The network for 'startle response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

startle response

An action or movement due to the application of a sudden unexpected stimulus.

NameDescriptionProbabilityFunc Analog Organism
DLG4discs, large homolog 4 (Drosophila)1.000
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)1.000
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.997
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.995
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.992
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.991
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.988
DLGAP1discs, large (Drosophila) homolog-associated protein 10.987
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.986
DVL3dishevelled, dsh homolog 3 (Drosophila)0.977
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.933
PTNpleiotrophin0.923
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.906
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.892
SORBS1sorbin and SH3 domain containing 10.889
NLGN1neuroligin 10.888
ZNF746zinc finger protein 7460.858
EGFRepidermal growth factor receptor0.837
PTK6PTK6 protein tyrosine kinase 60.827
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.777
CPEcarboxypeptidase E0.747
CAV1caveolin 1, caveolae protein, 22kDa0.713
HIPK2homeodomain interacting protein kinase 20.705
GRIN2Cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.547
MYO16myosin XVI0.529
SPRR2Asmall proline-rich protein 2A0.506
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.495
TAL1T-cell acute lymphocytic leukemia 10.427
RDH11retinol dehydrogenase 11 (all-trans/9-cis/11-cis)0.398
SYKspleen tyrosine kinase0.390
GRB7growth factor receptor-bound protein 70.317
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.312
COL7A1collagen, type VII, alpha 10.311
NECAB2N-terminal EF-hand calcium binding protein 20.251
BAI1brain-specific angiogenesis inhibitor 10.245
NTRK3neurotrophic tyrosine kinase, receptor, type 30.244
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.229
FGFR1fibroblast growth factor receptor 10.222
DAB1disabled homolog 1 (Drosophila)0.214
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.212
CACNB4calcium channel, voltage-dependent, beta 4 subunit0.209
ADRB2adrenergic, beta-2-, receptor, surface0.205
GRIA1glutamate receptor, ionotropic, AMPA 10.193
ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein0.192
DLG2discs, large homolog 2 (Drosophila)0.187
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.186
SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.185
LRRK2leucine-rich repeat kinase 20.181
SEMA6Asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.179
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.173
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.172
SH3RF1SH3 domain containing ring finger 10.171
OPRK1opioid receptor, kappa 10.168
GRIA2glutamate receptor, ionotropic, AMPA 20.166
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.163
UGT2B7UDP glucuronosyltransferase 2 family, polypeptide B70.162
PAFAH1B3platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)0.156
BCAMbasal cell adhesion molecule (Lutheran blood group)0.152
SYT13synaptotagmin XIII0.149
PRKCSHprotein kinase C substrate 80K-H0.145
CNR1cannabinoid receptor 1 (brain)0.145
CAV2caveolin 20.145
GPC5glypican 50.143
KCNH1potassium voltage-gated channel, subfamily H (eag-related), member 10.141
NEDD4neural precursor cell expressed, developmentally down-regulated 40.141
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.131
VAV2vav 2 guanine nucleotide exchange factor0.130
GRM1glutamate receptor, metabotropic 10.130
SLC9A3solute carrier family 9 (sodium/hydrogen exchanger), member 30.129
NAMPTnicotinamide phosphoribosyltransferase0.128
KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.128
EPHB1EPH receptor B10.128
VAV3vav 3 guanine nucleotide exchange factor0.125
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.121
GSK3Bglycogen synthase kinase 3 beta0.121
PDIA4protein disulfide isomerase family A, member 40.119
FBXO7F-box protein 70.118
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.115
GRIN3Bglutamate receptor, ionotropic, N-methyl-D-aspartate 3B0.113
KCNJ3potassium inwardly-rectifying channel, subfamily J, member 30.112
EZRezrin0.112
PCDH17protocadherin 170.110
CELF4CUGBP, Elav-like family member 40.109
GABRQgamma-aminobutyric acid (GABA) receptor, theta0.108
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.108
ELAVL2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)0.106
CDH10cadherin 10, type 2 (T2-cadherin)0.104
GRIA4glutamate receptor, ionotrophic, AMPA 40.103
NRG1neuregulin 10.103
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 50.102
SNCAIPsynuclein, alpha interacting protein0.102
KCND2potassium voltage-gated channel, Shal-related subfamily, member 20.101
MAPK4mitogen-activated protein kinase 40.095
CACNG2calcium channel, voltage-dependent, gamma subunit 20.092
GRIK1glutamate receptor, ionotropic, kainate 10.091
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.090
GAB2GRB2-associated binding protein 20.087
SHC3SHC (Src homology 2 domain containing) transforming protein 30.087
PTPRFprotein tyrosine phosphatase, receptor type, F0.085
NLGN3neuroligin 30.085
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.676
her15.1hairy and enhancer of split-related 15.10.621
rtn1areticulon 1a0.549
robo3roundabout homolog 30.539
sox3SRY-box containing gene 30.438
jhdm1dajumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)0.407
hmgb1ahigh-mobility group box 1a0.383
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.362
fzd7afrizzled homolog 7a0.309
myo7aamyosin VIIAa0.284
pink1PTEN induced putative kinase 10.274
st8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.262
fzd8afrizzled homolog 8a0.257
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.232
col14a1collagen, type XIV, alpha 10.213
myo6bmyosin VIb0.202
slc17a8solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 80.200
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.199
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.195
slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.194
prickle2prickle-like 2 (Drosophila)0.191
rc3rabconnectin 30.188
nlgn4aneuroligin 4a0.182
pvrl1bpoliovirus receptor-related 1b0.179
drd2adopamine receptor D2a0.179
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.179
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.175
sox11aSRY-box containing gene 11a0.175
fgf17fibroblast growth factor 170.174
zbtb10zinc finger and BTB domain containing 100.171
hey1hairy/enhancer-of-split related with YRPW motif 10.171
drd3dopamine receptor D30.163
neurog1neurogenin 10.163
gfi1.2growth factor independent 1.20.161
pou3f1POU class 3 homeobox 10.158
neurod2neurogenic differentiation 20.154
erbb3av-erb-b2 erythroblastic leukemia viral oncogene homolog 3a0.154
fzd7bfrizzled homolog 7b0.146
cldnkclaudin k0.142
wnt11rwingless-type MMTV integration site family, member 11, related0.137
esrraestrogen-related receptor alpha0.129
maomonoamine oxidase0.128
sox2SRY-box containing gene 20.126
rargaretinoic acid receptor gamma a0.125
prom1bprominin 1 b0.124
muskmuscle, skeletal, receptor tyrosine kinase0.122
pcdh10bprotocadherin 10b0.119
nrg1neuregulin 10.116
igf2rinsulin-like growth factor 2 receptor0.115
atp1b2bATPase, Na+/K+ transporting, beta 2b polypeptide0.115
her6hairy-related 60.112
aldh1a3aldehyde dehydrogenase 1 family, member A30.111
wu:fb17g07wu:fb17g070.102
pcdh8protocadherin 80.100
emx2empty spiracles homeobox 20.100
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.099
sp8bsp8 transcription factor b0.099
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.099
ip6k2inositol hexaphosphate kinase 20.098
acheacetylcholinesterase0.098
prnprs3prion protein, related sequence 30.097
pak1p21/Cdc42/Rac1-activated kinase 10.097
zgc:55813zgc:558130.094
msi1musashi homolog 1 (Drosophila)0.092
atp2b1aATPase, Ca++ transporting, plasma membrane 1a0.091
cited3Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 30.090
dopey1dopey family member 10.088
atp1a3bATPase, Na+/K+ transporting, alpha 3b polypeptide0.088
hnf1aHNF1 homeobox a0.087
gfra1bgdnf family receptor alpha 1b0.087
fabp11afatty acid binding protein 11a0.087
her12hairy-related 120.086
rhouaras homolog gene family, member Ua0.085
ppp3cbprotein phosphatase 3, catalytic subunit, beta isozyme0.083
mbnl1muscleblind-like (Drosophila)0.082
slc8a1asolute carrier family 8 (sodium/calcium exchanger), member 1a0.079
cnr1cannabinoid receptor 10.079
ncs1aneuronal calcium sensor 1a0.079
ap1b1adaptor-related protein complex 1, beta 1 subunit0.079
cd99l2CD99 antigen-like 20.078
six3bsine oculis homeobox homolog 3b0.077
cdc42cell division cycle 420.075
pax6bpaired box gene 6b0.075
gria2bglutamate receptor, ionotropic, AMPA 2b0.075
adra2badrenergic, alpha-2B-, receptor0.074
hs3st3b1bheparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b0.074
trim33tripartite motif-containing 330.072
gsnagelsolin a0.071
foxp2forkhead box P20.070
bsk146brain specific kinase 1460.070
roraaRAR-related orphan receptor A, paralog a0.068
adora2abadenosine A2a receptor b0.068
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.068
dlcdeltaC0.068
msgn1mesogenin 10.067
stmn4stathmin-like 40.067
mtnr1bamelatonin receptor type 1B a0.067
zgc:101606zgc:1016060.065
ahcyl1S-adenosylhomocysteine hydrolase-like 10.065
calb2acalbindin 2a0.064
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
HLHmdeltaE(spl) region transcript mdelta0.842
HLHm7E(spl) region transcript m70.680
E(spl)Enhancer of split0.659
HLHmgammaE(spl) region transcript mgamma0.370
lealeak0.314
HLHm5E(spl) region transcript m50.287
HLHmbetaE(spl) region transcript mbeta0.262
frafrazzled0.206
scscute0.182
nmonemo0.179
btvbeethoven0.171
HLHm3E(spl) region transcript m30.168
CG42629CG42629 gene product from transcript CG42629-RB0.126
CG14478CG14478 gene product from transcript CG14478-RA0.113
dockdreadlocks0.112
iavinactive0.111
commcommissureless0.103
Nrx-IVNeurexin IV0.101
malphaE(spl) region transcript malpha0.076
Ras85DRas oncogene at 85D0.074
Cdc42CG12530 gene product from transcript CG12530-RA0.074
klarklarsicht0.071
tilBtouch insensitive larva B0.068
m2E(spl) region transcript m20.064
nompAno mechanoreceptor potential A0.062
spispitz0.060
bibbig brain0.058
nompCno mechanoreceptor potential C0.057
JIL-1CG6297 gene product from transcript CG6297-RA0.050
lidlittle imaginal discs0.047
chicchickadee0.046
BobABrother of Bearded A0.045
CG34168CG34168 gene product from transcript CG34168-RA0.045
CG32779CG32779 gene product from transcript CG32779-RA0.045
plexAplexin A0.043
uncuncoordinated0.041
atoatonal0.041
robo3CG5423 gene product from transcript CG5423-RA0.040
slislit0.040
TomTwin of m40.039
mubmushroom-body expressed0.039
rempAreduced mechanoreceptor potential A0.038
pdm3pou domain motif 30.037
Fas2Fasciclin 20.037
NrgNeuroglian0.037
emcextra macrochaetae0.034
reporeversed polarity0.034
frufruitless0.033
LIMK1LIM-kinase10.032
embembargoed0.031
CG31740CG31740 gene product from transcript CG31740-RA0.031
Gef64CGuanine nucleotide exchange factor GEF64C0.030
Fas3Fasciclin 30.030
m4E(spl) region transcript m40.030
bifbifocal0.030
taptarget of Poxn0.030
Aats-glyGlycyl-tRNA synthetase0.027
CadNCadherin-N0.026
VGlutVesicular glutamate transporter0.026
Pink1PTEN-induced putative kinase 10.026
CbyChibby0.026
CG12424CG12424 gene product from transcript CG12424-RC0.025
Wnt5Wnt oncogene analog 50.024
Rac1CG2248 gene product from transcript CG2248-RA0.023
PdfPigment-dispersing factor0.023
gcmglial cells missing0.023
Ptp69DProtein tyrosine phosphatase 69D0.022
Wnt6CG4969 gene product from transcript CG4969-RB0.021
p53CG33336 gene product from transcript CG33336-RB0.021
unc-5CG8166 gene product from transcript CG8166-RA0.021
DadDaughters against dpp0.021
nannanchung0.020
aopanterior open0.020
CG31352CG31352 gene product from transcript CG31352-RA0.020
amnamnesiac0.020
nocno ocelli0.020
kcckazachoc0.019
NetBNetrin-B0.019
norpAno receptor potential A0.019
highikaru genki0.019
SpnSpinophilin0.019
stanstarry night0.019
chicoCG5686 gene product from transcript CG5686-RB0.018
Patr-1Protein associated with topo II related - 10.018
AmunCG2446 gene product from transcript CG2446-RB0.018
CG32206CG32206 gene product from transcript CG32206-RB0.018
CG34449CG34449 gene product from transcript CG34449-RB0.018
toktolkin0.018
CG32711CG32711 gene product from transcript CG32711-RA0.017
CG10590CG10590 gene product from transcript CG10590-RA0.017
tlltailless0.016
TBPHCG10327 gene product from transcript CG10327-RC0.016
sbbscribbler0.016
comtcomatose0.016
HerHES-related0.015
unc-104CG8566 gene product from transcript CG8566-RB0.015
Gr28bGustatory receptor 28b0.015
perperiod0.015
armarmadillo0.014
eygeyegone0.014
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.570
Adora2aadenosine A2a receptor0.558
Id3inhibitor of DNA binding 30.504
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.487
Hpcal4hippocalcin-like 40.305
Drd1adopamine receptor D1A0.277
P4hbprolyl 4-hydroxylase, beta polypeptide0.230
Lin7blin-7 homolog b (C. elegans)0.192
Pdia4protein disulfide isomerase family A, member 40.170
Adora1adenosine A1 receptor0.150
Fgf2fibroblast growth factor 20.148
Ghrhrgrowth hormone releasing hormone receptor0.143
Id1inhibitor of DNA binding 10.141
Necab2N-terminal EF-hand calcium binding protein 20.130
Trim9tripartite motif-containing 90.119
Pfn1profilin 10.109
Ptafrplatelet-activating factor receptor0.109
Syngap1synaptic Ras GTPase activating protein 1 homolog (rat)0.105
Bsnbassoon0.096
Dccdeleted in colorectal carcinoma0.093
Glp1rglucagon-like peptide 1 receptor0.092
Mchr1melanin-concentrating hormone receptor 10.089
Pnlippancreatic lipase0.085
Olr287olfactory receptor 2870.083
Trhr2thyrotropin releasing hormone receptor 20.081
Pnocprepronociceptin0.078
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.078
Itgamintegrin, alpha M0.078
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.077
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.076
Kcnf1potassium voltage-gated channel, subfamily F, member 10.073
Tbx2T-box 20.068
Mylk2myosin light chain kinase 20.064
Pdynprodynorphin0.063
Egr4early growth response 40.059
Crhr1corticotropin releasing hormone receptor 10.058
Hsp90b1heat shock protein 90, beta, member 10.057
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.057
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.054
Gipgastric inhibitory polypeptide0.053
Hyou1hypoxia up-regulated 10.052
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.052
Smcpsperm mitochondria-associated cysteine-rich protein0.049
Shox2short stature homeobox 20.047
Ptger2prostaglandin E receptor 2 (subtype EP2)0.046
Crybb3crystallin, beta B30.046
Nrlneural retina leucine zipper0.046
Sv2csynaptic vesicle glycoprotein 2c0.045
Pdia3protein disulfide isomerase family A, member 30.045
Mipmajor intrinsic protein of lens fiber0.044
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.043
Pmp22peripheral myelin protein 220.043
Prp2proline rich protein 20.042
Insrrinsulin receptor-related receptor0.041
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.040
Dlg4discs, large homolog 4 (Drosophila)0.039
Azgp1alpha-2-glycoprotein 1, zinc-binding0.039
Tpsb2tryptase beta 20.039
Oprm1opioid receptor, mu 10.039
Grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.039
Il1r1interleukin 1 receptor, type I0.038
Ahraryl hydrocarbon receptor0.038
Lrrc7leucine rich repeat containing 70.038
Atp4aATPase, H+/K+ exchanging, alpha polypeptide0.037
Nrg2neuregulin 20.037
Csf1colony stimulating factor 1 (macrophage)0.037
TcrbT-cell receptor beta chain0.035
Cxxc4CXXC finger 40.034
Nfascneurofascin0.034
Cd9CD9 molecule0.034
Gzmbgranzyme B0.034
Halhistidine ammonia lyase0.033
Manfmesencephalic astrocyte-derived neurotrophic factor0.033
Usp12ubiquitin specific peptidase 120.033
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.033
Khkketohexokinase0.031
Hand1heart and neural crest derivatives expressed 10.031
FcgrtFc fragment of IgG, receptor, transporter, alpha0.031
Fgf5fibroblast growth factor 50.030
Kcnh8potassium voltage-gated channel, subfamily H (eag-related), member 80.029
Cacna1icalcium channel, voltage-dependent, T type, alpha 1I subunit0.028
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.028
Gng7guanine nucleotide binding protein (G protein), gamma 70.028
Pcsk4proprotein convertase subtilisin/kexin type 40.028
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.028
Pou2f3POU class 2 homeobox 30.028
Tbx3T-box 30.028
Rhovras homolog gene family, member V0.028
Ggt1gamma-glutamyltransferase 10.027
GperG protein-coupled estrogen receptor 10.027
Gnalguanine nucleotide binding protein, alpha stimulating, olfactory type0.027
Pex5lperoxisomal biogenesis factor 5-like0.027
Syt7synaptotagmin VII0.027
Hdlbphigh density lipoprotein binding protein0.027
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.027
Trim29tripartite motif-containing 290.027
Accn2amiloride-sensitive cation channel 2, neuronal0.026
Cd3gCD3 molecule, gamma0.026
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.026
Il8rbinterleukin 8 receptor, beta0.026
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism