The network for 'respiratory chain complex iv assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

respiratory chain complex iv assembly

The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CCDC56coiled-coil domain containing 560.552
SFXN4sideroflexin 40.273
C12orf62chromosome 12 open reading frame 620.163
MRPL46mitochondrial ribosomal protein L460.148
SLC25A11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.109
SURF1surfeit 10.058
NDUFC2NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa0.044
UQCR10ubiquinol-cytochrome c reductase, complex III subunit X0.036
NDUFAF1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 10.032
TMEM186transmembrane protein 1860.031
EIF2B3eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa0.031
NDUFB2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa0.029
COX1cytochrome c oxidase subunit I0.025
POP5processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)0.025
CMC1COX assembly mitochondrial protein homolog (S. cerevisiae)0.025
CHCHD4coiled-coil-helix-coiled-coil-helix domain containing 40.023
NDUFA8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa0.020
TMEM177transmembrane protein 1770.019
TACO1translational activator of mitochondrially encoded cytochrome c oxidase I0.018
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.018
KAT2AK(lysine) acetyltransferase 2A0.016
NFS1NFS1 nitrogen fixation 1 homolog (S. cerevisiae)0.015
C3orf1chromosome 3 open reading frame 10.015
METTL17methyltransferase like 170.013
PET112LPET112-like (yeast)0.012
MRPL24mitochondrial ribosomal protein L240.012
ATP5G1ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)0.011
NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa0.011
MRPS33mitochondrial ribosomal protein S330.011
TIMM8Btranslocase of inner mitochondrial membrane 8 homolog B (yeast)0.010
COQ3coenzyme Q3 homolog, methyltransferase (S. cerevisiae)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
COA4Coa4p0.701
COX1Cox1p0.628
COX14Cox14p0.514
PET117Pet117p0.351
PET191Pet191p0.345
COX23Cox23p0.290
MRPL51Mrpl51p0.260
CBP6Cbp6p0.250
CAT5Cat5p0.152
COX17Cox17p0.146
AIM31Aim31p0.126
YMR244C-Ahypothetical protein0.126
DID4Did4p0.122
COX4Cox4p0.114
COX7Cox7p0.112
COX13Cox13p0.104
CMC1Cmc1p0.087
SHY1Shy1p0.070
MRPL50Mrpl50p0.067
ACN9Acn9p0.064
HSP10Hsp10p0.060
AIM43Aim43p0.056
SCO1Sco1p0.055
FMP10Fmp10p0.046
MZM1Mzm1p0.045
ECM19Ecm19p0.044
MDJ1Mdj1p0.044
COX11Cox11p0.042
AIM11Aim11p0.042
ATP6Atp6p0.041
COX10Cox10p0.041
YJL055Whypothetical protein0.040
PET112Pet112p0.040
CBP4Cbp4p0.039
SRD1Srd1p0.039
TIM9Tim9p0.038
CTR3Ctr3p0.037
LEU2Leu2p0.036
YIA6Yia6p0.036
YLR162Whypothetical protein0.036
QCR6Qcr6p0.036
YLR264C-Ahypothetical protein0.035
CUP1-1Cup1-1p0.034
YGR021Whypothetical protein0.034
CBT1Cbt1p0.034
IMP1Imp1p0.032
MIC14Mic14p0.032
GUF1Guf1p0.032
NCE101Nce101p0.032
YOL038C-Ahypothetical protein0.031
ARP10Arp10p0.031
MER1Mer1p0.030
ADE17Ade17p0.029
RRN5Rrn5p0.029
RAS2Ras2p0.029
SPL2Spl2p0.029
AIM10Aim10p0.029
YLR042Chypothetical protein0.029
REE1Ree1p0.029
HXT3Hxt3p0.028
SFT1Sft1p0.028
AUA1Aua1p0.028
ICS2Ics2p0.027
YAR068Whypothetical protein0.027
AQY2Aqy2p0.027
BSC1Bsc1p0.027
MRPL33Mrpl33p0.026
CYC7Cyc7p0.026
CYT2Cyt2p0.026
FMT1Fmt1p0.026
HPF1Hpf1p0.026
YPR157Whypothetical protein0.026
CUE4Cue4p0.024
REX2Rex2p0.024
YKR075Chypothetical protein0.024
ZPS1Zps1p0.024
COX15Cox15p0.023
OPT2Opt2p0.023
YBR013Chypothetical protein0.023
COX2Cox2p0.023
UBC1Ubc1p0.023
YPR153Whypothetical protein0.022
MF(ALPHA)2Mf(alpha)2p0.022
MRPL28Mrpl28p0.022
IZH4Izh4p0.022
YOL013W-Ahypothetical protein0.022
DIC1Dic1p0.022
YLL053Chypothetical protein0.022
COX8Cox8p0.021
PCL9Pcl9p0.021
YJR120Whypothetical protein0.021
AIM23Aim23p0.021
YDR115Whypothetical protein0.021
CPD1Cpd1p0.021
YAR066Whypothetical protein0.021
YLR040Chypothetical protein0.021
ADH2Adh2p0.020
SRX1Srx1p0.020
GYL1Gyl1p0.020
EMI5Emi5p0.020