The network for 'cellular protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.

NameDescriptionProbabilityFunc Analog Organism
UBCubiquitin C1.000
TP53tumor protein p531.000
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)1.000
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)1.000
RNF11ring finger protein 111.000
VCPvalosin containing protein1.000
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)1.000
UBE2V1ubiquitin-conjugating enzyme E2 variant 11.000
XIAPX-linked inhibitor of apoptosis1.000
SKP1S-phase kinase-associated protein 11.000
CDC20cell division cycle 20 homolog (S. cerevisiae)0.998
SKP2S-phase kinase-associated protein 2 (p45)0.998
CDC27cell division cycle 27 homolog (S. cerevisiae)0.998
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.998
CUL1cullin 10.997
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.996
UBE3Aubiquitin protein ligase E3A0.996
CUL3cullin 30.996
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.995
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.995
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.995
ARIH2ariadne homolog 2 (Drosophila)0.992
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.990
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.989
RB1retinoblastoma 10.988
CASP8caspase 8, apoptosis-related cysteine peptidase0.986
CDK2cyclin-dependent kinase 20.985
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.984
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.981
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.981
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.979
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.979
RBX1ring-box 1, E3 ubiquitin protein ligase0.976
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.974
PSME3proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)0.974
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.973
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.968
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.965
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.962
MDM2Mdm2 p53 binding protein homolog (mouse)0.954
HSPA8heat shock 70kDa protein 80.953
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.952
OTUB1OTU domain, ubiquitin aldehyde binding 10.951
ANAPC4anaphase promoting complex subunit 40.951
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.948
UBXN7UBX domain protein 70.947
ZNRF1zinc and ring finger 10.946
TRAF6TNF receptor-associated factor 60.944
SMAD2SMAD family member 20.944
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.944
RNF5ring finger protein 50.935
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.933
TRIM39tripartite motif containing 390.932
TCEB1transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)0.930
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.928
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.924
SIAH1seven in absentia homolog 1 (Drosophila)0.923
PTK2PTK2 protein tyrosine kinase 20.922
CCNB1cyclin B10.919
UBQLN1ubiquilin 10.918
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.914
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.906
SYVN1synovial apoptosis inhibitor 1, synoviolin0.902
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase0.898
CSNK1Ecasein kinase 1, epsilon0.897
ADRM1adhesion regulating molecule 10.885
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.885
DCUN1D1DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)0.884
RNF111ring finger protein 1110.880
MDM4Mdm4 p53 binding protein homolog (mouse)0.880
CCNA2cyclin A20.876
FBXW11F-box and WD repeat domain containing 110.872
RAD23BRAD23 homolog B (S. cerevisiae)0.869
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.866
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.858
ANAPC11anaphase promoting complex subunit 110.858
SQSTM1sequestosome 10.840
UFD1Lubiquitin fusion degradation 1 like (yeast)0.840
AMFRautocrine motility factor receptor0.834
CASP3caspase 3, apoptosis-related cysteine peptidase0.833
ARIH1ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)0.832
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.831
CBX5chromobox homolog 50.828
GSK3Bglycogen synthase kinase 3 beta0.826
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.821
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.818
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.817
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.811
USP9Xubiquitin specific peptidase 9, X-linked0.810
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.802
DERL1Der1-like domain family, member 10.802
RNF2ring finger protein 20.801
UHRF2ubiquitin-like with PHD and ring finger domains 20.801
MKRN1makorin ring finger protein 10.801
SMURF2SMAD specific E3 ubiquitin protein ligase 20.794
MARCH7membrane-associated ring finger (C3HC4) 70.792
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.788
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.786
BRCA1breast cancer 1, early onset0.781
RFWD2ring finger and WD repeat domain 20.776
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rpn-7Protein RPN-70.854
rpt-3Protein RPT-30.743
rpt-2Protein RPT-20.738
rpn-3Protein RPN-30.676
rpn-12Protein RPN-120.645
pas-4Protein PAS-40.620
pas-1Protein PAS-10.597
imb-2Protein IMB-20.594
pas-2Protein PAS-20.498
daf-21Protein DAF-210.483
tba-2Protein TBA-20.471
par-5Protein PAR-50.449
cul-1Protein CUL-10.446
pbs-3Protein PBS-30.435
pbs-5Protein PBS-50.428
rpn-6.1Protein RPN-6.10.342
rpn-2Protein RPN-20.327
rpn-1Protein RPN-10.315
atx-3Protein ATX-30.298
ztf-7Protein ZTF-70.286
pbs-2Protein PBS-20.280
rpn-10Protein RPN-100.248
hgrs-1Protein HGRS-10.241
pbs-6Protein PBS-60.241
pbs-1Protein PBS-10.237
T20B12.7Protein T20B12.70.230
rnr-1Protein RNR-10.226
stam-1Protein STAM-10.221
mel-26Protein MEL-260.218
T22F3.2Protein T22F3.20.212
E04D5.1Protein E04D5.10.211
F46F11.6Protein F46F11.60.207
taf-5Protein TAF-50.183
cdc-48.2Protein CDC-48.20.182
mdf-2Protein MDF-20.180
app-1Protein APP-10.172
zen-4Protein ZEN-40.165
rpn-5Protein RPN-50.160
egl-18Protein EGL-180.151
npl-4.2Protein NPL-4.20.150
ubc-25Protein UBC-250.148
rpl-11.1Protein RPL-11.10.146
pbs-7Protein PBS-70.133
rpt-5Protein RPT-50.132
K08E3.5Protein K08E3.50.131
pas-6Protein PAS-60.128
ubc-3Protein UBC-30.126
ect-2Protein ECT-20.125
rpn-11Protein RPN-110.123
pkc-3Protein PKC-30.123
bub-1Protein BUB-10.122
syx-17Protein SYX-170.121
rsa-1Protein RSA-10.121
K07H8.2Protein K07H8.20.121
rad-26Protein RAD-260.121
uev-3Protein UEV-30.119
dnj-19Protein DNJ-190.115
rpa-2Protein RPA-20.114
csn-3Protein CSN-30.112
zyg-1Protein ZYG-10.110
R11A8.7Protein R11A8.70.108
F08B4.7Protein F08B4.70.107
klp-16Protein KLP-160.106
tbb-1Protein TBB-10.105
pas-5Protein PAS-50.103
dpy-30Protein DPY-300.103
flap-1Protein FLAP-10.094
cdl-1Protein CDL-10.092
gpr-2Protein GPR-20.092
pbs-4Protein PBS-40.088
pup-2Protein PUP-20.087
his-6Protein HIS-60.085
skr-1Protein SKR-10.084
mat-3Protein MAT-30.080
bir-1Protein BIR-10.080
zyg-9Protein ZYG-90.079
mom-2Protein MOM-20.079
npl-4.1Protein NPL-4.10.079
ubq-1Protein UBQ-10.077
tba-1Protein TBA-10.077
atg-18Protein ATG-180.076
cul-2Protein CUL-20.074
mig-15Protein MIG-150.073
rod-1Protein ROD-10.072
atg-13Protein ATG-130.068
sbds-1Protein SBDS-10.068
dsh-2Protein DSH-20.067
spas-1Protein SPAS-10.067
Y54E5A.7Protein Y54E5A.70.064
CELE_T10C6.6Protein T10C6.60.063
CELE_Y106G6H.6Protein Y106G6H.60.062
htz-1Protein HTZ-10.062
pas-3Protein PAS-30.061
pqn-65Protein PQN-650.060
crt-1Protein CRT-10.060
ZK507.6Protein ZK507.60.059
tbb-2Protein TBB-20.059
cpg-8Protein CPG-80.059
F36D4.5Protein F36D4.50.059
C52A10.1Protein C52A10.10.058
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
psmb1proteasome (prosome, macropain) subunit, beta type, 10.965
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.956
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.924
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.885
hspa5heat shock protein 50.875
psmc1bproteasome (prosome, macropain) 26S subunit, ATPase, 1b0.862
psmb4proteasome (prosome, macropain) subunit, beta type, 40.857
psmb2proteasome (prosome, macropain) subunit, beta type, 20.857
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.843
psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.827
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.823
psma8proteasome (prosome, macropain) subunit, alpha type, 80.811
zgc:92775zgc:927750.771
rab1aRAB1A, member RAS oncogene family0.768
psmb3proteasome (prosome, macropain) subunit, beta type, 30.764
psmb7proteasome (prosome, macropain) subunit, beta type, 70.732
ccnb1cyclin B10.724
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.716
psma4proteasome (prosome, macropain) subunit, alpha type, 40.685
ubinataxin-1 ubiquitin-like interacting protein0.678
psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.648
LOC100330405transmembrane protein 176B-like0.645
ctsccathepsin C0.637
psmd11bproteasome (prosome, macropain) 216S subunit, non-ATPase, 11b0.610
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.595
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.590
ctsl1bcathepsin L, 1 b0.587
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.586
ck2bcasein kinase 2 beta0.586
syvn1synovial apoptosis inhibitor 1, synoviolin0.528
ctszcathepsin Z0.526
ube2l3aubiquitin-conjugating enzyme E2L 3a0.525
cct5chaperonin containing TCP1, subunit 5 (epsilon)0.505
psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.493
dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.491
smndc1survival motor neuron domain containing 10.490
si:rp71-45k5.4si:rp71-45k5.40.490
chchd2coiled-coil-helix-coiled-coil-helix domain containing 20.470
zgc:55813zgc:558130.462
psmb5proteasome (prosome, macropain) subunit, beta type, 50.443
xbp1X-box binding protein 10.439
usp5ubiquitin specific protease 50.431
ctsdcathepsin D0.431
zgc:86903zgc:869030.430
szlsizzled0.427
ube2d1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.425
fstl1bfollistatin-like 1b0.423
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.422
wnt4awingless-type MMTV integration site family, member 4a0.416
cdc20cell division cycle 20 homolog0.412
vcpvalosin containing protein0.406
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.404
orc1origin recognition complex, subunit 10.403
npc1Niemann-Pick disease, type C10.402
adrm1badhesion regulating molecule 1b0.396
tacc3transforming, acidic coiled-coil containing protein 30.388
zgc:110116zgc:1101160.385
psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.382
ccnecyclin E0.382
psmb6proteasome (prosome, macropain) subunit, beta type, 60.377
zgc:92765zgc:927650.374
capn2bcalpain 2, (m/II) large subunit b0.373
ccnb2cyclin B20.370
zgc:123326zgc:1233260.361
cdt1chromatin licensing and DNA replication factor 10.360
ihhaIndian hedgehog homolog a0.359
maxmyc-associated factor X0.356
sart3squamous cell carcinoma antigen recognised by T cells 30.336
supt5hsuppressor of Ty 5 homolog (S. cerevisiae)0.336
gps1G protein pathway suppressor 10.334
hyou1hypoxia up-regulated 10.333
gmnngeminin, DNA replication inhibitor0.329
psmc1aproteasome (prosome, macropain) 26S subunit, ATPase, 1a0.323
psma5proteasome (prosome, macropain) subunit, alpha type,50.321
ube2g2ubiquitin-conjugating enzyme E2G 20.318
ciapin1cytokine induced apoptosis inhibitor 10.302
tram1translocating chain-associating membrane protein 10.299
plk1polo-like kinase 1 (Drosophila)0.294
ctsbacathepsin B, a0.292
ncl1nicalin0.286
extl3exostoses (multiple)-like 30.286
lancl1LanC antibiotic synthetase component C-like 1 (bacterial)0.286
rlfrearranged L-myc fusion0.286
exoc3exocyst complex component 30.284
eif4ebp2eukaryotic translation initiation factor 4E binding protein 20.279
psmb8proteasome (prosome, macropain) subunit, beta type, 80.279
kif23kinesin family member 230.272
psma1proteasome (prosome, macropain) subunit, alpha type, 10.269
psmd11aproteasome (prosome, macropain) 216S subunit, non-ATPase, 11a0.269
pdap1pdgfa associated protein 10.267
dnaja2lDnaJ (Hsp40) homolog, subfamily A, member 2, like0.266
arf2ADP-ribosylation factor 20.266
gro2groucho 20.266
btg2B-cell translocation gene 20.266
aurkbaurora kinase B0.261
fbxw2F-box and WD repeat domain containing 20.260
smad2MAD homolog 2 (Drosophila)0.258
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.257
rnf40ring finger protein 400.256
hspa4bheat shock protein 4b0.255
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
tefutelomere fusion0.928
Ras85DRas oncogene at 85D0.877
Rpt4CG3455 gene product from transcript CG3455-RA0.853
CycBCyclin B0.816
Prosbeta3Proteasome beta3 subunit0.784
Prosbeta2Proteasome beta2 subunit0.779
Pros29Proteasome 29kD subunit0.737
Rpt3CG16916 gene product from transcript CG16916-RA0.722
CG13349CG13349 gene product from transcript CG13349-RA0.701
dcodiscs overgrown0.695
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.668
Vap-33-1CG5014 gene product from transcript CG5014-RB0.650
UbcD2Ubiquitin conjugating enzyme 20.637
Rpt1CG1341 gene product from transcript CG1341-RA0.602
Mov34CG3416 gene product from transcript CG3416-RA0.573
p53CG33336 gene product from transcript CG33336-RB0.519
Rpn9CG10230 gene product from transcript CG10230-RB0.502
Rpn11CG18174 gene product from transcript CG18174-RA0.490
Prosalpha7Proteasome alpha7 subunit0.482
skpACG16983 gene product from transcript CG16983-RD0.469
Ube3aUbiquitin protein ligase E3A0.442
Prosbeta5Proteasome beta5 subunit0.439
nejnejire0.434
gwlgreatwall0.424
Rpn3Regulatory particle non-ATPase 30.413
Akt1CG4006 gene product from transcript CG4006-RA0.405
CycDCyclin D0.387
CycECyclin E0.386
CG12321CG12321 gene product from transcript CG12321-RA0.382
ncdnon-claret disjunctional0.372
effeffete0.364
SaraSmad anchor for receptor activation0.363
smosmoothened0.358
Prosbeta1Proteasome beta1 subunit0.348
fzyfizzy0.339
agoarchipelago0.331
Tak1TGF-beta activated kinase 10.325
jubAjuba LIM protein0.308
Pros28.1Proteasome 28kD subunit 10.307
PompCG9324 gene product from transcript CG9324-RA0.306
Chmp1CG4108 gene product from transcript CG4108-RA0.306
CG2046CG2046 gene product from transcript CG2046-RA0.304
Cul-5Cullin-50.297
CG11347CG11347 gene product from transcript CG11347-RE0.289
CG32581CG32581 gene product from transcript CG32581-RB0.284
Tbp-1Tat-binding protein-10.283
TER94CG2331 gene product from transcript CG2331-RA0.279
benbendless0.278
barrbarren0.259
EcREcdysone receptor0.255
CG5555CG5555 gene product from transcript CG5555-RA0.251
Prosalpha5Proteasome alpha5 subunit0.242
Rad23CG1836 gene product from transcript CG1836-RB0.237
Uch-L3Ubiquitin C-terminal hydrolase0.231
Prosbeta7Proteasome beta7 subunit0.227
Pros35Proteasome 35kD subunit0.227
BRWD3CG31132 gene product from transcript CG31132-RA0.226
gammaTub37Cgamma-Tubulin at 37C0.223
stepsteppke0.214
Rpn1CG7762 gene product from transcript CG7762-RA0.212
IswiImitation SWI0.211
Fcp1CG12252 gene product from transcript CG12252-RA0.207
IncenpInner centromere protein0.203
gishgilgamesh0.202
CG9135CG9135 gene product from transcript CG9135-RB0.201
stanstarry night0.201
aPKCatypical protein kinase C0.197
lsnlarsen0.195
rlrolled0.193
CG9986CG9986 gene product from transcript CG9986-RA0.192
Rpn2CG11888 gene product from transcript CG11888-RA0.191
CG12162CG12162 gene product from transcript CG12162-RA0.185
Rpn5CG1100 gene product from transcript CG1100-RA0.185
wtswarts0.184
CSN5COP9 complex homolog subunit 50.183
krzkurtz0.180
fz2frizzled 20.179
RagACG11968 gene product from transcript CG11968-RA0.176
swaswallow0.169
eghegghead0.167
RYBPRing and YY1 Binding Protein0.167
lqfliquid facets0.163
bambag of marbles0.162
RhoGEF2CG9635 gene product from transcript CG9635-RF0.162
cal1chromosome alignment defect 10.160
Pp1-87BProtein phosphatase 1 at 87B0.160
ctpcut up0.160
lin19lin-19-like0.157
Vps28Vacuolar protein sorting 280.157
slmbsupernumerary limbs0.155
CG8979CG8979 gene product from transcript CG8979-RC0.154
dosdaughter of sevenless0.154
SmoxSmad on X0.153
bskbasket0.152
EgfrEpidermal growth factor receptor0.151
CG4603CG4603 gene product from transcript CG4603-RA0.148
Pros25Proteasome 25kD subunit0.144
Cul-2Cullin-20.144
CG9772CG9772 gene product from transcript CG9772-RB0.142
DhodDihydroorotate dehydrogenase0.141
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.999
Ctnnb1catenin (cadherin associated protein), beta 10.999
Ptenphosphatase and tensin homolog0.999
Axin1axin 10.997
Ccnb1cyclin B10.986
Gsk3bglycogen synthase kinase 3 beta0.985
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.981
Psma7proteasome (prosome, macropain) subunit, alpha type 70.981
Cdk1cyclin-dependent kinase 10.980
Vcpvalosin containing protein0.979
Psma1proteasome (prosome, macropain) subunit, alpha type 10.973
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.965
Psmb7proteasome (prosome, macropain) subunit, beta type 70.930
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.924
Map3k7mitogen-activated protein kinase kinase kinase 70.921
Psma5proteasome (prosome, macropain) subunit, alpha type 50.921
Skp1aS-phase kinase-associated protein 1A0.917
Usp9xubiquitin specific peptidase 9, X chromosome0.902
Psma2proteasome (prosome, macropain) subunit, alpha type 20.900
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.890
Fgfr1fibroblast growth factor receptor 10.889
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.881
Mdm2transformed mouse 3T3 cell double minute 20.881
Cyldcylindromatosis (turban tumor syndrome)0.880
Ccna2cyclin A20.880
Psma4proteasome (prosome, macropain) subunit, alpha type 40.880
Prc1protein regulator of cytokinesis 10.862
Kpna1karyopherin (importin) alpha 10.856
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.843
Mbd3methyl-CpG binding domain protein 30.843
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.842
Rrm2ribonucleotide reductase M20.842
Birc5baculoviral IAP repeat-containing 50.836
Ccnb2cyclin B20.833
Nedd4neural precursor cell expressed, developmentally down-regulated 40.822
Psmc5protease (prosome, macropain) 26S subunit, ATPase 50.818
Traf6TNF receptor-associated factor 60.809
Psmb6proteasome (prosome, macropain) subunit, beta type 60.798
Cul3cullin 30.796
SkilSKI-like0.793
Pax8paired box gene 80.776
Psma3proteasome (prosome, macropain) subunit, alpha type 30.770
Stat3signal transducer and activator of transcription 30.767
Cry2cryptochrome 2 (photolyase-like)0.764
Aurkaaurora kinase A0.759
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.756
Mis18bp1MIS18 binding protein 10.753
Csnk1dcasein kinase 1, delta0.751
Bag6BCL2-associated athanogene 60.748
Ncoa3nuclear receptor coactivator 30.741
Usp22ubiquitin specific peptidase 220.728
Kif20akinesin family member 20A0.722
Stub1STIP1 homology and U-Box containing protein 10.720
Appamyloid beta (A4) precursor protein0.714
Rnf111ring finger 1110.714
Ikbkginhibitor of kappaB kinase gamma0.712
Bcl2B-cell leukemia/lymphoma 20.703
Ranbp9RAN binding protein 90.694
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.692
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.691
Dyrk1adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a0.686
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.682
Cdca8cell division cycle associated 80.666
Adrm1adhesion regulating molecule 10.653
Tnfaip3tumor necrosis factor, alpha-induced protein 30.653
Uba3ubiquitin-like modifier activating enzyme 30.645
Gli3GLI-Kruppel family member GLI30.642
Col1a1collagen, type I, alpha 10.640
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.636
Ikbkbinhibitor of kappaB kinase beta0.629
Cops2COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)0.623
Grb2growth factor receptor bound protein 20.622
Thrathyroid hormone receptor alpha0.615
Mdm4transformed mouse 3T3 cell double minute 40.612
Mki67antigen identified by monoclonal antibody Ki 670.609
Pompproteasome maturation protein0.609
Apcadenomatosis polyposis coli0.609
Rbl2retinoblastoma-like 20.601
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.594
Banf1barrier to autointegration factor 10.588
Htthuntingtin0.588
Cdca5cell division cycle associated 50.582
Arid1bAT rich interactive domain 1B (SWI-like)0.582
Skiski sarcoma viral oncogene homolog (avian)0.578
Hif1ahypoxia inducible factor 1, alpha subunit0.573
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.566
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.566
Per2period homolog 2 (Drosophila)0.565
C330027C09RikRIKEN cDNA C330027C09 gene0.562
Ncstnnicastrin0.551
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.543
Runx2runt related transcription factor 20.543
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.540
Pias2protein inhibitor of activated STAT 20.539
Psma6proteasome (prosome, macropain) subunit, alpha type 60.534
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.528
Psen1presenilin 10.523
Pcnaproliferating cell nuclear antigen0.518
Ccne1cyclin E10.516
Aimp1aminoacyl tRNA synthetase complex-interacting multifunctional protein 10.514
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psma5proteasome (prosome, macropain) subunit, alpha type 50.925
Psma3proteasome (prosome, macropain) subunit, alpha type 30.876
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.760
Psmb3proteasome (prosome, macropain) subunit, beta type 30.724
Psma4proteasome (prosome, macropain) subunit, alpha type 40.630
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.592
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.549
Psma7proteasome (prosome, macropain) subunit, alpha type 70.490
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.435
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.362
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.353
Psmb2proteasome (prosome, macropain) subunit, beta type 20.330
Psmb6proteasome (prosome, macropain) subunit, beta type 60.303
Psmb7proteasome (prosome, macropain) subunit, beta type 70.294
Psmb4proteasome (prosome, macropain) subunit, beta type 40.260
Psma2proteasome (prosome, macropain) subunit, alpha type 20.246
Psme2proteasome (prosome, macropain) activator subunit 20.241
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.239
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.156
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.145
Psma6proteasome (prosome, macropain) subunit, alpha type 60.145
Csnk1dcasein kinase 1, delta0.144
Zfand5zinc finger, AN1-type domain 50.136
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.131
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.121
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.120
Canxcalnexin0.117
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.114
Eef2eukaryotic translation elongation factor 20.113
Castcalpastatin0.101
Hspe1heat shock protein 1 (chaperonin 10)0.097
CnbpCCHC-type zinc finger, nucleic acid binding protein0.092
DbpD site of albumin promoter (albumin D-box) binding protein0.088
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.087
Psma1proteasome (prosome, macropain) subunit, alpha type 10.087
Hprt1hypoxanthine phosphoribosyltransferase 10.082
Ube2bubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)0.082
Usf2upstream transcription factor 2, c-fos interacting0.080
Kif22kinesin family member 220.078
Dctn4dynactin 40.077
Oaz1ornithine decarboxylase antizyme 10.074
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.072
Txnl1thioredoxin-like 10.071
Psmb10proteasome (prosome, macropain) subunit, beta type 100.069
Nsfl1cNSFL1 (p97) cofactor (p47)0.060
Serinc1serine incorporator 10.058
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.056
Rad23bRAD23 homolog B (S. cerevisiae)0.056
Pdia6protein disulfide isomerase family A, member 60.050
Calrcalreticulin0.049
Hsph1heat shock 105/110 protein 10.048
Psmd7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.046
Psmb5proteasome (prosome, macropain) subunit, beta type 50.046
LOC362855P550.045
Phaxphosphorylated adaptor for RNA export0.045
Cnot7CCR4-NOT transcription complex, subunit 70.044
Rab21RAB21, member RAS oncogene family0.043
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.042
Vcpvalosin-containing protein0.042
Akt1s1AKT1 substrate 1 (proline-rich)0.041
Ccnb1cyclin B10.040
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.039
Pcnaproliferating cell nuclear antigen0.039
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.039
Ubcubiquitin C0.038
Pdia4protein disulfide isomerase family A, member 40.036
Wdr26WD repeat domain 260.035
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.035
Tspyl1TSPY-like 10.035
Mgat2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.034
Tor1aip2torsin A interacting protein 20.034
Ptges3prostaglandin E synthase 3 (cytosolic)0.033
Acyp2acylphosphatase 2, muscle type0.033
Casp3caspase 30.033
Rpn1ribophorin I0.032
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.032
Prdx1peroxiredoxin 10.031
Ppp1r2protein phosphatase 1, regulatory (inhibitor) subunit 20.031
Vps35vacuolar protein sorting 35 homolog (S. cerevisiae)0.030
VapaVAMP (vesicle-associated membrane protein)-associated protein A0.030
Syngr2synaptogyrin 20.030
Mllt4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.030
Sdcbpsyndecan binding protein0.030
Hyou1hypoxia up-regulated 10.030
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.030
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.029
Eif2s2eukaryotic translation initiation factor 2, subunit 2 beta0.029
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.029
B2mbeta-2 microglobulin0.029
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.029
Parp14poly (ADP-ribose) polymerase family, member 140.028
Eif5aeukaryotic translation initiation factor 5A0.028
Foxm1forkhead box M10.027
Serp1stress-associated endoplasmic reticulum protein 10.027
Ufd1lubiquitin fusion degradation 1 like (yeast)0.027
Dlg1discs, large homolog 1 (Drosophila)0.026
Rbbp7retinoblastoma binding protein 70.025
Lman1lectin, mannose-binding, 10.025
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.025
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.025
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC48Cdc48p1.000
PRE1Pre1p0.988
PPH22Pph22p0.983
KAR2Kar2p0.982
RPT4Rpt4p0.968
DSK2Dsk2p0.965
RPT1Rpt1p0.959
RPN10Rpn10p0.958
PRE2Pre2p0.956
RPT3Rpt3p0.947
RPT6Rpt6p0.938
YPT1Ypt1p0.934
RAD23Rad23p0.924
ECM29Ecm29p0.913
UFD2Ufd2p0.907
HRD1Hrd1p0.895
RPT2Rpt2p0.892
PRE10Pre10p0.869
PRE6Pre6p0.845
CDC16Cdc16p0.842
MND2Mnd2p0.836
DOC1Doc1p0.836
CDC23Cdc23p0.828
FYV10Fyv10p0.826
OTU1Otu1p0.826
PUP2Pup2p0.825
PRE9Pre9p0.820
CDC53Cdc53p0.816
UFD4Ufd4p0.808
BRE5Bre5p0.808
UFD1Ufd1p0.802
VPS36Vps36p0.800
SCL1Scl1p0.798
RPN9Rpn9p0.784
UBP15Ubp15p0.782
MAD2Mad2p0.769
RPN12Rpn12p0.768
RPT5Rpt5p0.768
APC5Apc5p0.765
SCJ1Scj1p0.760
UBR1Ubr1p0.758
RPN11Rpn11p0.747
SKP1Skp1p0.745
UBC7Ubc7p0.744
PRE4Pre4p0.703
CDC27Cdc27p0.701
UBC4Ubc4p0.690
UBA1Uba1p0.668
RKR1Rkr1p0.666
DER1Der1p0.661
VID30Vid30p0.653
SWM1Swm1p0.649
RPN8Rpn8p0.645
HRD3Hrd3p0.637
ELC1Elc1p0.636
PRE7Pre7p0.630
SSE2Sse2p0.619
PPH21Pph21p0.594
PRE5Pre5p0.588
PRE8Pre8p0.586
GID7Gid7p0.586
UBX3Ubx3p0.572
PUP1Pup1p0.559
RPN6Rpn6p0.549
YDJ1Ydj1p0.547
UBC13Ubc13p0.547
MET30Met30p0.547
SWE1Swe1p0.546
APC2Apc2p0.541
MUB1Mub1p0.539
KAP114Kap114p0.534
KSP1Ksp1p0.533
RMD5Rmd5p0.529
MON2Mon2p0.523
RPN4Rpn4p0.523
UBX4Ubx4p0.522
RTS1Rts1p0.516
SSA1Ssa1p0.506
UBI4Ubi4p0.506
CDC4Cdc4p0.493
PTC1Ptc1p0.491
APC4Apc4p0.476
GPB2Gpb2p0.474
CDC26Cdc26p0.471
PRC1Prc1p0.462
SPT16Spt16p0.462
YBP2Ybp2p0.461
UBP3Ubp3p0.460
GRR1Grr1p0.457
LAG2Lag2p0.457
DFM1Dfm1p0.453
TRE1Tre1p0.450
RPN7Rpn7p0.441
HTA1Hta1p0.440
UFO1Ufo1p0.434
HSP82Hsp82p0.434
TIP41Tip41p0.433
APC11Apc11p0.431
SGT2Sgt2p0.429
RPN13Rpn13p0.429