The network for 'interferon gamma production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

interferon gamma production

The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.

NameDescriptionProbabilityFunc Analog Organism
HCKhemopoietic cell kinase0.956
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.939
HLA-Amajor histocompatibility complex, class I, A0.937
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.918
HLA-Bmajor histocompatibility complex, class I, B0.890
B2Mbeta-2-microglobulin0.814
LCKlymphocyte-specific protein tyrosine kinase0.792
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.785
HLA-Gmajor histocompatibility complex, class I, G0.777
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.776
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.747
HLA-Fmajor histocompatibility complex, class I, F0.741
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.717
TRAF1TNF receptor-associated factor 10.716
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.698
BTN3A2butyrophilin, subfamily 3, member A20.693
SYKspleen tyrosine kinase0.683
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.679
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.668
BTN3A3butyrophilin, subfamily 3, member A30.649
SPRR2Asmall proline-rich protein 2A0.629
IL1R1interleukin 1 receptor, type I0.580
NLRC4NLR family, CARD domain containing 40.563
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.547
CD84CD84 molecule0.539
CASP8caspase 8, apoptosis-related cysteine peptidase0.500
EGFRepidermal growth factor receptor0.450
CCR5chemokine (C-C motif) receptor 50.448
HLA-Cmajor histocompatibility complex, class I, C0.433
CCL5chemokine (C-C motif) ligand 50.426
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.394
BIRC3baculoviral IAP repeat containing 30.383
CD86CD86 molecule0.361
BTN3A1butyrophilin, subfamily 3, member A10.351
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.303
GAS6growth arrest-specific 60.293
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.283
FASFas (TNF receptor superfamily, member 6)0.277
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.276
HLA-Emajor histocompatibility complex, class I, E0.272
CD80CD80 molecule0.270
RXRAretinoid X receptor, alpha0.252
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.251
HLA-DRB5major histocompatibility complex, class II, DR beta 50.245
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.230
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.223
CXCL9chemokine (C-X-C motif) ligand 90.219
CCR7chemokine (C-C motif) receptor 70.213
FASLGFas ligand (TNF superfamily, member 6)0.207
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.192
STAT4signal transducer and activator of transcription 40.177
CCR1chemokine (C-C motif) receptor 10.165
DDIT3DNA-damage-inducible transcript 30.164
FYNFYN oncogene related to SRC, FGR, YES0.161
IL1Binterleukin 1, beta0.158
MYD88myeloid differentiation primary response gene (88)0.146
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.143
PILRApaired immunoglobin-like type 2 receptor alpha0.141
CCL8chemokine (C-C motif) ligand 80.140
NOD2nucleotide-binding oligomerization domain containing 20.138
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.137
GRB2growth factor receptor-bound protein 20.134
GRB7growth factor receptor-bound protein 70.134
IL6interleukin 6 (interferon, beta 2)0.129
CCL4chemokine (C-C motif) ligand 40.125
AXLAXL receptor tyrosine kinase0.117
IL10interleukin 100.112
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.111
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.105
SP110SP110 nuclear body protein0.104
MEFVMediterranean fever0.102
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.096
BLNKB-cell linker0.095
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.095
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.093
CXCL2chemokine (C-X-C motif) ligand 20.092
NCK1NCK adaptor protein 10.090
TICAM2toll-like receptor adaptor molecule 20.087
IL23Ainterleukin 23, alpha subunit p190.084
CD247CD247 molecule0.082
HLA-DRB4major histocompatibility complex, class II, DR beta 40.081
IL10RAinterleukin 10 receptor, alpha0.081
TNFtumor necrosis factor0.080
IL1R2interleukin 1 receptor, type II0.079
CCL2chemokine (C-C motif) ligand 20.077
CASP10caspase 10, apoptosis-related cysteine peptidase0.077
CTLA4cytotoxic T-lymphocyte-associated protein 40.076
IL1RNinterleukin 1 receptor antagonist0.076
CYBBcytochrome b-245, beta polypeptide0.070
MED25mediator complex subunit 250.069
IRF1interferon regulatory factor 10.069
ESR1estrogen receptor 10.068
RIN1Ras and Rab interactor 10.068
CCL22chemokine (C-C motif) ligand 220.067
IFITM1interferon induced transmembrane protein 1 (9-27)0.066
CCL7chemokine (C-C motif) ligand 70.066
PHYHIPLphytanoyl-CoA 2-hydroxylase interacting protein-like0.066
ICAM1intercellular adhesion molecule 10.064
RARAretinoic acid receptor, alpha0.064
CTBP2C-terminal binding protein 20.063
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Map3k14mitogen-activated protein kinase kinase kinase 140.961
Tnftumor necrosis factor0.930
Klrk1killer cell lectin-like receptor subfamily K, member 10.866
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.824
Cd40CD40 antigen0.815
Icosinducible T-cell co-stimulator0.813
Tlr4toll-like receptor 40.806
Pax2paired box gene 20.702
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.693
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.676
Ifnginterferon gamma0.672
Klrd1killer cell lectin-like receptor, subfamily D, member 10.651
Ikzf1IKAROS family zinc finger 10.634
Socs1suppressor of cytokine signaling 10.561
Slamf1signaling lymphocytic activation molecule family member 10.545
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.515
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.484
Gzmkgranzyme K0.483
Il2rbinterleukin 2 receptor, beta chain0.478
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.475
Cd44CD44 antigen0.474
BtkBruton agammaglobulinemia tyrosine kinase0.461
Fgf8fibroblast growth factor 80.456
Emx2empty spiracles homolog 2 (Drosophila)0.450
Il18rapinterleukin 18 receptor accessory protein0.448
Il1rl1interleukin 1 receptor-like 10.424
Pitx1paired-like homeodomain transcription factor 10.421
Ccr7chemokine (C-C motif) receptor 70.416
Casp4caspase 4, apoptosis-related cysteine peptidase0.414
Nr5a1nuclear receptor subfamily 5, group A, member 10.413
Gzmbgranzyme B0.405
Klra9killer cell lectin-like receptor subfamily A, member 90.400
Il27rainterleukin 27 receptor, alpha0.398
FaslFas ligand (TNF superfamily, member 6)0.396
Sykbspleen tyrosine kinase0.377
Relreticuloendotheliosis oncogene0.371
Casp1caspase 10.367
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.367
Myd88myeloid differentiation primary response gene 880.364
Gzmagranzyme A0.364
H2-Q7histocompatibility 2, Q region locus 70.364
Ccr2chemokine (C-C motif) receptor 20.359
Cd86CD86 antigen0.357
Latlinker for activation of T cells0.328
ItkIL2-inducible T-cell kinase0.317
Ccl4chemokine (C-C motif) ligand 40.310
Ccl5chemokine (C-C motif) ligand 50.307
FasFas (TNF receptor superfamily member 6)0.306
Prdm1PR domain containing 1, with ZNF domain0.302
Tbx3T-box 30.298
Tnfaip3tumor necrosis factor, alpha-induced protein 30.294
Ncr1natural cytotoxicity triggering receptor 10.291
Cd28CD28 antigen0.289
Batfbasic leucine zipper transcription factor, ATF-like0.286
Itgalintegrin alpha L0.284
TcraT-cell receptor alpha chain0.279
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.275
Il18r1interleukin 18 receptor 10.274
Pou2af1POU domain, class 2, associating factor 10.271
Inpp5dinositol polyphosphate-5-phosphatase D0.259
Lhx3LIM homeobox protein 30.256
Map3k8mitogen-activated protein kinase kinase kinase 80.256
Gpr132G protein-coupled receptor 1320.256
Hoxa1homeobox A10.252
Il10interleukin 100.245
Il2rainterleukin 2 receptor, alpha chain0.239
B2mbeta-2 microglobulin0.239
Il10rainterleukin 10 receptor, alpha0.230
Cd160CD160 antigen0.225
Il2rginterleukin 2 receptor, gamma chain0.221
Cd5CD5 antigen0.220
Gimap7GTPase, IMAP family member 70.209
Ctswcathepsin W0.205
Ccr5chemokine (C-C motif) receptor 50.197
Sh2d2aSH2 domain protein 2A0.197
Xcl1chemokine (C motif) ligand 10.196
Scn5asodium channel, voltage-gated, type V, alpha0.186
Klrg1killer cell lectin-like receptor subfamily G, member 10.183
Pdcd1programmed cell death 10.181
Il4interleukin 40.180
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.174
Irf1interferon regulatory factor 10.171
Ifnar1interferon (alpha and beta) receptor 10.169
Pyhin1pyrin and HIN domain family, member 10.168
Sfpi1SFFV proviral integration 10.163
Wnt9awingless-type MMTV integration site 9A0.159
Cd80CD80 antigen0.159
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.158
Gata4GATA binding protein 40.156
Tnfsf10tumor necrosis factor (ligand) superfamily, member 100.156
Nkg7natural killer cell group 7 sequence0.156
Rargretinoic acid receptor, gamma0.152
Lifleukemia inhibitory factor0.152
Dkk1dickkopf homolog 1 (Xenopus laevis)0.150
Cxcl9chemokine (C-X-C motif) ligand 90.150
Cd180CD180 antigen0.150
Niacr1niacin receptor 10.150
Ltalymphotoxin A0.149
Nlrp3NLR family, pyrin domain containing 30.148
Ccrl2chemokine (C-C motif) receptor-like 20.147
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Klrd1killer cell lectin-like receptor, subfamily D, member 10.023
Sellselectin L0.022
Ccl4chemokine (C-C motif) ligand 40.022
Cxcl10chemokine (C-X-C motif) ligand 100.021
Il1binterleukin 1 beta0.020
Nkg7natural killer cell group 7 sequence0.019
Il6interleukin 60.019
RT1-A3RT1 class I, locus A30.019
Cd5Cd5 molecule0.017
Ccl5chemokine (C-C motif) ligand 50.017
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.017
Cd86CD86 molecule0.017
Ccl3chemokine (C-C motif) ligand 30.017
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.017
Vcanversican0.017
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.017
Ccl2chemokine (C-C motif) ligand 20.016
Prl8a7prolactin family 8, subfamily a, member 70.015
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.015
Hoxb7homeo box B70.015
Gja5gap junction protein, alpha 50.015
Ciitaclass II, major histocompatibility complex, transactivator0.015
Ccr2chemokine (C-C motif) receptor 20.014
Gimap4GTPase, IMAP family member 40.014
Il1ainterleukin 1 alpha0.014
Ncr1natural cytotoxicity triggering receptor 10.014
Cd44Cd44 molecule0.014
RT1-EC2RT1 class Ib, locus EC20.014
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.014
LOC100364500RT1 class I, locus CE11-like0.014
Gzmbgranzyme B0.014
LOC286992peptide HP (rs14)0.013
RT1-N3RT1 class Ib, locus N30.013
Gfi1growth factor independent 1 transcription repressor0.013
Pgcprogastricsin (pepsinogen C)0.013
Prl8a9prolactin family 8, subfamily a, member 90.013
Mcpt1mast cell protease 10.012
Il2rbinterleukin 2 receptor, beta0.012
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.012
Reg3gregenerating islet-derived 3 gamma0.012
Tnfrsf26tumor necrosis factor receptor superfamily, member 260.012
Il1rl1interleukin 1 receptor-like 10.012
TcrbT-cell receptor beta chain0.012
C3ar1complement component 3a receptor 10.012
Pde3aphosphodiesterase 3A, cGMP inhibited0.012
Slfn2schlafen 20.012
Gnrhrgonadotropin releasing hormone receptor0.012
Trhthyrotropin releasing hormone0.012
Spink5serine peptidase inhibitor, Kazal type 50.012
Cd22CD22 molecule0.012
Ifnginterferon gamma0.012
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.012
Pax8paired box 80.012
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.012
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.011
Defb1defensin beta 10.011
Pthparathyroid hormone0.011
RT1-HaRT1 class II, locus Ha0.011
Csf1colony stimulating factor 1 (macrophage)0.011
Sh2d1aSH2 domain protein 1A0.011
Nrg2neuregulin 20.011
Cd40CD40 molecule, TNF receptor superfamily member 50.011
Klra5killer cell lectin-like receptor, subfamily A, member 50.011
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.011
Sh3tc1SH3 domain and tetratricopeptide repeats 10.011
Neurl3neuralized homolog 3 (Drosophila)0.011
Il17finterleukin 17F0.011
Vom1r90vomeronasal 1 receptor 900.011
Ccr1chemokine (C-C motif) receptor 10.011
Casp12caspase 120.011
Spam1sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)0.011
Prlprolactin0.011
Cd2Cd2 molecule0.011
Ms4a7membrane-spanning 4-domains, subfamily A, member 70.010
Map3k8mitogen-activated protein kinase kinase kinase 80.010
Unc13dunc-13 homolog D (C. elegans)0.010
Casp1caspase 10.010
RatNP-3bdefensin RatNP-3 precursor0.010
Cd3gCD3 molecule, gamma0.010
Cycscytochrome c, somatic0.010
Vom2r27vomeronasal 2 receptor, 270.010
Leprleptin receptor0.010
Itgb7integrin, beta 70.010
Eporerythropoietin receptor0.010
Ednrbendothelin receptor type B0.010
Noxo1NADPH oxidase organizer 10.010
RGD1559588similar to cell surface receptor FDFACT0.010
Ifit3interferon-induced protein with tetratricopeptide repeats 30.010
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.010
Plaurplasminogen activator, urokinase receptor0.010
Nus1nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)0.010
Cd247Cd247 molecule0.010
Pla1aphospholipase A1 member A0.010
Tnftumor necrosis factor (TNF superfamily, member 2)0.010
LOC689770similar to osteoclast inhibitory lectin0.010
Fosl1fos-like antigen 10.010
Fabp2fatty acid binding protein 2, intestinal0.010
Calcacalcitonin-related polypeptide alpha0.010
Olr1469olfactory receptor Olr14690.010
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism