The network for 'nervous system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p531.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
EGFRepidermal growth factor receptor1.000
CREBBPCREB binding protein1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
ESR1estrogen receptor 11.000
MDM2Mdm2 p53 binding protein homolog (mouse)0.999
UBCubiquitin C0.999
NCOR1nuclear receptor corepressor 10.998
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.998
FYNFYN oncogene related to SRC, FGR, YES0.997
NCOA1nuclear receptor coactivator 10.996
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.993
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.993
EP300E1A binding protein p3000.992
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.992
RB1retinoblastoma 10.991
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.989
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.987
SMAD4SMAD family member 40.987
ATXN1ataxin 10.985
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.985
FN1fibronectin 10.984
NCOR2nuclear receptor corepressor 20.981
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.981
GRB2growth factor receptor-bound protein 20.981
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.980
FLNAfilamin A, alpha0.980
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.978
JUNjun proto-oncogene0.975
SFNstratifin0.973
ACTBactin, beta0.972
SMAD2SMAD family member 20.962
SP1Sp1 transcription factor0.952
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.948
RARAretinoic acid receptor, alpha0.947
CSNK2A1casein kinase 2, alpha 1 polypeptide0.938
ARandrogen receptor0.938
SIN3ASIN3 homolog A, transcription regulator (yeast)0.932
MAPK8mitogen-activated protein kinase 80.931
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.929
ATF2activating transcription factor 20.929
CDK2cyclin-dependent kinase 20.929
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.928
NCOA3nuclear receptor coactivator 30.927
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.921
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.919
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.913
NUDT21nudix (nucleoside diphosphate linked moiety X)-type motif 210.905
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.904
RAD21RAD21 homolog (S. pombe)0.901
SOCS3suppressor of cytokine signaling 30.886
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.883
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.883
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.875
MAPK14mitogen-activated protein kinase 140.875
NCOA2nuclear receptor coactivator 20.874
RUNX1runt-related transcription factor 10.871
SHC1SHC (Src homology 2 domain containing) transforming protein 10.869
MYH9myosin, heavy chain 9, non-muscle0.850
CSNK2Bcasein kinase 2, beta polypeptide0.848
NTRK3neurotrophic tyrosine kinase, receptor, type 30.847
DLG4discs, large homolog 4 (Drosophila)0.845
GSK3Bglycogen synthase kinase 3 beta0.844
TRIM33tripartite motif containing 330.825
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.821
HNRNPKheterogeneous nuclear ribonucleoprotein K0.820
SMAD3SMAD family member 30.813
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.806
IQGAP1IQ motif containing GTPase activating protein 10.803
HDAC2histone deacetylase 20.793
SOX2SRY (sex determining region Y)-box 20.789
CSNK1Ecasein kinase 1, epsilon0.788
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.781
BCL3B-cell CLL/lymphoma 30.780
CFL1cofilin 1 (non-muscle)0.776
HDAC4histone deacetylase 40.775
FGFR2fibroblast growth factor receptor 20.774
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.770
YAP1Yes-associated protein 10.769
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.764
NTRK2neurotrophic tyrosine kinase, receptor, type 20.761
PKM2pyruvate kinase, muscle0.759
MAPTmicrotubule-associated protein tau0.756
TCF12transcription factor 120.751
MYOD1myogenic differentiation 10.751
MAPK1mitogen-activated protein kinase 10.749
JAG1jagged 10.747
APCadenomatous polyposis coli0.744
FOXD3forkhead box D30.728
CAV1caveolin 1, caveolae protein, 22kDa0.727
CUL1cullin 10.722
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.717
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.715
CDC27cell division cycle 27 homolog (S. cerevisiae)0.715
HDAC1histone deacetylase 10.715
FGF1fibroblast growth factor 1 (acidic)0.714
TAL1T-cell acute lymphocytic leukemia 10.714
MED1mediator complex subunit 10.708
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.706
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.995
vab-3Protein VAB-30.971
unc-9Protein UNC-90.953
unc-73Protein UNC-730.887
goa-1Protein GOA-10.865
ida-1Protein IDA-10.818
unc-42Protein UNC-420.781
hcp-3Protein HCP-30.771
ect-2Protein ECT-20.750
zyg-9Protein ZYG-90.739
ceh-20Protein CEH-200.734
egl-46Protein EGL-460.722
pry-1Protein PRY-10.692
clh-5Protein CLH-50.691
glp-1Protein GLP-10.688
T27A3.1Protein T27A3.10.686
unc-53Protein UNC-530.673
rig-6Protein RIG-60.664
epi-1Protein EPI-10.656
pdfr-1Protein PDFR-10.638
sdz-28Protein SDZ-280.623
mec-2Protein MEC-20.621
pha-4Protein PHA-40.620
eor-1Protein EOR-10.572
daf-11Protein DAF-110.557
egl-13Protein EGL-130.542
bar-1Protein BAR-10.527
R90.1Protein R90.10.522
sma-6Protein SMA-60.518
C11E4.6Protein C11E4.60.492
wrm-1Protein WRM-10.492
elt-6Protein ELT-60.482
scc-3Protein SCC-30.477
let-502Protein LET-5020.475
pkg-1Protein PKG-10.474
hsr-9Protein HSR-90.468
dnc-2Protein DNC-20.466
zag-1Protein ZAG-10.462
unc-6Protein UNC-60.458
scc-1Protein SCC-10.458
F33H2.3Protein F33H2.30.456
hbl-1Protein HBL-10.450
sng-1Protein SNG-10.449
nhr-67Protein NHR-670.449
F33D11.10Protein F33D11.100.442
fln-2Protein FLN-20.439
unc-62Protein UNC-620.439
sli-1Protein SLI-10.429
npp-5Protein NPP-50.425
mep-1Protein MEP-10.419
pxf-1Protein PXF-10.411
inx-13Protein INX-130.406
plc-1Protein PLC-10.401
let-60Protein LET-600.394
ain-1Protein AIN-10.386
nhr-2Protein NHR-20.384
che-3Protein CHE-30.384
F53F10.2Protein F53F10.20.381
daf-19Protein DAF-190.381
egl-36Protein EGL-360.379
zip-7Protein ZIP-70.372
lst-3Protein LST-30.368
unc-40Protein UNC-400.366
gon-4Protein GON-40.359
par-5Protein PAR-50.358
F56D12.6Protein F56D12.60.358
egl-44Protein EGL-440.349
apr-1Protein APR-10.348
apl-1Protein APL-10.348
T07A9.10Protein T07A9.100.346
rig-5Protein RIG-50.344
sax-3Protein SAX-30.344
hda-1Protein HDA-10.340
unc-52Protein UNC-520.338
egl-27Protein EGL-270.331
C54E4.2Protein C54E4.20.330
spc-1Protein SPC-10.330
ubxn-2Protein UBXN-20.330
unc-104Protein UNC-1040.330
age-1Protein AGE-10.329
fkh-2Protein FKH-20.328
dep-1Protein DEP-10.326
daf-12Protein DAF-120.325
lin-12Protein LIN-120.321
CELE_F53F4.11Protein F53F4.110.316
osm-5Protein OSM-50.316
osm-3Protein OSM-30.312
R10E12.2Protein R10E12.20.309
gsp-1Protein GSP-10.309
gck-2Protein GCK-20.308
myo-3Protein MYO-30.306
rpn-8Protein RPN-80.303
xpo-1Protein XPO-10.302
R03H10.2Protein R03H10.20.301
prp-21Protein PRP-210.301
rpt-3Protein RPT-30.300
lam-2Protein LAM-20.300
lrp-2Protein LRP-20.299
gld-1Protein GLD-10.299
magi-1Protein MAGI-10.296
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism