The network for 'telomere maintenance via recombination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

telomere maintenance via recombination

Any recombinational process that contributes to the maintenance of proper telomeric length.

NameDescriptionProbabilityFunc Analog Organism
RPA2replication protein A2, 32kDa0.954
WRNWerner syndrome, RecQ helicase-like0.938
FANCD2Fanconi anemia, complementation group D20.844
RAD51L3RAD51-like 3 (S. cerevisiae)0.824
BLMBloom syndrome, RecQ helicase-like0.816
C19orf39chromosome 19 open reading frame 390.787
H2AFXH2A histone family, member X0.736
NSMCE4Anon-SMC element 4 homolog A (S. cerevisiae)0.666
BRCA1breast cancer 1, early onset0.641
XRCC2X-ray repair complementing defective repair in Chinese hamster cells 20.593
RPA3replication protein A3, 14kDa0.576
RAD51L1RAD51-like 1 (S. cerevisiae)0.442
RAD18RAD18 homolog (S. cerevisiae)0.371
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.329
NBNnibrin0.309
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.289
RAD51CRAD51 homolog C (S. cerevisiae)0.175
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.171
OSGEPO-sialoglycoprotein endopeptidase0.114
RAD52RAD52 homolog (S. cerevisiae)0.095
YY1YY1 transcription factor0.093
UBR1ubiquitin protein ligase E3 component n-recognin 10.089
PALB2partner and localizer of BRCA20.079
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.075
LAGE3L antigen family, member 30.062
ACTR5ARP5 actin-related protein 5 homolog (yeast)0.057
RFC1replication factor C (activator 1) 1, 145kDa0.057
RPA1replication protein A1, 70kDa0.056
RAD50RAD50 homolog (S. cerevisiae)0.051
BRCA2breast cancer 2, early onset0.049
SMC6structural maintenance of chromosomes 60.049
INO80EINO80 complex subunit E0.045
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.038
MSH6mutS homolog 6 (E. coli)0.035
MSH3mutS homolog 3 (E. coli)0.033
TP53RKTP53 regulating kinase0.032
TTI1Tel2 interacting protein 1 homolog (S. pombe)0.030
TERF2telomeric repeat binding factor 20.026
ACTR8ARP8 actin-related protein 8 homolog (yeast)0.025
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.024
PMS1PMS1 postmeiotic segregation increased 1 (S. cerevisiae)0.023
MDC1mediator of DNA-damage checkpoint 10.023
CALCOCO2calcium binding and coiled-coil domain 20.023
H1F0H1 histone family, member 00.021
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.018
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.018
BRIP1BRCA1 interacting protein C-terminal helicase 10.017
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.017
SMC1Astructural maintenance of chromosomes 1A0.017
ATRXalpha thalassemia/mental retardation syndrome X-linked0.017
ZSWIM7zinc finger, SWIM-type containing 70.016
NDNL2necdin-like 20.016
MNAT1menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)0.016
RNF20ring finger protein 200.014
XPAxeroderma pigmentosum, complementation group A0.014
POLHpolymerase (DNA directed), eta0.013
RAD17RAD17 homolog (S. pombe)0.013
ATRataxia telangiectasia and Rad3 related0.013
INO80DINO80 complex subunit D0.012
NVLnuclear VCP-like0.012
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.012
HLTFhelicase-like transcription factor0.012
DDB1damage-specific DNA binding protein 1, 127kDa0.012
C14orf142chromosome 14 open reading frame 1420.011
MED31mediator complex subunit 310.011
DCLRE1ADNA cross-link repair 1A0.011
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.011
C7orf64chromosome 7 open reading frame 640.010
RBBP8retinoblastoma binding protein 80.010
YAF2YY1 associated factor 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mei-9meiotic 90.699
okrokra0.667
mus205mutagen-sensitive 2050.652
Brca2Breast cancer 2, early onset homolog0.641
mus101mutagen-sensitive 1010.588
mus301mutagen-sensitive 3010.266
mus308mutagen-sensitive 3080.258
mus201mutagen-sensitive 2010.224
mus304mutagen-sensitive 3040.213
nbsCG6754 gene product from transcript CG6754-RC0.207
spn-Bspindle B0.191
RecQ5homolog of RecQ0.152
lokloki0.116
DNApol-etaCG7143 gene product from transcript CG7143-RA0.107
hayhaywire0.092
rad50CG6339 gene product from transcript CG6339-RD0.079
RecQ4CG7487 gene product from transcript CG7487-RA0.079
ballballchen0.078
mus309mutagen-sensitive 3090.071
Orc5Origin recognition complex subunit 50.068
piepineapple eye0.052
spn-Aspindle A0.038
mre11meiotic recombination 110.038
Smc5CG32438 gene product from transcript CG32438-RE0.032
tefutelomere fusion0.023
IrbpInverted repeat-binding protein0.020
p53CG33336 gene product from transcript CG33336-RB0.020
mei-41meiotic 410.019
mus312mutagen-sensitive 3120.019
mus210mutagen-sensitive 2100.019
orboo18 RNA-binding protein0.016
Rev1CG12189 gene product from transcript CG12189-RA0.012
cuffcutoff0.012
spn-Dspindle D0.011
PHDPPutative homeodomain protein0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
PCC1Pcc1p0.982
EST2Est2p0.946
RFA1Rfa1p0.901
INO80Ino80p0.872
RFA2Rfa2p0.833
SMC6Smc6p0.832
KAE1Kae1p0.824
CGI121Cgi121p0.762
YRF1-5Yrf1-5p0.688
YRF1-6Yrf1-6p0.665
GON7Gon7p0.661
RAD51Rad51p0.625
MEC1Mec1p0.601
RAD55Rad55p0.578
IES3Ies3p0.560
ARP4Arp4p0.549
RAD59Rad59p0.534
IES6Ies6p0.527
SGS1Sgs1p0.523
RAD18Rad18p0.520
RAD5Rad5p0.441
DNA2Dna2p0.418
NHP10Nhp10p0.393
IES1Ies1p0.335
YRF1-7Yrf1-7p0.326
YRF1-1Yrf1-1p0.319
MSH6Msh6p0.298
RAD52Rad52p0.262
IES5Ies5p0.237
MMS22Mms22p0.236
DUN1Dun1p0.235
TEL1Tel1p0.233
SRS2Srs2p0.208
YIL177Chypothetical protein0.170
RAD6Rad6p0.164
RMI1Rmi1p0.144
NSE4Nse4p0.138
IES4Ies4p0.133
RAD50Rad50p0.089
YJL225Chypothetical protein0.085
RAD53Rad53p0.084
YEL077Chypothetical protein0.084
MPH1Mph1p0.081
YRF1-3Yrf1-3p0.078
RFA3Rfa3p0.075
YER064Chypothetical protein0.069
LIF1Lif1p0.059
SMC4Smc4p0.057
PEX11Pex11p0.056
PEX12Pex12p0.055
DCC1Dcc1p0.055
YLR462Whypothetical protein0.055
SET2Set2p0.054
ARP8Arp8p0.053
TOP3Top3p0.051
HOR2Hor2p0.048
APN1Apn1p0.047
MMS1Mms1p0.046
LCD1Lcd1p0.045
YER189Whypothetical protein0.044
SRD1Srd1p0.043
QRI1Qri1p0.043
WSS1Wss1p0.042
CUP1-1Cup1-1p0.039
YLR264C-Ahypothetical protein0.039
MER1Mer1p0.038
YLR162Whypothetical protein0.037
YOL038C-Ahypothetical protein0.037
HDA2Hda2p0.036
ARP10Arp10p0.034
ATG11Atg11p0.034
LEU2Leu2p0.034
IRC19Irc19p0.033
URA3Ura3p0.033
RAD54Rad54p0.032
CHA1Cha1p0.031
YLR464Whypothetical protein0.031
RMD6Rmd6p0.030
SFT1Sft1p0.030
STB1Stb1p0.030
SPL2Spl2p0.029
OPT2Opt2p0.029
HHT2Hht2p0.029
MMS21Mms21p0.029
POL31Pol31p0.029
RAD17Rad17p0.028
FET4Fet4p0.028
RTT109Rtt109p0.028
YNL181Whypothetical protein0.028
ATP6Atp6p0.028
YIR035Chypothetical protein0.028
ZPS1Zps1p0.028
BRN1Brn1p0.027
ARG8Arg8p0.027
MSH3Msh3p0.027
TTI2Tti2p0.026
HHO1Hho1p0.026
YBR013Chypothetical protein0.026
ADH2Adh2p0.026
YAR068Whypothetical protein0.026