040
CELE_T13H5.1Protein T13H5.10.039
unc-41Protein UNC-410.039
W06F12.2Protein W06F12.20.038
let-60Protein LET-600.037
cam-1Protein CAM-10.037
zoo-1Protein ZOO-10.036
praf-3Protein PRAF-30.036
pry-1Protein PRY-10.036
C54E4.2Protein C54E4.20.035
par-6Protein PAR-60.035
acy-1Protein ACY-10.035
dlg-1Protein DLG-10.034
ced-10Protein CED-100.034
mek-2Protein MEK-20.034
H43E16.1Protein H43E16.10.034
par-1Protein PAR-10.034
magi-1Protein MAGI-10.033
mec-7Protein MEC-70.033
T16G1.9Protein T16G1.90.033
trim-9Protein TRIM-90.033
M02D8.1Protein M02D8.10.033
hmp-1Protein HMP-10.033
C27H2.2Protein C27H2.20.033
ttm-4Protein TTM-40.032
unc-32Protein UNC-320.032
atn-1Protein ATN-10.031
pha-4Protein PHA-40.031
let-2Protein LET-20.030
T14B1.1Protein T14B1.10.030
C06G1.5Protein C06G1.50.029
ztf-22Protein ZTF-220.029
unc-116Protein UNC-1160.029
F28E10.1Protein F28E10.10.029
mig-5Protein MIG-50.029
B0001.3Protein B0001.30.028
CELE_T04H1.2Protein T04H1.20.028
R148.3Protein R148.30.028
T05G5.1Protein T05G5.10.028
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
smyd1bSET and MYND domain containing 1b0.732
myhz2myosin, heavy polypeptide 2, fast muscle specific0.620
cotl1coactosin-like 1 (Dictyostelium)0.502
itgb1b.2integrin, beta 1b.20.233
msnamoesin a0.180
gna12guanine nucleotide binding protein (G protein) alpha 120.156
sept2septin 20.139
tpm4tropomyosin 40.074
pak2ap21 (CDKN1A)-activated kinase 2a0.073
klf2bKruppel-like factor 2b0.071
kdrlkinase insert domain receptor like0.071
itgb3bintegrin beta 3b0.067
snx12sorting nexin 120.065
gnai2lguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like0.064
dsc2ldesmocollin 2 like0.063
ighmimmunoglobulin heavy constant mu and immunoglobulin heavy constant mu0.060
tpm3tropomyosin 30.059
llgl2lethal giant larvae homolog 2 (Drosophila)0.057
bactin1bactin10.055
arhgdiaRho GDP dissociation inhibitor (GDI) alpha0.052
arpc5bactin related protein 2/3 complex, subunit 5B0.047
mfn2mitofusin 20.046
perpPERP, TP53 apoptosis effector0.046
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.045
tnnc1btroponin C type 1b (slow)0.044
lcp1lymphocyte cytosolic plastin 10.043
ef1aelongation factor 1-alpha0.041
csrp1acysteine and glycine-rich protein 1a0.040
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.038
myogmyogenin0.038
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.036
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.036
myl9lmyosin, light polypeptide 9, like0.036
LOC100003330melanocortin-2 receptor accessory protein 2-like0.036
wt1bwilms tumor 1b0.035
LOC557072caspase recruitment domain-containing protein 11-like0.032
krt8keratin 80.032
si:ch211-212m21.5si:ch211-212m21.50.031
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.030
acvr1bactivin A receptor, type IB0.029
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.029
pycardPYD and CARD domain containing0.029
lyzlysozyme0.028
prickle1aprickle-like 1 (Drosophila) a0.028
scinlascinderin like a0.028
si:ch73-60e21.1si:ch73-60e21.10.027
slit3slit (Drosophila) homolog 30.027
atp1a2aATPase, Na+/K+ transporting, alpha 2a polypeptide0.027
tp63tumor protein p630.026
nrp1aneuropilin 1a0.026
fli1bfriend leukemia integration 1b0.026
fabp11afatty acid binding protein 11a0.026
icnictacalcin0.026
tal1T-cell acute lymphocytic leukemia 10.025
mylz2myosin, light polypeptide 2, skeletal muscle0.024
spns2spinster homolog 2 (Drosophila)0.024
adrb2aadrenergic receptor, beta 2a0.024
itgb1aintegrin, beta 1a0.023
jupjunction plakoglobin0.023
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.023
csf3rcolony stimulating factor 3 receptor (granulocyte)0.022
tuba8l3tubulin, alpha 8 like 30.022
cyt1type I cytokeratin, enveloping layer0.022
gna11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)0.021
casz1castor zinc finger 10.021
krt4keratin 40.021
lims1LIM and senescent cell antigen-like domains 10.021
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.021
zgc:153867zgc:1538670.021
me2malic enzyme 2, NAD(+)-dependent, mitochondrial0.021
pvrl1bpoliovirus receptor-related 1b0.021
fam3cfamily with sequence similarity 3, member C0.021
atp2a2aATPase, Ca++ transporting, cardiac muscle, slow twitch 2a0.020
pdlim1PDZ and LIM domain 1 (elfin)0.020
epb4.1l4erythrocyte protein band 4.1-like 40.020
prdm14PR domain containing 140.020
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.020
itgb1bintegrin, beta 1b0.019
ptger2aprostaglandin E receptor 2a (subtype EP2)0.019
mybpc3myosin binding protein C, cardiac0.019
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.019
gng3guanine nucleotide binding protein (G protein), gamma 30.019
krt5keratin 50.019
irf6interferon regulatory factor 60.018
zgc:100942zgc:1009420.018
pvalb8parvalbumin 80.018
atp1b2bATPase, Na+/K+ transporting, beta 2b polypeptide0.018
ctnnb1catenin (cadherin-associated protein), beta 10.018
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.017
bnc2basonuclin 20.017
mmp9matrix metalloproteinase 90.017
acta1bactin, alpha 1b, skeletal muscle0.017
igfbp3insulin-like growth factor binding protein 30.016
gnazguanine nucleotide binding protein (G protein), alpha z polypeptide0.016
cmlc1cardiac myosin light chain-10.016
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.016
atp1a3aATPase, Na+/K+ transporting, alpha 3a polypeptide0.016
vegfaavascular endothelial growth factor Aa0.016
ucp2uncoupling protein 20.016
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.016
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rho1CG8416 gene product from transcript CG8416-RB0.963
chicchickadee0.934
Akt1CG4006 gene product from transcript CG4006-RA0.879
Rac1CG2248 gene product from transcript CG2248-RA0.877
Rab11Rab-protein 110.877
uspultraspiracle0.826
cpbcapping protein beta0.795
cindrCIN85 and CD2AP orthologue0.775
msnmisshapen0.716
katanin-60katanin 600.657
zipzipper0.657
Arc-p34CG10954 gene product from transcript CG10954-RA0.644
Cdc42CG12530 gene product from transcript CG12530-RA0.626
aopanterior open0.609
trctricornered0.599
Vrp1Verprolin 10.566
flwflapwing0.550
WASpCG1520 gene product from transcript CG1520-RA0.484
CadNCadherin-N0.477
shotshort stop0.474
par-1CG8201 gene product from transcript CG8201-RA0.420
mbcmyoblast city0.409
Src64BSrc oncogene at 64B0.399
Sra-1specifically Rac1-associated protein 10.397
bskbasket0.396
CortactinCG3637 gene product from transcript CG3637-RA0.369
roboroundabout0.322
rokRho-kinase0.320
slssallimus0.315
par-6CG5884 gene product from transcript CG5884-RA0.306
pblpebble0.300
bazbazooka0.298
RalaRas-related protein0.287
sqhspaghetti squash0.269
pod1CG4532 gene product from transcript CG4532-RF0.253
hephemipterous0.232
enaenabled0.227
Arp66BActin-related protein 66B0.224
S6kRPS6-p70-protein kinase0.223
drprdraper0.214
htlheartless0.210
ovoCG6824 gene product from transcript CG6824-RE0.207
Dcr-2Dicer-20.205
HemHEM-protein0.205
mysmyospheroid0.205
Arp14DActin-related protein 14D0.202
CG10641CG10641 gene product from transcript CG10641-RA0.201
trioCG18214 gene product from transcript CG18214-RA0.200
tumtumbleweed0.189
neurneuralized0.184
dshdishevelled0.180
shnschnurri0.177
Pak3CG14895 gene product from transcript CG14895-RA0.175
AblAbl tyrosine kinase0.169
tsrtwinstar0.166
SosSon of sevenless0.166
ctaconcertina0.165
p120ctnAdherens junction protein p1200.163
panpangolin0.157
alpha-Catalpha Catenin0.154
armarmadillo0.143
Act57BActin 57B0.142
spispitz0.141
Cip4CG15015 gene product from transcript CG15015-RA0.128
spirspire0.127
rstroughest0.126
LaspCG3849 gene product from transcript CG3849-RB0.125
EphEph receptor tyrosine kinase0.125
chercheerio0.120
flrflare0.119
bifbifocal0.118
PakPAK-kinase0.114
Actnalpha actinin0.114
ShcSHC-adaptor protein0.112
stcksteamer duck0.110
kstkarst0.109
Pi3K92ECG4141 gene product from transcript CG4141-RB0.108
DadDaughters against dpp0.107
CG6051CG6051 gene product from transcript CG6051-RB0.106
tutlturtle0.104
howheld out wings0.102
Dhc64CDynein heavy chain 64C0.101
Zasp52Z band alternatively spliced PDZ-motif protein 520.099
diadiaphanous0.096
JraJun-related antigen0.095
coracoracle0.093
rheaCG6831 gene product from transcript CG6831-RA0.092
Dap160Dynamin associated protein 1600.090
eglegalitarian0.090
jarjaguar0.090
MicalMolecule interacting with CasL0.090
myoglianinCG1838 gene product from transcript CG1838-RD0.088
cpacapping protein alpha0.088
PvrPDGF- and VEGF-receptor related0.087
dlg1discs large 10.087
CG11299CG11299 gene product from transcript CG11299-RA0.087
Arf51FADP ribosylation factor 51F0.086
Rab5Rab-protein 50.083
CG32528CG32528 gene product from transcript CG32528-RA0.081
cnocanoe0.080
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.999
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.984
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.980
Rac1RAS-related C3 botulinum substrate 10.977
Ldb3LIM domain binding 30.970
Efnb2ephrin B20.967
Dab1disabled homolog 1 (Drosophila)0.962
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.954
Scn5asodium channel, voltage-gated, type V, alpha0.947
Pick1protein interacting with C kinase 10.938
Actr3ARP3 actin-related protein 3 homolog (yeast)0.929
SrcRous sarcoma oncogene0.920
Dvl2dishevelled 2, dsh homolog (Drosophila)0.911
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.885
Cttncortactin0.870
Akt1thymoma viral proto-oncogene 10.870
CblCasitas B-lineage lymphoma0.868
Dok1docking protein 10.863
Plcg1phospholipase C, gamma 10.847
Dlg4discs, large homolog 4 (Drosophila)0.840
Arpc4actin related protein 2/3 complex, subunit 40.836
Ptenphosphatase and tensin homolog0.829
Wdr1WD repeat domain 10.827
Apcadenomatosis polyposis coli0.826
Ptk2PTK2 protein tyrosine kinase 20.800
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.774
Gsk3bglycogen synthase kinase 3 beta0.770
Capzbcapping protein (actin filament) muscle Z-line, beta0.763
Nedd4lneural precursor cell expressed, developmentally down-regulated gene 4-like0.755
Abi1abl-interactor 10.748
Grb2growth factor receptor bound protein 20.741
WasWiskott-Aldrich syndrome homolog (human)0.723
Pxnpaxillin0.720
Dnm1dynamin 10.714
Csf1colony stimulating factor 1 (macrophage)0.659
Nos3nitric oxide synthase 3, endothelial cell0.650
Lrrk2leucine-rich repeat kinase 20.641
Mpdzmultiple PDZ domain protein0.617
Ephb2Eph receptor B20.615
Gja1gap junction protein, alpha 10.612
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.575
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.569
Tjp1tight junction protein 10.550
Fzd2frizzled homolog 2 (Drosophila)0.539
Itgb3integrin beta 30.538
Ctnna1catenin (cadherin associated protein), alpha 10.529
Ryr2ryanodine receptor 2, cardiac0.513
Vangl1vang-like 1 (van gogh, Drosophila)0.501
Clic1chloride intracellular channel 10.495
Gab1growth factor receptor bound protein 2-associated protein 10.494
Inpp5dinositol polyphosphate-5-phosphatase D0.473
Cdh2cadherin 20.469
Spnb1spectrin beta 10.465
Actbactin, beta0.464
Tgfb2transforming growth factor, beta 20.450
Prkceprotein kinase C, epsilon0.447
Myo1cmyosin IC0.446
Cd44CD44 antigen0.443
Epha4Eph receptor A40.438
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.436
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.433
Bcar1breast cancer anti-estrogen resistance 10.429
Emp2epithelial membrane protein 20.426
Nfe2l3nuclear factor, erythroid derived 2, like 30.425
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.421
Laptm5lysosomal-associated protein transmembrane 50.416
Ptpreprotein tyrosine phosphatase, receptor type, E0.411
Kitlkit ligand0.409
Vangl2vang-like 2 (van gogh, Drosophila)0.407
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.402
Hcls1hematopoietic cell specific Lyn substrate 10.398
Prkcbprotein kinase C, beta0.398
Desdesmin0.397
Rbbp7retinoblastoma binding protein 70.395
Tpm4tropomyosin 40.394
Wnt6wingless-related MMTV integration site 60.389
Ephb3Eph receptor B30.388
Arhgap1Rho GTPase activating protein 10.382
Plcd1phospholipase C, delta 10.381
Efsembryonal Fyn-associated substrate0.376
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.375
Mtormechanistic target of rapamycin (serine/threonine kinase)0.374
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.372
Fzd6frizzled homolog 6 (Drosophila)0.367
Mapkap1mitogen-activated protein kinase associated protein 10.359
Ppfia4protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 40.356
Zap70zeta-chain (TCR) associated protein kinase0.354
Jupjunction plakoglobin0.352
Trp53transformation related protein 530.351
Csrp1cysteine and glycine-rich protein 10.345
Kalrnkalirin, RhoGEF kinase0.342
Scn1asodium channel, voltage-gated, type I, alpha0.340
Actr2ARP2 actin-related protein 2 homolog (yeast)0.337
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.336
Irs1insulin receptor substrate 10.334
Emid2EMI domain containing 20.334
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.331
Dlg1discs, large homolog 1 (Drosophila)0.325
Fermt3fermitin family homolog 3 (Drosophila)0.321
Actn2actinin alpha 20.321
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Efhd2EF-hand domain family, member D20.671
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.578
Pfn1profilin 10.444
Taglntransgelin0.308
Rab1bRAB1B, member RAS oncogene family0.270
Arpc2actin related protein 2/3 complex, subunit 20.224
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.212
Arpc1bactin related protein 2/3 complex, subunit 1B0.176
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.169
Sirpasignal-regulatory protein alpha0.157
Srisorcin0.149
Myl9myosin, light chain 9, regulatory0.133
Acta2smooth muscle alpha-actin0.130
Gja1gap junction protein, alpha 10.118
Akt2v-akt murine thymoma viral oncogene homolog 20.111
Syt8synaptotagmin VIII0.104
Myh9myosin, heavy chain 9, non-muscle0.100
Dlgap1discs, large (Drosophila) homolog-associated protein 10.096
Laptm5lysosomal protein transmembrane 50.093
Tpm3tropomyosin 3, gamma0.088
Spt1salivary protein 10.087
Wdr1WD repeat domain 10.087
Gad2glutamate decarboxylase 20.087
Coro1acoronin, actin binding protein 1A0.082
Lcp1lymphocyte cytosolic protein 10.082
Rap1bRAP1B, member of RAS oncogene family0.082
Bcl2l1Bcl2-like 10.079
Cyth1cytohesin 10.079
Cav1caveolin 1, caveolae protein0.078
Glp1rglucagon-like peptide 1 receptor0.078
Gria3glutamate receptor, ionotrophic, AMPA 30.077
Tpm2tropomyosin 2, beta0.076
Myh6myosin, heavy chain 6, cardiac muscle, alpha0.075
Hk1hexokinase 10.074
Fkbp1aFK506 binding protein 1a0.074
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.072
Nedd4neural precursor cell expressed, developmentally down-regulated 40.066
Sh3bgrl3SH3 domain binding glutamic acid-rich protein-like 30.066
Casq2calsequestrin 2 (cardiac muscle)0.064
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.062
Tmpothymopoietin0.062
Dlg3discs, large homolog 3 (Drosophila)0.061
Anxa2annexin A20.061
Cttncortactin0.061
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.061
Rims1regulating synaptic membrane exocytosis 10.061
Shank2SH3 and multiple ankyrin repeat domains 20.060
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.060
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.059
Ryr2ryanodine receptor 2, cardiac0.058
LOC100362824caveolin 2-like0.058
Cdc42cell division cycle 42 (GTP binding protein)0.057
Mapre1microtubule-associated protein, RP/EB family, member 10.057
Dgkgdiacylglycerol kinase, gamma0.055
Trib1tribbles homolog 1 (Drosophila)0.053
Grid2glutamate receptor, ionotropic, delta 20.052
Ptpn6protein tyrosine phosphatase, non-receptor type 60.051
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.050
Tubb5tubulin, beta 50.049
Ap2m1adaptor-related protein complex 2, mu 1 subunit0.049
Actr3ARP3 actin-related protein 3 homolog (yeast)0.048
Cd38CD38 molecule0.048
Grip1glutamate receptor interacting protein 10.048
Dstndestrin0.048
Ucp3uncoupling protein 3 (mitochondrial, proton carrier)0.048
Cckarcholecystokinin A receptor0.047
Smad7SMAD family member 70.047
Lmnalamin A0.047
Asphaspartate-beta-hydroxylase0.047
Prg2proteoglycan 2, bone marrow0.047
Gria1glutamate receptor, ionotropic, AMPA 10.046
Tagln2transgelin 20.044
Taok1TAO kinase 10.044
Ptmaprothymosin alpha0.043
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.043
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.042
Oprk1opioid receptor, kappa 10.042
Eif4heukaryotic translation initiation factor 4H0.042
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.042
Gfra2GDNF family receptor alpha 20.042
Csrp1cysteine and glycine-rich protein 10.041
Rhoaras homolog gene family, member A0.041
Freqfrequenin homolog (Drosophila)0.041
Kalrnkalirin, RhoGEF kinase0.041
Hand2heart and neural crest derivatives expressed 20.040
Prkcdprotein kinase C, delta0.040
Myl1myosin, light chain 10.040
Vegfavascular endothelial growth factor A0.040
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.039
Fgf7fibroblast growth factor 70.039
Gng7guanine nucleotide binding protein (G protein), gamma 70.039
Ptprcprotein tyrosine phosphatase, receptor type, C0.039
Map3k1mitogen activated protein kinase kinase kinase 10.039
Capn9calpain 90.039
Gna12guanine nucleotide binding protein (G protein) alpha 120.039
Plauplasminogen activator, urokinase0.038
Epn1Epsin 10.038
Nos3nitric oxide synthase 3, endothelial cell0.038
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.038
Map1amicrotubule-associated protein 1A0.037
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ABP1Abp1p0.986
MYO5Myo5p0.985
ACT1Act1p0.848
CDC24Cdc24p0.829
SRV2Srv2p0.780
SSK2Ssk2p0.714
RHO1Rho1p0.682
BNI1Bni1p0.667
CAP2Cap2p0.638
ARC15Arc15p0.637
BEM3Bem3p0.615
LSB1Lsb1p0.558
BEM1Bem1p0.455
SPA2Spa2p0.454
SAC6Sac6p0.421
ARC35Arc35p0.333
CDC42Cdc42p0.300
ARP3Arp3p0.293
SLA2Sla2p0.291
BBC1Bbc1p0.287
ARP2Arp2p0.262
CYK3Cyk3p0.252
ARC40Arc40p0.245
LAS17Las17p0.228
PFY1Pfy1p0.228
RVS167Rvs167p0.214
BEM2Bem2p0.176
BUD6Bud6p0.166
ARC19Arc19p0.162
TOR1Tor1p0.153
BOI1Boi1p0.152
TPM1Tpm1p0.146
RDI1Rdi1p0.141
TWF1Twf1p0.140
GIC1Gic1p0.139
ARC18Arc18p0.134
HOF1Hof1p0.134
FAR1Far1p0.126
ROM2Rom2p0.123
NBP2Nbp2p0.122
APP1App1p0.105
AVO1Avo1p0.094
CAP1Cap1p0.089
BEM4Bem4p0.089
PBS2Pbs2p0.073
GIP4Gip4p0.068
BZZ1Bzz1p0.068
SSK1Ssk1p0.068
AIP1Aip1p0.062
FUS1Fus1p0.058
DCP2Dcp2p0.058
GYL1Gyl1p0.057
BOI2Boi2p0.055
PTC1Ptc1p0.054
ZDS1Zds1p0.053
KEL1Kel1p0.050
PEX13Pex13p0.050
PPH21Pph21p0.047
RSR1Rsr1p0.045
MLC1Mlc1p0.043
AIM7Aim7p0.042
SCP1Scp1p0.042
MOB2Mob2p0.042
LSB6Lsb6p0.042
PIN3Pin3p0.038
UGO1Ugo1p0.036
MKK1Mkk1p0.036
STE12Ste12p0.034
MDM32Mdm32p0.034
NUM1Num1p0.034
HYM1Hym1p0.033
STE7Ste7p0.030
BUD14Bud14p0.029
MYO4Myo4p0.028
PRS2Prs2p0.028
MER1Mer1p0.027
BCK1Bck1p0.027
GYP1Gyp1p0.026
ENT3Ent3p0.026
SSK22Ssk22p0.026
TEF1Tef1p0.026
FUS2Fus2p0.025
EXO70Exo70p0.025
PPH3Pph3p0.025
KOG1Kog1p0.025
ACK1Ack1p0.024
RGD1Rgd1p0.024
YLR162Whypothetical protein0.024
COF1Cof1p0.024
YER134Chypothetical protein0.023
AIM21Aim21p0.023
TOM1Tom1p0.023
RIO2Rio2p0.023
CLA4Cla4p0.022
PEF1Pef1p0.022
IRA1Ira1p0.022
YPK1Ypk1p0.022
YPL014Whypothetical protein0.022
YNL058Chypothetical protein0.021
KIN3Kin3p0.021