The network for 'g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger

The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.

NameDescriptionProbabilityFunc Analog Organism
CALM1calmodulin 1 (phosphorylase kinase, delta)0.999
DRD2dopamine receptor D20.999
GABBR2gamma-aminobutyric acid (GABA) B receptor, 20.993
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.986
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.986
ARRB1arrestin, beta 10.983
MPDZmultiple PDZ domain protein0.966
SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)0.936
GAD2glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)0.925
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.902
GABBR1gamma-aminobutyric acid (GABA) B receptor, 10.802
ADORA2Aadenosine A2a receptor0.801
CRHcorticotropin releasing hormone0.755
PSEN1presenilin 10.751
PTENphosphatase and tensin homolog0.722
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.675
TBC1D10ATBC1 domain family, member 10A0.634
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.630
GPR6G protein-coupled receptor 60.629
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.620
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.616
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.600
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.589
ADRB2adrenergic, beta-2-, receptor, surface0.575
NSFN-ethylmaleimide-sensitive factor0.565
GHRHRgrowth hormone releasing hormone receptor0.559
OPCMLopioid binding protein/cell adhesion molecule-like0.550
CHRNA4cholinergic receptor, nicotinic, alpha 40.515
SSTR3somatostatin receptor 30.514
RAP1ARAP1A, member of RAS oncogene family0.491
PTGER3prostaglandin E receptor 3 (subtype EP3)0.440
CAV1caveolin 1, caveolae protein, 22kDa0.434
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.415
SGCGsarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)0.396
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.384
UBQLN1ubiquilin 10.382
HTR1A5-hydroxytryptamine (serotonin) receptor 1A0.382
NAMPTnicotinamide phosphoribosyltransferase0.374
GNAI3guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 30.370
HTR45-hydroxytryptamine (serotonin) receptor 40.362
GRIA1glutamate receptor, ionotropic, AMPA 10.356
KCNH1potassium voltage-gated channel, subfamily H (eag-related), member 10.338
GRIA2glutamate receptor, ionotropic, AMPA 20.329
PSEN2presenilin 2 (Alzheimer disease 4)0.313
HTR2A5-hydroxytryptamine (serotonin) receptor 2A0.311
EZRezrin0.296
RALBP1ralA binding protein 10.261
NUCB1nucleobindin 10.259
SSTR2somatostatin receptor 20.258
HTR1B5-hydroxytryptamine (serotonin) receptor 1B0.257
GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 20.256
FLNBfilamin B, beta0.255
CALCRcalcitonin receptor0.254
CRHR2corticotropin releasing hormone receptor 20.253
ATP2B2ATPase, Ca++ transporting, plasma membrane 20.251
PRKCGprotein kinase C, gamma0.246
PLD3phospholipase D family, member 30.245
DRD1dopamine receptor D10.238
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.227
CCKBRcholecystokinin B receptor0.225
GRIP1glutamate receptor interacting protein 10.221
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.215
HRH3histamine receptor H30.213
FLNAfilamin A, alpha0.213
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.213
RASSF5Ras association (RalGDS/AF-6) domain family member 50.210
OPRM1opioid receptor, mu 10.209
NECAB2N-terminal EF-hand calcium binding protein 20.207
BMP8Abone morphogenetic protein 8a0.197
GFRA4GDNF family receptor alpha 40.191
SSTR4somatostatin receptor 40.187
SLC30A3solute carrier family 30 (zinc transporter), member 30.186
ADRA1Dadrenergic, alpha-1D-, receptor0.185
OPRD1opioid receptor, delta 10.184
GLP1Rglucagon-like peptide 1 receptor0.181
PTCH1patched 10.177
GRIK3glutamate receptor, ionotropic, kainate 30.176
CTSAcathepsin A0.171
NEUROD2neurogenic differentiation 20.171
FGF4fibroblast growth factor 40.170
APLP2amyloid beta (A4) precursor-like protein 20.166
GRNgranulin0.162
SLC6A7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.159
KCNJ3potassium inwardly-rectifying channel, subfamily J, member 30.157
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homolog0.156
NPY2Rneuropeptide Y receptor Y20.156
SCNN1Gsodium channel, nonvoltage-gated 1, gamma0.156
FTH1ferritin, heavy polypeptide 10.155
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 10.155
CNGB1cyclic nucleotide gated channel beta 10.153
GRM1glutamate receptor, metabotropic 10.153
GFAPglial fibrillary acidic protein0.151
EMX1empty spiracles homeobox 10.151
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.150
FOXN1forkhead box N10.148
DLGAP2discs, large (Drosophila) homolog-associated protein 20.143
CXCR5chemokine (C-X-C motif) receptor 50.141
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.139
GRM6glutamate receptor, metabotropic 60.136
KCNJ9potassium inwardly-rectifying channel, subfamily J, member 90.135
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
drd2bdopamine receptor D2b0.990
oprk1opioid receptor, kappa 10.873
drd2adopamine receptor D2a0.477
oprd1aopioid receptor, delta 1a0.444
drd2ldopamine receptor D2 like0.444
vipr2vasoactive intestinal peptide receptor 20.430
adcyap1r1aadenylate cyclase activating polypeptide 1 receptor 1a0.371
mc4rmelanocortin 4 receptor0.344
calcrlacalcitonin receptor-like a0.283
adra2badrenergic, alpha-2B-, receptor0.265
igfbp6ainsulin-like growth factor binding protein 6a0.259
pcsk1nlproprotein convertase subtilisin/kexin type 1 inhibitor, like0.212
adrb2aadrenergic receptor, beta 2a0.167
lifrbleukemia inhibitory factor receptor alpha b0.162
penkaproenkephalin a0.151
si:ch211-124k10.1si:ch211-124k10.10.142
npy8brneuropeptide Y receptor Y8b0.141
ptger2aprostaglandin E receptor 2a (subtype EP2)0.135
uts1urotensin 10.132
pcp4aPurkinje cell protein 4a0.123
nlgn1neuroligin 10.118
avplarginine vasopressin-like0.112
oprd1bopioid receptor, delta 1b0.110
maomonoamine oxidase0.108
gria2bglutamate receptor, ionotropic, AMPA 2b0.104
gli2aGLI-Kruppel family member GLI2a0.098
nlgn2aneuroligin 2a0.095
LOC100003330melanocortin-2 receptor accessory protein 2-like0.090
alkanaplastic lymphoma kinase (Ki-1)0.084
nlgn2bneuroligin 2b0.079
otpaorthopedia homolog a0.077
adra2dbadrenergic, alpha-2D-, receptor b0.074
kif5ckinesin family member 5C0.072
si:ch211-14k19.8si:ch211-14k19.80.068
kiss2kisspeptin 20.067
insl5binsulin-like 5b0.058
ahr1aaryl hydrocarbon receptor 1a0.057
nlgn3bneuroligin 3b0.057
hcrtr2hypocretin (orexin) receptor 20.055
crabp1acellular retinoic acid binding protein 1a0.053
mc2rmelanocortin 2 receptor0.047
LOC569642hypothetical protein LOC5696420.045
fgfrl1bfibroblast growth factor receptor-like 1b0.043
drd3dopamine receptor D30.042
rln3arelaxin 3a0.041
nrg2aneuregulin 2a0.039
nlgn4aneuroligin 4a0.038
ptgs1prostaglandin-endoperoxide synthase 10.037
crabp1bcellular retinoic acid binding protein 1b0.034
ctsbacathepsin B, a0.032
cyp11b2cytochrome P450, family 11, subfamily B, polypeptide 20.032
m17IL-6 subfamily cytokine M170.031
ca8carbonic anhydrase VIII0.031
inhainhibin, alpha0.030
trpc1transient receptor potential cation channel, subfamily C, member 10.030
slc5a8lsolute carrier family 5 (iodide transporter), member 8-like0.027
oprm1opioid receptor, mu 10.027
cx52.6connexin 52.60.027
cadm2bcell adhesion molecule 2b0.027
camk2n2calcium/calmodulin-dependent protein kinase II inhibitor 20.027
si:dkey-110c1.1si:dkey-110c1.10.026
ctsl1acathepsin L, 1 a0.026
grm1aglutamate receptor, metabotropic 1a0.025
lhbluteinizing hormone, beta polypeptide0.025
oxtloxytocin-like0.025
ros1v-ros UR2 sarcoma virus oncogene homolog 1 (avian)0.024
calcrcalcitonin receptor0.024
fesfeline sarcoma oncogene0.023
agrpagouti related protein homolog0.023
nlgn4bneuroligin 4b0.022
nesnestin0.022
gnrh2gonadotropin-releasing hormone 20.021
csgalnact2chondroitin sulfate N-acetylgalactosaminyltransferase 20.021
LOC100332193growth hormone secretagogue receptor type 1-like0.021
si:ch211-212m21.5si:ch211-212m21.50.021
si:dkey-228g21.4si:dkey-228g21.40.021
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.021
nf1bneurofibromin 1b0.020
paqr7bprogestin and adipoQ receptor family member VII, b0.020
gna12guanine nucleotide binding protein (G protein) alpha 120.020
vipvasoactive intestinal peptide0.020
fshbfollicle stimulating hormone, beta polypeptide0.020
pdlim1PDZ and LIM domain 1 (elfin)0.019
fshrfollicle stimulating hormone receptor0.019
cnga5cyclic nucleotide gated channel alpha 50.019
gna13aguanine nucleotide binding protein (G protein), alpha 13a0.019
LOC799274kinesin heavy chain isoform 5A-like0.018
mc1rmelanocortin 1 receptor0.017
mfn2mitofusin 20.017
cyp1d1cytochrome P450, family 1, subfamily D, polypeptide 10.017
rap1bRAS related protein 1b0.017
LOC555504novel protocadherin protein0.017
paqr8progestin and adipoQ receptor family member VIII0.016
slc18a2solute carrier family 18 (vesicular monoamine), member 20.016
igfbp6binsulin-like growth factor binding protein 6b0.016
crhcorticotropin releasing hormone0.015
inhbaainhibin, beta Aa0.015
pmchpro-melanin concentrating hormone0.015
adora2badenosine A2b receptor0.014
tlr21toll-like receptor 210.014
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG42629CG42629 gene product from transcript CG42629-RB0.625
mttmangetout0.307
PIP5K59BCG3682 gene product from transcript CG3682-RE0.288
TyrRTyramine receptor0.287
5-HT1ASerotonin receptor 1A0.260
Nmdar1NMDA receptor 10.234
Mkp3Mitogen-activated protein kinase phosphatase 30.222
dncdunce0.220
CG13253CG13253 gene product from transcript CG13253-RB0.183
Ank2Ankyrin 20.166
MadMothers against dpp0.141
ClkClock0.140
Ac3CG1506 gene product from transcript CG1506-RA0.134
NPFR1neuropeptide F receptor0.127
dnr1defense repressor 10.127
TbhTyramine beta hydroxylase0.120
timtimeless0.119
Atf-2Activating transcription factor-20.113
Pde8Phosphodiesterase 80.107
DatDopamine N acetyltransferase0.106
RanBPMRan-binding protein M0.105
perperiod0.096
CG18437CG18437 gene product from transcript CG18437-RB0.095
CG32813CG32813 gene product from transcript CG32813-RE0.092
Glut1Glucose transporter 10.088
Octbeta2RCG33976 gene product from transcript CG33976-RA0.083
unc79CG5237 gene product from transcript CG5237-RB0.079
l(3)82FdCG32464 gene product from transcript CG32464-RR0.078
Eip63F-1Ecdysone-induced protein 63F 10.072
CRMPCollapsin Response Mediator Protein0.072
dhddeadhead0.072
Gr28bGustatory receptor 28b0.065
cnglCNG channel-like0.065
DskDrosulfakinin0.062
5-HT1BSerotonin receptor 1B0.058
CorinCG2105 gene product from transcript CG2105-RB0.057
dpr20CG12191 gene product from transcript CG12191-RA0.054
Pdp1PAR-domain protein 10.054
nordCG30418 gene product from transcript CG30418-RA0.050
ppkpickpocket0.048
ClC-aChloride channel-a0.045
CG34400CG34400 gene product from transcript CG34400-RD0.043
rhorhomboid0.042
eyseyes shut0.042
Hs3st-AHeparan sulfate 3-O sulfotransferase-A0.040
stysprouty0.040
norpAno receptor potential A0.038
Gr43aGustatory receptor 43a0.037
CG14274CG14274 gene product from transcript CG14274-RA0.037
molmoladietz0.036
fd85Eforkhead domain 85E0.036
Ast-CAllatostatin C0.036
GluRIIAGlutamate receptor IIA0.034
KCNQKCNQ potassium channel0.034
unc-13-4ACG32381 gene product from transcript CG32381-RB0.033
Nha2Na[+]/H[+] hydrogen antiporter 20.032
PTP-ERProtein tyrosine phosphatase-ERK/Enhancer of Ras10.032
CG34393CG34393 gene product from transcript CG34393-RA0.032
CG34347CG34347 gene product from transcript CG34347-RB0.032
foxoforkhead box, sub-group O0.032
CG15479CG15479 gene product from transcript CG15479-RA0.031
oa2octopamine receptor 20.030
Cpr92ACuticular protein 92A0.030
CG14459CG14459 gene product from transcript CG14459-RB0.029
CG14160CG14160 gene product from transcript CG14160-RA0.029
Ptp99AProtein tyrosine phosphatase 99A0.028
CG14545CG14545 gene product from transcript CG14545-RA0.027
beat-VbCG31298 gene product from transcript CG31298-RA0.027
Vsx2CG33980 gene product from transcript CG33980-RA0.027
Ilp3Insulin-like peptide 30.027
Gyc76CGuanylyl cyclase at 76C0.026
Dh44-R1Diuretic hormone 44 receptor 10.026
CG31999CG31999 gene product from transcript CG31999-RA0.026
CG33696CG33696 gene product from transcript CG33696-RA0.026
Socs36ESuppressor of cytokine signaling at 36E0.026
Nmdar2NMDA receptor 20.026
E(Pc)Enhancer of Polycomb0.025
Spf45CG17540 gene product from transcript CG17540-RB0.025
mAcR-60Cmuscarinic Acetylcholine Receptor 60C0.025
AR-2Allatostatin Receptor 20.024
Pde6Phosphodiesterase 60.024
Sox100BCG15552 gene product from transcript CG15552-RA0.024
SIFRSIFamide receptor0.024
CG15088CG15088 gene product from transcript CG15088-RC0.023
binbiniou0.023
CG14570CG14570 gene product from transcript CG14570-RA0.023
Lcp65Ag1CG10530 gene product from transcript CG10530-RA0.022
CG9447CG9447 gene product from transcript CG9447-RB0.022
stetstem cell tumor0.022
CG12851CG12851 gene product from transcript CG12851-RB0.022
D2RDopamine 2-like receptor0.021
RicRas which interacts with Calmodulin0.021
CG10858CG10858 gene product from transcript CG10858-RB0.021
GABA-B-R3metabotropic GABA-B receptor subtype 30.021
Cpr72EbCuticular protein 72Eb0.021
CG1909CG1909 gene product from transcript CG1909-RA0.021
CG16778CG16778 gene product from transcript CG16778-RA0.021
Tre1trapped in endoderm-10.021
CG5386CG5386 gene product from transcript CG5386-RA0.021
beat-Icbeaten path Ic0.021
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Drd2dopamine receptor D21.000
Esr1estrogen receptor 1 (alpha)0.996
Slc34a1solute carrier family 34 (sodium phosphate), member 10.918
Klklotho0.917
Thrbthyroid hormone receptor beta0.910
Kiss1rKISS1 receptor0.895
Ren1renin 1 structural0.894
Pgrprogesterone receptor0.885
Cckbrcholecystokinin B receptor0.838
Lepleptin0.785
Tacr1tachykinin receptor 10.742
Wnt2bwingless related MMTV integration site 2b0.725
Nos1nitric oxide synthase 1, neuronal0.722
Npy1rneuropeptide Y receptor Y10.706
Adrb1adrenergic receptor, beta 10.692
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.688
Htr75-hydroxytryptamine (serotonin) receptor 70.685
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.681
Sstr4somatostatin receptor 40.669
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.668
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.665
Arandrogen receptor0.632
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.615
Npy2rneuropeptide Y receptor Y20.600
Cgaglycoprotein hormones, alpha subunit0.564
Leprleptin receptor0.562
Kcns2K+ voltage-gated channel, subfamily S, 20.546
Oprm1opioid receptor, mu 10.541
Cx3cr1chemokine (C-X3-C) receptor 10.536
Adora2aadenosine A2a receptor0.533
Has1hyaluronan synthase10.526
Pax8paired box gene 80.510
Crhr1corticotropin releasing hormone receptor 10.504
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.492
Gnrh1gonadotropin releasing hormone 10.485
Sstr1somatostatin receptor 10.482
Pnpla2patatin-like phospholipase domain containing 20.474
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.470
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.447
Tgfb1transforming growth factor, beta 10.447
Tac2tachykinin 20.435
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.428
Htr45 hydroxytryptamine (serotonin) receptor 40.414
Htr1a5-hydroxytryptamine (serotonin) receptor 1A0.413
Agrpagouti related protein0.413
Prop1paired like homeodomain factor 10.396
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.389
Fshrfollicle stimulating hormone receptor0.380
Gdnfglial cell line derived neurotrophic factor0.371
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.370
Shc3src homology 2 domain-containing transforming protein C30.370
Hcrthypocretin0.368
Lhx3LIM homeobox protein 30.358
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.355
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.351
Cdkn1bcyclin-dependent kinase inhibitor 1B0.332
Hic1hypermethylated in cancer 10.323
Mfap2microfibrillar-associated protein 20.320
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.313
Trhthyrotropin releasing hormone0.299
Npy5rneuropeptide Y receptor Y50.297
Sstr2somatostatin receptor 20.289
Krt86keratin 860.288
Gastgastrin0.285
Gpr12G-protein coupled receptor 120.284
Fgf5fibroblast growth factor 50.283
Vdrvitamin D receptor0.280
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.280
Adra2badrenergic receptor, alpha 2b0.274
Esr2estrogen receptor 2 (beta)0.269
Gabrg3gamma-aminobutyric acid (GABA) A receptor, subunit gamma 30.266
Oprd1opioid receptor, delta 10.265
Fgf10fibroblast growth factor 100.260
Dlx4distal-less homeobox 40.252
Adra1aadrenergic receptor, alpha 1a0.252
Pspnpersephin0.249
Gsx1GS homeobox 10.248
Syn2synapsin II0.244
Gli2GLI-Kruppel family member GLI20.244
Pramel7preferentially expressed antigen in melanoma like 70.242
Ptprn2protein tyrosine phosphatase, receptor type, N polypeptide 20.241
Tll1tolloid-like0.238
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.236
Pthlhparathyroid hormone-like peptide0.234
Kiss1KiSS-1 metastasis-suppressor0.229
Gpr132G protein-coupled receptor 1320.229
Slc12a5solute carrier family 12, member 50.227
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.225
Mc5rmelanocortin 5 receptor0.223
Krt77keratin 770.220
S1pr2sphingosine-1-phosphate receptor 20.209
Oprk1opioid receptor, kappa 10.209
Myh11myosin, heavy polypeptide 11, smooth muscle0.208
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.205
Muskmuscle, skeletal, receptor tyrosine kinase0.204
Ptgs2prostaglandin-endoperoxide synthase 20.200
Tpothyroid peroxidase0.199
Dio2deiodinase, iodothyronine, type II0.197
Thrathyroid hormone receptor alpha0.195
Cntn3contactin 30.195
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.581
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.536
Folh1folate hydrolase 10.515
Adora2aadenosine A2a receptor0.426
Cx3cr1chemokine (C-X3-C motif) receptor 10.423
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.421
Cmklr1chemokine-like receptor 10.382
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.370
Slc16a8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)0.363
Pde1bphosphodiesterase 1B, calmodulin-dependent0.353
Ugt8UDP glycosyltransferase 80.345
Olr416olfactory receptor 4160.314
Arhgap23Rho GTPase activating protein 230.312
Fgf2fibroblast growth factor 20.305
Cntn5contactin 50.288
Smad3SMAD family member 30.274
Syt8synaptotagmin VIII0.260
Drd1adopamine receptor D1A0.238
Adora1adenosine A1 receptor0.225
Smcpsperm mitochondria-associated cysteine-rich protein0.218
Slc7a3solute carrier family 7 (cationic amino acid transporter, y+ system), member 30.192
Oprk1opioid receptor, kappa 10.183
Itgamintegrin, alpha M0.176
Epn2epsin 20.171
Aqp2aquaporin 2 (collecting duct)0.171
Phkg1phosphorylase kinase, gamma 10.167
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.164
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.152
Odf4outer dense fiber of sperm tails 40.151
Adarb2adenosine deaminase, RNA-specific, B20.148
Cntn1contactin 10.146
LOC246267resection-induced TPI (rs11)0.143
Mchr1melanin-concentrating hormone receptor 10.143
Gpr6G protein-coupled receptor 60.142
Cntn3contactin 3 (plasmacytoma associated)0.140
Glra1glycine receptor, alpha 10.133
Rgs9regulator of G-protein signaling 90.132
Fgf14fibroblast growth factor 140.131
Tnfrsf8tumor necrosis factor receptor superfamily, member 80.130
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.129
Uhmk1U2AF homology motif (UHM) kinase 10.129
Pnlippancreatic lipase0.127
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.125
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.124
Synposynaptopodin0.119
Acanaggrecan0.116
Chrm4cholinergic receptor, muscarinic 40.115
Nrp2neuropilin 20.114
Grpgastrin releasing peptide0.114
Vom2r53vomeronasal 2 receptor, 530.113
Gng7guanine nucleotide binding protein (G protein), gamma 70.113
Syt4synaptotagmin IV0.108
Hrhairless0.106
Chrna7cholinergic receptor, nicotinic, alpha 70.103
Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.103
Strnstriatin, calmodulin binding protein0.100
Kcnj15potassium inwardly-rectifying channel, subfamily J, member 150.099
Rftn2raftlin family member 20.098
Sstr1somatostatin receptor 10.098
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.098
Shox2short stature homeobox 20.096
Celsr3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)0.095
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.094
Drd2dopamine receptor D20.094
Cgaglycoprotein hormones, alpha polypeptide0.092
Gpr61G protein-coupled receptor 610.092
Chrnb3cholinergic receptor, nicotinic, beta 30.090
Arpp21cAMP-regulated phosphoprotein 210.089
Plcd4phospholipase C, delta 40.087
Scn3asodium channel, voltage-gated, type III, alpha0.087
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.086
Mamdc4MAM domain containing 40.086
Adam10ADAM metallopeptidase domain 100.085
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.085
Map6microtubule-associated protein 60.084
Nfascneurofascin0.084
Pthparathyroid hormone0.083
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.082
Myo1dmyosin ID0.082
Pcdhb12protocadherin beta 120.082
LOC100360919Immunoglobulin lambda-like polypeptide 1-like0.081
Gria4glutamate receptor, ionotrophic, AMPA 40.080
Syt7synaptotagmin VII0.079
Gfra2GDNF family receptor alpha 20.075
Cd4Cd4 molecule0.075
Ncr1natural cytotoxicity triggering receptor 10.070
Ptp4a2protein tyrosine phosphatase 4a20.070
LOC100365195rCG64293-like0.070
Gad2glutamate decarboxylase 20.070
Avparginine vasopressin0.070
Rxrgretinoid X receptor gamma0.070
Slc1a3solute carrier family 1 (glial high affinity glutamate transporter), member 30.070
Neu2sialidase 2 (cytosolic sialidase)0.069
Ncanneurocan0.068
Thtyrosine hydroxylase0.068
Hoxa1homeo box A10.067
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.067
Slc14a2solute carrier family 14 (urea transporter), member 20.067
Hrh3histamine receptor H30.066
Oprd1opioid receptor, delta 10.066
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
GIS2Gis2p0.012
RPF2Rpf2p0.010